Displaying drugs 2426 - 2450 of 2478 in total
Clorobiocin
Clorobiocin is an aminocoumarin antibiotic, similar to novobiocin and coumermycin A1.
Experimental
Matched Iupac: … (3R,4S,5R,6S)-6-({8-chloro-4-hydroxy-3-[4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamido]-2-oxo-2H-chromen …
Caprospinol
Caprospinol (SP-233) is the first drug ever to demonstrate the correlation of clearing beta-amyloid from the brain. It also improves the brain histopathology and recovers memory function.
Investigational
Matched Iupac: … (1'S,2R,2'S,4'S,5R,7'S,8'R,9'S,12'S,13'R,16'S)-5,7',9',13'-tetramethyl-5'-oxaspiro[oxane-2,6'-pentacyclo …
Resiniferatoxin
Resiniferatoxin (RTX) is a naturally occurring, ultrapotent capsaicin analog that activates the vanilloid receptor in a subpopulation of primary afferent sensory neurons involved in nociception (the transmission of physiological pain).
Investigational
Matched Iupac: … oxo-15-(prop-1-en-2-yl)-12,14,18-trioxapentacyclo[11.4.1.0^{1,10}.0^{2,6}.0^{11,15}]octadeca-3,8-dien-8- …
Spanlecortemlocel
Investigational
Brigimadlin
Investigational
Matched Iupac: … 'S,14'S)-6-chloro-11'-(3-chloro-2-fluorophenyl)-13'-(cyclopropylmethyl)-6'-methyl-2-oxo-1,2-dihydro-8' …
VPM1002
The bacille Calmette-Guérin (BCG) vaccine protects against severe extrapulmonary forms of tuberculosis (TB) but does not adequately protect against pulmonary TB -- the most prevalent form of TB. This recombinant BCG, VPM1002, has been created in response and investigated for preventing pulmonary TB in newborns and TB recurrence in adults...
Investigational
Matched Description: … As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials …
Brevenal
Investigational
Matched Iupac: … 7,10,15,21-tetramethyl-4,9,14,19,25-pentaoxapentacyclo[13.10.0.0^{3,13}.0^{5,10}.0^{18,24}]pentacosan-8- …
GS-9256
GS-9256 has been used in trials studying the treatment of HCV Infection and Chronic Hepatitis C Infection.
Investigational
Matched Iupac: … [(1S,4S,6R,14S,18R)-18-[(8-chloro-7-methoxy-2-{2-[(propan-2-yl)amino]-1,3-thiazol-4-yl}quinolin-4-yl) …
Ruscogenin
Experimental
Matched Iupac: … (1'S,2R,2'S,4'S,5R,7'S,8'R,9'S,12'S,13'R,14'R,16'R)-5,7',9',13'-tetramethyl-5'-oxaspiro[oxane-2,6'-pentacyclo …
Depelestat
Investigational
10-decarboxymethylaclacinomycin A
Experimental
Matched Iupac: … 6S)-4-hydroxy-6-methyl-5-{[(2R,6R)-6-methyl-5-oxooxan-2-yl]oxy}oxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-8- …
Bafilomycin A1
The bafilomycins refer to a category of toxic macrolide antibiotics that are derivatives of Streptomyces griseus. These compounds all appear in the same fermentation and have similar biological activity. Bafilomycins are specific inhibitors of vacuolar-type H+-ATPase. (V-ATPase). The most commonly utilized bafilomycin is bafilomycin A1. This is a useful tool...
Experimental
Matched Iupac: … [(2S,3R,4S)-4-[(2R,4R,5S,6R)-2,4-dihydroxy-5-methyl-6-(propan-2-yl)oxan-2-yl]-3-hydroxypentan-2-yl]-8- …
4-epi-vancosaminyl derivative of vancomycin
Experimental
Matched Iupac: … hydroxy-4,6-dimethyloxan-2-yl]oxy}-22-(carbamoylmethyl)-40-carboxy-5,15-dichloro-18,32,35,37-tetrahydroxy-19 …
11-Deoxy-Beta-Rhodomycin
Experimental
Matched Iupac: … 6S)-4-hydroxy-6-methyl-5-{[(2R,6R)-6-methyl-5-oxooxan-2-yl]oxy}oxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-8- …
Pterin Cytosine Dinucleotide
Experimental
Matched Iupac: … {[(5aR,8R,9aR)-2-amino-4-oxo-6,7-disulfanyl-3H,4H,5H,5aH,8H,9aH,10H-pyrano[3,2-g]pteridin-8-yl]methoxy …
Fusicoccin
Experimental
Matched Iupac: … (2S)-2-[(1E,3R,4S,8R,9R,10R,11S,14S)-8-{[(2S,3R,4S,5R,6R)-4-(acetyloxy)-3,5-dihydroxy-6-{[(2-methylbut …
5,10-Dimethylene Tetrahydromethanopterin
Experimental
Matched Iupac: … 3R,4R)-5-{4-[(6R,6aS,7S)-3-amino-6,7-dimethyl-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8- …
Furaprevir
Furaprevir is under investigation in clinical trial NCT01523990 (A Study to Evaluate the Safety, Tolerability, and PK in Healthy Volunteers and HCV Genotype 1 Infected Patients).
Investigational
Matched Iupac: … ,14S,18R)-4-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}-2,15-dioxo-18-({4-[4-(propan-2-yloxy)phenyl]-8- …
Efruxifermin
Efruxifermin is under investigation in clinical trial NCT06215716 (A Study Evaluating Efruxifermin in Subjects With Non-cirrhotic Nonalcoholic Steatohepatitis (Nash)/metabolic Dysfunction-associated Steatohepatitis (MASH) and Fibrosis).
Investigational
Displaying drugs 2426 - 2450 of 2478 in total