Intestinal Antiinfectives

Name
Intestinal Antiinfectives
Accession Number
DBCAT002401
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
Amphotericin BAn antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis.
StreptomycinAn aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis infections.
RifaximinA rifamycin-based non-systemic antibiotic used for the treatment of gastrointestinal bacterial infections, such as traveler's diarrhea and irritable bowel syndrome, and reduction of overt hepatic encephalopathy recurrence in adults.
ParomomycinAn aminoglycoside antibiotic used in the treatment of acute and chronic intestinal amebiasis, and as an adjunct for the management of hepatic coma.
FidaxomicinA macrolide antibiotic used to treat diarrhea associated with Clostridium difficile infection.
PhthalylsulfathiazoleA sulfonamide antibacterial indicated in the treatment of gastrointestinal infections.
AcetarsolAn anti infective used to treat a wide variety of infections in the body.
NifurzideNot Annotated
BroxyquinolineNot Annotated
SuccinylsulfathiazoleNot Annotated
SulfaguanidineNot Annotated
NifuroxazideAn antibiotic indicated in the treatment of susceptible gastrointestinal infections.
VancomycinA glycopeptide antibiotic used to treat severe but susceptible bacterial infections such as MRSA (methicillin-resistant Staphylococcus aureus) infections.
NystatinA polyene ionophore antifungal used to treat cutaneous, mucocutaneous, and gastrointestinal mycotic infections, particularly those caused by Candida species.
ColistinA polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria.
NatamycinA macrolide antifungal used to treat fungal infections of the eye.
NeomycinAn aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body.
KanamycinAn aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria.
Polymyxin BA polymyxin antibiotic used to treat a wide variety of infections in the body.
MiconazoleAn azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.
RifamycinAn antibacterial used to treat traveler's diarrhea.
Drugs & Drug Targets
DrugTargetType
Amphotericin BErgosteroltarget
Streptomycin30S ribosomal protein S12target
Streptomycin16S ribosomal RNAtarget
StreptomycinProtein-arginine deiminase type-4target
Streptomycin23S ribosomal RNAtarget
StreptomycinBacterial outer membranetarget
StreptomycinCytoplasmic membranetarget
RifaximinDNA-directed RNA polymerase subunit betatarget
RifaximinNuclear receptor subfamily 1 group I member 2target
RifaximinCytochrome P450 3A4enzyme
RifaximinCytochrome P450 2C19enzyme
RifaximinCytochrome P450 2C8enzyme
Paromomycin16S ribosomal RNAtarget
Paromomycin30S ribosomal protein S10target
FidaxomicinP-glycoprotein 1transporter
FidaxomicinRNA polymerase sigma factortarget
FidaxomicinCytochrome P450 3A4enzyme
VancomycinD-Ala-D-Ala moiety of NAM/NAG peptide subunits of peptidoglycantarget
VancomycinSerum albumincarrier
Vancomycinalpha1-acid glycoproteincarrier
VancomycinHistamine H1 receptorcarrier
NystatinErgosteroltarget
NystatinSolute carrier organic anion transporter family member 1B1transporter
NystatinSolute carrier organic anion transporter family member 1B3transporter
ColistinBacterial outer membranetarget
NatamycinErgosteroltarget
Neomycin30S ribosomal protein S12target
Neomycin16S ribosomal RNAtarget
NeomycinExtracellular calcium-sensing receptortarget
Kanamycin30S ribosomal protein S12target
Kanamycin16S ribosomal RNAtarget
KanamycinAminoglycoside 2'-N-acetyltransferaseenzyme
KanamycinKanamycin nucleotidyltransferaseenzyme
KanamycinAminoglycoside 3'-phosphotransferaseenzyme
Polymyxin BBacterial outer membranetarget
Polymyxin BSolute carrier family 15 member 2transporter
MiconazoleCytochrome P450 2C9enzyme
MiconazoleCytochrome P450 2D6enzyme
MiconazoleCytochrome P450 3A4enzyme
MiconazoleP-glycoprotein 1transporter
MiconazoleCytochrome P450 51target
MiconazoleNitric oxide synthase, endothelialtarget
MiconazoleNitric oxide synthase, inducibletarget
MiconazoleCytochrome P450 11B1, mitochondrialenzyme
MiconazoleCytochrome P450 2A6enzyme
MiconazoleCytochrome P450 2B6enzyme
MiconazoleCytochrome P450 2C19enzyme
MiconazoleCytochrome P450 2E1enzyme
MiconazoleNuclear receptor subfamily 1 group I member 2target
MiconazoleLanosterol 14-alpha demethylaseenzyme
MiconazoleCytochrome P450 19A1enzyme
MiconazoleCalcium-activated potassium channeltarget
MiconazoleVoltage-gated Potassium Channelstarget
MiconazoleInward rectifier potassium channeltarget
MiconazoleVoltage gated L-type calcium channeltarget
MiconazoleSerum albumincarrier
MiconazoleCytochrome P450 2C8enzyme
RifamycinCytochrome P450 3A4enzyme
RifamycinCytochrome P450 2C19enzyme
RifamycinCytochrome P450 2B6enzyme
RifamycinCytochrome P450 2C8enzyme
RifamycinCytochrome P450 2C9enzyme
RifamycinSolute carrier organic anion transporter family member 1A2transporter
RifamycinSolute carrier organic anion transporter family member 1B1transporter
RifamycinSolute carrier organic anion transporter family member 1B3transporter
RifamycinSolute carrier organic anion transporter family member 2A1transporter
RifamycinSolute carrier organic anion transporter family member 2B1transporter
RifamycinSerum albumincarrier
RifamycinDNA-directed RNA polymerase subunit betatarget
RifamycinDNA-directed RNA polymerase subunit alphatarget
RifamycinDNA-directed RNA polymerase subunit beta'target
RifamycinMultidrug and toxin extrusion protein 1transporter
RifamycinCytochrome P450 1A2enzyme
RifamycinP-glycoprotein 1transporter
RifamycinCytochrome P450 2D6enzyme