Displaying drugs 26 - 50 of 3000 in total
Zinc
A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound...
Approved
Investigational
Matched Synonyms: … Zinc, chelated ... Zinc, elemental …
Matched Name: … Zinc …
Matched Iupac: … zinc …
Matched Description: … forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell ... In addition to the above, recent review articles have already demonstrated the important role of zinc ... A newer study suggests implies that an imbalance of zinc is associated with the neuronal damage associated …
Matched Mixtures name: … Cell-wise ... Cell-wise Natural Source ... A + Zinc …
Matched Categories: … Zinc Compounds ... zinc preparations …
Matched Products: … Zinc 50mg ... Zinc Formula ... Zinc - 25mg Tab …
Matched Name: … Zinc …
Matched Iupac: … zinc …
Matched Description: … forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell ... In addition to the above, recent review articles have already demonstrated the important role of zinc ... A newer study suggests implies that an imbalance of zinc is associated with the neuronal damage associated …
Matched Mixtures name: … Cell-wise ... Cell-wise Natural Source ... A + Zinc …
Matched Categories: … Zinc Compounds ... zinc preparations …
Matched Products: … Zinc 50mg ... Zinc Formula ... Zinc - 25mg Tab …
Zimberelimab
Investigational
Matched Synonyms: … Immunoglobulin g4(231-proline), anti-(human programmed cell death protein 1) (human monoclonal ab122 …
Zilucoplan
Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses. On October 17, 2023, zilucoplan gained its first FDA approval for the treatment of...
Approved
Zenocutuzumab
Zenocutuzumab is under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer).
Investigational
Matched Synonyms: … Mcla-128 (igg1 bispecific antibody with enhanced antibody-dependent cell-mediated cytotoxicity (adcc) …
ZEN-012
ZEN-012 is a novel small molecule and the first anti-cancer drug in development involving two mechanisms of action: tubulin and topoisomerase II inhibition. ZEN-012 also expresses additional modes of action such as pro-apoptotic and anti-angiogenic properties. It is developed for the treatment of solid tumors.
Investigational
Zelpultide alfa
Zelpultide alfa is a recombinant human surfactant protein D.
Investigational
Matched Synonyms: … PULMONARY SURFACTANT-ASSOCIATED PROTEIN D (HUMAN RECOMBINANT GLYCOEXPRESS MYELOMA CELL HOMOTRIMERIC QUADRAPLEX …
Zeatin
An aminopurine factor in plant extracts that induces cell division. (Grant & Hackh's Chemical Dict, 5th ed)
Experimental
Matched Description: … An aminopurine factor in plant extracts that induces cell division. …
Zea mays pollen
Zea mays pollen is the pollen of the Zea mays plant. Zea mays pollen is mainly used in allergenic testing.
Approved
Matched Categories: … Cell-mediated Immunity …
ZD-6126
ZD6126 has been used in trials studying the treatment of Kidney Neoplasms, Colorectal Neoplasms, Metastases, Neoplasm, and Carcinoma, Renal Cell.
Investigational
Matched Description: … the treatment of Kidney Neoplasms, Colorectal Neoplasms, Metastases, Neoplasm, and Carcinoma, Renal Cell …
ZB131
ZB131 is a monoclonal antibody with a high affinity and specificity for cancer-specific plectin (CSP), a cell surface protein identified in a wide range of cancers that correlates with poor prognosis and aggressive tumors.
Investigational
Matched Description: … is a monoclonal antibody with a high affinity and specificity for cancer-specific plectin (CSP), a cell …
Zastumotide
Zastumotide is a recombinant MAGE-A3 Antigen-Specific Cancer Immunotherapeutic (MAGE-A3 ASCI) also known as astuprotimut-R. It is under investigation in clinical trial NCT00257738 (0804 GCC: MAGE-A3/HPV 16 Vaccine for Squamous Cell Carcinoma of the Head and Neck).
Investigational
Matched Description: … is under investigation in clinical trial NCT00257738 (0804 GCC: MAGE-A3/HPV 16 Vaccine for Squamous Cell …
Zanubrutinib
Zanubrutinib is a novel Bruton's tyrosine kinase (BTK) inhibitor used for the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. Mantle cell lymphoma is an aggressive mature B-cell non-Hodgkin lymphoma associated with early relapse, poor clinical outcomes, and long-term survival. BTK...
Approved
Investigational
Matched Description: … [L10163] Mantle cell lymphoma is an aggressive mature B-cell non-Hodgkin lymphoma associated with early ... novel Bruton's tyrosine kinase (BTK) inhibitor used for the treatment of adult patients with mantle cell …
Zanidatamab
According to Zymeworks, "ZW25 is a bispecific antibody that can simultaneously bind two non-overlapping epitopes, known as biparatopic binding, of HER2 resulting in dual HER2 signal blockade, increased binding and removal of HER2 protein from the cell surface, and potent effector function. These combined mechanisms of action have led to...
Investigational
Matched Description: … HER2 resulting in dual HER2 signal blockade, increased binding and removal of HER2 protein from the cell …
Zalutumumab
Zalutumumab is a fully human IgG1 monoclonal antibody designed to bind with selectivity to the epidermal growth factor receptor (EGFR). Zalutumumab has been investigated for the treatment of Squamous Cell Cancer and Head and Neck Cancer.
Investigational
Matched Description: … Zalutumumab has been investigated for the treatment of Squamous Cell Cancer and Head and Neck Cancer. …
Z-Val-Ala-Asp fluoromethyl ketone
Non-methylated, competitive, and irreversible inhibitor of caspase 1, as well as other caspases,1 which can be used directly with purified enzymes. It does not require an esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(O-Me) fluoromethyl ketone.
Experimental
Matched Description: … It does not require an esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp …
YSIL6
YSIL6 is a small-molecule drug in development for the treatment of inflammatory diseases, including rheumatoid arthritis and psoriasis. The molecule works by inhibiting TNF-alpha and IL-6 production in T-cells and macrophages, and by inhibiting T-cell proliferation and migration.
Investigational
Matched Description: … molecule works by inhibiting TNF-alpha and IL-6 production in T-cells and macrophages, and by inhibiting T-cell …
Yellowfin tuna
Yellowfin tuna allergenic extract is used in allergenic testing.
Approved
Matched Categories: … Cell-mediated Immunity …
Yeast
Yeast allergenic extract is used in allergenic testing.
Approved
Matched Categories: … Cell-mediated Immunity …
Xylitol
Xylitol is a naturally occurring five-carbon sugar alcohol found in most plant material, including many fruits and vegetables. Xylitol-rich plant materials include birch and beechwood . It is widely used as a sugar substitute and in "sugar-free" food products. The effects of xylitol on dental caries have been widely studied,...
Experimental
Investigational
XmAb 2513
XmAb 2513 is a humanized monoclonal antibody that targets the antigen CD30, a molecule expressed on the surface of a number of tumor cell types. It has been investigated for the treatment of hodgkin’s lymphoma.
Investigational
Matched Description: … monoclonal antibody that targets the antigen CD30, a molecule expressed on the surface of a number of tumor cell …
XL999
XL999 has the potential to provide benefit to patients with lung cancer and acute myelogenous leukemia. XL999 is a new chemical entity that inhibits a spectrum of receptor tyrosine kinases (RTKs) with growth promoting and angiogenic properties, including FGFR 1/3, PDGFRα/β, VEGFR2/KDR, KIT, and FLT3. XL999 also inhibits FLT4 and...
Investigational
Matched Description: … XL999 induces a cell-cycle block by a mechanism distinct from those previously identified and exhibits ... XL999 has the potential to prevent tumor growth — both directly by a novel effect on tumor cell proliferation …
XL844
XL844 is investigated for the use and treatment solid tumors. XL844 is a solid. XL844 is a potent inhibitor of the checkpoint kinases CHK1 and CHK2, which induce cell cycle arrest in response to a variety of DNA damaging agents. Known drug targets of XL844 including serine/threonine-protein kinase Chk1 and...
Investigational
Matched Description: … XL844 is a potent inhibitor of the checkpoint kinases CHK1 and CHK2, which induce cell cycle arrest in …
XL820
XL820 is investigated for use/treatment in solid tumors. XL820 is a solid. The proteins that XL820 inhibit include platelet-derived growth factor receptor beta (PDGFR), mast/stem cell growth factor receptor KIT, vascular endothelial growth factor receptor 2, and platelet-derived growth factor receptor alpha, clinically validated targets implicated in a variety of...
Investigational
Matched Description: … proteins that XL820 inhibit include platelet-derived growth factor receptor beta (PDGFR), mast/stem cell …
XL784
XL784 is a potent inhibitor of the ADAM-10 metalloprotease enzyme, a target of significant interest because of its important role in blood vessel formation and cell proliferation. XL784 was specifically optimized to be MMP-1 sparing, thus potentially enhancing its safety profile and enabling higher dosing compared with other previously studied...
Investigational
Matched Description: … enzyme, a target of significant interest because of its important role in blood vessel formation and cell …
Displaying drugs 26 - 50 of 3000 in total