Name
Diamines
Accession Number
DBCAT000286
Description

Organic chemicals which have two amino groups in an aliphatic chain.

Drugs
DrugDrug Description
EthambutolAn antituberculosis agent used in the prophylaxis and treatment of tuberculosis (TB).
TripelennamineA histamine H1 antagonist used to treat hypersensitivity reactions, coughs, and the common cold.
CadaverineCadaverine is a foul-smelling diamine formed by bacterial decarboxylation of lysine.
AminophyllineA bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.
PutrescinePutrescine is a toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine. Putrescine is a solid. This compound belongs to the polyamines. These are compounds containing more...
SQ-109Investigated for use/treatment in bacterial infection, infectious and parasitic disease (unspecified), and tuberculosis.
ChloropyramineFor the treatment of allergic conjunctivitis, allergic rhinitis, bronchial asthma, and other atopic (allergic) conditions.
TenitramineNot Annotated
EthylenediamineEthylenediamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years...
Edetic acidA chelating agent used to treat mercury and lead toxicity and some blood transfusion dependent anemias.
4,5-Dimethyl-1,2-phenylenediamineNot Available
MDL72527Not Available
MethapyrileneMethapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.
EzogabineAn antiepileptic agent used as an adjuvant treatment of partial-onset seizures.
DP-b99Investigated for use/treatment in strokes and traumatic brain injuries.
MangafodipirAn organ-specific paramagnetic contrast agent indicated for the imaging of the hepatobiliary system and detecting lesions in the liver and pancreas.
TriethylenetetramineA copper chelating agent used for the management of Wilson's disease in cases where penicillamine therapy is clinically inappropriate.
TacedinalineTacedinaline has been used in trials studying the treatment of Lung Cancer, Multiple Myeloma, and Pancreatic Cancer.
Sodium feredetateNot Annotated
p-PhenylenediamineNot Annotated
N,N'-diphenyl-1,4-phenylenediamineNot Annotated
4-(Isopropylamino)diphenylamine4-(Isopropylamino)diphenylamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years...
N-Cyclohexyl-N'-phenyl-1,4-phenylenediamineN-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years...
Edetate calcium disodium anhydrousA chelating agent used to treat lead poisoning.
AcetyldinalineAcetyldinaline is under investigation in clinical trial NCT00005624 (CI-994 in Treating Patients With Advanced Myeloma).
Drugs & Drug Targets
DrugTargetType
EthambutolProbable arabinosyltransferase Btarget
EthambutolProbable arabinosyltransferase Atarget
EthambutolProbable arabinosyltransferase Ctarget
EthambutolCytochrome P450 1A2enzyme
EthambutolCytochrome P450 2E1enzyme
EthambutolCytochrome P450 2C19enzyme
EthambutolCytochrome P450 2D6enzyme
EthambutolCytochrome P450 2A6enzyme
EthambutolCytochrome P450 2C9enzyme
EthambutolCytochrome P450 3A4enzyme
TripelennamineHistamine H1 receptortarget
TripelennamineCytochrome P450 2D6enzyme
TripelennamineSerum albumincarrier
Cadaverine2-C-methyl-D-erythritol 4-phosphate cytidylyltransferasetarget
AminophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
AminophyllineAdenosine receptor A3target
AminophyllineAdenosine receptor A1target
AminophyllineCytochrome P450 1A2enzyme
AminophyllineCytochrome P450 2E1enzyme
AminophyllineCytochrome P450 3A4enzyme
AminophyllineHistone deacetylase 2target
PutrescineOrnithine decarboxylasetarget
PutrescineS-adenosylmethionine decarboxylase proenzymetarget
PutrescinePutrescine-binding periplasmic proteintarget
PutrescineSolute carrier family 22 member 4transporter
PutrescineBeta-1 adrenergic receptortarget
PutrescineBeta-2 adrenergic receptortarget
ChloropyramineHistamine H1 receptortarget
Edetic acidLeadtarget
Edetic acidIrontarget
Edetic acidManganese cationtarget
Edetic acidAdenosine deaminaseenzyme
Edetic acidSerum paraoxonase/lactonase 3enzyme
Edetic acidCytochrome P450 19A1enzyme
4,5-Dimethyl-1,2-phenylenediamineNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferasetarget
MDL72527Spermine oxidasetarget
EzogabinePotassium voltage-gated channel subfamily KQT member 2target
EzogabinePotassium voltage-gated channel subfamily KQT member 3target
EzogabinePotassium voltage-gated channel subfamily KQT member 4target
EzogabinePotassium voltage-gated channel subfamily KQT member 5target
EzogabineUDP-glucuronosyltransferase 1-1enzyme
EzogabineUDP-glucuronosyltransferase 1-3enzyme
EzogabineUDP-glucuronosyltransferase 1-4enzyme
EzogabineUDP-glucuronosyltransferase 1-9enzyme
EzogabineArylamine N-acetyltransferase 2enzyme
MangafodipirAlpha-2-macroglobulincarrier
MangafodipirSerum albumincarrier
MangafodipirSuperoxide dismutase [Mn], mitochondrialenzyme
MangafodipirNatural resistance-associated macrophage protein 2transporter
TriethylenetetramineGlypican-1transporter
Edetate calcium disodium anhydrousManganese cationtarget
Edetate calcium disodium anhydrousIrontarget
Edetate calcium disodium anhydrousLeadtarget
Edetate calcium disodium anhydrousAdenosine deaminaseenzyme
Edetate calcium disodium anhydrousSerum paraoxonase/lactonase 3enzyme
Edetate calcium disodium anhydrousCytochrome P450 19A1enzyme
Edetate calcium disodium anhydrousCytochrome P450 3A4enzyme
Edetate calcium disodium anhydrousSerum paraoxonase/arylesterase 1enzyme