Accession Number

Organic chemicals which have two amino groups in an aliphatic chain.

DrugDrug Description
SpermineFor nutritional supplementation, also for treating dietary shortage or imbalance
EthambutolAn antituberculosis agent used in the prophylaxis and treatment of tuberculosis (TB).
TripelennamineA histamine H1 antagonist used to treat hypersensitivity reactions, coughs, and the common cold.
Edetic acidA chelating agent used to treat mercury and lead toxicity and some blood transfusion dependent anemias.
AminophyllineA bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.
PutrescinePutrescine is a toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine. Putrescine is a solid. This compound belongs to the polyamines. These are compounds containing more...
4,5-Dimethyl-1,2-phenylenediamineNot Available
GlutathionylspermidineNot Available
TrypanothioneNot Available
SpermidineSpermidine is a polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and...
MethapyrileneMethapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.
EzogabineAn antiepileptic agent used as an adjuvant treatment of partial-onset seizures.
SQ-109Investigated for use/treatment in bacterial infection, infectious and parasitic disease (unspecified), and tuberculosis.
DP-b99Investigated for use/treatment in strokes and traumatic brain injuries.
TrodusquemineInvestigated for use/treatment in obesity and diabetes mellitus type 2.
DiethylnorspermineInvestigated for use/treatment in renal cell carcinoma, pancreatic cancer, melanoma, and lung cancer.
MangafodipirAn organ-specific paramagnetic contrast agent indicated for the imaging of the hepatobiliary system and detecting lesions in the liver and pancreas.
TriethylenetetramineA copper chelating agent used for the management of Wilson's disease in cases where penicillamine therapy is clinically inappropriate.
ChloropyramineFor the treatment of allergic conjunctivitis, allergic rhinitis, bronchial asthma, and other atopic (allergic) conditions.
Sodium feredetateNot Annotated
TenitramineNot Annotated
p-PhenylenediamineNot Annotated
EthylenediamineEthylenediamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years...
N,N'-diphenyl-1,4-phenylenediamineNot Annotated
4-(Isopropylamino)diphenylamine4-(Isopropylamino)diphenylamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years...
N-Cyclohexyl-N'-phenyl-1,4-phenylenediamineN-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years...
CadaverineCadaverine is a foul-smelling diamine formed by bacterial decarboxylation of lysine.
MDL72527Not Available
Gallium Ga-68 gozetotideA radiopharmaceutical agent used in the diagnosis of prostate-specific membrane antigen (PSMA) positive lesions in male patients during positron emission tomography.
ChiauranibChiauranib is under investigation in clinical trial NCT03974243 (Chiauranib in Combination With Chidamide in Patients With Relapsed/refractory Non-hodgkin's Lymphoma).
AcetyldinalineAcetyldinaline is under investigation in clinical trial NCT00005624 (CI-994 in Treating Patients With Advanced Myeloma).
CGC-11047Investigated for use/treatment in lymphoma (unspecified), macular degeneration, prostate cancer, and solid tumors.
Drugs & Drug Targets
SpermineSpermine oxidasetarget
SpermineSpermine synthasetarget
SpermineOrnithine decarboxylasetarget
SpermineXanthine dehydrogenase/oxidaseenzyme
SpermineSolute carrier family 22 member 4transporter
SpermineSolute carrier family 22 member 1transporter
SpermineDiamine acetyltransferase 1enzyme
SpermineDiamine acetyltransferase 2enzyme
SpermineExtracellular calcium-sensing receptortarget
SpermineBeta-1 adrenergic receptortarget
SpermineBeta-2 adrenergic receptortarget
EthambutolProbable arabinosyltransferase Btarget
EthambutolProbable arabinosyltransferase Atarget
EthambutolProbable arabinosyltransferase Ctarget
EthambutolCytochrome P450 1A2enzyme
EthambutolCytochrome P450 2E1enzyme
EthambutolCytochrome P450 2C19enzyme
EthambutolCytochrome P450 2D6enzyme
EthambutolCytochrome P450 2A6enzyme
EthambutolCytochrome P450 2C9enzyme
EthambutolCytochrome P450 3A4enzyme
TripelennamineHistamine H1 receptortarget
TripelennamineCytochrome P450 2D6enzyme
Edetic acidLeadtarget
Edetic acidIrontarget
Edetic acidManganese cationtarget
Edetic acidAdenosine deaminaseenzyme
Edetic acidSerum paraoxonase/lactonase 3enzyme
Edetic acidCytochrome P450 19A1enzyme
AminophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
AminophyllineAdenosine receptor A3target
AminophyllineAdenosine receptor A1target
AminophyllineCytochrome P450 1A2enzyme
AminophyllineCytochrome P450 2E1enzyme
AminophyllineCytochrome P450 3A4enzyme
AminophyllineHistone deacetylase 2target
PutrescineOrnithine decarboxylasetarget
PutrescineS-adenosylmethionine decarboxylase proenzymetarget
PutrescinePutrescine-binding periplasmic proteintarget
PutrescineSolute carrier family 22 member 4transporter
PutrescineBeta-1 adrenergic receptortarget
PutrescineBeta-2 adrenergic receptortarget
4,5-Dimethyl-1,2-phenylenediamineNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferasetarget
TrypanothioneTrypanothione reductasetarget
SpermidineThioredoxin reductase 1, cytoplasmictarget
SpermidineGentamicin 3'-acetyltransferasetarget
SpermidineSpermidine/putrescine-binding periplasmic proteintarget
SpermidineSolute carrier family 22 member 4transporter
SpermidineSolute carrier family 22 member 1transporter
SpermidineBeta-1 adrenergic receptortarget
SpermidineBeta-2 adrenergic receptortarget
EzogabinePotassium voltage-gated channel subfamily KQT member 2target
EzogabinePotassium voltage-gated channel subfamily KQT member 3target
EzogabinePotassium voltage-gated channel subfamily KQT member 4target
EzogabinePotassium voltage-gated channel subfamily KQT member 5target
EzogabineUDP-glucuronosyltransferase 1-1enzyme
EzogabineUDP-glucuronosyltransferase 1-3enzyme
EzogabineUDP-glucuronosyltransferase 1-4enzyme
EzogabineUDP-glucuronosyltransferase 1-9enzyme
EzogabineArylamine N-acetyltransferase 2enzyme
TrodusquemineTyrosine-protein phosphatase non-receptor type 1target
TrodusquemineSodium-dependent dopamine transportertarget
TrodusquemineSodium-dependent noradrenaline transportertarget
MangafodipirSerum albumincarrier
MangafodipirSuperoxide dismutase [Mn], mitochondrialenzyme
MangafodipirNatural resistance-associated macrophage protein 2transporter
ChloropyramineHistamine H1 receptortarget
Cadaverine2-C-methyl-D-erythritol 4-phosphate cytidylyltransferasetarget
MDL72527Spermine oxidasetarget
Gallium Ga-68 gozetotideProstate-specific antigentarget