- Opiate Alkaloids
- Accession Number
Alkaloids found in OPIUM from PAPAVER that induce analgesic and narcotic effects by action upon OPIOID RECEPTORS.
Drug Drug Description Morphine An opioid agonist used for the relief of moderate to severe acute and chronic pain. Codeine An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated. Hydromorphone An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated. Oxycodone An opioid used in the management of moderate to severe pain. Dextromethorphan An NMDA receptor antagonist used to treat cases of dry cough. Hydrocodone An opioid agonist used as an analgesic and antitussive agent. Papaverine An alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms". Naloxone An opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection. Noscapine A non-sedating isoquinoline alkaloid used primarily for its antitussive properties. Drotaverine A phosphodiesterase-4 inhibitor used to alleviate gastrointestinal and genitourinary smooth muscle spasms. Samidorphan A novel opioid-system modulator, similar to naltrexone, that functions primarily as a μ-opioid receptor antagonist in vivo and is used primarily in combination with antipsychotics to reduce their metabolic dysfunction-associated adverse effects. Levallorphan For the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids. Butorphanol An opioid agonist-antagonist used to treat moderate to severe pain. Pentazocine An analgesic used to treat moderate to severe pain. Naltrexone A narcotic antagonist used in opioid overdose. Nalbuphine An opioid agonist-antagonist used to treat pain, for pre and postoperative analgesia, and for analgesia in labor and delivery. Levorphanol An opioid analgesic used to treat moderate to severe pain. Buprenorphine A partial opioid agonist used for management of severe pain that is not responsive to alternative treatments. Also used for maintenance treatment of opioid addiction. Oxymorphone An opioid analgesic used in the management of moderate-to-severe pain and for analgesic therapies. 5-Methoxy-N,N-diisopropyltryptamine 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) is a tryptamine derivative and shares many similarities with schedule I tryptamine hallucinogens such as alpha-ethyltryptamine, N,N-dimethyltryptamine, N,N-diethyltryptamine, bufotenine, psilocybin and psilocin. Since 1999, there has been a... Dihydroetorphine Not Available Diamorphine An opioid analgesic agent used in the relief of severe pain associated with surgical procedures, myocardial infarction or pain in the terminally ill and for the relief of dyspnea in acute pulmonary edema. Ethylmorphine An opioid analgesic and antitussive agent used to reduce coughs caused by colds and lung infections in combination with codeine. Cyprenorphine Not Available Etorphine Etorphine is only available for its use in veterinary. This main usage is related to the immobilization of large mammals. Desomorphine Not Available Drotebanol Not Available Diprenorphine Diprenorphine is indicated to reverse the effects of powerful opioids including etorphine and carfentanil, often used for tranquilizing large animals. This drug is not approved for use in humans. Dihydrocodeine An opioid analgesic agent used for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Dihydromorphine Dihydromorphine is an opioid analgesic used for moderate to severe pain relief. Nalmefene An opioid antagonist used to reduce alcohol consumption in adults with alcohol dependence and treat and prevent opioid overdose. Morphine glucuronide Investigated for use/treatment in pain (acute or chronic). Methylnaltrexone A μ-opioid antagonist used for the treatment of opioid-induced constipation in palliative patients that are inadequately responding to laxative therapy. Naloxegol A peripherally-selective opioid antagonist used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain. Pholcodine An opioid antitussive used to suppress unproductive coughing. Nalorphine Used to reverse opioid overdose. Naldemedine An opioid antagonist used to to treat opioid-induced constipation. Moxaverine Moxaverine has been investigated for the treatment of Retina, Ocular Physiology, and Regional Blood Flow. Nicomorphine Not Annotated Nalfurafine Not Annotated Phenazocine Not Annotated Dimemorfan Not Annotated Loxicodegol Loxicodegol was developed as an opioid analgesic with low abuse potential for use in treating chronic pain . An application has been filed for FDA approval of Loxicodegol for use... Dextrorphan Not Annotated Sinomenine Not Annotated
- Drugs & Drug Targets