Opioids
- Name
- Opioids
- Accession Number
- DBCAT000480
- Description
Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS.
- ATC Classification
- Drugs
Drug Drug Description Alfentanil An opioid agonist used to induce and maintain anesthesia, as well as an analgesic. Alphacetylmethadol A narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence. [PubChem] Alphaprodine Not Annotated Benzhydrocodone Benzyhydrocodone is indicated, in combination with acetaminophen, for the short-term management of acute pain requiring opioid therapy. Bezitramide A narcotic analgesic once used for the treatment of severe chronic pain. Buprenorphine A partial opioid agonist used for management of severe pain that is not responsive to alternative treatments. Also used for maintenance treatment of opioid addiction. Butorphanol An opioid agonist-antagonist used to treat moderate to severe pain. Carfentanil Carfentanil is similar (but more potent) to the opioid analgesic fentanyl. It is used as a tranquilizer for large animals. Carfentanil, C-11 Carfentanil, C-11 is under investigation in clinical trial NCT01899170 (Towards Individualized Deep Brain Stimulation Treatment of Chronic Neuropathic Pain). Codeine An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated. Desomorphine Not Available Dextromethorphan An NMDA receptor antagonist used to treat cases of dry cough. Dextromoramide An opioid analgesic structurally related to methadone and used in the treatment of severe pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1070) Dextropropoxyphene An opioid analgesic used to treat mild to moderate pain. Dezocine Indicated in the treatment of moderate to severe pain. Diamorphine An opioid analgesic agent used in the relief of severe pain associated with surgical procedures, myocardial infarction or pain in the terminally ill and for the relief of dyspnea in acute pulmonary edema. Dihydrocodeine An opioid analgesic agent used for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Dihydroetorphine Not Available Dihydromorphine Dihydromorphine is an opioid analgesic used for moderate to severe pain relief. Dimepheptanol Dimepheptanol is under investigation in clinical trial NCT00218127 (Treatment of Opioid/heroin Dependence: Comparison of Three Medication Dosing Regimens). Diphenoxylate An antidiarrheal medication used with atropine to manage diarrhea. DPDPE A heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond. Eluxadoline A mixed mu-opioid receptor agonist used to treat irritable bowel syndrome with diarrhea. Ethylmorphine An opioid analgesic and antitussive agent used to reduce coughs caused by colds and lung infections in combination with codeine. Etorphine Etorphine is only available for its use in veterinary. This main usage is related to the immobilization of large mammals. Fentanyl An opioid analgesic used in anesthesia, for breakthrough cancer pain, or round the clock pain management. Hydrocodone An opioid agonist used as an analgesic and antitussive agent. Hydromorphone An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated. Ketobemidone For the treatment of all types of severe pain, such as postoperative, cancer, kidney stones and fractures. Levacetylmethadol For the treatment and management of opiate dependence. It is sometimes used to treat severe pain in terminal patients. Levorphanol An opioid analgesic used to treat moderate to severe pain. Lofentanil Lofentanil is an analog of fentanyl and is one of the most potent opioids available today. It displays most similarity to carfentanil (4-carbomethoxyfentanyl) and is considered to be slightly more... Meperidine An opioid agonist with analgesic and sedative properties used to manage severe pain. Meptazinol Not Annotated Methadone An opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction. Methadyl acetate Used mainly in the treatment of narcotic dependence. Methylnaltrexone A μ-opioid antagonist used for the treatment of opioid-induced constipation in palliative patients that are inadequately responding to laxative therapy. Morphine An opioid agonist used for the relief of moderate to severe acute and chronic pain. Nalbuphine An opioid agonist-antagonist used to treat pain, for pre and postoperative analgesia, and for analgesia in labor and delivery. Nalorphine Used to reverse opioid overdose. Naloxegol A peripherally-selective opioid antagonist used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain. Naltrexone A narcotic antagonist used in opioid overdose. Nicomorphine Not Annotated Normethadone An opioid antitussive used to treat a cough associated with inflamed mucosa. Oliceridine A biased opioid agonist indicated for the management of severe acute pain in adult patients. Through preferential activation of G-protein-coupled signalling pathways, oliceridine provides analgesic effect with a comparable or improved safety profile over conventional opioid agonists. Opium A medication used to treat moderate to severe pain. Oxycodone An opioid used in the management of moderate to severe pain. Oxymorphone An opioid analgesic used in the management of moderate-to-severe pain and for analgesic therapies. Pentazocine An analgesic used to treat moderate to severe pain. Phenazocine Not Annotated Phenoperidine Not Annotated Piritramide A synthetic opioid used in the treatment of severe pain. Remifentanil An opioid analgesic used in anesthesia. Sufentanil An opioid used to induce and maintain anesthesia, to act as an analgesic in labor and delivery, and to treat severe, acute pain. Tapentadol An opioid used to manage severe pain that has not responded to non-opioid medications, and for which opioid analgesic therapy is appropriate. Tilidine A synthetic opioid indicated in the treatment of severe pain. Tramadol A centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults.