Did you mean interferon alpha 2b and interferon alpha 2b?
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Interferon alfa-n3
Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD).
Approved
Investigational
Matched Synonyms: … Interferon alfa-n3 …
Matched Name: … Interferon alfa-n3 …
Matched Description: … including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD). ... Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms …
Matched Categories: … Alfa Interferons ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Interferon alpha ... Interferon-alpha …
Matched Name: … Interferon alfa-n3 …
Matched Description: … including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD). ... Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms …
Matched Categories: … Alfa Interferons ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Interferon alpha ... Interferon-alpha …
Interferon alfa-n1
Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated. This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced from individual alpha interferon genes.
Approved
Investigational
Matched Synonyms: … Interferon alfa-n1 ... Interferon alpha-n1 (INS) …
Matched Name: … Interferon alfa-n1 …
Matched Description: … Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least ... recombinant alpha interferons, which are individual non-glycosylated proteins produced from individual alpha interferon …
Matched Categories: … interferon alfa-n1 ... Interferon Type I ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Name: … Interferon alfa-n1 …
Matched Description: … Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least ... recombinant alpha interferons, which are individual non-glycosylated proteins produced from individual alpha interferon …
Matched Categories: … interferon alfa-n1 ... Interferon Type I ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Human interferon beta
Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992. Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and significantly debilitating with a profound impact on the quality of life. Interferon...
Approved
Investigational
Matched Synonyms: … Interferon beta ... Interferon-beta ... Fibroblast interferon …
Matched Name: … Human interferon beta …
Matched Description: … (MS), and was initially approved by the FDA in 1992. ... results from infection with the novel 2019 SARS-CoV-2 virus. ... It is therefore a potential drug candidate for SARS-CoV-2 based on viral genetic similarity. …
Matched Categories: … Interferon Type I ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Name: … Human interferon beta …
Matched Description: … (MS), and was initially approved by the FDA in 1992. ... results from infection with the novel 2019 SARS-CoV-2 virus. ... It is therefore a potential drug candidate for SARS-CoV-2 based on viral genetic similarity. …
Matched Categories: … Interferon Type I ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Peginterferon beta-1a
Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of...
Approved
Matched Synonyms: … Polyethylene glycol-interferon beta-1a …
Matched Description: … [A176474,L5792] Peginterferon beta-1a is an interferon therapy used for the management of relapsing ... [L31428] Currently, it is the only approved pegylated interferon for the management of MS with an proven ... , disrupting communication between the brain and other parts of the body. …
Matched Categories: … Interferon-beta ... Interferon Type I ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … PLEGRİDY 125 MCG/0.5 ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET …
Matched Description: … [A176474,L5792] Peginterferon beta-1a is an interferon therapy used for the management of relapsing ... [L31428] Currently, it is the only approved pegylated interferon for the management of MS with an proven ... , disrupting communication between the brain and other parts of the body. …
Matched Categories: … Interferon-beta ... Interferon Type I ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … PLEGRİDY 125 MCG/0.5 ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET …
Simeprevir
Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated in patient's with HCV genotype 1 for the treatment of chronic hepatitis C virus (HCV) infection. HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United...
Approved
Matched Iupac: … (1R,4R,6R,7Z,15R,17R)-N-(cyclopropanesulfonyl)-17-({7-methoxy-8-methyl-2-[4-(propan-2-yl)-1,3-thiazol ... -2-yl]quinolin-4-yl}oxy)-13-methyl-2,14-dioxo-3,13-diazatricyclo[13.3.0.0^{4,6}]octadec-7-ene-4-carboxamide …
Matched Description: … It is shown to display synergistic effects with interferon-α and HCV NS5B inhibitor, and additive effects ... second-line threapies for treatment-naïve patients as adjunct to sofosbuvir treatment for genotype 1 or PEG-Interferon ... The SVR12 was 83% (29/35) in treatment-naïve patients and 86% (19/22) in relapsing patients. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Description: … It is shown to display synergistic effects with interferon-α and HCV NS5B inhibitor, and additive effects ... second-line threapies for treatment-naïve patients as adjunct to sofosbuvir treatment for genotype 1 or PEG-Interferon ... The SVR12 was 83% (29/35) in treatment-naïve patients and 86% (19/22) in relapsing patients. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Imiquimod
Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. Imiquimod does not cure warts, and new warts may appear during treatment. Imiquimod does not fight the viruses that...
Approved
Investigational
Matched Iupac: … 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine …
Matched Description: … Miquimod is also used to treat a skin condition of the face and scalp called actinic keratoses and certain ... Imiquimod does not cure warts, and new warts may appear during treatment. ... Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. …
Matched Mixtures name: … Imiquimod 5% / Levocetirizine Dihydrochloride 1% / Niacinamide 2% …
Matched Categories: … Interferon Inducers ... Heterocyclic Compounds, 2-Ring ... Skin and Mucous Membrane Agents …
Matched Description: … Miquimod is also used to treat a skin condition of the face and scalp called actinic keratoses and certain ... Imiquimod does not cure warts, and new warts may appear during treatment. ... Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. …
Matched Mixtures name: … Imiquimod 5% / Levocetirizine Dihydrochloride 1% / Niacinamide 2% …
Matched Categories: … Interferon Inducers ... Heterocyclic Compounds, 2-Ring ... Skin and Mucous Membrane Agents …
Polyethylene glycol 400
Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions. Because many PEG types are hydrophilic, they are favorably used as enhancers of penetration, and used heavily in topical dermatological preparations. PEGs, along with their many nonionic derivatives, are...
Approved
Matched Description: … Examples of PEGylated medications are PEG-interferon alpha (Pegintron) and PEG-filgrastim. ... various derivatives and have various functions. ... Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain …
Matched Mixtures name: … Redness reliever and Lubricant ... Systane Day and Night Value Pack ... Systane Day and Night Value Pack …
Matched Products: … Foster and Thrive Dry Eye Relief …
Matched Mixtures name: … Redness reliever and Lubricant ... Systane Day and Night Value Pack ... Systane Day and Night Value Pack …
Matched Products: … Foster and Thrive Dry Eye Relief …
Ombitasvir
Ombitasvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Iupac: … -1-oxobutan-2-yl]carbamate ... methyl N-[(2S)-1-[(2S)-2-({4-[(2S,5S)-1-(4-tert-butylphenyl)-5-{4-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino ... ]-3-methylbutanoyl]pyrrolidine-2-amido]phenyl}pyrrolidin-2-yl]phenyl}carbamoyl)pyrrolidin-1-yl]-3-methyl …
Matched Description: … interferon-based regimens, which were limited by infusion site reactions, reduced blood count, and neuropsychiatric ... FDA- and Health Canada-approved product Technivie. ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ombitasvir, paritaprevir and ritonavir ... dasabuvir, ombitasvir, paritaprevir and ritonavir …
Matched Description: … interferon-based regimens, which were limited by infusion site reactions, reduced blood count, and neuropsychiatric ... FDA- and Health Canada-approved product Technivie. ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ombitasvir, paritaprevir and ritonavir ... dasabuvir, ombitasvir, paritaprevir and ritonavir …
Sofosbuvir
Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Synonyms: … -methyltetrahydrofuran-2-yl)methoxy)- (phenoxy)phosphorylamino)propanoate ... S)-Isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4- dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4 …
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-3-hydroxy ... -4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate …
Matched Description: … interferon- and ribavirin-based regimens, which were limited by infusion site reactions, reduced blood ... a prodrug nucleotide analog, Sofosbuvir is metabolized into its active form as the antiviral agent 2' ... -deoxy-2'-α-fluoro-β-C-methyluridine-5'-triphosphate (also known as GS-461203), which acts as a defective …
Matched Mixtures name: … Ledipasvir and Sofosbuvir ... Sofosbuvir and Velpatasvir …
Matched Categories: … sofosbuvir and ledipasvir ... sofosbuvir and velpatasvir ... sofosbuvir, velpatasvir and voxilaprevir ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-3-hydroxy ... -4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate …
Matched Description: … interferon- and ribavirin-based regimens, which were limited by infusion site reactions, reduced blood ... a prodrug nucleotide analog, Sofosbuvir is metabolized into its active form as the antiviral agent 2' ... -deoxy-2'-α-fluoro-β-C-methyluridine-5'-triphosphate (also known as GS-461203), which acts as a defective …
Matched Mixtures name: … Ledipasvir and Sofosbuvir ... Sofosbuvir and Velpatasvir …
Matched Categories: … sofosbuvir and ledipasvir ... sofosbuvir and velpatasvir ... sofosbuvir, velpatasvir and voxilaprevir ... Nucleic Acids, Nucleotides, and Nucleosides …
Interferon alfa-2b
Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent.
Approved
Matched Synonyms: … Interferon alfa-2b ... Interferon alfa-2b (recombinant) ... Interferon alfa-2b, recombinant …
Matched Name: … Interferon alfa-2b …
Matched Description: … Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). ... This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... A type I interferon consisting of 165 amino acid residues with arginine in position 23. …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … interferon alfa-2b ... Alfa Interferons ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Interferon alpha …
Matched Name: … Interferon alfa-2b …
Matched Description: … Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). ... This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... A type I interferon consisting of 165 amino acid residues with arginine in position 23. …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … interferon alfa-2b ... Alfa Interferons ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Interferon alpha …
Ropeginterferon alfa-2b
Polycythemia vera (PV) is the most common Philadelphia chromosome-negative myeloproliferative neoplasm (MPN), characterized by increased hematocrit and platelet/leukocyte counts, an increased risk for hemorrhage and thromboembolic events, and a long-term propensity for myelofibrosis and leukemia.[A242000, A242005] Interferon alfa-2b has been used for decades to treat PV but requires frequent dosing...
Approved
Investigational
Matched Synonyms: … Ropeginterferon alfa-2b ... Ropeginterferon alfa-2b-njft ... Pegylated proline interferon alpha-2b …
Matched Name: … Ropeginterferon alfa-2b …
Matched Description: … [A242005] Ropeginterferon alfa-2b is a next-generation mono-pegylated type I interferon produced from ... [A242000, A242005] [Interferon alfa-2b] has been used for decades to treat PV but requires frequent dosing ... [A242015, L39170] Ropeginterferon alfa-2b has shown efficacy in PV in _in vitro_ and _in vivo_ models …
Matched Categories: … ropeginterferon alfa-2b ... Antineoplastic and Immunomodulating Agents ... Alfa Interferons …
Matched Name: … Ropeginterferon alfa-2b …
Matched Description: … [A242005] Ropeginterferon alfa-2b is a next-generation mono-pegylated type I interferon produced from ... [A242000, A242005] [Interferon alfa-2b] has been used for decades to treat PV but requires frequent dosing ... [A242015, L39170] Ropeginterferon alfa-2b has shown efficacy in PV in _in vitro_ and _in vivo_ models …
Matched Categories: … ropeginterferon alfa-2b ... Antineoplastic and Immunomodulating Agents ... Alfa Interferons …
Interferon alfa-2a
Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is...
Approved
Investigational
Matched Synonyms: … Interferon alfa-2a ... Interferon-alfa-2a ... Interferon alfa-2a,recombinant …
Matched Name: … Interferon alfa-2a …
Matched Description: … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... Interferon a (human leukocyte protein moiety reduced). ... A type I interferon consisting of 165 amino acid residues with lysine in position 23. …
Matched Categories: … interferon alfa-2a ... Alfa Interferons ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Interferon alpha …
Matched Name: … Interferon alfa-2a …
Matched Description: … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... Interferon a (human leukocyte protein moiety reduced). ... A type I interferon consisting of 165 amino acid residues with lysine in position 23. …
Matched Categories: … interferon alfa-2a ... Alfa Interferons ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Interferon alpha …
Peginterferon alfa-2b
Peginterferon alfa-2b is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Synonyms: … Peginterferon alfa-2b …
Matched Name: … Peginterferon alfa-2b …
Matched Description: … Peginterferon alfa-2b is derived from the alfa-2b moeity of recombinant human interferon and acts by ... Peginterferon alfa-2b is a form of recombinant interferon used as part of combination therapy to treat ... 41% for genotype 1 and 75% for genotypes 2-6 after 48 weeks of treatment. …
Matched Categories: … peginterferon alfa-2b ... peginterferon alfa-2b, combinations ... Alfa Interferons ... Interferon alpha ... Interferon-alpha …
Matched Name: … Peginterferon alfa-2b …
Matched Description: … Peginterferon alfa-2b is derived from the alfa-2b moeity of recombinant human interferon and acts by ... Peginterferon alfa-2b is a form of recombinant interferon used as part of combination therapy to treat ... 41% for genotype 1 and 75% for genotypes 2-6 after 48 weeks of treatment. …
Matched Categories: … peginterferon alfa-2b ... peginterferon alfa-2b, combinations ... Alfa Interferons ... Interferon alpha ... Interferon-alpha …
Peginterferon alfa-2a
Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Investigational
Matched Synonyms: … PEG-Interferon alfa-2A ... Pegylated interferon alfa-2a ... Pegylated-interferon alfa 2a …
Matched Name: … Peginterferon alfa-2a …
Matched Description: … Peginterferon alfa-2a is derived from the alfa-2a moeity of recombinant human interferon and acts by ... 36% for genotype 1 and 59% for genotypes 2-6 after 48 weeks of treatment. ... Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat …
Matched Categories: … Interferon alpha ... Interferon Type I ... Alfa Interferons ... peginterferon alfa-2a ... Amino Acids, Peptides, and Proteins …
Matched Name: … Peginterferon alfa-2a …
Matched Description: … Peginterferon alfa-2a is derived from the alfa-2a moeity of recombinant human interferon and acts by ... 36% for genotype 1 and 59% for genotypes 2-6 after 48 weeks of treatment. ... Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat …
Matched Categories: … Interferon alpha ... Interferon Type I ... Alfa Interferons ... peginterferon alfa-2a ... Amino Acids, Peptides, and Proteins …
Interferon beta-1a
Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interferon beta.
Approved
Investigational
Matched Synonyms: … Interferon beta 1-a ... Interferon beta 1a ... Interferon beta-1a …
Matched Name: … Interferon beta-1a …
Matched Description: … Human interferon beta (166 residues), glycosylated, MW=22.5kD. ... The amino acid sequence is identical to that of natural human interferon beta. ... It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Interferon-beta ... Interferon Type I ... interferon beta-1a …
Matched Products: … AVONEX®INTERFERON BETA-1A JERINGA PRELLENADA …
Matched Name: … Interferon beta-1a …
Matched Description: … Human interferon beta (166 residues), glycosylated, MW=22.5kD. ... The amino acid sequence is identical to that of natural human interferon beta. ... It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Interferon-beta ... Interferon Type I ... interferon beta-1a …
Matched Products: … AVONEX®INTERFERON BETA-1A JERINGA PRELLENADA …
Interferon alfacon-1
Interferon alfacon-1 is a recombinant non-naturally occurring type-I interferon. The 166-amino acid sequence of Interferon alfacon-1 was derived by scanning the sequences of several natural interferon alpha subtypes and assigning the most frequently observed amino acid in each corresponding position. Four additional amino acid changes were made to facilitate the...
Approved
Investigational
Matched Synonyms: … Interferon alfacon-1 …
Matched Name: … Interferon alfacon-1 …
Matched Description: … Interferon alfacon-1 differs from interferon alfa-2b at 20/166 amino acids (88% homology), and comparison ... Prior to final purification, Interferon alfacon-1 is allowed to oxidize to its native state, and its ... natural interferon alpha subtypes and assigning the most frequently observed amino acid in each corresponding …
Matched Categories: … Alfa Interferons ... Interferon alpha ... Interferon Type I ... interferon alfacon-1 ... Amino Acids, Peptides, and Proteins …
Matched Name: … Interferon alfacon-1 …
Matched Description: … Interferon alfacon-1 differs from interferon alfa-2b at 20/166 amino acids (88% homology), and comparison ... Prior to final purification, Interferon alfacon-1 is allowed to oxidize to its native state, and its ... natural interferon alpha subtypes and assigning the most frequently observed amino acid in each corresponding …
Matched Categories: … Alfa Interferons ... Interferon alpha ... Interferon Type I ... interferon alfacon-1 ... Amino Acids, Peptides, and Proteins …
Interferon beta-1b
Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Approved
Matched Synonyms: … Interferon beta-1b ... Interferon-beta-1b ... Interferon beta 1b (recombinant) …
Matched Name: … Interferon beta-1b …
Matched Description: … Human interferon beta (165 residues), cysteine 17 is substituted with serine. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Interferon-beta ... Interferon Type I ... interferon beta-1b …
Matched Name: … Interferon beta-1b …
Matched Description: … Human interferon beta (165 residues), cysteine 17 is substituted with serine. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Interferon-beta ... Interferon Type I ... interferon beta-1b …
Interferon gamma-1b
Human Interferon gamma-1b (140 residues), produced from E. coli. Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium containing the DNA which encodes for the human protein. Purification of the product is achieved by conventional column chromatography.
The sequence displayed is a cDNA sequence which...
Approved
Investigational
Matched Synonyms: … Interferon gamma 1-b ... Interferon gamma-1b ... Interferon gamma-2a …
Matched Name: … Interferon gamma-1b …
Matched Description: … et. al. and not specifically interferon gamma 1b. ... Human Interferon gamma-1b (140 residues), produced from E. coli. ... The sequence displayed is a cDNA sequence which codes for human interferon gamma, as described by Gray …
Matched Categories: … Interferon gamma ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Name: … Interferon gamma-1b …
Matched Description: … et. al. and not specifically interferon gamma 1b. ... Human Interferon gamma-1b (140 residues), produced from E. coli. ... The sequence displayed is a cDNA sequence which codes for human interferon gamma, as described by Gray …
Matched Categories: … Interferon gamma ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Nadofaragene firadenovec
Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without...
Approved
Investigational
Matched Synonyms: … Replication-deficient adenovirus type 5 (ad5) vector encoding the human interferon alpha 2 (ifna2, interferon ... RAD-IFN-2B ... alpha-2b) gene under the control of the cytomegalovirus (cmv) immediate-early enhancer/promoter …
Matched Description: … alfa-2b (IFNα2b). ... is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon ... [L44381,L44431] BCG-unresponsive NMIBC has a high recurrence and is notably difficult to treat. …
Matched Categories: … Cellular and Gene Therapy ... Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
Matched Description: … alfa-2b (IFNα2b). ... is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon ... [L44381,L44431] BCG-unresponsive NMIBC has a high recurrence and is notably difficult to treat. …
Matched Categories: … Cellular and Gene Therapy ... Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
Somatostatin
Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues that regulates the endocrine system. It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where...
Approved
Investigational
Matched Iupac: … (4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-37-{2-[(2S)-2-aminopropanamido …
Matched Description: … It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also ... generated in the hypothalamus, where it inhibits the release of growth hormone and thyroid-stimulating ... Prosomastatin is further process into two active forms, somatostatin-14 (SST-14) and somatostatin-28 …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Somatostatin and Analogues ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SOMATOSTATINA ALFA BIOTECH …
Matched Description: … It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also ... generated in the hypothalamus, where it inhibits the release of growth hormone and thyroid-stimulating ... Prosomastatin is further process into two active forms, somatostatin-14 (SST-14) and somatostatin-28 …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Somatostatin and Analogues ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SOMATOSTATINA ALFA BIOTECH …
Mitoxantrone
An anthracenedione-derived antineoplastic agent.
Approved
Investigational
Matched Synonyms: … 1,4-Bis(2-(2-hydroxyethylamino)ethyl)amino)-5,8-dihydroxyanthraquinone …
Matched Iupac: … 1,4-dihydroxy-5,8-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)-9,10-dihydroanthracene-9,10-dione …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … MITOXANTRONE BAXTER INJECTION 2 mg/ml ... Ebexantron 2 mg/ml - Konzentrat zur Herstellung einer Infusionslösung ... Mitoxantron Accord 2 mg/ml Konzentrat zur Herstellung einer Infusionslösung …
Matched Iupac: … 1,4-dihydroxy-5,8-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)-9,10-dihydroanthracene-9,10-dione …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … MITOXANTRONE BAXTER INJECTION 2 mg/ml ... Ebexantron 2 mg/ml - Konzentrat zur Herstellung einer Infusionslösung ... Mitoxantron Accord 2 mg/ml Konzentrat zur Herstellung einer Infusionslösung …
Benznidazole
Benznidazole was granted accelerated approval for the treatment of Chagas disease in children 2-12 years of age by the FDA on August 29, 2017. It is the first treatment made available in the United States for Chagas disease.
Approved
Investigational
Matched Iupac: … N-benzyl-2-(2-nitro-1H-imidazol-1-yl)acetamide …
Matched Description: … Benznidazole was granted accelerated approval for the treatment of Chagas disease in children 2-12 years …
Matched Categories: … Agents Against Leishmaniasis and Trypanosomiasis ... Antiparasitic Products, Insecticides and Repellents …
Matched Description: … Benznidazole was granted accelerated approval for the treatment of Chagas disease in children 2-12 years …
Matched Categories: … Agents Against Leishmaniasis and Trypanosomiasis ... Antiparasitic Products, Insecticides and Repellents …
Glucosamine
Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation. Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of OA. Glucosamine is commonly used over the counter as...
Approved
Investigational
Matched Synonyms: … 2-amino-2-deoxy-D-glucose …
Matched Description: … changes, and synovial membrane inflammation. ... Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone ... for arthritic joint pain, although its acceptance as a medical therapy varies due to contradictory and …
Matched Salts cas: … 66-84-2 …
Matched Mixtures name: … Bee Venom Joint And Bone Therapy Drops ... Blackmores Joint Formula with Glucosamine and Chondroitin …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Description: … changes, and synovial membrane inflammation. ... Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone ... for arthritic joint pain, although its acceptance as a medical therapy varies due to contradictory and …
Matched Salts cas: … 66-84-2 …
Matched Mixtures name: … Bee Venom Joint And Bone Therapy Drops ... Blackmores Joint Formula with Glucosamine and Chondroitin …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Idecabtagene vicleucel
Multiple myeloma is a cancer where plasma cells rapidly divide out of control. These cancerous cells generally express the B-cell maturation antigen, while it is rarely expressed on non-cancerous cells. Multiple myeloma is typically treated with an immunomodulatory agent like lenalidomide, a proteasome inhibitor like bortezomib, or an anti-CD38 monoclonal...
Approved
Matched Description: … [A232563] These cancerous cells generally express the B-cell maturation antigen, while it is rarely expressed ... [A232558] The chimeric antigen receptor of idecabtagene vicleucel includes an anti-B-cell maturation ... antigen scFv-targeting domain, CD3ζ T-cell activation domain, and 4-1BB costimulatory domain. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic cell and gene therapy ... Receptors, Cytoplasmic and Nuclear ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic cell and gene therapy ... Receptors, Cytoplasmic and Nuclear ... Antineoplastic and Immunomodulating Agents …
Ritlecitinib
Ritlecitinib (PF-06651600) is a highly selective inhibitor of Janus kinase 3 (JAK3) and the tyrosine kinase expressed in hepatocellular carcinoma (TEC) kinase family. In June 2023, it was approved by the FDA for the treatment of severe alopecia areata in adults and adolescents 12 years and older.[L47092,L47127] It was further...
Approved
Investigational
Matched Synonyms: … 2-propen-1-one, 1-((2S,5R)-2-methyl-5-(7H-pyrrolo(2,3-D)pyrimidin-4-ylamino)-1-piperidinyl)- …
Matched Iupac: … 1-[(2S,5R)-2-methyl-5-({7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)piperidin-1-yl]prop-2-en-1-one …
Matched Description: … 12 years and older. ... This makes ritlecitinib a highly selective and irreversible JAK3 inhibitor. ... [L48181] Ritlecitinib is administered orally and is the first member of its class. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 1-[(2S,5R)-2-methyl-5-({7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)piperidin-1-yl]prop-2-en-1-one …
Matched Description: … 12 years and older. ... This makes ritlecitinib a highly selective and irreversible JAK3 inhibitor. ... [L48181] Ritlecitinib is administered orally and is the first member of its class. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Displaying drugs 1 - 25 of 56 in total