Transthyretin

BE0000337ProteinHumansTTR

Thyroid hormone-binding protein. It is acted on by 62 drugs in DrugBank.

Gene name
TTR
UniProtKB entry
P02766Swiss-Prot
Cellular location
Secreted
Residues / weight
147 residues · 15,887 Da
Also known as
ATTR · PALB · Prealbumin · TBPA

Resolves to

Protein
UniProtP02766UniProt nameTTHY_HUMAN
Gene
HGNCHGNC:12405NCBI Gene7276GenBank189582GeneCardsTTR
Pharmacology
IUPHAR/GtoPdb2851KEGGhsa:7276
Structure
PDB1BM7PDB1BMZPDB1BZ8
Drugs

What you can answer from here — as of September 07, 2019

62DrugsApproved to experimental, with action, bond type and pharmacological action
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5Clinical trialsTrials of drugs acting on it, by phase and status
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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241+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Transthyretin, how selective are they, and which programs against it are still in active trials?

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