Riociguat (adempas): a novel agent for the treatment of pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.
Article Details
- CitationCopy to clipboard
Khaybullina D, Patel A, Zerilli T
Riociguat (adempas): a novel agent for the treatment of pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.
P T. 2014 Nov;39(11):749-58.
- PubMed ID
- 25395817 [ View in PubMed]
- Abstract
Riociguat (Adempas): a novel agent for the treatment of pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.
DrugBank Data that Cites this Article
- Drugs
- Drug Enzymes
Drug Enzyme Kind Organism Pharmacological Action Actions Riociguat Cytochrome P450 1A1 Protein Humans NoSubstrateDetails Riociguat Cytochrome P450 2C8 Protein Humans UnknownSubstrateDetails Riociguat Cytochrome P450 2J2 Protein Humans UnknownSubstrateDetails Riociguat Cytochrome P450 3A4 Protein Humans UnknownSubstrateDetails - Drug Carriers
Drug Carrier Kind Organism Pharmacological Action Actions Riociguat Alpha-1-acid glycoprotein 1 Protein Humans UnknownSubstrateDetails Riociguat Serum albumin Protein Humans UnknownSubstrateDetails - Drug Transporters
Drug Transporter Kind Organism Pharmacological Action Actions Riociguat ATP-binding cassette sub-family G member 2 Protein Humans NoSubstrateDetails Riociguat P-glycoprotein 1 Protein Humans NoSubstrateDetails - Drug Interactions
Drugs Interaction Integrate drug-drug
interactions in your softwareRiociguatNitroglycerin Nitroglycerin may increase the hypotensive activities of Riociguat. RiociguatIsosorbide dinitrate Isosorbide dinitrate may increase the hypotensive activities of Riociguat. RiociguatIsosorbide mononitrate Isosorbide mononitrate may increase the hypotensive activities of Riociguat. RiociguatAmyl Nitrite Amyl Nitrite may increase the hypotensive activities of Riociguat. RiociguatErythrityl tetranitrate Erythrityl tetranitrate may increase the hypotensive activities of Riociguat.