- Accession Number
A group of compounds with the heterocyclic ring structure of benzo(c)pyridine. The ring structure is characteristic of the group of opium alkaloids such as papaverine. (From Stedman, 25th ed)
Drug Drug Description Nelfinavir A viral protease inhibitor used in the treatment of HIV infection. Metocurine iodide For use as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy. Cisatracurium A skeletal muscle relaxant used to facilitate tracheal intubation, muscle relaxation in surgery, or mechanical ventilation. Moexipril An angiotensin converting enzyme inhibitor prodrug used to treat hypertension. Apomorphine A morphine derivative D2 dopamine agonist used to treat hypomobile "off" episodes of advanced Parkinson's disease. Atracurium besylate A non-depolarizing neuromuscular blocker used to facilitate endotracheal intubation and relax skeletal muscles during surgery. Quinapril An ACE inhibitor prodrug used to treat hypertension, congestive heart failure, and slow rate of progression of renal disease. Praziquantel An anthelmintic medication used to treat a number of parasitic worm infections such as schistosomiasis. Papaverine An alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms". Tubocurarine Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to... Saquinavir An HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency. Metocurine Metocurine is a muscle relaxant. Solifenacin A muscarinic antagonist with antispasmodic properties used to treat urge urinary incontinence, urgency, and urinary frequency associated with an overactive bladder. Berberine An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal... Hydroxyfasudil Not Available Nomifensine Nomifensine, formerly marketed as Merital capsules, was associated with an increased incidence of hemolytic anemia. The approved application holder removed Merital capsules from the market on January 23, 1986. FDA... Debrisoquine For the treatment of moderate and severe hypertension, either alone or as an adjunct, and for the treatment of renal hypertension. Elacridar For the treatment of solid tumors. Amonafide Investigated for use/treatment in breast cancer, ovarian cancer, and prostate cancer. Trabectedin An alkylating agent approved for the treatment of unresectable or metastatic soft tissue sarcoma (liposarcoma or leiomyosarcoma). Noscapine A non-sedating isoquinoline alkaloid used primarily for its antitussive properties. Drotaverine A phosphodiesterase-4 inhibitor used to alleviate gastrointestinal and genitourinary smooth muscle spasms. S-23 An androgen receptor modulator. 5-(2-methylpiperazine-1-sulfonyl)isoquinoline Not Available 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline Potent reversible inhibitor of phenylethanolamine N-methyltransferase. Bicuculline Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and... Tetrahydropalmatine Tetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity). Moxaverine Moxaverine has been investigated for the treatment of Retina, Ocular Physiology, and Regional Blood Flow. Zalypsis Zalypsis has been used in trials studying the treatment of Lymphoma, Solid Tumors, Ewing's Sarcoma, Endometrial Cancer, and Uterine Cervical Cancer, among others. Higenamine Higenamine is under investigation in clinical trial NCT01451229 (Pharmacokinetics and Pharmacodynamics of Higenamine in Chinese Healthy Subjects). Atracurium A neuromuscular blocker indicated to relax muscles during mechanical ventilation under general anesthesia or intubation. Emetine Not Annotated Alcuronium A non-depolarizing skeletal muscle relaxant similar to tubocurarine. It is used as an anesthesia adjuvant. Tretoquinol Not Annotated Dehydroemetine Not Annotated Tetrandrine Not Annotated Moexiprilat The active metabolite of the prodrug Moexipril. Quinaprilat The active metabolite of the prodrug quinapril. Fasudil Fasudil has been investigated in Carotid Stenosis. Palonosetron A serotonin antagonist used in the prophylaxis or management of vomiting that results from emetogenic chemotherapy, and for the management of postoperative nausea and vomiting. Mivacurium A short-acting non-depolarizing neuromuscular blocking agent used to induce anesthesia during intubation and promote skeletal muscle relaxation during surgery or mechanical ventilation. Revaprazan Revaprazan is under investigation in clinical trial NCT01750437 (Phase 2 Clinical Trial to Investigate the Safety, Tolerability and Efficacy of YH1885L in Patients With Non-erosive Reflux Disease(nerd)).
- Drugs & Drug Targets