Dietary Fats

Name
Dietary Fats
Accession Number
DBCAT000296
Description

Fats present in food, especially in animal products such as meat, meat products, butter, ghee. They are present in lower amounts in nuts, seeds, and avocados.

Drugs
DrugDrug Description
Omega-3-acid ethyl estersA mixture of fatty acids used as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe hypertriglyceridemia.
alpha-Linolenic acidA polyunsaturated omega-3 fatty acid found in many supplements.
IcosapentA polyunsaturated fatty acid, usually found in fish oils, that is used in many supplements.
DoconexentAn omega 3 fatty acid used in a variety of nutritional supplements to support central nervous system and cardiovascular health.
Icosapent ethylAn ethyl ester of eicosapentaenoic acid (EPA) that reduces synthesis and enhances clearance of triglycerides that is used to treat patients with severe hypertriglyceridemia.
Soybean oilAn oil used as a source of calories and essential fatty acids in selected patients for total parenteral nutrition (TPN) therapy and prevention of essential fatty acid deficiency.
Safflower oilNo approved therapeutic indications.
Olive oilIn a clinical context, olive oil is used as a source of calories and fatty acids in patients requiring parenteral nutrition. A formulation called Clinolipid, comprising olive oil and soybean...
Omega-3 fatty acidsAn ingredient found in a variety of supplements and vitamins.
Sesame oilSesame oil is a commonly used vegetable oil in Asia and flavoring enhancer in various culinary practices. It is extracted from sesame seeds and contains linoleic acid, oleic acid, palmitic...
Cod liver oilAn ingredient found in a variety of nutritional products.
Resolvin E1Resolvin E1 (RX 10001) is under investigation in clinical trial NCT00941018 (Single and Multiple Ascending Oral Dose Study of Resolvin E1 in Healthy Volunteers).
TP-252TP-252 consists of magnesium L-lysinate bis-eicosapentaenoate, an ionizable salt of eicosapentaenoic acid (EPA), currently being investigated to treat familial adenomatous polyposis.
EpeleutonNot Annotated
AP-001Not Annotated
Rice bran oilRice bran oil is extracted from the hard outer brown layer of rice after chaff (rice husk) used for high-temperature cooking methods such as deep frying and stir frying. It...
Peanut oilA compound used to lubricate ear wax, as an emollient, and used in laxatives.
Coconut oilCoconut oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
AVX-001AVX-001 is under investigation in clinical trial NCT05164393 (Phase I/iia Trial to Evaluate AVX001 Gel in Doses of 1% or 3% Compared With Vehicle Over Four Weeks of Field-directed Treatment...
Drugs & Drug Targets
DrugTargetType
Omega-3-acid ethyl estersSterol O-acyltransferase 1enzyme
Omega-3-acid ethyl estersSterol regulatory element-binding protein 1target
alpha-Linolenic acidFatty acid-binding protein, braincarrier
alpha-Linolenic acidAcyl-CoA (8-3)-desaturasetarget
alpha-Linolenic acidAcyl-CoA 6-desaturasetarget
alpha-Linolenic acidSodium/calcium exchanger 1target
alpha-Linolenic acidTransient receptor potential cation channel subfamily V member 1target
alpha-Linolenic acidPeroxisome proliferator-activated receptor alphatarget
alpha-Linolenic acidBile acid receptortarget
alpha-Linolenic acidPeroxisome proliferator-activated receptor deltatarget
alpha-Linolenic acidPeroxisome proliferator-activated receptor gammatarget
alpha-Linolenic acidRetinoic acid receptor RXR-alphatarget
alpha-Linolenic acidVery long chain fatty acid elongase 2target
alpha-Linolenic acidVery long chain fatty acid elongase 5target
alpha-Linolenic acidFree fatty acid receptor 1target
alpha-Linolenic acidProstaglandin G/H synthase 2target
IcosapentProstaglandin G/H synthase 2target
IcosapentProstaglandin G/H synthase 1target
IcosapentFree fatty acid receptor 1target
IcosapentAcyl-CoA (8-3)-desaturasetarget
IcosapentLong-chain-fatty-acid--CoA ligase 4target
IcosapentSodium/calcium exchanger 1target
IcosapentPeroxisome proliferator-activated receptor gammatarget
IcosapentPeroxisome proliferator-activated receptor deltatarget
IcosapentTransient receptor potential cation channel subfamily V member 1target
IcosapentPeroxisome proliferator-activated receptor alphatarget
IcosapentAlbumincarrier
IcosapentFatty acid-binding protein, braintarget
IcosapentPolyunsaturated fatty acid 5-lipoxygenasetarget
DoconexentCytochrome P450 2C9enzyme
DoconexentPeroxisome proliferator-activated receptor alphatarget
DoconexentPeroxisome proliferator-activated receptor gammatarget
DoconexentSterol regulatory element-binding protein 1target
DoconexentRetinoic acid receptor RXR-alphatarget
DoconexentRetinoic acid receptor RXR-betatarget
DoconexentRetinoic acid receptor RXR-gammatarget
DoconexentMyc proto-oncogene proteintarget
DoconexentProstaglandin G/H synthase 2target
DoconexentProstaglandin G/H synthase 1target
Soybean oilPeroxisome proliferator-activated receptor alphatarget
Omega-3 fatty acidsPeroxisome proliferator-activated receptor gammatarget
Omega-3 fatty acidsProstaglandin G/H synthase 2enzyme
Omega-3 fatty acidsPolyunsaturated fatty acid 5-lipoxygenaseenzyme
Omega-3 fatty acidsPeroxisome proliferator-activated receptor alphatarget
Omega-3 fatty acidsSterol regulatory element-binding protein 1target