Urologicals

Name
Urologicals
Accession Number
DBCAT002207
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
TrospiumAn antimuscarinic agent used to treat the symptoms of overactive bladder (OAB).
AlfuzosinAn alpha-1 adrenergic antagonist used in the symptomatic management of benign prostatic hypertrophy (BPH).
DarifenacinAn M3 muscarinic receptor blocker used to treat urinary incontinence.
Acetohydroxamic acidA synthetic urea derivative used to treat urea splitting bacterial infections of the urinary tract.
Pentosan polysulfateA sulfated pentosyl polysaccharide used to treat bladder pain and discomfort due to interstitial cystitis.
TamsulosinAn alpha-1A and alpha-1B adrenergic receptor antagonist used to treat benign prostatic hyperplasia, ureteral stones, prostatitis, and female voiding dysfunction.
AlprostadilA prostaglandin E1 agonist used for the treatment of erectile dysfunction and as an adjunct for its diagnosis.
TadalafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension.
VardenafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction.
TolterodineA muscarinic receptor antagonist used to treat overactive bladder with urinary incontinence, urgency, and frequency.
OxybutyninAn antimuscarinic agent that reduces detrusor muscle activity, relaxing the bladder and preventing the urge to void.
DutasterideAn antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) in adult males by inhibiting 5-alpha reductase.
FlavoxateA muscarinic antagonist and spasmolytic used for the symptomatic relief of conditions associated with lack of muscle control in the bladder, such as dysuria, urgency, and nocturia.
TerazosinAn alpha-1 adrenergic antagonist used in the treatment of symptomatic benign prostatic hyperplasia and management of hypertension.
Calcium chlorideAn ionic compound used for the treatment of hypocalcemia and hyperkalemia, and as an antidote to magnesium intoxication due to overdosage of magnesium sulfate.
FinasterideAn antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) and male pattern hair loss in adult males by inhibiting Type II 5-alpha reductase.
YohimbineAn alpha-2-adrenergic blocker and sympatholytic found in supplements used to.
PhenazopyridineA local anesthetic used for the symptomatic relief of pain, burning, urgency, frequency, and general discomfort caused by lower urinary tract irritations that are a result of infection, trauma, surgery, endoscopic procedures, or the passage of equipment or catheters.
SolifenacinA muscarinic antagonist with antispasmodic properties used to treat urge urinary incontinence, urgency, and urinary frequency associated with an overactive bladder.
DapoxetineA selective serotonin reuptake inhibitor used in the treatment of premature ejaculation.
SilodosinAn alpha-1 adrenergic receptor antagonist used to treat symptoms associated with benign prostatic hyperplasia (BPH).
AvanafilA phosphodiesterase-5 (PDE5) inhibitor used to treat erectile dysfunction.
UdenafilA PDE5 inhibitor used to treat erectile dysfunction.
FesoterodineAn antimuscarinic agent used in the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency.
MirabegronA beta-3 adrenergic agonist used to treat overactive bladder and neurogenic detrusor overactivity.
Magnesium hydroxideAn inorganic compound used as a laxative and antacid.
MoxisylyteAccording to the WHO, moxisylyte is indicated for the symptomatic management of sequelae of cerebral infarction or hemorrhage. The cerebral infarction is characterized by the blockage of the artery either...
Phenyl salicylatePain and fever .
PropiverineAn antimuscarinic agent used to treat urinary incontinence or increased urinary frequency or urgency.
MeladrazineNot Annotated
SuccinimideNot Annotated
EmeproniumNot Annotated
TerodilineNot Annotated
ApomorphineA morphine derivative D2 dopamine agonist used to treat hypomobile "off" episodes of advanced Parkinson's disease.
Dimethyl sulfoxideA reversible mitogen-activated extracellular signal-regulated kinase-1 (MEK1) and MEK2 inhibitor used to treat certain types of melanoma, metastatic non-small cell lung cancer, and locally advanced or metastatic anaplastic thyroid cancer.
PapaverineAn alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms".
Ammonium chlorideExpectorant in cough syrups. The ammonium ion (NH4+) in the body plays an important role in the maintenance of acid-base balance. The kidney uses ammonium (NH4+) in place of sodium...
MepartricinA medication indicated in the treatment of benign prostatic hyperplasia, vaginal candidiasis, or trichomoniasis.
TioproninA thiol agent indicated for the prevention of kidney stone formation in patients with severe homozygous cystinuria.
SildenafilA phosphodiesterase inhibitor used for the treatment of erectile dysfunction.
DesfesoterodineAn antimuscarinic agent indicated in the symptomatic treatment of urinary frequency or incontinence.
DoxazosinAn alpha-1 adrenergic receptor used to treat mild to moderate hypertension and urinary obstruction due to benign prostatic hyperplasia.
ImidafenacinAn antispasmodic with anticholinergic effects used to reduce urinary frequency.
Salicylic acidAn acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
MethenamineA urinary tract antiseptic and antibacterial drug used for the prophylaxis and treatment of frequently recurring urinary tract infections requiring a long-term therapy.
VibegronA beta-3 adrenergic agonist the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency in adults.
Drugs & Drug Targets
DrugTargetType
TrospiumMuscarinic acetylcholine receptor M1target
TrospiumCytochrome P450 2D6enzyme
TrospiumMuscarinic acetylcholine receptor M3target
TrospiumMuscarinic acetylcholine receptor M5target
AlfuzosinAlpha-1A adrenergic receptortarget
AlfuzosinAlpha-1B adrenergic receptortarget
AlfuzosinAlpha-1D adrenergic receptortarget
AlfuzosinCytochrome P450 3A4enzyme
AlfuzosinATP-dependent translocase ABCB1transporter
AlfuzosinAlpha-1 adrenergic receptorstarget
AlfuzosinAlbumincarrier
AlfuzosinAlpha-1-acid glycoprotein 1carrier
DarifenacinMuscarinic acetylcholine receptor M3target
DarifenacinCytochrome P450 3A4enzyme
DarifenacinCytochrome P450 2D6enzyme
DarifenacinMuscarinic acetylcholine receptor M1target
DarifenacinMuscarinic acetylcholine receptor M2target
DarifenacinMuscarinic acetylcholine receptor M4target
DarifenacinMuscarinic acetylcholine receptor M5target
Acetohydroxamic acidUrease subunit alphatarget
Acetohydroxamic acidMacrophage metalloelastasetarget
Pentosan polysulfateFibroblast growth factor 1target
Pentosan polysulfateFibroblast growth factor 4target
Pentosan polysulfateFibroblast growth factor 2target
TamsulosinAlpha-1A adrenergic receptortarget
TamsulosinAlpha-1D adrenergic receptortarget
TamsulosinAlpha-1B adrenergic receptortarget
TamsulosinAlpha-1-acid glycoprotein 1carrier
TamsulosinCytochrome P450 2D6enzyme
TamsulosinCytochrome P450 3A4enzyme
AlprostadilProstaglandin E2 receptor EP2 subtypetarget
AlprostadilProstaglandin E2 receptor EP1 subtypetarget
AlprostadilATP-binding cassette sub-family C member 5transporter
AlprostadilSolute carrier organic anion transporter family member 2B1transporter
AlprostadilSolute carrier organic anion transporter family member 3A1transporter
AlprostadilATP-binding cassette sub-family C member 4transporter
AlprostadilSolute carrier organic anion transporter family member 2A1transporter
AlprostadilProstaglandin D2 receptor 2target
AlprostadilSolute carrier family 22 member 6transporter
Alprostadil15-hydroxyprostaglandin dehydrogenase [NAD(+)]enzyme
AlprostadilAlbumincarrier
AlprostadilProstaglandin E2 receptor EP3 subtypetarget
AlprostadilProstaglandin E2 receptor EP4 subtypetarget
AlprostadilThromboxane A2 receptortarget
TadalafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
TadalafilCytochrome P450 3A4enzyme
TadalafilDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11Atarget
TadalafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
VardenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
VardenafilCytochrome P450 3A4enzyme
VardenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
VardenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
VardenafilCytochrome P450 3A5enzyme
VardenafilATP-dependent translocase ABCB1transporter
VardenafilCytochrome P450 2C9enzyme
VardenafilCytochrome P450 2C8enzyme
VardenafilCytochrome P450 2C19enzyme
VardenafilCytochrome P450 2D6enzyme
TolterodineMuscarinic acetylcholine receptor M1target
TolterodineMuscarinic acetylcholine receptor M2target
TolterodineMuscarinic acetylcholine receptor M3target
TolterodineCytochrome P450 2D6enzyme
TolterodineCytochrome P450 3A4enzyme
TolterodineCytochrome P450 2C9enzyme
TolterodineCytochrome P450 2C19enzyme
TolterodineMuscarinic acetylcholine receptor M4target
TolterodineMuscarinic acetylcholine receptor M5target
OxybutyninMuscarinic acetylcholine receptor M1target
OxybutyninMuscarinic acetylcholine receptor M2target
OxybutyninMuscarinic acetylcholine receptor M3target
OxybutyninCytochrome P450 3A4enzyme
OxybutyninCytochrome P450 2C8enzyme
OxybutyninCytochrome P450 2D6enzyme
OxybutyninCytochrome P450 3A5enzyme
OxybutyninAlpha-1-acid glycoprotein 1carrier
OxybutyninAlbumincarrier
Dutasteride3-oxo-5-alpha-steroid 4-dehydrogenase 1target
Dutasteride3-oxo-5-alpha-steroid 4-dehydrogenase 2target
DutasterideSodium-dependent dopamine transportertransporter
DutasterideSynaptic vesicular amine transportertransporter
DutasterideAlbumincarrier
DutasterideAlpha-1-acid glycoprotein 1carrier
DutasterideCytochrome P450 3A5enzyme
DutasteridePolyprenol reductasetarget
FlavoxateMuscarinic acetylcholine receptor M1target
FlavoxateMuscarinic acetylcholine receptor M2target
FlavoxateMuscarinic acetylcholine receptor M5target
TerazosinAlpha-1A adrenergic receptortarget
TerazosinAlpha-1B adrenergic receptortarget
TerazosinAlpha-1D adrenergic receptortarget
TerazosinPotassium voltage-gated channel subfamily H member 2target
TerazosinPotassium voltage-gated channel subfamily H member 6target
TerazosinPotassium voltage-gated channel subfamily H member 7target
TerazosinATP-dependent translocase ABCB1transporter
TerazosinTransforming growth factor beta-1 proproteintarget
Calcium chlorideProtein S100-A13target
Finasteride3-oxo-5-alpha-steroid 4-dehydrogenase 1target
FinasterideCytochrome P450 3A4enzyme
Finasteride3-oxo-5-alpha-steroid 4-dehydrogenase 2target
FinasterideAldo-keto reductase family 1 member D1target
FinasterideCytochrome P450 3A5enzyme
FinasterideCytochrome P450 3A7enzyme
FinasterideSolute carrier family 12 member 5transporter
FinasteridePolyprenol reductasetarget
YohimbineAlpha-2A adrenergic receptortarget
YohimbineAlpha-2B adrenergic receptortarget
YohimbineAlpha-2C adrenergic receptortarget
Yohimbine5-hydroxytryptamine receptor 1Atarget
Yohimbine5-hydroxytryptamine receptor 1Btarget
Yohimbine5-hydroxytryptamine receptor 1Dtarget
YohimbineD(2) dopamine receptortarget
YohimbineD(3) dopamine receptortarget
Yohimbine5-hydroxytryptamine receptor 2Atarget
Yohimbine5-hydroxytryptamine receptor 2Ctarget
YohimbineCytochrome P450 2D6enzyme
YohimbineCytochrome P450 3A4enzyme
YohimbineATP-sensitive potassium channeltarget
Yohimbine5-hydroxytryptamine receptor 2Btarget
PhenazopyridineSodium channel protein type 1 subunit alphatarget
PhenazopyridineGroup A nerve fiberstarget
SolifenacinMuscarinic acetylcholine receptor M3target
SolifenacinMuscarinic acetylcholine receptor M1target
SolifenacinCytochrome P450 3A4enzyme
SolifenacinMuscarinic acetylcholine receptor M2target
SolifenacinMuscarinic acetylcholine receptor M4target
SolifenacinMuscarinic acetylcholine receptor M5target
Solifenacinalpha1-acid glycoproteincarrier
SolifenacinCytochrome P450 1A1enzyme
SolifenacinCytochrome P450 2D6enzyme
Dapoxetine5-hydroxytryptamine receptor 1Atarget
Dapoxetine5-hydroxytryptamine receptor 1Btarget
Dapoxetine5-hydroxytryptamine receptor 2Ctarget
DapoxetineCytochrome P450 3A4enzyme
DapoxetineCytochrome P450 2D6enzyme
SilodosinAlpha-1D adrenergic receptortarget
SilodosinCytochrome P450 3A4enzyme
SilodosinATP-dependent translocase ABCB1transporter
SilodosinPhosphatidylcholine translocator ABCB4transporter
SilodosinAlpha-1A adrenergic receptortarget
SilodosinAlpha-1B adrenergic receptortarget
SilodosinUDP-glucuronosyltransferase 2B7enzyme
SilodosinAldehyde dehydrogenase, mitochondrialenzyme
SilodosinAldo-keto reductase family 1 member A1enzyme
SilodosinHERG human cardiac K+ channeltarget
AvanafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
AvanafilCytochrome P450 3A4enzyme
AvanafilAlbumincarrier
AvanafilAlpha-1-acid glycoprotein 1carrier
AvanafilATP-dependent translocase ABCB1transporter
AvanafilBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
AvanafilCytochrome P450 2C9enzyme
UdenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
UdenafilCytochrome P450 3A4enzyme
UdenafilCytochrome P450 3A5enzyme
FesoterodineMuscarinic acetylcholine receptor M1target
FesoterodineMuscarinic acetylcholine receptor M3target
FesoterodineCytochrome P450 3A4enzyme
FesoterodineMuscarinic acetylcholine receptor M2target
FesoterodineMuscarinic acetylcholine receptor M4target
FesoterodineMuscarinic acetylcholine receptor M5target
FesoterodineCytochrome P450 2D6enzyme
FesoterodineATP-dependent translocase ABCB1transporter
MirabegronCytochrome P450 3A4enzyme
MirabegronCytochrome P450 2D6enzyme
MirabegronATP-dependent translocase ABCB1transporter
MirabegronSolute carrier organic anion transporter family member 1A2transporter
MirabegronAlbumincarrier
MirabegronAlpha-1-acid glycoprotein 1carrier
MirabegronCholinesteraseenzyme
MirabegronBeta-3 adrenergic receptortarget
MirabegronUDP-glucuronosyltransferase 2B7enzyme
MirabegronUDP-glucuronosyltransferase 1A3enzyme
MirabegronUDP-glucuronosyltransferase 1A8enzyme
MirabegronSolute carrier family 22 member 1transporter
MirabegronSolute carrier family 22 member 2transporter
MirabegronSolute carrier family 22 member 3transporter
MirabegronBeta-1 adrenergic receptortarget
MoxisylyteCholinesteraseenzyme
MoxisylyteCytochrome P450 3A Subfamilyenzyme
MoxisylyteAlpha adrenergic receptortarget
MoxisylyteAlpha-1D adrenergic receptortarget
Phenyl salicylateProstaglandin G/H synthase 1target
Phenyl salicylateProstaglandin G/H synthase 2target
PropiverineMuscarinic acetylcholine receptor M1target
PropiverineMuscarinic acetylcholine receptor M2target
PropiverineMuscarinic acetylcholine receptor M3target
PropiverineMuscarinic acetylcholine receptor M4target
PropiverineMuscarinic acetylcholine receptor M5target
PropiverineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
PropiverineAlpha-1A adrenergic receptortarget
PropiverineCytochrome P450 3A4enzyme
PropiverineFlavin-containing monooxygenase 1enzyme
PropiverineFlavin-containing monooxygenase 3enzyme
EmeproniumMuscarinic acetylcholine receptor M5target
TerodilineCytochrome P450 3A4enzyme
ApomorphineD(2) dopamine receptortarget
ApomorphineD(1A) dopamine receptortarget
ApomorphineD(4) dopamine receptortarget
ApomorphineD(3) dopamine receptortarget
ApomorphineD(1B) dopamine receptortarget
ApomorphineAlpha-2C adrenergic receptortarget
ApomorphineAlpha-2B adrenergic receptortarget
Apomorphine5-hydroxytryptamine receptor 2Ctarget
Apomorphine5-hydroxytryptamine receptor 1Atarget
Apomorphine5-hydroxytryptamine receptor 2Atarget
Apomorphine5-hydroxytryptamine receptor 2Btarget
ApomorphineAlpha-2A adrenergic receptortarget
Apomorphine5-hydroxytryptamine receptor 1Dtarget
Apomorphine5-hydroxytryptamine receptor 1Btarget
ApomorphineCatechol O-methyltransferaseenzyme
ApomorphineSulfotransferase 1A1enzyme
ApomorphineSulfotransferase 1A2enzyme
ApomorphineSulfotransferase 1A3enzyme
ApomorphineSulfotransferase 1E1enzyme
ApomorphineSulfotransferase 1B1enzyme
ApomorphineCytochrome P450 2B6enzyme
ApomorphineCytochrome P450 2C8enzyme
ApomorphineCytochrome P450 3A4enzyme
ApomorphineCytochrome P450 3A5enzyme
ApomorphineUDP-glucuronosyltransferases (UGTs)enzyme
ApomorphineAlbumincarrier
ApomorphineSynaptic vesicular amine transportertransporter
Dimethyl sulfoxideTransthyretincarrier
Dimethyl sulfoxideCytochrome P450 2C19enzyme
Dimethyl sulfoxideCytochrome P450 2D6enzyme
Dimethyl sulfoxideCytochrome P450 3A4enzyme
Dimethyl sulfoxideInterleukin-5 receptor subunit alphatarget
Dimethyl sulfoxideMucin-16target
Dimethyl sulfoxideMyc proto-oncogene proteintarget
Papaverine3',5'-cyclic-AMP phosphodiesterase 4Btarget
PapaverinecAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
PapaverinePhosphodiesterase enzymestarget
PapaverinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
Papaverine3',5'-cyclic-AMP phosphodiesterase 4Dtarget
TioproninMyeloperoxidaseenzyme
SildenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
SildenafilCytochrome P450 2C9enzyme
SildenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
SildenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
SildenafilCytochrome P450 3A4enzyme
SildenafilCytochrome P450 3A5enzyme
SildenafilCytochrome P450 3A7enzyme
SildenafilATP-binding cassette sub-family C member 4transporter
SildenafilATP-binding cassette sub-family C member 5transporter
SildenafilATP-binding cassette sub-family C member 10transporter
SildenafilCytochrome P450 2C19enzyme
SildenafilCytochrome P450 2D6enzyme
SildenafilCytochrome P450 2E1enzyme
SildenafilSolute carrier organic anion transporter family member 1B1transporter
SildenafilATP-dependent translocase ABCB1transporter
SildenafilOrnithine decarboxylasetarget
SildenafilProgrammed cell death 1 ligand 1target
SildenafilPlasma protease C1 inhibitortarget
DoxazosinAlpha-1A adrenergic receptortarget
DoxazosinAlpha-1D adrenergic receptortarget
DoxazosinHERG human cardiac K+ channeltarget
DoxazosinATP-dependent translocase ABCB1transporter
DoxazosinCytochrome P450 2C19enzyme
DoxazosinCytochrome P450 2D6enzyme
DoxazosinSolute carrier family 22 member 1transporter
DoxazosinCytochrome P450 3A4enzyme
DoxazosinAlpha-1B adrenergic receptortarget
DoxazosinCytochrome P450 2C9enzyme
ImidafenacinMuscarinic acetylcholine receptor M1target
ImidafenacinMuscarinic acetylcholine receptor M2target
ImidafenacinMuscarinic acetylcholine receptor M3target
ImidafenacinCytochrome P450 3A4enzyme
ImidafenacinUDP-glucuronosyltransferase 1A4enzyme
ImidafenacinAlbumincarrier
Imidafenacinalpha1-acid glycoproteincarrier
Salicylic acidAlbumincarrier
Salicylic acidProstaglandin G/H synthase 1target
Salicylic acidProstaglandin G/H synthase 2target
Salicylic acidAldo-keto reductase family 1 member C1target
Salicylic acidSolute carrier family 22 member 6transporter
Salicylic acidSolute carrier family 22 member 10transporter
Salicylic acidOrganic anion transporter 3transporter
Salicylic acidSolute carrier family 22 member 11transporter
Salicylic acidSolute carrier organic anion transporter family member 2B1transporter
Salicylic acidMonocarboxylate transporter 1transporter
Salicylic acidSolute carrier family 22 member 7transporter
Salicylic acidCytochrome P450 2C9enzyme
Salicylic acidCarbonic anhydrase 6target
Salicylic acidCarbonic anhydrase 12target
Salicylic acidCarbonic anhydrase 2target
Salicylic acidCarbonic anhydrase 4target
Salicylic acidCarbonic anhydrase 1target
VibegronBeta-3 adrenergic receptortarget
VibegronCytochrome P450 3A4enzyme
VibegronATP-dependent translocase ABCB1transporter