Cyclohexanes
- Name
- Cyclohexanes
- Accession Number
- DBCAT000358
- Description
Six-carbon alicyclic hydrocarbons.
- Drugs
Drug Drug Description Vitamin A A vitamin important for retinal function that is used clinically to correct vitamin A deficiency. Tramadol A centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults. Venlafaxine A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression. Tranexamic acid An antifibrinolytic agent used for heavy menstrual bleeding. Nitisinone A hydroxyphenylpyruvate dioxygenase inhibitor used as an adjunct to dietary restrictions for the treatment of hereditary tyrosinemia type 1 (HT-1), which causes intolerance to tyrosine containing foods. Acitretin An oral retinoid used in the treatment of severe psoriasis. Picrotoxin Used internally for relieving respiratory distress. Also for use as an antidote in poisoning by CNS depressants, especially barbiturates. Hexylcaine Used as a local anesthetic for surface application, infiltration or nerve block Alitretinoin A vitamin A derivative used to treat Kaposi's sarcoma and used off label to treat chronic hand eczema and psoriasis. Adenosine A medication used in myocardial perfusion scintigraphy. Tretinoin A vitamin A derivative used to treat acne vulgaris, certain types of promyelocytic leukemia, and fine wrinkles. Dicyclomine An antimuscarinic agent used to treat IBS. Etretinate For the treatment of severe psoriasis in adults. Isotretinoin A retinoid used to treat severe recalcitrant acne. Gabapentin An anticonvulsant medication used in the management of peripheral neuropathic pains, postherpetic neuralgia, and partial-onset seizures. Ketamine A rapid-acting general anesthetic and NMDA receptor antagonist used for induction of anesthesia diagnostic and surgical procedures typically in combination with a muscle relaxant. 1-Phenylcyclohexylamine Not Available Gabaculine Not Available Cyclohexanone Cyclohexanone (also known as oxocyclohexane, pimelic ketone, ketohexamethylene, cyclohexyl ketone or ketocyclohexane) is a six-carbon cyclic molecule with a ketone functional group. It is a colorless, oily liquid with an... 4-Oxoretinol Not Available Isochorismic Acid Not Available Arotinoid acid Arotinoid acid is a retinoic acid analog which acts as a selective RAR agonist. Peridinin Not Available Violaxanthin Not Available Cyclohexanol Monohydroxy derivatives of cyclohexanes that contain the general formula R-C6H11O. They have a camphorlike odor and are used in making soaps, insecticides, germicides, dry cleaning, and plasticizers. [PubChem] Cilomilast Investigated for use/treatment in chronic obstructive pulmonary disease (COPD). Eucalyptol A common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion. 3-Dehydroquinic Acid Not Available Shikimate-3-Phosphate Not Available 3-Dehydroshikimate Not Available Voglibose For the treatment of diabetes. It is specifically used for lowering post-prandial blood glucose levels thereby reducing the risk of macrovascular complications. Apadenoson Investigated for use/treatment in cardiovascular disorders and inflammatory disorders (unspecified). Fenretinide Investigated for use/treatment in macular degeneration. Atl146e Investigated for use/treatment in inflammatory disorders (unspecified). IRX-5183 Investigated for use/treatment in adverse effects (chemotherapy) and blood (blood forming organ disorders, unspecified). Transcrocetinate Investigated for use/treatment in cancer/tumors (unspecified), hemorrhage, hypoxia, respiratory failure, and strokes. Astaxanthin Investigated for use/treatment in eye disorders/infections, cancer/tumors (unspecified), and asthma. Desvenlafaxine An antidepressant agent and SNRI used for the treatment of major depressive disorders in adults. Ambroxol Ambroxol is indicated for secretolytic therapy in bronchoplmonary diseaes with abnormal mucus secretion and transport. It allows the mucus to be more easily cleared and ease a patient's breathing. Beta carotene A vitamin A precursor found in various nutritional supplements and health products. 3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acid Not Available Prephenic acid Not Available Ro 12-7310 Not Available (4R)-limonene Limonene is common in cosmetic products. As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to... Bromhexine Bromhexine is an expectorant/mucolytic agent. Bromhexine is not available in the United States. It is marketed under the trade name Bisolvon(R) in Germany, England, Belgium, France, Italy, Netherlands, Norway, Sweden,... Zeaxanthin Zeaxanthin is a most common carotenoid alcohols found in nature that is involved in the xanthophyll cycle. As a coexistent isomer of lutein, zeaxanthin is synthesized in plants and some... Lycopene An ingredient found in a variety of supplements and vitamins. Tiletamine This drug is a dissociative anesthetic agent that falls under the drug category of NMDA receptor antagonists. Tiletamine is chemically similar to another dissociative anesthetic, ketamine. Tiletamine hydrochloride, the salt... Candoxatrilat A dicarboxylic acid monoamide obtained by formal condensation between the amino group of cis-4-aminocyclohexanecarboxylic acid and the cyclopentanecarboxylic acid group of 1-[(2S)-2-carboxy-3-(2-methoxyethoxy)propyl]cyclopentanecarboxylic acid. A potent inhibitor of neutral endopeptidase (NEP,... Tanzisertib Tanzisertib has been used in trials studying the treatment of Fibrosis, Discoid Lupus, Pulmonary Fibrosis, Interstitial Lung Disease, and Lung Diseases, Interstitial, among others. Crocin Crocin has been investigated for the treatment of Hyperglycemia, Metabolic Syndrome, Hypertriglyceridemia, and Hypercholesterolemia. Lomibuvir Lomibuvir has been used in trials studying the treatment of Chronic Hepatitis C Virus and Chronic Hepatitis C Virus Infection. Chlorogenic Acid Chlorogenic Acid has been used in trials studying the treatment of Advanced Cancer and Impaired Glucose Tolerance. Zuretinol acetate Zuretinol acetate has been used in trials studying the treatment of Impaired Dark Adaptation, RP (Retinitis Pigmentosa), Retinitis Pigmentosa (RP), and LCA (Leber Congenital Amaurosis). MK-5108 MK-5108 has been used in trials studying the treatment of Cancer, Neoplasms, Tumors. AQX-1125 AQX-1125 has been used in trials studying the treatment of COPD, Atopic Dermatitis, Interstitial Cystitis, and Bladder Pain Syndrome. Gacyclidine Gacyclidine has been used in trials studying the treatment of Tinnitus. Ambroxol acefyllinate Not Annotated Terpin hydrate An expectorant used to treat bronchitis, pneumonia, bronchiectasis, COPD, and infectious or inflammatory diseases of the upper respiratory tract. Neltenexine Neltenexine is an elastase inhibitor. It may be useful for preventing pulmonary emphysema. Motretinide Not Annotated Rociverine Not Annotated Tilidine Not Annotated 13-cis-12-(3'-Carboxyphenyl)retinoic acid Not Annotated Lutein Xanthophylls are taken for nutritional supplementation, and also for treating dietary shortage or imbalance. Oseltamivir acid Not Available Norbixin Norbixin is under investigation in clinical trial NCT03820245 (Effect of Short-term Annatto Carotenoids Supplementation on Oxidative Stress Status in Healthy Individuals). Fucoxanthin Fucoxanthin is under investigation in clinical trial NCT03613740 (Effect of Fucoxanthin on the Components of the Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion). Bexarotene A retinoid drug used for cutaneous manifestations of T-cell lymphoma in patients who have not responded well to previous systemic therapy. Nateglinide A meglitinide used to treat non insulin dependent diabetes mellitus. Ciclopirox A broad-spectrum topical antifungal agent used to treat mild to moderate onychomycosis of fingernails and toenails in immunocompetent patients. Maraviroc A CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection. TNP-470 O-(chloroacetylcarbamoyl)fumagillol (TNP-470) has been used in trials studying the treatment of HIV Infections, Sarcoma, Kaposi, and Pancreatic Neoplasms. Esketamine A NMDA receptor antagonist used for treatment-resistant depression. Levomenthol An organic compound used to treat mild to moderate muscle and joint pain. Anhydrovitamin A Not Available 3-(cyclohexylamino)propanesulfonic acid Not Available N-Ethylretinamide N-Ethylretinamide is the ethylamide of all-trans B-retinoic acid. - Drugs & Drug Targets