- Accession Number
Polyacenes with four ortho-fused benzene rings in a straight linear arrangement. This group is best known for the subclass called TETRACYCLINES.
Drug Drug Description Doxycycline A tetracycline antibiotic used to treat a wide variety of bacterial infections. Lymecycline A tetracycline antibiotic used for the treatment of acne vulgaris and other susceptible infections. Valrubicin An anthracycline used intravesically in the treatment of BCG-resistant bladder carcinoma. Epirubicin An anthracycline topoisomerase II inhibitor used as an adjuvant to treating axillary node metastases in patients who have undergone surgical resection of primary breast cancer. Clomocycline For the treatment and management of Brucellosis, mycoplasma infection, acne vulgaris, chlamydial infection;Chronic bronchitis Tigecycline A glycylcycline antibiotic used to treat a number of susceptible bacterial infections. Oxytetracycline A tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections. Demeclocycline A tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections. Daunorubicin An anthracycline aminoglycoside used to induce remission of nonlymphocytic leukemia and acute lymphocytic leukemia. Tetracycline An antibiotic used to treat a wide variety of susceptible infections. Metacycline For the treatment of acute bacterial exacerbations of chronic bronchitis Doxorubicin A medication used to treat various cancers and Kaposi's Sarcoma. Minocycline A tetracycline analog used to treat a wide variety of infections in the body. Idarubicin An anthracycline antineoplastic agent used to treat acute myeloid leukemia (AML) in adults. Rolitetracycline A broad-spectrum tetracycline antibiotic used in cases needing high concentrations or when oral administration is impractical. SP1049C Intended for the treatment of carcinoma of the oesophagus. Aldoxorubicin Investigated for use/treatment in solid tumors. Amrubicin Investigated for use/treatment in lung cancer . Annamycin Investigated for use/treatment in breast cancer and leukemia (unspecified). Plicamycin For the treatment of testicular cancer, as well as hypercalcemia and hypercalciuria associated with a variety of advanced forms of cancer. Chlortetracycline The first tetracycline antibiotic most commonly used for veterinary purposes. Pirarubicin Not Annotated Aclarubicin Not Annotated Zorubicin Zorubicin is a drug of the anthracycline class - a class of medications that have historically demonstrated effective chemotherapy for a variety of cancer types. Eravacycline A tetracycline antibiotic used to treat complicated intra-abdominal infections. Sabarubicin Sabarubicin has been used in trials studying the treatment of Prostate Cancer, Testicular Germ Cell Tumor, and Unspecified Adult Solid Tumor, Protocol Specific. Omadacycline A tetracycline antibiotic used to treat community acquired bacterial pneumonia. Zoptarelin doxorubicin Zoptarelin doxorubicin has been used in trials studying the treatment of Breast Cancer, Ovarian Cancer, Prostate Cancer, Endometrial Cancer, and Urothelial Carcinoma, among others. GPX-150 GPX-150 has been used in trials studying the treatment of Soft Tissue Sarcoma and Advanced Solid Tumors - Phase 1 Population. Penimepicycline Penimepicycline is a tetracycline-class antibiotic. It is mentioned on List A produced by the Government of Canada, which is a list of antimicrobial active pharmaceutical ingredients . In the classification... Meclocycline Currently under investigation for the topical treatment of ulcerative oral mucositis DTS-201 Investigated for use/treatment in cancer/tumors (unspecified). Sarecycline A tetracycline antibiotic used to treat inflammatory lesions of non-nodular moderate to severe acne vulgaris. Gancotamab Gancotamab is under investigation in clinical trial NCT02213744 (MM-302 Plus Trastuzumab vs. Chemotherapy of Physician's Choice Plus Trastuzumab in HER2-Positive Locally Advanced/Metastatic Breast Cancer Patients). TP-271 TP-271 is under investigation in clinical trial NCT02724085 (A Phase 1 Study to Assess the Safety, Tolerability and PK of IV TP-271). Incyclinide Incyclinide has been used in trials studying the treatment of HIV Infection, AIDS-related Kaposi Sarcoma, Brain and Central Nervous System Tumors, and Unspecified Adult Solid Tumor, Protocol Specific. Nanoparticle Epirubicin Nanoparticle Epirubicin is under investigation in clinical trial NCT03168061 (Dose-escalation and Expansion Trial of NC-6300 in Patients With Advanced Solid Tumors or Soft Tissue Sarcoma).
- Drugs & Drug Targets