Antifungal Agents
- Name
- Antifungal Agents
- Accession Number
- DBCAT000200
- Description
Antibiotics inhibiting the growth of or killing fungi and used in the treatment of various fungal diseases.
- Drugs
Drug Drug Description Abafungin Investigated for use/treatment in fungal infections, bacterial infection, skin infections/disorders, and onychomycosis. Acivicin Acivicin is a small molecule drug. Acivicin has a monoisotopic molecular weight of 178.01 Da. Ajoene Not Annotated Albaconazole Albaconazole has been used in trials studying the basic science of Onychomycosis. Amorolfine A morpholine derivative commonly applied as a lacquer for onychomycosis but is also used for superficial dermatomycosis. Amphotericin B An antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis. Anidulafungin An antifungal used in the treatment of several types of candida infections. Bafilomycin A1 The bafilomycins refer to a category of toxic macrolide antibiotics that are derivatives of Streptomyces griseus. These compounds all appear in the same fermentation and have similar biological activity. Bafilomycins... Basifungin Basifungin, also known as aureuobacidin A, is a phosphorylceramide synthase inhibitor , . Benzoic acid An antimicrobial food additive. Bifonazole An azole antifungal drug used to treat fungal skin infections, such as dermatomycosis. Butenafine A topical antifungal used to treat tinea versicolor, tinea pedis, tinea cruris, and tinea corporis. Butoconazole An imidazole antifungal used to treat vulvovaginal candidiasis. Candicidin Used in the topical treatment of vulvovaginal candidiasis. Capric acid Decanoic acid is a solid. This compound belongs to the straight chain fatty acids. These are fatty acids with a straight aliphatic chain. The proteins that decanoic acid targets include... Caspofungin An echinocandin used to treat a variety of fungal infections. Cerulenin For use as a biochemical tool, Cerulenin is shown to cause dramatic weight loss in animals Chloroxine An antibacterial agent used for the treatment of dandruff and mild to moderately severe seborrheic dermatitis of the scalp. Ciclopirox A broad-spectrum topical antifungal agent used to treat mild to moderate onychomycosis of fingernails and toenails in immunocompetent patients. Cilofungin Cilofungin is a small molecule drug. The usage of the INN stem '-fungin' in the name indicates that Cilofungin is a antifungal antibiotic. Cilofungin has a monoisotopic molecular weight of... Clotrimazole A topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis. Cordycepin Cordycepin has been used in trials studying the treatment of Leukemia. Cycloheximide Cycloheximide is a small molecule drug. Cycloheximide has a monoisotopic molecular weight of 281.16 Da. Econazole A topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor. Efinaconazole An antifungal agent used to treat onychomycosis, a fungal infection of the nail. Efungumab Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel in Advanced Breast Cancer). Fenticonazole An imidazole antifungal used to treat a variety of topical fungal infections. Fluconazole A triazole antifungal used to treat various fungal infections including candidiasis. Flucytosine An antifungal indicated only to treat severe infections throughout the body caused by susceptible strains of Candida or Cryptococcus. Flutrimazole A topical antifungal used to treat pityriasis capitis and seborrheic dermatitis. Griseofulvin An antifungal agent used to treat a variety of superficial tinea infections and fungal infections of the fingernails and toes. Haloprogin Used to treat fungal (Tinea) skin infections such as athlete's foot, jock itch, ringworm, and tinea versicolor. Hexetidine An topical antiseptic agent used for disinfection and prevention of bacterial, fungal and yeast infections of the oral and vaginal mucosa. Ibrexafungerp A triterpene antifungal indicated in the treatment of vulvovaginal candidiasis and prevention of recurrent vulvovaginal candidiasis in post-menarchal patients. Icofungipen Icofungipen is a small molecule drug. Icofungipen has a monoisotopic molecular weight of 141.08 Da. Isavuconazole Indicated for patients 18 years of age and older for the treatment of invasive aspergillosis [FDA Label]. Indicated for patients 18 years of age and older for the treatment of... Isavuconazonium A triazole antifungal used for the treatment of invasive aspergillosis and mucormycosis. Isoconazole An imidazole antifungal used for superficial skin and vaginal infections. Itraconazole A triazole antifungal agent used to treat various fungal infections, such as blastomycosis and onychomycosis. Ketoconazole A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections. Lawsone Not Available Levoketoconazole One of two enantiomeric forms of racemic ketoconazole that strongly inhibits multiple steroidogenic enzymes and is used for the symptomatic treatment of endogenous Cushing's syndrome. Luliconazole A topical antifungal agent used to treat fungal infections. Mepartricin A medication indicated in the treatment of benign prostatic hyperplasia, vaginal candidiasis, or trichomoniasis. Mevastatin Not used therapeutically due to its many side effects. Micafungin An antifungal agent used for the treatment of candidemia, acute disseminated candidiasis, and certain other invasive Candida infections, and for the prophylaxis of Candida infections during stem cell transplantation. Miconazole An azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis. Miltefosine An antileishmanial agent used to treat leishmaniasis, a group of disease caused by parasites of the Leishmania type. Myxothiazol Not Available Naftifine An antifungal agent used to treat infections of the Tinea, Trichophyton, and Epidermophyton species. Natamycin A macrolide antifungal used to treat fungal infections of the eye. Nifuratel A nitrofuran derivative indicated in the treatment of leucorrhea, vulvovaginal infections, and urinary tract infections. Nikkomycin Z Nikkomycin Z has been used in trials studying the treatment and basic science of Coccidioidomycosis. Nitroxoline Nitroxoline is an antibiotic agent. Nystatin A polyene ionophore antifungal used to treat cutaneous, mucocutaneous, and gastrointestinal mycotic infections, particularly those caused by Candida species. Olorofim Olorofim is under investigation in clinical trial NCT03340597 (Assessment of Varying Oral Dosing Regimens for F901318 in Healthy Subjects). Omoconazole Not Annotated Oteseconazole An azole antifungal used to prevent recurrent vulvovaginal candidiasis in females who are not of reproductive potential. Oxiconazole A topical antifungal used to treat a variety of dermatophyte infections. Pecilocin Not Annotated Pentamidine An antifungal agent used to treat Pneumocystis pneumonia in patients infected with HIV. Pentamycin Not Annotated Posaconazole A triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients. Potassium iodate Not Annotated Pyrithione An antimicrobial agent used for the treatment of dandruff and seborrheic dermatitis. Pyroquilon Pyroquilon is a commercial blasticide which binds in the naphthol pocket of fungal trihydroxynaphthalene reductase active site. Pyrrolnitrin Not Annotated Radicicol Not Available Ravuconazole Investigated for use/treatment in fungal infections, aspergillosis, candidiasis, and onychomycosis. Rezafungin An echinocandin antifungal indicated in patients over 18 years old who have limited or no alternative options for the treatment of candidemia and invasive candidiasis. Rutamycin Rutamycin is a small molecule drug. The usage of the INN stem '-mycin' in the name indicates that Rutamycin is a antibiotic, produced by Streptomyces strain. Rutamycin has a monoisotopic... Salicylhydroxamic Acid Not Available Salicylic acid An acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. Sertaconazole A topical antifungal agent used in the treatment of interdigital tinea pedis in immunocompetent patients. Sinefungin Sinefungin is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar. The proteins that adenosyl-ornithine target include... Sirolimus An mTOR inhibitor immunosuppressant used to prevent organ transplant rejections, treat lymphangioleiomyomatosis, and treat adults with perivascular epithelioid cell tumors. Sulconazole A topical antifungal agent used for the treatment of tinea cruris, tinea corporis, and tinea versicolor caused by susceptible fungal strains. Tavaborole An antifungal agent used to treat onychomycosis, a fungal infection of the nail. Terbinafine An allylamine antifungal used to treat dermatophyte infections of toenails and fingernails as well as other fungal skin infections. Terconazole An antifungal drug used in the treatment of vulvovaginal candidiasis. Thymol An essential oil found in various over-the-counter antibacterial and antifungal products. Tioconazole An imidazole antifungal used to treat vulvovaginal candidiasis. Tolciclate Not Annotated Tolnaftate An antifungal agent used to treat various skin infections caused by fungi. Triacetin An acetylating agent indicated in the treatment of ringworm. Trichostatin A Not Available Troclosene Not Annotated VL-2397 Not Annotated Voriconazole A triazole compound used to treat fungal infections. Wortmannin Wortmannin is a steroid metabolite of Penicillium funiculosum and Talaromyces wortmannii fungi. This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks). - Drugs & Drug Targets