Quaternary Ammonium Compounds
- Quaternary Ammonium Compounds
- Accession Number
Derivatives of ammonium compounds, NH4+ Y-, in which all four of the hydrogens bonded to nitrogen have been replaced with hydrocarbyl groups. These are distinguished from IMINES which are RN=CR2.
- ATC Classification
Drug Drug Description Decamethoxine Not Annotated Cetrimonium A compound that can be used as a topical antiseptic. Choline A nutrient found in a wide variety of vitamins including pre-natal formulations. Succinylcholine A depolarizing skeletal muscle relaxant used adjunctly to anesthesia and for skeletal muscle relaxation during intubation, mechanical ventilation, and surgical procedures. Oxyphenonium For the treatment of visceral spasms Carbamoylcholine A direct acting miotic agent administered ophthalmically to decrease intraocular pressure after cataract surgery, and to induce miosis during surgery. Gallamine triethiodide A nondepolarizing nerve blocker used in addition to anesthesia to cause skeletal muscle relaxation. Glycopyrronium An anticholinergic agent used to treat hyperhidrosis, severe drooling, COPD, used with other medications to treat ulcers, and used in anesthesia. Bethanechol A muscarinic agonist used to treat postoperative and postpartum nonobstructive functional urinary retention and neurogenic atony of the bladder with retention. Ambenonium A cholinesterase inhibitor that targets both muscarinic and nicotinic receptors indicated for the treatment of myasthenia gravis. Methacholine A parasympathomimetic bronchoconstrictor used to diagnose bronchial hyperreactivity in subjects who do not have clinically apparent asthma. Betaine A methyl group donor used for the treatment of homocystinuria to decrease elevated homocysteine blood levels. Benzalkonium An antiseptic agent used as a preservative in medications or as a disinfectant in cleaning products. Benzethonium A medication used as to clean hands and clean minor cuts and scrapes. Emepronium Not Annotated Benzoxonium An antiseptic indicated in skin disinfection and prevention of infections. Gallamine Not Annotated Cetylpyridinium A compound used to reduce plaque and gingivitis, as well as whiten teeth. Octenidine An antiseptic agent used topically, on mucous membranes, and prior to surgery. Didecyldimethylammonium A disinfectant and microbicidal agent used in a variety of products. Methantheline For the treatment of peptic ulcer disease, irritable bowel syndrome, pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, and reflex neurogenic bladder in children. Propantheline An antimuscarinic agent used to treat urinary incontinence, hyperhidrosis, as well as cramps and spasms of the stomach, intestines, and bladder. Edrophonium A cholinesterase inhibitor used to diagnose and evaluate myasthenia gravis. Tubocurarine Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to... Neostigmine A cholinesterase inhibitor used in the symptomatic treatment of myasthenia gravis by improving muscle tone. Butylscopolamine An antispasmodic and anticholinergic agent used for the symptomatic treatment of abdominal cramping and pain. Alcuronium A non-depolarizing skeletal muscle relaxant similar to tubocurarine. It is used as an anesthesia adjuvant. Metocurine iodide For use as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy. Levocarnitine A quaternary ammonium compound used to treat carnitine deficiency or to stimulate gastric and pancreatic secretions in hyperlipoproteinemia. Hexafluronium Used as an adjunct with succinylcholine (or suxamethonium chloride) to prolong muscle relaxation and to prevent succinylcholine-induced muscle fasciculations. Bretylium A norepinephrine release inhibitor used for the prophylaxis and therapy of ventricular fibrillation, as well as the treatment of life-threatening ventricular arrhythmias. Decamethonium For use as a skeletal muscle relaxant Oxtriphylline A bronchodilator used for the treatment of asthma, bronchitis, COPD, and emphysema. Metocurine Metocurine is a muscle relaxant. Choline magnesium trisalicylate Choline magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults. Platelet Activating Factor Not Available N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction. Butyrylthiocholine A sulfur-containing analog of butyrylcholine which is hydrolyzed by butyrylcholinesterase to butyrate and thiocholine. It is used as a reagent in the determination of butyrylcholinesterase activity. [PubChem] Betaine aldehyde Not Available C31G Investigated for use/treatment in contraception, HIV infection, and prevention of stdis. Perifosine Investigated for use/treatment in solid tumors, multiple myeloma, leukemia (unspecified), lung cancer, and brain cancer. Lauryldimethylbetaine Not Available Tetraethylammonium Tetraethylammonium is an experimental drug with no approved indication. Acetylcarnitine An acetylated form of the amino acid derivative L-carnitine that assists in mitochondrial fatty acid metabolism. It is under investigation as a treatment for numerous conditions, including neuropathy, depression, and dementia. Hexamethonium A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been... Miltefosine An antileishmanial agent used to treat leishmaniasis, a group of disease caused by parasites of the Leishmania type. Light green SF yellowish Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining solution which is widely used as a counterstain. It is used in... Cocamidopropyl betaine Cocamidopropyl betaine is a mixture of closely related organic compounds derived from coconut oil and dimethylaminopropylamine that typically acts as an amphoteric surfactant in cosmetics and personal care products. It... Citicoline An endogenous intermediate in the formation of phosphatidylcholine from choline which is thought to have neuroprotective effects. Benzododecinium Benzododecinium is used as an antiseptic/disinfectant compound. It has been marketed as a tincture for antiseptic product for wounds in the Czech Republic. Choline salicylate The oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due... Cetyltrimethylammonium naproxenate An anti-inflammatory and antiseptic agent indicated to treat mouth inflammation and pain , including that caused by tooth extraction. Fluorocholine F-18 A radiopharmaceutical indicated in PET scans of the prostate.
- Drugs & Drug Targets