- Accession Number
Chemical compounds which yield hydrogen ions or protons when dissolved in water, whose hydrogen can be replaced by metals or basic radicals, or which react with bases to form salts and water (neutralization). An extension of the term includes substances dissolved in media other than water. (Grant & Hackh's Chemical Dictionary, 5th ed)
Drug Drug Description Cystine An oxidated derivative of the amino acid cysteine found in various nutritional products and creams to treat cervical injury or inflammation. Bortezomib A proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies. Calcium acetate A phosphate binder used in patients with end-stage renal disease (ESRD) to prevent elevated phosphate levels and resulting ectopic calcification and secondary hyperparathyroidism. Nitroprusside A direct acting vasodilator used to treat hypertension, to induce controlled hypotension to reduce postoperative bleeding, and to manage acute heart failure. Sodium tetradecyl sulfate An anionic surfactant used to treat varicose veins of the lower extremities. Fosinopril An ACE inhibitor used to treat mild to moderate hypertension, congestive heart failure, and to slow the progression of renal disease in hypertensive diabetics. Bentoquatam Used to prevent or reduce the severity of allergic contact dermatitis due to urushiol, the allergenic resin of poison ivy, poison oak, and poison sumac. Cyclophosphamide A nitrogen mustard used to treat lymphomas, myelomas, leukemia, mycosis fungoides, neuroblastoma, ovarian adenocarcinoma, retinoblastoma, and breast carcinoma. Magnesium sulfate A drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany. Acamprosate A medication used to maintain alcohol abstinence in patients with alcohol dependence. Pentosan polysulfate A sulfated pentosyl polysaccharide used to treat bladder pain and discomfort due to interstitial cystitis. Potassium chloride A potassium salt used to treat hypokalemia. Sodium lauryl sulfate An anionic surfactant used in cosmetics and pharmaceuticals as a fat emulsifier, wetting agent, and detergent. Disulfiram A carbamate derivative used to treat alcohol addiction. Busulfan An alkylating agent used to treat chronic myelogenous leukemia. Calcium chloride An ionic compound used for the treatment of hypocalcemia and hyperkalemia, and as an antidote to magnesium intoxication due to overdosage of magnesium sulfate. Ifosfamide An alkylating and immunosuppressive agent used in chemotherapy for the treatment of cancers, including testicular cancer, ovarian cancer, cervical cancer, osteocarcinoma, bladder cancer, small cell lung cancer, and non-Hodgkin's lymphoma. Sodium bicarbonate A compound used for the symptomatic treatment of heartburn, acid indigestion, and upset stomach as well as the treatment of metabolic acidosis associated with conditions such as severe renal disease and circulatory insufficiency due to shock. Kaolin A natural ingredient used for the short-term symptomatic treatment of various conditions including diarrhea, skin dryness, and minor skin bleeding. Amyl Nitrite A fast acting vasodilator used for rapid relief of angina pectoris. Erythrityl tetranitrate For the prevention of angina. Phenylethane Boronic Acid Not Available Thiopyrophosphate Not Available 2-Hydroxyethyl Disulfide Not Available Geranyl Diphosphate Not Available Cyanamide A cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The... 3-Nitrophenylboronic Acid Not Available Methylphosphinic Acid Not Available p-Toluenesulfonic acid Not Available 3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid Not Available Perchlorate Not Available N-cyclohexyltaurine Not Available Ethanesulfonic acid Not Available Tribenuron Methyl Not Available Ethyl dihydrogen phosphate Not Available Dodecyl sulfate Not Available Pyrophosphoric acid An ingredient of a radiopharmaceutical used to visualize bone abnormalities and cardiovascular abnormalities and also used as an ingredient in some products to prevent iron deficiency anemia. Taurocholic acid The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats... Latamoxef Latamoxef is an oxacephem antibiotic usually grouped with the cephalosporins. It is used to treat bacterial infections. Latamoxef is primarily indicated in conditions like Bone and joint infection, GI infections,... Thiotepa An alkylating agent used to prevent graft rejection in stem cell transplantation and to treat a variety of malignancies including certain types of adenocarcinoma and superficial bladder carcinomas. Naphthalene-2,6-disulfonic acid Not Available Suramin For treatment of human sleeping sickness, onchocerciasis and other diseases caused by trypanosomes and worms. OXI-4503 Investigated for use/treatment in cancer/tumors (unspecified). Chlorfenson Investigated for use/treatment in fungal infections. PRO 2000 Investigated for use/treatment in HIV prevention, prevention of stdis, and vaginal infection. AZD 3355 Investigated for use/treatment in gastroesophageal reflux disease (GERD). NCX 701 Investigated for use/treatment in pain (acute or chronic). Palifosfamide Investigated for use/treatment in cancer/tumors (unspecified), lymphoma (unspecified), and sarcoma. Flovagatran Investigated for use/treatment in thrombosis. Evofosfamide Investigated for use/treatment in solid tumors. Fosdevirine Investigated for use/treatment in HIV infection and acquired immune deficiency syndrome (AIDS) and aids-related infections. Glufosfamide Investigated for use/treatment in pancreatic cancer, solid tumors, breast cancer, colorectal cancer, brain cancer, lung cancer, ovarian cancer, and sarcoma. Talabostat Investigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), lung cancer, melanoma, and pancreatic cancer. Caldaret Investigated for use/treatment in heart disease and myocardial infarction. Avasimibe Investigated for use/treatment in peripheral vascular disease. Tramiprosate Investigated for use/treatment in strokes and alzheimer's disease. Tesaglitazar Investigated for use/treatment in diabetes mellitus type 2. N-chlorotaurine Investigated for use/treatment in eye disorders/infections. Aluminum hydroxide An antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach. Calcium carbonate An ionic compound used as a calcium supplement or antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach. Manganese A transition metal used for supplementation of manganese during Total Parenteral Nutrition (TPN). Ammonium chloride Expectorant in cough syrups. The ammonium ion (NH4+) in the body plays an important role in the maintenance of acid-base balance. The kidney uses ammonium (NH4+) in place of sodium... Cupric sulfate A compound used as an intravenous copper supplement for Total Parenteral Nutrition (TPN). Prussian blue A chelating agent used to reduce the extent of systemic contamination with radioactive cesium and/or radioactive or non-radioactive thallium. 4,4'-DIPYRIDYL DISULFIDE Not Available 2-Naphthalenesulfonic acid Not Available Taurochenodeoxycholic acid Taurochenodeoxycholic acid is likely indicated as a choleretic and cholagogue. It is also being investigated for its role in inflammation and cancer therapy. Tauroursodeoxycholic acid Used in the treatment of cholesterol gallstones. Tauroursodeoxycholic acid is also being investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis,... Potassium alum Potassium alum is considered safe by the FDA and its use is in homepathic or OTC products. Due to its presence in several different drugs, the main indications for the... Coenzyme M A uroprotective agent used for the reduction and prophylaxis of oxazaphosphorine-induced toxicity in the urinary tract. Nitrous acid An iron binder used to reverse life-threatening acute cyanide poisoning. Chromic chloride A supplement to intravenous solutions given for total parenteral nutrition (TPN). Ferric pyrophosphate Ferric pyrophosphate is intended to be indicated for the treatment of iron loss or iron deficiency as a formulation with a milder gastrointestinal effect.[L1423, L1433] Iron deficiency appears when the... Sodium chloride An ingredient found in a variety of nutritional products as a source of electrolytes and water. Trypan blue free acid A dye used as a visualizing aid to stain the epiretinal membranes during ophthalmic surgical vitrectomy procedures, thereby facilitating removal of the tissue. Technetium Tc-99m pyrophosphate A radiopharmaceutical diagnostic agent used for diagnostic imaging scans for the bones, heart, and gastrointestinal tract. Nicorandil Indicated for the prevention and treatment of chronic stable angina pectoris and reduction in the risk of acute coronary syndromes. Magnesium trisilicate An antacid used for the symptomatic treatment of peptic ulcers. Zinc sulfate A drug used to replenish low levels of zinc or prevent zinc deficiency, or to test for zinc deficiency. Phosphoric acid An ingredient used for electrolyte replenishment and total parenteral nutrition (TPN) therapy, and for the relief of upset stomach associated with nausea. Magnesium chloride An ionic compound and source of magnesium used for electrolyte replenishment and conditions associated with magnesium deficiencies. Monopotassium phosphate An ionic compound used for electrolyte replenishment and total parenteral nutrition (TPN) therapy. Dipotassium phosphate An ionic compound used for electrolyte replenishment and total parenteral nutrition (TPN) therapy. Potassium perchlorate No current FDA- or EMA-approved therapeutic indications. Technetium Tc-99m polyphosphate Not Annotated Sodium phosphate, monobasic A source of phosphorus used prevent or correct hypophosphatemia in patients with restricted or no oral intake. Sodium carbonate Used topically for dermatitides, mouthwash, vaginal douche; veterinary use as emergency emetic.Occasionally, for dermatitides topically as a lotion. Medication (Vet): In solution to cleanse skin, in eczema, to soften scabs... Sodium sulfate An agent used for bowel cleansing prior to colonoscopy or barium enema X-ray examination. Sodium fluorophosphate A fluoride anticaries agent used to prevent and treat dental cavities. Thiosulfuric acid A sulfur donor used for sequential use with sodium nitrite for the reversal of acute cyanide poisoning that is judged to be life-threatening. Talc A mineral used to prevent recurrence of malignant pleural effusions in symptomatic patients during thoracoscopy or open thoracotomy. Ecamsule A sunscreen agent found in sunscreens that absorbs UV rays. Hydrogen fluoride A compound used in dentistry to prevent dental caries. Silver nitrate Silver nitrate is an inorganic compound with the chemical formula AgNO3. In its solid form, silver nitrate is coordinated in a trigonal planar arrangement. It is often used as a... Aluminum chloride Indicated for the control of minor hemorrhage during dental restorative procedures. Indicated to reduce underarm perspiration. Potassium nitrate A medication used to cauterize small wounds, remove granulation tissue, warts, and verrucae, and treat tooth sensitivity. Potassium bicarbonate An ingredient used as an antacid or to treat hypokalemia. Sulfur hexafluoride A medication used in ultrasound to enhance viewing of blood vessels and the urinary tract. Aluminum sesquichlorohydrate An antiperspirant used to reduce sweating. Ensulizole An ingredient used in sunscreens to absorb UVB radiation. Hypochlorite An antimicrobial used to treat and prevent infections of the skin and tissue. Silicon dioxide An ingredient found in a variety of supplements and vitamins. Barium sulfate A contrast agent used for CT scans of the gastrointestinal tract. Sodium sulfide Sodium sulfide is a chemical compound with a chemical formula Na2S. Sodium sulfide is used in the pulp and paper industry, water treatment, textile industry, and various chemical manufacturing processes... Light green SF yellowish Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining solution which is widely used as a counterstain. It is used in... Calcium sulfide Not Annotated Magnesium Aluminum Silicate Magnesium aluminum silicate is used as an over the counter antacid for the self-treatment of heartburn, sour stomach, or acid indigestion [FDA Label]. Aluminum sulfate A medication used to prevent infections and to treat minor bleeding. Bentonite Not Annotated Sulfuric acid Not Annotated Boric acid No FDA- or EMA-approved therapeutic indications on its own. Calcium Phosphate A compound used in supplements and antacids. Sodium tripolyphosphate Sodium tripolyphosphate is an inorganic compound with formula Na5P3O10 and the sodium salt of the polyphosphate penta-anion. It is used as a component of a wide range domestic and industrial... PF-4191834 PF-4191834 has been investigated for the basic science of Asthma. Indium Indium has been used in trials studying the basic science of Clear Cell Renal Cell Carcinoma. Treosulfan Treosulfan is under investigation in Allogeneic Haematopoietic Stem Cell Transplantation. Treosulfan has been investigated for the treatment of Lymphoblastic Leukemia, Acute, Childhood. Allicin Allicin has been used in trials studying the treatment of Follicular Lymphoma. Lesogaberan Lesogaberan has been used in trials studying the treatment and basic science of GERD, Reflux, Heartburn, Regurgitation, and Reflux Disease, among others. Lodenafil carbonate Lodenafil carbonate has been used in trials studying the treatment of Coronaropathy and Erectile Dysfunction. Delanzomib Delanzomib has been used in trials studying the treatment of Solid Tumors, Multiple Myeloma, and Lymphoma, Non-Hodgkin. Mafosfamide Mafosfamide has been used in trials studying the treatment of Lymphoma, Leukemia, Meningeal Neoplasm, and Brain and Central Nervous System Tumors. Vaborbactam A beta lactamase inhibitor used to treat complicated urinary tract infections. CPI-613 CPI-613 has been used in trials studying the treatment of Cancer, Lymphoma, Solid Tumors, Advanced Cancer, and Pancreatic Cancer, among others. Auriclosene Auriclosene has been used in trials studying the treatment of Impetigo, Bacterial Conjunctivitis, Asymptomatic Bacteriuria, and Adenoviral Conjunctivitis. GW-274150 GW274150 has been used in trials studying the treatment and prevention of Asthma, Migraine, Migraine Disorders, and Arthritis, Rheumatoid. Imrecoxib Imrecoxib has been used in trials studying the treatment of Knee Osteoarthritis. Taurolidine Taurolidine has been investigated for the prevention of Central Venous Catheter, Home Parenteral Nutrition, and Catheter-Related Infections. Perfosfamide Perfosfamide has been used in trials studying the treatment of Lymphoma, Neuroblastoma, and Multiple Myeloma and Plasma Cell Neoplasm. GS-9256 GS-9256 has been used in trials studying the treatment of HCV Infection and Chronic Hepatitis C Infection. Trofosfamide Trofosfamide has been used in trials studying the treatment of Ependymomas, Medulloblastomas, Sarcoma, Soft Tissue, Supratentorial PNETs, and Recurrent Brain Tumors. CHS-828 CHS-828 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific. QGC-001 QGC001 has been used in trials studying the treatment of Essential Hypertension. Sodium chlorite Used as an agent for cleaning drinking water. It is also used as an additive in products like toothpaste and mouthwash. Acidified sodium chlorite was approved by the U.S. Food... Perboric acid In the industry, sodium perborate is used as a disinfectant. It is also part of the ingredients for detergents, bleach powders, and personal care formulations. In cosmetic products, perboric acid... Stibophen Stibophen is used in the treatment of schistosomiasis, a disease of parasitic flatworms. Magnesium silicate Magnesium silicate is used to absorb moisture, prevent caking, and to improve the feel of a product. In the pharmaceutical companies, it is used as a dietary supplement, as part... Olaflur Olaflur which is also referred to as elmex gel is an ingredient used in toothpaste which helps in the prevention of dental caries. Methiodal Not Annotated Mannosulfan Not Annotated Mercuric amidochloride Not Annotated Mesulfen Not Annotated Hydrochloric acid Not Annotated Antimony pentasulfide Not Annotated Sodium apolate Not Annotated Etamsylate Not Annotated Dobesilic acid Not Annotated Aminoethyl nitrate Not Annotated Almasilate Almasilate is indicated for use as an antacid for the neutralization of excess stomach acid . It is subsequently also used for the symptomatic treatment of diseases where it is... Montmorillonite Not Annotated Dixanthogen Not Annotated Trolnitrate Not Annotated Mercuric chloride Mercury chloride (HgCl2) is a highly toxic compound that volatizes slightly at ordinary temperature and appreciably at 100 degrees C. It is corrosive to mucous membranes and used as a... Calcium silicate Not Annotated Magnesium phosphate Not Annotated Ferric subsulfate Ferric subsulfate is a stypic or hemostatic agent that causes agglutination of surface proteins resulting in local hemostasis. It has the chemical formula Fe4(OH)2(SO4)5. It is used after superficial skin... Potassium carbonate Potassium carbonate (K2CO3) is a white salt, soluble in water (insoluble in ethanol) which forms a strongly alkaline solution. It can be made as the product of potassium hydroxide's absorbent... Sodium zirconium cyclosilicate A potassium binder used to treat hyperkalemia. Nitrate Not Annotated Trabodenoson Trabodenoson has been used in trials studying the treatment of Ocular Hypertension (OHT) and Primary Open-Angle Glaucoma (POAG). Hypochlorous acid An oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent. Silicic acid Not Annotated Fosinoprilat Fosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group. Pumice Pumice is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Calcium phosphate dihydrate For use as an over the counter calcium and phosphate supplement, antacid, or a source of calcium and phosphate in toothpaste [FDA Label] . Bismuth subcarbonate Not Annotated Zinc carbonate Not Annotated Potassium sulfate An osmotic laxative used to cleanse the colon before a colonoscopy. Sodium phosphate, dibasic An osmotic laxative used to cleanse the colon before a colonoscopy. Sodium borate No FDA- or EMA-approved therapeutic indications on its own. Lithium carbonate A medication used to treat manic episodes of bipolar disorder. Aluminium phosphate Not Available Phosphate ion Not Annotated Chromic nitrate Indicated for use as a supplement to intravenous solutions given for total parenteral nutrition (TPN), to maintain chromium serum levels and to prevent depletion of endogenous stores and subsequent deficiency... Zinc chloride A medication used to treat zinc deficiencies and associated symptoms and also in total parenteral nutrition. Borate ion Not Annotated Eprodisate Investigated for use/treatment in amyloidosis. Sodium phosphate tribasic dodecahydrate Not Annotated Acetyl chloride Not Annotated Nitrogen trichloride Not Annotated Phenyl hydrogen sulfate Not Annotated Taurine An ingredient found in mixture products indicated for nutritional support. Irosustat Irosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast Cancer. Monofluorophosphate ion Not Available Benzenesulfinic acid Not Available Triphosphoric acid Used as water softener, peptizing agent, emulsifier & dispersing agent; ingredient of cleansers; meat preservative. Dutogliptin Dutogliptin has been investigated for the treatment of Diabetes Mellitus, Type II. PX-12 Investigated for use/treatment in cancer/tumors (unspecified), gastric cancer, and pancreatic cancer. Becaplermin A recombinant form of human platelet-derived growth factor used to treat ulcers due to diabetic neuropathy in the lower extremities when there is adequate blood supply to the area. Tolevamer A potassium-binding resin used in the treatment of hyperkalemia. LGD-6972 LGD-6972 is under investigation in clinical trial NCT01919684 (Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LGD-6972 in Healthy Subjects and Subjects With Type 2 Diabetes Mellitus). Calcium sulfate Not Annotated Ferric chloride Not Annotated Acid yellow 54 free acid Not Available Phenylboronic acid Not Available 3-(cyclohexylamino)propanesulfonic acid Not Available 1-Naphthylamine-5-sulfonic acid Not Available Benzylsulfonic acid Not Available 2-(N-morpholino)ethanesulfonic acid Not Available Vinylsulfonic acid Not Available 8-anilinonaphthalene-1-sulfonic acid Not Available Lactobacillus acidophilus Not Annotated Diquafosol Not Annotated Ammonium bicarbonate Not Annotated Ammonium carbonate Not Annotated Sodium nitrate Not Annotated Calcium fluoride Not Annotated Tauroselcholic acid Not Annotated Gold sodium thiosulfate Not Annotated Garlic oil Not Annotated Nitric acid Not Annotated NCX-1000 NCX-1000 is under investigation in clinical trial NCT00414869 (Preliminary Efficacy and Tolerability of NCX-1000 After Repeated Oral Doses in Patients With Elevated Portal Pressure). Tetrafluoroborate Tetrafluoroborate is under investigation in clinical trial NCT02907073 (Positron Emission Tomography (PET) Imaging Studies With NIS Reporter). Razuprotafib Razuprotafib, also known as AKB-9778, is a small-molecule inhibitor restoring Tie2 activation by inhibiting VE-PTP.[L27171,L27176] In investigations against diabetes and COVID-19, razuprotafib is self-administered by patients through subcutaneous injection.
- Drugs & Drug Targets