STE20-like serine/threonine-protein kinase

BE0004041ProteinHumansSLK

Mediates apoptosis and actin stress fiber dissolution. It is acted on by 4 drugs in DrugBank.

Gene name
SLK
UniProtKB entry
Q9H2G2Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
1,235 residues · 142,694 Da
Also known as
2.7.11.1 · CTCL tumor antigen se20-9 · hSLK · KIAA0204 · Serine/threonine-protein kinase 2

Resolves to

Protein
UniProtQ9H2G2UniProt nameSLK_HUMAN
Gene
HGNCHGNC:11088NCBI Gene9748GenBank1944185GeneCardsSLK
Pharmacology
IUPHAR/GtoPdb2200KEGGhsa:9748
Structure
PDB2J51PDB2JFLPDB2JFM
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which approved drugs act on STE20-like serine/threonine-protein kinase, how selective are they, and which programs against it are still in active trials?

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