Pregnenediones
- Name
- Pregnenediones
- Accession Number
- DBCAT000827
- Description
Unsaturated pregnane derivatives containing two keto groups on side chains or ring structures.
- Drugs
Drug Drug Description Progesterone A hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia. Medroxyprogesterone acetate A progestin used as a contraceptive and in the treatment of secondary amenorrhea, abnormal uterine bleeding, pain from endometriosis, endometrial and renal carcinomas, paraphilia in males, and GnRH-dependent precocious puberty. Hydrocortisone A glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders. Flurandrenolide A corticosteroid used to treat corticosteroid-responsive dermatoses. Budesonide A corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis. Corticosterone An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437) Halcinonide A corticosteroid used for the management and symptomatic relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Clascoterone An androgen receptor antagonist used for the topical treatment of acne vulgaris in patients 12 years of age and older. Desoxycortone Not Annotated Aldosterone A hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium. Gestonorone caproate Not Annotated Desoxycorticosterone pivalate Examined for treatment of adrenocortical insufficiency especially in multiple sclerosis, congenital cerebral palsy, polyarteritis nodosa, and rheumatoid arthritis. Currently only approved in treating cats and dogs for the treatment of... Anecortave acetate Investigated for use/treatment in glaucoma and macular degeneration. NCX 1022 Investigated for use/treatment in atopic dermatitis. Desoxycorticosterone acetate Not Annotated Hydroxyprogesterone caproate A synthetic progestin used for the prevention of spontaneous preterm births in singleton pregnancies in women who have previously had a spontaneous preterm birth. Tixocortol A corticosteroid used for the symptomatic treatment of rhinitis, pharyngitis, and ulcerative colitis. Brexanolone Brexanolone is a synthetic neuroactive steroid gamma-aminobutyric acid A (GABA(a)) receptor positive modulator indicated for the treatment of postpartum depression (PPD) in adult women [FDA Label][A176080, A176083, F4063, F4066, F4072]. Anecortave Anecortave is under investigation in clinical trial NCT00691717 (Anecortave Acetate Safety in Patients With Open-Angle Glaucoma or Ocular Hypertension). Flumedroxone Not Annotated Hydrocortisone aceponate For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many... Hydrocortisone acetate A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses and ulcerative colitis. Hydrocortisone butyrate A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. Hydrocortisone cypionate For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many... Hydrocortisone phosphate A corticosteroid used to treat congenital adrenal hyperplasia, for emergency asthma treatment, hypersensitivity, and inflammation. Hydrocortisone probutate A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. Hydrocortisone valerate A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. Hydrocortisone succinate A corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders. Hydroxyprogesterone Not Annotated Algestone acetophenide A progestin indicated in combination with an estrogen as an injectable contraceptive. Algestone Not Available - Drugs & Drug Targets