Folic Acid Antagonists

All categories
DBCAT000523Therapeutic category

Inhibitors of the enzyme, dihydrofolate reductase (TETRAHYDROFOLATE DEHYDROGENASE), which converts dihydrofolate (FH2) to tetrahydrofolate (FH4). They are frequently used in cancer chemotherapy. A DrugBank category of 20 drugs. 12 of them are approved.

Also known as
Acid Antagonists, Folic · Antagonists, Folic Acid · Antifolates · Dihydrofolate Reductase Inhibitor Antibacterial · Dihydrofolate Reductase Inhibitor Antimalarial
Drugs

What you can answer from here — as of August 12, 2019

20DrugsEach linked to its full drug card
Listed above
31Drug targetsEvery drug–target pair in the class, with bond type
Sign in
3,267Marketed productsAcross the regions we cover, with dosage forms and routes
Sign in
15Routes of administrationHow the drugs in this class are given
Sign in

Which targets do Folic Acid Antagonists share, and which companies have late-stage candidates in this class?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In