Solute carrier family 2, facilitated glucose transporter member 1

BE0001057ProteinHumansSLC2A1

Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake (PubMed:10227690, PubMed:10954735, PubMed:18245775, PubMed:19449892, PubMed:25982116, PubMed:27078104, PubMed:32860739). It is acted on by 19 drugs in DrugBank.

Gene name
SLC2A1
UniProtKB entry
P11166Swiss-Prot
Cellular location
Cell membrane
Residues / weight
492 residues · 54,083 Da
Also known as
Glucose transporter type 1, erythrocyte/brain · GLUT-1 · GLUT1 · HepG2 glucose transporter

Resolves to

Protein
UniProtP11166UniProt nameGTR1_HUMAN
Gene
HGNCHGNC:11005NCBI Gene6513GenBank183303GeneCardsSLC2A1
Pharmacology
IUPHAR/GtoPdb875KEGGhsa:6513
Structure
PDB4PYPPDB5EQGPDB5EQH
Drugs

What you can answer from here — as of September 07, 2019

19DrugsApproved to experimental, with action, bond type and pharmacological action
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8Clinical trialsTrials of drugs acting on it, by phase and status
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26GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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95+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Solute carrier family 2, facilitated glucose transporter member 1, how selective are they, and which programs against it are still in active trials?

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