Displaying drugs 2401 - 2425 of 3029 in total
Moxifloxacin
Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Approved
Investigational
Matched Synonyms: … dihydro-8-methoxy-7-((4as,7as)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acid …
Matched Iupac: … 1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride …
Matched Products: … Moxifloxacin Acino 400 mg Infusionslösung …
Matched Iupac: … 1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride …
Matched Products: … Moxifloxacin Acino 400 mg Infusionslösung …
FG-2216
A orally active prolyl-hydroxylase inhibitor which can stabilize hypoxia-inducible transcription factor independent of oxygen availability.
Investigational
Matched Synonyms: … (((1-Chloro-4-hydroxyisoquinolin-3-yl)carbonyl)amino)acetic acid …
Matched Iupac: … 2-[(1-chloro-4-hydroxyisoquinolin-3-yl)formamido]acetic acid …
Matched Iupac: … 2-[(1-chloro-4-hydroxyisoquinolin-3-yl)formamido]acetic acid …
Tagetitoxin
Tagetitoxin is a bacterial phytotoxin. It preferentially inhibits eukaryotic RNA polymerase.
Experimental
Matched Synonyms: … Acetoxy-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[3.3.1]nonane-1-carboxylic acid …
Matched Iupac: … acetyloxy)-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[3.3.1]nonane-1-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Iupac: … acetyloxy)-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[3.3.1]nonane-1-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Cilofexor
Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without Cirrhosis).
Investigational
Matched Synonyms: … 3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid …
Matched Iupac: … 3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid …
Matched Description: … Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of …
Matched Categories: … Acids, Heterocyclic …
Matched Iupac: … 3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid …
Matched Description: … Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of …
Matched Categories: … Acids, Heterocyclic …
Evofosfamide
TH-302 is a novel cancer therapeutic specifically activated under the low oxygen or "hypoxic" conditions typical of solid tumor cancer cells. TH-302 is a nitroimidazole-linked prodrug of a brominated derivative of an isophosphoramide mustard previously used in cancer drugs such as ifosfamide, cyclophosphamide, and glufosfamide. TH-302 has been shown, in...
Investigational
Matched Synonyms: … (1-methyl-2-nitro-1H-imidazol-5-YL)methyl N,N'-bis(2-bromoethyl)diamidophosphate ... (1-methyl-2-nitro-1H-imidazole-5-yl)methyl N,N'-bis(2-bromoethyl) diamidophosphate …
Matched Iupac: … (2-bromoethyl)({[(2-bromoethyl)amino][(1-methyl-2-nitro-1H-imidazol-5-yl)methoxy]phosphoryl})amine …
Matched Description: … TH-302 has been shown, in preclinical studies, to be both efficacious and well tolerated. ... of an isophosphoramide mustard previously used in cancer drugs such as ifosfamide, cyclophosphamide, and …
Matched Categories: … Nitro Compounds …
Matched Iupac: … (2-bromoethyl)({[(2-bromoethyl)amino][(1-methyl-2-nitro-1H-imidazol-5-yl)methoxy]phosphoryl})amine …
Matched Description: … TH-302 has been shown, in preclinical studies, to be both efficacious and well tolerated. ... of an isophosphoramide mustard previously used in cancer drugs such as ifosfamide, cyclophosphamide, and …
Matched Categories: … Nitro Compounds …
Cerulenin
Cerulenin is an antifungal agent whose activity interferes with or otherwise acts to prevent the formation of fatty acids and sterols. In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. In sterol synthesis, inhibits HMG-CoA synthetase activity. It is also shown to inhibit feeding and induce...
Experimental
Matched Synonyms: … (2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide …
Matched Iupac: … (2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboximidic acid …
Matched Description: … and sterols. ... It is also shown to inhibit feeding and induce dramatic weight loss in mice. ... In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. …
Matched Categories: … Fatty Acid Synthesis Inhibitors …
Matched Iupac: … (2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboximidic acid …
Matched Description: … and sterols. ... It is also shown to inhibit feeding and induce dramatic weight loss in mice. ... In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. …
Matched Categories: … Fatty Acid Synthesis Inhibitors …
Dermatan sulfate
Experimental
Matched Synonyms: … Chondroitinsulfuric acid type B …
Matched Salts name: … Dermatan sulfate sodium …
Matched Categories: … Blood and Blood Forming Organs …
Matched Salts name: … Dermatan sulfate sodium …
Matched Categories: … Blood and Blood Forming Organs …
Avasopasem
Investigational
Matched Synonyms: … (4AS,13AS,17AS,21AS)-1,2,3,4,4A,5,6,12,13,13A,14,15,16,17,17A,18,19,20,21,21A-EICOSAHYDRO-11,7-NITRILO …
SEP-363856
SEP-363856 is a novel psychotropic drug being investigated for the treatment of schizophrenia. Unlike other drugs used for this condition, SEP-363856 does not bind to the dopamine D2 receptors, but exerts actions on the trace amine–associated receptor 1 (TAAR1) and 5-hydroxytryptamine type 1A (5-HT1A). SEP-363856 was developed by Sunovion pharmaceuticals....
Investigational
Matched Name: … SEP-363856 …
Matched Description: … Additional clinical trials of SEP-363856 are required to confirm the safety and efficacy of this drug ... , and social withdrawal. ... exerts actions on the trace amine–associated receptor 1 (TAAR1) and 5-hydroxytryptamine type 1A (5-HT1A …
Matched Description: … Additional clinical trials of SEP-363856 are required to confirm the safety and efficacy of this drug ... , and social withdrawal. ... exerts actions on the trace amine–associated receptor 1 (TAAR1) and 5-hydroxytryptamine type 1A (5-HT1A …
Zolmitriptan
Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor agonists used to treat acute migraine.[A462, L12978] Sumatriptan was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of second-generation triptans, including almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, and zolmitriptan. Triptans...
Approved
Investigational
Matched Description: … A462, L12978] [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and ... It is currently available in both tablet and nasal spray forms.[L12978] ... second-generation triptans, including [almotriptan], [eletriptan], [frovatriptan], [naratriptan], [rizatriptan], and …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … Septa-zolmitriptan-odt …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … Septa-zolmitriptan-odt …
4-{2,4-Bis[(3-Nitrobenzoyl)Amino]Phenoxy}Phthalic Acid
Experimental
Matched Name: … 4-{2,4-Bis[(3-Nitrobenzoyl)Amino]Phenoxy}Phthalic Acid …
Matched Iupac: … 4-[2,4-bis(3-nitrobenzamido)phenoxy]benzene-1,2-dicarboxylic acid …
Matched Iupac: … 4-[2,4-bis(3-nitrobenzamido)phenoxy]benzene-1,2-dicarboxylic acid …
N-Pyridoxyl-7-Keto-8-Aminopelargonic Acid-5'-Monophosphate
Experimental
Matched Name: … N-Pyridoxyl-7-Keto-8-Aminopelargonic Acid-5'-Monophosphate …
Matched Iupac: … (8S)-8-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-7-oxononanoic acid …
Matched Iupac: … (8S)-8-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-7-oxononanoic acid …
4-oxo-4,5-dihydro-1,2,5-thiadiazole-3-carboxylic acid
Experimental
Matched Name: … 4-oxo-4,5-dihydro-1,2,5-thiadiazole-3-carboxylic acid …
Matched Iupac: … 4-hydroxy-1,2,5-thiadiazole-3-carboxylic acid …
Matched Iupac: … 4-hydroxy-1,2,5-thiadiazole-3-carboxylic acid …
6-phenyl-4(R)-(7-phenyl-heptanoylamino)-hexanoic acid
Experimental
Matched Name: … 6-phenyl-4(R)-(7-phenyl-heptanoylamino)-hexanoic acid …
Matched Iupac: … (4R)-6-phenyl-4-(7-phenylheptanamido)hexanoic acid …
Matched Iupac: … (4R)-6-phenyl-4-(7-phenylheptanamido)hexanoic acid …
3-(7-hydroxy-8-ribityllumazine-6-yl) propionic acid
Experimental
Matched Name: … 3-(7-hydroxy-8-ribityllumazine-6-yl) propionic acid …
Matched Iupac: … 3-{4,7-dihydroxy-2-oxo-8-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]-2,8-dihydropteridin-6-yl}propanoic acid …
Matched Iupac: … 3-{4,7-dihydroxy-2-oxo-8-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]-2,8-dihydropteridin-6-yl}propanoic acid …
5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid
Experimental
Matched Name: … 5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid …
Matched Iupac: … 3-{[1,1'-biphenyl]-4-yl}-5-carbamoylbenzoic acid …
Matched Iupac: … 3-{[1,1'-biphenyl]-4-yl}-5-carbamoylbenzoic acid …
N-PYRIDOXYL-2-METHYL-L-GLUTAMIC ACID-5'-MONOPHOSPHATE
Experimental
Matched Name: … N-PYRIDOXYL-2-METHYL-L-GLUTAMIC ACID-5'-MONOPHOSPHATE …
Matched Iupac: … 2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-2-methylpentanedioic acid …
Matched Iupac: … 2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-2-methylpentanedioic acid …
1-METHYL-3-PHENYL-1H-PYRAZOL-5-YLSULFAMIC ACID
Experimental
Matched Name: … 1-METHYL-3-PHENYL-1H-PYRAZOL-5-YLSULFAMIC ACID …
Matched Iupac: … N-(1-methyl-3-phenyl-1H-pyrazol-5-yl)sulfamic acid …
Matched Iupac: … N-(1-methyl-3-phenyl-1H-pyrazol-5-yl)sulfamic acid …
4-BROMO-3-(CARBOXYMETHOXY)-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID
Experimental
Matched Name: … 4-BROMO-3-(CARBOXYMETHOXY)-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID …
Matched Iupac: … 4-bromo-3-(carboxymethoxy)-5-phenylthiophene-2-carboxylic acid …
Matched Iupac: … 4-bromo-3-(carboxymethoxy)-5-phenylthiophene-2-carboxylic acid …
3-(CARBOXYMETHOXY)THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID
Experimental
Matched Name: … 3-(CARBOXYMETHOXY)THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID …
Matched Iupac: … 3-(carboxymethoxy)thieno[2,3-b]pyridine-2-carboxylic acid …
Matched Iupac: … 3-(carboxymethoxy)thieno[2,3-b]pyridine-2-carboxylic acid …
(1R)-4-(3-phenoxyphenyl)-1-phosphonobutane-1-sulfonic acid
Experimental
Matched Name: … (1R)-4-(3-phenoxyphenyl)-1-phosphonobutane-1-sulfonic acid …
Matched Iupac: … (1R)-4-(3-phenoxyphenyl)-1-phosphonobutane-1-sulfonic acid …
Matched Iupac: … (1R)-4-(3-phenoxyphenyl)-1-phosphonobutane-1-sulfonic acid …
[(2-AMINO-ALPHA-METHOXYIMINO-4-THIAZOLYLACETYL)AMINO]METHYLBORONIC ACID
Experimental
Matched Name: … [(2-AMINO-ALPHA-METHOXYIMINO-4-THIAZOLYLACETYL)AMINO]METHYLBORONIC ACID …
Matched Iupac: … {[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]methyl}boronic acid …
Matched Iupac: … {[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]methyl}boronic acid …
4-(N-ACETYLAMINO)-3-[N-(2-ETHYLBUTANOYLAMINO)]BENZOIC ACID
Experimental
Matched Name: … 4-(N-ACETYLAMINO)-3-[N-(2-ETHYLBUTANOYLAMINO)]BENZOIC ACID …
Matched Iupac: … 4-acetamido-3-(2-ethylbutanamido)benzoic acid …
Matched Iupac: … 4-acetamido-3-(2-ethylbutanamido)benzoic acid …
3-FORMYL-2-HYDROXY-5-METHYL-HEXANOIC ACID HYDROXYAMIDE
Experimental
Matched Name: … 3-FORMYL-2-HYDROXY-5-METHYL-HEXANOIC ACID HYDROXYAMIDE …
N-[(6-butoxynaphthalen-2-yl)sulfonyl]-L-glutamic acid
Experimental
Matched Name: … N-[(6-butoxynaphthalen-2-yl)sulfonyl]-L-glutamic acid …
Matched Iupac: … (2S)-2-(6-butoxynaphthalene-2-sulfonamido)pentanedioic acid …
Matched Iupac: … (2S)-2-(6-butoxynaphthalene-2-sulfonamido)pentanedioic acid …
Displaying drugs 2401 - 2425 of 3029 in total