Potential QTc-Prolonging Agents

Name
Potential QTc-Prolonging Agents
Accession Number
DBCAT002691
Description

Agents associated with a possible risk of QTc prolongation.

Drugs
DrugDrug Description
OctreotideA peptide drug used to treat acromegaly as well as diarrhea associated with metastatic carcinoid tumors and vasoactive intestinal peptide secreting tumors.
OxytocinA recombinant hormone used to induce or strengthen uterine contractions in pregnant women to aid in labor and delivery or to control postpartum bleeding.
BortezomibA proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies.
FluconazoleA triazole antifungal used to treat various fungal infections including candidiasis.
NelfinavirA viral protease inhibitor used in the treatment of HIV infection.
IsradipineA dihydropyridine calcium channel blocker used for the treatment of hypertension.
VenlafaxineA selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression.
AtomoxetineA selective norepinephrine reuptake inhibitor (SNRI) used in the management of Attention Deficit Hyperactivity Disorder (ADHD).
OlanzapineAn antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders.
ProtriptylineA tricyclic antidepressant that is indicated in the treatment of depression only under close clinical supervision.
AlfuzosinAn alpha-1 adrenergic antagonist used in the management of benign prostatic hypertrophy (BPH).
MefloquineAn antimalarial agent used as a schizonticidal agent.
MirtazapineA tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite.
TreprostinilA prostacyclin vasodilator for the treatment of pulmonary arterial hypertension to relieve exercise associated symptoms and to prevent clinical deterioration after stopping epoprostenol.
SorafenibA kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma.
RitonavirAn HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
FoscarnetAn antiviral used to treat CMV, HIV, and HSV infections.
NortriptylineA tricyclic antidepressant used in the treatment of depression.
AmoxapineA tricyclic antidepressant used in the treatment of neurotic or reactive depressive disorders and endogenous or psychotic depression.
HydroxyzineAn antihistamine used to treat anxiety and tension associated with psychoneuroses, as well as allergic conditions such as pruritus and chronic urticaria.
VoriconazoleA triazole compound used to treat fungal infections.
NicardipineA calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina.
TrazodoneA serotonin uptake inhibitor used to treat major depressive disorder.
GalantamineA cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease.
TamoxifenA selective estrogen receptor modulator used to treat estrogen receptor positive breast cancer, reduce the risk of invasive breast cancer following surgery, or reduce the risk of breast cancer in high risk women.
MoexiprilAn angiotensin converting enzyme inhibitor prodrug used to treat hypertension.
TizanidineAn alpha-2 adrenergic agonist used for the short-term treatment of muscle spasticity.
IbandronateA bisphosphonate used to treat osteoporosis in postmenopausal women.
ApomorphineA morphine derivative D2 dopamine agonist used to treat hypomobile "off" episodes of advanced Parkinson's disease.
TrimipramineA tricyclic antidepressant used to treat depression.
RisperidoneA second-generation antipsychotic medication used to treat a number of mental health disorders including schizophrenia, bipolar mania, psychosis, or as an adjunct in severe depression.
IsofluraneAn inhaled general anesthetic used in surgery.
IndapamideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure.
PropofolA medication used in general anesthesia and for sedation.
VardenafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction.
TerbutalineA beta-2 adrenergic agonist used as a bronchodilator and to prevent premature labor.
AmantadineA medication used to treat dyskinesia in Parkinson's patients receiving levodopa, as well as extrapyramidal side effects of medications.
MetronidazoleA nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
FamotidineA histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome.
MaprotilineA tetracyclic antidepressant used to treat depressive illness, major depressive disorder, bipolar disorder, and anxiety associated with depression.
SalmeterolA long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD.
FelbamateAn anticonvulsant used to treat severe epilepsy.
FormoterolAn inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD.
SalbutamolA beta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms.
SulfamethoxazoleAn oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract.
KetoconazoleA broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
TolterodineA muscarinic receptor antagonist used to treat overactive bladder with urinary incontinence, urgency, and frequency.
NorfloxacinA broad-spectrum fluoroquinolone antibiotic with variable activity against gram-positive and gram-negative bacteria. Typically reserved for the treatment of UTIs due to accumulation in the urine.
PromethazineA first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness.
AtazanavirAn antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV.
DiphenhydramineA H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.
DoxepinA psychotropic agent used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia.
DesipramineA tricyclic antidepressant used in the treatment of depression.
ItraconazoleAn antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis.
DesfluraneA general inhalation anesthetic for inpatient and outpatient surgery in adults.
MetoclopramideAn antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying.
SevofluraneA inhalation anaesthetic agent used for induction and maintenance of general anesthesia during surgical procedures.
AripiprazoleAn atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome.
DasatinibA tyrosine kinase inhibitor used for the treatment of lymphoblastic or chronic myeloid leukemia with resistance or intolerance to prior therapy.
LapatinibAn antineoplastic agent and tyrosine kinase inhibitor used for the treatment of advanced or metastatic HER-negative breast cancer in patients who received prior chemotherapeutic treatments.
PosaconazoleA triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
SunitinibA receptor tyrosine kinase inhibitor and chemotherapeutic agent used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).
ArformoterolA beta-2 adrenergic agonist and bronchodilator used for long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.
MethotrimeprazineA phenothiazine used in the management of psychosis, particular those of schizophrenia, and manic phases of bipolar disorder.
SolifenacinA muscarinic antagonist with antispasmodic properties used to treat urge urinary incontinence, urgency, and urinary frequency associated with an overactive bladder.
ThiothixeneAn antipsychotic indicated for the management of schizophrenia.
VorinostatA histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies.
EzogabineAn antiepileptic agent used as an adjuvant treatment of partial-onset seizures.
IndacaterolAn inhaled long-acting beta-2 adrenergic agonist used to relax bronchial smooth muscle and improve symptoms and airflow obstruction caused by Chronic Obstructive Pulmonary Disease (COPD) and moderate to severe asthma.
PasireotideA somatostatin analog used in the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery is not appropriate.
DegarelixA GnRH receptor antagonist used in the management of advanced prostate cancer.
BuserelinA LHRH agonist used for the palliative treatment of hormone-dependent advanced carcinoma of the prostate gland in males and treatment of endometriosis in females.
HistrelinA GnRH agonist found in subcutaneous implants used for the treatment of pediatric patients with central precocious puberty and the palliative treatment of advanced prostate cancer.
TriptorelinA GnRH agonist indicated for the palliative treatment of advanced prostate cancer.
RilpivirineA non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1).
EribulinA microtubule inhibitor used to treat metastatic breast cancer and metastatic or unresectable liposarcoma.
MirabegronA beta-3 adrenergic agonist used to treat urge urinary incontinence, urinary frequency and urgency associated with overactive bladder (OAB).
DabrafenibA kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
OlodaterolA long-acting beta2-adrenergic agonist used in the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
VilanterolA long-acting beta2-adrenergic agonist used in combination with other bronchodilators for the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
MequitazineFor the treatment of Hay fever, urticaria (hives) and allergic rhinitis
AmodiaquineFor treatment of acute malarial attacks in non-immune subjects.
CUDC-907CUDC-907 has been used in trials studying the treatment of Lymphoma, Solid Tumors, BREAST CANCER, Multiple Myeloma, and NUT Midline Carcinoma, among others.
GivinostatGivinostat has been used in trials studying the treatment of Polycythemia Vera, Juvenile Idiopathic Arthritis, Duchenne Muscular Dystrophy (DMD), Chronic Myeloproliferative Neoplasms, and Polyarticular Course Juvenile Idiopathic Arthritis.
TandutinibInvestigated for use/treatment in leukemia (myeloid).
DifloxacinDifloxacin is a synthetic fluoroquinolone used in veterinary. As an antibacterial, it presents a broad bactericidal spectrum and its effects are dependent on its concentration. However, it presents a reduced...
EnoxacinFor the treatment of adults (≥18 years of age) with the following infections caused by susceptible strains of the designated microorganisms: (1) uncomplicated urethral or cervical gonorrhea due to Neisseria...
FleroxacinFleroxacin is a broad-spectrum antimicrobial fluoroquinolone.
FlumequineFlumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections.
OrbifloxacinOrbifloxacin is a fluoroquinolone antibiotic. It is marketed by Schering-Plough Animal Health and approved for certain infections in dogs.
Oxolinic acidNot Annotated
PazufloxacinPazufloxacin is under investigation in clinical trial NCT02592096 (Pazufloxacin Mesilate Ear Drops Clinical Trial Protocol).
PefloxacinFor the treatment of uncomplicated gonococcal urethritis in males and for gram-negative-bacterial infections in the gastrointestinal system and the genitourinary tract.
Pipemidic acidNot Annotated
Piromidic acidNot Annotated
PrulifloxacinPrulifloxacin has been investigated for the treatment of Urinary Tract Infection.
RosoxacinFor the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients.
RufloxacinRufloxacin is a quinolone antibiotic.
SarafloxacinSarafloxacin is a quinolone antibiotic drug, which was discontinued by its manufacturer, Abbott Laboratories, before receiving approval for use in the US or Canada.
CilostazolAn antiplatelet agent and vasodilator used for the symptomatic relief of intermittent claudication.
GatifloxacinA fourth generation fluoroquinolone used to treat a wide variety of infections in the body.
HydroxychloroquineAn antimalarial medication used to treat uncomplicated cases of malaria and for chemoprophylaxis in specific regions. Also a disease modifying anti-rheumatic drug (DMARD) indicated for treatment of rheumatoid arthritis and lupus erythematosus.
AcrivastineAn antihistamine agent used for the symptomatic relief of seasonal allergic rhinitis such as sneezing, rhinorrhea, pruritus, lacrimation, and nasal congestion.
AlcaftadineA H1 histamine receptor antagonist for ophthalmic use to prevent itching associated with allergic conjunctivitis.
AlimemazineAn antihistamine agent used to prevent and relieve allergic conditions which cause pruritus and other allergic skin conditions, including urticaria.
Aripiprazole lauroxilAn antipsychotic used to treat schizophrenia in adults.
AzatadineAn H1 receptor antagonist used to treat perennial and allergic rhinitis as well as eustachian tube congestion.
BenzatropineAn anticholinergic drug used to treat Parkinson's disease (PD) and extrapyramidal symptoms, except tardive dyskinesia.
BilastineA peripheral histamine H1-antagonist used to treat seasonal allergic rhinitis and chronic spontaneous urticaria.
BuclizineFor prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems).
CetirizineA selective Histamine-1 antagonist drug used in allergic rhinitis and chronic urticaria.
ChlorcyclizineChlorcyclizine is a first generation phenylpiperazine class antihistamine used to treat urticaria, rhinitis, pruritus, and other allergy symptoms. Chlorcyclizine also has some local anesthetic, anticholinergic, and antiserotonergic properties, and can...
ChlorprothixeneFor treatment of psychotic disorders (e.g. schizophrenia) and of acute mania occuring as part of bipolar disorders.
CyclizineAn antihistamine and antiemetic drug used for the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo.
CyproheptadineA serotonin and histamine antagonist used in the treatment of allergy symptoms and in combination with epinephrine in the treatment of anaphylaxis.
DexbrompheniramineAn antihistamine used to treat allergy symptoms including upper respiratory tract symptoms.
DosulepinIndicated in the treatment of symptoms of depressive illness, especially where an anti-anxiety effect is required.
DoxylamineAn antihistamine used to treat insomnia and allergy symptoms and is used with pyridoxine in the treatment of nausea and vomiting in pregnancy.
EbastineEbastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria.
EpinastineAn H1 receptor antagonist used to prevent itching in allergic conjunctivitis.
KetotifenA histamine H1 receptor blocker used to treat mild asthma and allergic conjunctivitis.
LevocabastineA selective histamine H1 receptor antagonist indicated for the management of seasonal allergic conjunctivitis symptoms.
LevocetirizineAn H1-receptor antagonist used to treat symptoms associated with chronic allergic rhinitis and uncomplicated cases of chronic idiopathic urticaria.
MepyramineAn antihistamine agent used for the symptomatic treatment of allergy, hypersensitivity reactions, and pruritic skin disorders.
OrphenadrineA muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort.
PheniramineAn antihistamine used to treat allergic rhinitis and pruritus.
RupatadineA selective histamine H1 receptor antagonist and platelet activating factor (PAF) antagonist used to treat allergic rhinitis.
TriprolidineA sedating antihistamine combined with pseudoephedrine and guaifenesin in various types of cold and allergy medications to relieve allergy symptoms, hay fever and common cold symptoms, and to aid in sleep.
BrompheniramineA histamine H1 antagonist used to treat coughs, upper respiratory symptoms, and nasal congestion associated with allergies and the common cold.
AcetyldigoxinNot Annotated
AjmalineFor use as an antiarrhythmic agent.
AnisodamineAnisodamine has been investigated for the treatment of Intestinal Diseases.
AranidipineAranidipine has been used for many years to treat angina pectoris and hypertension.
BencyclaneA vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels.
BretyliumA norepinephrine release inhibitor used for the prophylaxis and therapy of ventricular fibrillation, as well as the treatment of life-threatening ventricular arrhythmias.
BupranololUsed to manage hypertension and tachycardia. Also used to treat glaucoma.
CariporideInvestigated for use/treatment in cardiac surgery.
CarteololA beta adrenergic antagonist used to treat arrhythmia, angina, hypertension, and glaucoma.
CeliprololCeliprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris.
CibenzolineNot Annotated
CicletanineCicletanine is under investigation for the treatment of Diabetes, Hypokalemia, Hyponatremia, and Arterial Hypertension.
DigoxinA cardiac glycoside used in the treatment of mild to moderate heart failure and for ventricular response rate control in chronic atrial fibrillation.
DigitoxinA cardiac glycoside used in the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.
EfonidipineFor the treatment of hypertension.
EncainideA voltage-gated sodium channel blocker used for management of atrial or ventricular fibrillation, atrial flutter, and ventricular tachycardia, that is no longer used due to proarrhythmic adverse effects.
EsmololA cardioselective beta-adrenergic blocker used for the short-term control of ventricular rate and heart rate in various types of tachycardia, including perioperative tachycardia and hypertension.
EthosuximideAn anticonvulsant used to treat petit mal seizures.
FelodipineA calcium channel blocker used to treat hypertension.
GallopamilGallopamil has been used in trials studying the treatment of Asthma.
HyoscyamineFor treatment of bladder spasms, peptic ulcer disease, diverticulitis, colic, irritable bowel syndrome, cystitis, and pancreatitis. Also used to treat certain heart conditions, to control the symptoms of Parkinson's disease...
IndenololIndenolol is a drug of the beta-adrenergic blocker class.
LacidipineIndicated for the treatment of hypertension either alone or in combination with other antihypertensive agents, including β-adrenoceptor antagonists, diuretics, and ACE-inhibitors .
LamotrigineA phenyltriazine antiepileptic used to treat some types of epilepsy and bipolar I disorder.
LidoflazineNot Annotated
LorajmineNot Annotated
LosartanAn angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke.
LevomentholAn organic compound used to treat mild to moderate muscle and joint pain.
MethsuximideA succinimide anticonvulsant that increases the seizure threshold. Primarily used for childhood absence seizures. Functions by suppressing paroxysmal spike-and-wave patterns associated with lapses of consciousness in absence seizures.
MoricizineAn antiarrhythmic used to treat arrhythmias.
NiguldipineNiguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties.
NitrendipineFor the treatment of mild to moderate hypertension
PerhexilineFor the management of severe angina pectoris.
PilsicainidePilsicainide has been investigated for the treatment of Paroxysmal Atrial Fibrillation.
PinaveriumA spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and functional disorders of the biliary tract.
PrajmalineNot Annotated
PregabalinAn anticonvulsant drug used to treat neuropathic pain conditions and fibromyalgia, and for the treatment of partial onset seizures in combination with other anticonvulsants.
TalinololTalinolol has been investigated for the basic science of Gastrointestinal Motility Disorder.
TetrahydropalmatineTetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity).
TimololA non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma.
TrimebutineA spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery.
TrimethadioneAn anticonvulsant agent indicated for the control of treatment-refractory petit mal seizures.
VernakalantAn antiarrhythmic medication used to treat patients with atrial fibrillation.
ZonisamideA sulfonamide anticonvulsant used to treat partial seizures.
LurasidoneAn atypical antipsychotic used to treat schizophrenia and depressive episodes associated with bipolar I disorder.
InotersenAn antisense oligonucleotide used to treat polyneuropathy of hereditary transthyretin-mediated amyloidosis.
AmisulprideInvestigated for use/treatment in schizophrenia and schizoaffective disorders, mania in bipolar disorder, and depression.
DisulfiramA carbamate derivative used to treat alcohol addiction.
HydrochlorothiazideA thiazide diuretic used to treat edema associated with a number of conditions, and hypertension.
DelafloxacinA fluoroquinolone antibiotic used to treat skin and skin structure infections.
Farnesyl thiopyrophosphateNot Available
EchothiophateAn acetylcholinesterase inhibitor used in ophthalmic preparations to increase the drainage of intraocular fluid; most commonly used for the treatment of glaucoma.
MalathionA parasympathomimetic organophosphate used to treat head lice.
Farnesyl diphosphateNot Available
Geranylgeranyl diphosphateNot Available
CoumaphosThis drug is a fat-soluble phosphorothioate agent that kills both insects and mites. It is non-volatile in nature and is well known by a variety of names as such a...
DichlorvosDichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the organophosphate class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products...
FamphurNot Annotated
FenthionFenthion is an organothiophosphate drug used as an insecticide, avicide, and acaricide. Its mode of action is explained by cholinesterase enzyme inhibition, which is similar to other organophosphates. Fenthion is...
PhosmetPhosmet is a phthalimide-derived organophosphate. It is a non-specific insecticide. It is mainly used on apple trees to control codling moths. It is also used on other fruit crops, ornamentals,...
TemefosDiphos has been used in trials studying the treatment of Plasmodium Falciparum Malaria.
TacrolimusA calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis.
TriclabendazoleAn anthelmintic drug used to treat fascioliasis.
LopinavirAn HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection.
ClofazimineA riminophenazine antimycobacterial used to treat leprosy.
FostemsavirAn antiretroviral HIV-1 attachment inhibitor targeted against the gp120 subunit within the HIV-1 gp160 envelope glycoprotein.
Drugs & Drug Targets
DrugTargetType
OctreotideMyeloperoxidaseenzyme
OctreotideCytochrome P450 3A4enzyme
OctreotideSomatostatin receptortarget
OctreotideSerum albumincarrier
OctreotideP-glycoprotein 1transporter
OctreotideCanalicular multispecific organic anion transporter 1transporter
OxytocinOxytocin-neurophysin 1target
OxytocinOxytocin receptortarget
OxytocinProlyl endopeptidaseenzyme
BortezomibCytochrome P450 3A4enzyme
BortezomibCytochrome P450 2C19enzyme
BortezomibCytochrome P450 1A2enzyme
BortezomibCytochrome P450 2D6enzyme
BortezomibCytochrome P450 2C9enzyme
BortezomibProteasome subunit beta type-5target
BortezomibProteasome subunit beta type-1target
BortezomibP-glycoprotein 1transporter
BortezomibSolute carrier organic anion transporter family member 1B3transporter
FluconazoleCytochrome P450 3A4enzyme
FluconazoleCytochrome P450 2C9enzyme
FluconazoleCytochrome P450 2C19enzyme
FluconazoleP-glycoprotein 1transporter
FluconazoleCytochrome P450 51target
FluconazoleCytochrome P450 3A5enzyme
NelfinavirHIV-1 proteasetarget
NelfinavirCytochrome P450 2C19enzyme
NelfinavirCytochrome P450 3A4enzyme
NelfinavirCytochrome P450 2B6enzyme
NelfinavirCytochrome P450 3A5enzyme
NelfinavirCytochrome P450 3A7enzyme
NelfinavirP-glycoprotein 1transporter
NelfinavirSolute carrier family 22 member 1transporter
NelfinavirSolute carrier organic anion transporter family member 1A2transporter
NelfinavirATP-binding cassette sub-family G member 2transporter
NelfinavirSolute carrier organic anion transporter family member 1B1transporter
NelfinavirCytochrome P450 2D6enzyme
NelfinavirSerum albumincarrier
NelfinavirUDP-glucuronosyltransferase 1-1enzyme
NelfinavirSolute carrier organic anion transporter family member 1B3transporter
NelfinavirSolute carrier organic anion transporter family member 2B1transporter
NelfinavirBile salt export pumptransporter
NelfinavirCytochrome P450 2C9enzyme
IsradipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
IsradipineCytochrome P450 3A4enzyme
IsradipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
IsradipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
IsradipineVoltage-dependent L-type calcium channel subunit beta-2target
IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
IsradipineBile salt export pumptransporter
VenlafaxineSodium-dependent serotonin transportertarget
VenlafaxineSodium-dependent noradrenaline transportertarget
VenlafaxineCytochrome P450 2D6enzyme
VenlafaxineCytochrome P450 3A4enzyme
VenlafaxineSodium-dependent dopamine transportertarget
VenlafaxineP-glycoprotein 1transporter
VenlafaxineATP-binding cassette sub-family G member 2transporter
AtomoxetineSodium-dependent noradrenaline transportertarget
AtomoxetineCytochrome P450 2D6enzyme
AtomoxetineSodium-dependent serotonin transportertarget
AtomoxetineCytochrome P450 2C19enzyme
AtomoxetineNMDA receptortarget
AtomoxetineSerum albumincarrier
Atomoxetinealpha1-acid glycoproteincarrier
AtomoxetineHigh affinity immunoglobulin gamma Fc receptor Icarrier
AtomoxetineG protein-activated inward rectifier potassium channel 1target
AtomoxetineKappa-type opioid receptortarget
OlanzapineDopamine D1 receptortarget
OlanzapineMuscarinic acetylcholine receptor M1target
OlanzapineMuscarinic acetylcholine receptor M3target
Olanzapine5-hydroxytryptamine receptor 2Atarget
OlanzapineDopamine D4 receptortarget
OlanzapineHistamine H1 receptortarget
OlanzapineMuscarinic acetylcholine receptor M4target
OlanzapineMuscarinic acetylcholine receptor M2target
OlanzapineDopamine D2 receptortarget
Olanzapine5-hydroxytryptamine receptor 2Ctarget
OlanzapineDopamine D3 receptortarget
OlanzapineAlpha-1B adrenergic receptortarget
OlanzapineCytochrome P450 1A2enzyme
Olanzapine5-hydroxytryptamine receptor 3Atarget
Olanzapine5-hydroxytryptamine receptor 6target
OlanzapineAlpha-1A adrenergic receptortarget
OlanzapineDopamine D5 receptortarget
OlanzapineSerum albumincarrier
OlanzapineAlpha-1-acid glycoprotein 1carrier
OlanzapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
OlanzapineCytochrome P450 2D6enzyme
OlanzapineP-glycoprotein 1transporter
OlanzapineCytochrome P450 2C19enzyme
OlanzapineD(1) dopamine receptortarget
OlanzapineBeta adrenergic receptortarget
Olanzapine5-hydroxytryptamine receptor 1target
OlanzapineGABA(A) Receptor Benzodiazepine Binding Sitetarget
OlanzapineCytochrome P450 2C9enzyme
OlanzapineUDP-glucuronosyltransferase 1-4enzyme
OlanzapineCytochrome P450 3A4enzyme
OlanzapineCytochrome P450 3A Subfamilyenzyme
ProtriptylineSodium-dependent noradrenaline transportertarget
ProtriptylineSodium-dependent serotonin transportertarget
ProtriptylineP-glycoprotein 1transporter
AlfuzosinAlpha-1A adrenergic receptortarget
AlfuzosinAlpha-1B adrenergic receptortarget
AlfuzosinAlpha-1D adrenergic receptortarget
AlfuzosinCytochrome P450 3A4enzyme
AlfuzosinPotassium voltage-gated channel subfamily H member 2target
MefloquineCholinesteraseenzyme
MefloquineCytochrome P450 3A4enzyme
MefloquineAdenosine receptor A2atarget
MefloquineFe(II)-protoporphyrin IXtarget
MefloquineP-glycoprotein 1transporter
MefloquineCytochrome P450 19A1enzyme
MefloquineAcetylcholinesteraseenzyme
Mefloquine80S ribosomal subunittarget
Mirtazapine5-hydroxytryptamine receptor 2Atarget
Mirtazapine5HT3 serotonin receptortarget
MirtazapineAlpha-2A adrenergic receptortarget
Mirtazapine5-hydroxytryptamine receptor 2Ctarget
MirtazapineKappa-type opioid receptortarget
MirtazapineHistamine H1 receptortarget
MirtazapineCytochrome P450 1A2enzyme
MirtazapineCytochrome P450 3A4enzyme
MirtazapineCytochrome P450 2D6enzyme
MirtazapineAlpha-1 adrenergic receptorstarget
MirtazapineSodium-dependent serotonin transportertransporter
TreprostinilP2Y purinoceptor 12target
TreprostinilPeroxisome proliferator-activated receptor deltatarget
TreprostinilProstacyclin receptortarget
TreprostinilCytochrome P450 2C9enzyme
SorafenibSerine/threonine-protein kinase B-raftarget
SorafenibReceptor-type tyrosine-protein kinase FLT3target
SorafenibRAF proto-oncogene serine/threonine-protein kinasetarget
SorafenibVascular endothelial growth factor receptor 3target
SorafenibPlatelet-derived growth factor receptor betatarget
SorafenibMast/stem cell growth factor receptor Kittarget
SorafenibVascular endothelial growth factor receptor 2target
SorafenibCytochrome P450 3A4enzyme
SorafenibUDP-glucuronosyltransferase 1-9enzyme
SorafenibCytochrome P450 2B6enzyme
SorafenibCytochrome P450 2C8enzyme
SorafenibCytochrome P450 3A5enzyme
SorafenibCytochrome P450 3A7enzyme
SorafenibCytochrome P450 2C9enzyme
SorafenibMultidrug resistance-associated protein 4transporter
SorafenibP-glycoprotein 1transporter
SorafenibCanalicular multispecific organic anion transporter 1transporter
SorafenibATP-binding cassette sub-family G member 2transporter
SorafenibCytochrome P450 1A2enzyme
SorafenibCytochrome P450 2C19enzyme
SorafenibCytochrome P450 2D6enzyme
SorafenibUDP-glucuronosyltransferase 1-1enzyme
SorafenibRalA-binding protein 1transporter
SorafenibFibroblast growth factor receptor 1target
SorafenibProto-oncogene tyrosine-protein kinase receptor Rettarget
SorafenibVascular endothelial growth factor receptor 1target
SorafenibSolute carrier organic anion transporter family member 1B1transporter
RitonavirHuman immunodeficiency virus type 1 proteasetarget
RitonavirCytochrome P450 2D6enzyme
RitonavirCytochrome P450 2C9enzyme
RitonavirCytochrome P450 2C19enzyme
RitonavirCytochrome P450 2B6enzyme
RitonavirCytochrome P450 2C8enzyme
RitonavirP-glycoprotein 1transporter
RitonavirMultidrug resistance-associated protein 1transporter
RitonavirCanalicular multispecific organic anion transporter 1transporter
RitonavirSolute carrier organic anion transporter family member 1A2transporter
RitonavirATP-binding cassette sub-family G member 2transporter
RitonavirSolute carrier organic anion transporter family member 1B1transporter
RitonavirCytochrome P450 1A2enzyme
RitonavirNuclear receptor subfamily 1 group I member 2target
RitonavirSerum albumincarrier
RitonavirCytochrome P450 3A4enzyme
RitonavirCytochrome P450 3A5enzyme
RitonavirCytochrome P450 3A7enzyme
RitonavirUDP-glucuronosyltransferases (UGTs)enzyme
RitonavirSolute carrier organic anion transporter family member 2B1transporter
RitonavirBile salt export pumptransporter
RitonavirAlpha-1-acid glycoprotein 1carrier
RitonavirSolute carrier organic anion transporter family member 1B3transporter
FoscarnetDNA polymerase catalytic subunittarget
FoscarnetDNA polymerase catalytic subunittarget
FoscarnetSolute carrier family 22 member 6transporter
FoscarnetMonocarboxylate transporter 1transporter
NortriptylineSodium-dependent serotonin transportertarget
NortriptylineSodium-dependent noradrenaline transportertarget
NortriptylineCytochrome P450 1A2enzyme
NortriptylineCytochrome P450 2D6enzyme
NortriptylineSerum albumincarrier
NortriptylineAlpha-1-acid glycoprotein 1carrier
NortriptylineHistamine H1 receptortarget
Nortriptyline5-hydroxytryptamine receptor 2Atarget
NortriptylineAlpha-1A adrenergic receptortarget
Nortriptyline5-hydroxytryptamine receptor 1Atarget
NortriptylineCytochrome P450 3A4enzyme
NortriptylineCytochrome P450 3A5enzyme
NortriptylineAlpha-1D adrenergic receptortarget
NortriptylineCytochrome P450 2C19enzyme
NortriptylineCytochrome P450 2E1enzyme
Nortriptyline5-hydroxytryptamine receptor 2Ctarget
NortriptylineAlpha-1B adrenergic receptortarget
NortriptylineAlpha-2 adrenergic receptorstarget
NortriptylineBeta adrenergic receptortarget
NortriptylineDopamine D2 receptortarget
NortriptylineSigma receptortarget
Nortriptyline5-hydroxytryptamine receptor 1Ctarget
NortriptylineSodium-dependent noradrenaline transportertransporter
NortriptylineMuscarinic acetylcholine receptortarget
NortriptylineP-glycoprotein 1transporter
AmoxapineSodium-dependent serotonin transportertarget
AmoxapineSodium-dependent noradrenaline transportertarget
AmoxapineAlpha-2A adrenergic receptortarget
AmoxapineDopamine D2 receptortarget
AmoxapineAlpha-1A adrenergic receptortarget
AmoxapineDopamine D1 receptortarget
AmoxapineMuscarinic acetylcholine receptor M1target
AmoxapineGamma-aminobutyric acid receptor subunit alpha-1target
AmoxapineAlpha-1-acid glycoprotein 1carrier
AmoxapineCytochrome P450 2D6enzyme
Amoxapine5-hydroxytryptamine receptor 2Atarget
Amoxapine5-hydroxytryptamine receptor 2Ctarget
Amoxapine5-hydroxytryptamine receptor 6target
Amoxapine5-hydroxytryptamine receptor 7target
AmoxapineDopamine D3 receptortarget
AmoxapineDopamine D4 receptortarget
AmoxapineHistamine H1 receptortarget
AmoxapineAlpha-1 adrenergic receptorstarget
AmoxapineMuscarinic acetylcholine receptortarget
Amoxapine5-hydroxytryptamine receptor 2Btarget
Amoxapine5-hydroxytryptamine receptor 3Atarget
Amoxapine5-hydroxytryptamine receptor 1Atarget
Amoxapine5-hydroxytryptamine receptor 1Btarget
AmoxapineAlpha-2 adrenergic receptorstarget
AmoxapineHistamine H4 receptortarget
AmoxapineGABA(A) Receptortarget
AmoxapineSodium-dependent dopamine transportertarget
HydroxyzineHistamine H1 receptortarget
HydroxyzineCytochrome P450 2D6enzyme
HydroxyzineCytochrome P450 3A4enzyme
HydroxyzineCytochrome P450 3A5enzyme
HydroxyzinePotassium voltage-gated channel subfamily H member 2target
HydroxyzineP-glycoprotein 1transporter
HydroxyzineSerum albumincarrier
VoriconazoleCytochrome P450 2C19enzyme
VoriconazoleCytochrome P450 3A4enzyme
VoriconazoleCytochrome P450 2C9enzyme
VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
VoriconazoleCytochrome P450 3A5enzyme
VoriconazoleCytochrome P450 3A7enzyme
VoriconazoleProstaglandin G/H synthase 1enzyme
VoriconazoleCytochrome P450 51target
VoriconazoleCytochrome P450 2B6enzyme
NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NicardipineCytochrome P450 3A4enzyme
NicardipineCytochrome P450 2C19enzyme
NicardipineCytochrome P450 2C8enzyme
NicardipineCytochrome P450 2D6enzyme
NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
NicardipineAlpha-1A adrenergic receptortarget
NicardipineAlpha-1D adrenergic receptortarget
NicardipineAlpha-1B adrenergic receptortarget
NicardipineMuscarinic acetylcholine receptor M1target
NicardipineMuscarinic acetylcholine receptor M2target
NicardipineMuscarinic acetylcholine receptor M3target
NicardipineMuscarinic acetylcholine receptor M4target
NicardipineMuscarinic acetylcholine receptor M5target
NicardipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
NicardipineVoltage-dependent L-type calcium channel subunit beta-2target
NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NicardipineCalmodulintarget
NicardipineP-glycoprotein 1transporter
NicardipineCytochrome P450 2B6enzyme
NicardipineCytochrome P450 2E1enzyme
NicardipineCytochrome P450 3A5enzyme
NicardipineSolute carrier organic anion transporter family member 1B1transporter
NicardipineBile salt export pumptransporter
NicardipineCytochrome P450 2C9enzyme
Trazodone5-hydroxytryptamine receptor 2Atarget
TrazodoneSodium-dependent serotonin transportertarget
TrazodoneAlpha-1A adrenergic receptortarget
TrazodoneAlpha-2A adrenergic receptortarget
TrazodoneHistamine H1 receptortarget
Trazodone5-hydroxytryptamine receptor 1Atarget
TrazodoneCytochrome P450 2D6enzyme
TrazodoneCytochrome P450 3A4enzyme
Trazodone5-hydroxytryptamine receptor 2Ctarget
TrazodoneCytochrome P450 3A5enzyme
TrazodoneCytochrome P450 3A7enzyme
TrazodoneP-glycoprotein 1transporter
Trazodone5-hydroxytryptamine receptor 1Ctarget
GalantamineAcetylcholinesterasetarget
GalantamineCytochrome P450 3A4enzyme
GalantamineCytochrome P450 2D6enzyme
GalantamineCholinesterasetarget
GalantamineP-glycoprotein 1transporter
GalantamineNeuronal acetylcholine receptor subunit alpha-7target
GalantamineMuscle nicotinic acetylcholine receptortarget
TamoxifenEstrogen receptor alphatarget
TamoxifenEstrogen receptor betatarget
TamoxifenCytochrome P450 2C9enzyme
TamoxifenCytochrome P450 3A4enzyme
TamoxifenCytochrome P450 2D6enzyme
TamoxifenCytochrome P450 2C8enzyme
TamoxifenCytochrome P450 2B6enzyme
TamoxifenLiver carboxylesterase 1enzyme
TamoxifenCytochrome P450 3A5enzyme
TamoxifenCytochrome P450 1A1enzyme
TamoxifenCytochrome P450 1B1enzyme
TamoxifenCytochrome P450 2C19enzyme
TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
TamoxifenCytochrome P450 3A7enzyme
TamoxifenP-glycoprotein 1transporter
TamoxifenATP-binding cassette sub-family G member 2transporter
TamoxifenCytochrome P450 19A1enzyme
TamoxifenCytochrome P450 2A6enzyme
TamoxifenCytochrome P450 2E1enzyme
TamoxifenUDP-glucuronosyltransferase 1-10enzyme
TamoxifenSulfotransferase 1A1enzyme
TamoxifenCanalicular multispecific organic anion transporter 1transporter
Tamoxifen3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerasetarget
TamoxifenProtein kinase Ctarget
TamoxifenAndrogen receptortarget
TamoxifenPotassium voltage-gated channel subfamily H member 2target
TamoxifenNuclear receptor subfamily 1 group I member 2target
TamoxifenEstrogen-related receptor gammatarget
TamoxifenSex hormone-binding globulintarget
TamoxifenBile salt export pumptransporter
TamoxifenThyroxine-binding globulincarrier
TamoxifenBile salt sulfotransferaseenzyme
TamoxifenCytochrome P450 1A2enzyme
TamoxifenUDP-glucuronosyltransferase 2B7enzyme
TamoxifenUDP-glucuronosyltransferase 2B17enzyme
TamoxifenEstrogen sulfotransferaseenzyme
TamoxifenATP-binding cassette sub-family A member 1transporter
TamoxifenMitogen-activated protein kinase 8target
TamoxifenSerum albumincarrier
MoexiprilAngiotensin-converting enzymetarget
MoexiprilSolute carrier family 15 member 1transporter
MoexiprilSolute carrier family 15 member 2transporter
TizanidineAlpha-2 adrenergic receptorstarget
TizanidineCytochrome P450 1A2enzyme
TizanidineNischarintarget
TizanidineAlpha-1 adrenergic receptorstarget
IbandronateFarnesyl pyrophosphate synthasetarget
IbandronateHydroxylapatitetarget
IbandronateGeranylgeranyl pyrophosphate synthasetarget
ApomorphineDopamine D2 receptortarget
ApomorphineDopamine D1 receptortarget
ApomorphineDopamine D4 receptortarget
ApomorphineDopamine D3 receptortarget
ApomorphineDopamine D5 receptortarget
ApomorphineAlpha-2C adrenergic receptortarget
ApomorphineAlpha-2B adrenergic receptortarget
Apomorphine5-hydroxytryptamine receptor 2Ctarget
Apomorphine5-hydroxytryptamine receptor 1Atarget
Apomorphine5-hydroxytryptamine receptor 2Atarget
Apomorphine5-hydroxytryptamine receptor 2Btarget
ApomorphineAlpha-2A adrenergic receptortarget
Apomorphine5-hydroxytryptamine receptor 1Dtarget
Apomorphine5-hydroxytryptamine receptor 1Btarget
ApomorphineCatechol O-methyltransferaseenzyme
ApomorphineSulfotransferase 1A1enzyme
ApomorphineSulfotransferase 1A2enzyme
ApomorphineSulfotransferase 1A3/1A4enzyme
ApomorphineEstrogen sulfotransferaseenzyme
ApomorphineSulfotransferase family cytosolic 1B member 1enzyme
ApomorphineCytochrome P450 2B6enzyme
ApomorphineCytochrome P450 2C8enzyme
ApomorphineCytochrome P450 3A4enzyme
ApomorphineCytochrome P450 3A5enzyme
ApomorphineUDP-glucuronosyltransferases (UGTs)enzyme
ApomorphineSerum albumincarrier
ApomorphineSynaptic vesicular amine transportertransporter
TrimipramineSodium-dependent serotonin transportertarget
TrimipramineSodium-dependent noradrenaline transportertarget
TrimipramineCytochrome P450 2D6enzyme
TrimipramineSodium-dependent dopamine transportertarget
Trimipramine5-hydroxytryptamine receptor 2Atarget
Trimipramine5-hydroxytryptamine receptor 1Atarget
TrimipramineAlpha-1A adrenergic receptortarget
TrimipramineAlpha-1B adrenergic receptortarget
TrimipramineDopamine D2 receptortarget
TrimipramineAlpha-2B adrenergic receptortarget
TrimipramineHistamine H1 receptortarget
TrimipramineCytochrome P450 2C19enzyme
TrimipramineP-glycoprotein 1transporter
TrimipramineCytochrome P450 2C9enzyme
Trimipramine5-hydroxytryptamine receptor 2Ctarget
Trimipramine5-hydroxytryptamine receptor 3Atarget
Trimipramine5-hydroxytryptamine receptor 1Dtarget
TrimipramineAlpha-2A adrenergic receptortarget
TrimipramineD(1) dopamine receptortarget
TrimipramineBeta adrenergic receptortarget
TrimipramineMuscarinic acetylcholine receptortarget
Trimipramine5-hydroxytryptamine receptor 1Ctarget
RisperidoneCytochrome P450 2D6enzyme
RisperidoneCytochrome P450 3A4enzyme
RisperidoneP-glycoprotein 1transporter
RisperidoneSerum albumincarrier
RisperidoneAlpha-1-acid glycoprotein 1carrier
Risperidone5-hydroxytryptamine receptor 2Atarget
RisperidoneDopamine D2 receptortarget
RisperidoneAlpha-1B adrenergic receptortarget
RisperidoneAlpha-2B adrenergic receptortarget
RisperidoneAlpha-1A adrenergic receptortarget
RisperidoneAlpha-2C adrenergic receptortarget
RisperidoneHistamine H1 receptortarget
Risperidone5-hydroxytryptamine receptor 2Ctarget
Risperidone5-hydroxytryptamine receptor 1Dtarget
Risperidone5-hydroxytryptamine receptor 1Atarget
Risperidone5-hydroxytryptamine receptor 7target
RisperidoneD(2L) dopamine receptortarget
RisperidoneDopamine D1 receptortarget
IsofluraneCalcium-transporting ATPase type 2C member 1target
IsofluraneATP synthase subunit delta, mitochondrialtarget
IsofluraneGamma-aminobutyric acid receptor subunit alpha-1target
IsofluranePotassium voltage-gated channel subfamily A member 1target
IsofluraneGlutamate receptor 1target
IsofluraneGlycine receptor subunit alpha-1target
IsofluraneCalmodulintarget
IsofluraneCytochrome P450 2E1enzyme
IsofluraneSerum albumincarrier
IsofluraneCytochrome P450 2B6enzyme
IsofluraneNADH-ubiquinone oxidoreductase chain 1enzyme
IsofluraneGABA(A) Receptortarget
IsofluraneNeuronal acetylcholine receptor subunit alpha-4target
IsofluraneNeuronal acetylcholine receptor subunit beta-2target
IndapamideCytochrome P450 3A4enzyme
IndapamideSolute carrier family 12 member 3target
IndapamideEpoxide hydrolase 1enzyme
Indapamidealpha1-acid glycoproteincarrier
IndapamideSerum albumincarrier
IndapamideErythrocytecarrier
PropofolCytochrome P450 2B6enzyme
PropofolUDP-glucuronosyltransferase 1-1enzyme
PropofolUDP-glucuronosyltransferase 1-9enzyme
PropofolGamma-aminobutyric acid receptor subunit beta-2target
PropofolGamma-aminobutyric acid receptor subunit beta-3target
PropofolSerum albumincarrier
PropofolSodium channel protein type 4 subunit alphatarget
PropofolSodium channel protein type 2 subunit alphatarget
PropofolFatty-acid amide hydrolase 1enzyme
PropofolCytochrome P450 2C9enzyme
PropofolUDP-glucuronosyltransferase 1-8enzyme
PropofolCytochrome P450 2E1enzyme
PropofolCytochrome P450 1B1enzyme
PropofolCytochrome P450 1A1enzyme
PropofolCytochrome P450 1A2enzyme
PropofolCytochrome P450 2C18enzyme
PropofolCytochrome P450 2C19enzyme
PropofolCytochrome P450 2C8enzyme
PropofolUDP-glucuronosyltransferase 1-6enzyme
PropofolGABA(A) Receptortarget
PropofolP-glycoprotein 1transporter
VardenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
VardenafilCytochrome P450 3A4enzyme
VardenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
VardenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
VardenafilCytochrome P450 3A5enzyme
VardenafilP-glycoprotein 1transporter
TerbutalineBeta-2 adrenergic receptortarget
TerbutalineCholinesteraseenzyme
TerbutalineBeta-3 adrenergic receptortarget
TerbutalineBeta-1 adrenergic receptortarget
AmantadineDopamine D2 receptortarget
AmantadineMatrix protein 2target
AmantadineAromatic-L-amino-acid decarboxylaseenzyme
AmantadineAmine oxidase [flavin-containing] Benzyme
AmantadineSolute carrier family 22 member 2transporter
AmantadineSolute carrier family 22 member 1transporter
AmantadineGlutamate receptor ionotropic, NMDA 3Atarget
AmantadineNeuronal acetylcholine receptor subunit alpha-7target
AmantadineNeuronal acetylcholine receptor subunit alpha-4target
AmantadineNeuronal acetylcholine receptor subunit alpha-3target
MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
MetronidazoleCytochrome P450 2C9enzyme
MetronidazoleCytochrome P450 3A4enzyme
MetronidazoleCytochrome P450 2C8enzyme
MetronidazoleUDP-glucuronosyltransferase 1-1enzyme
MetronidazoleAnaerobic bacterial DNAtarget
MetronidazoleProtozoal DNAtarget
MetronidazoleP-glycoprotein 1transporter
MetronidazoleCytochrome P450 2A6enzyme
MetronidazoleCytochrome P450 3A5enzyme
MetronidazoleCytochrome P450 3A7enzyme
FamotidineHistamine H2 receptortarget
FamotidineSolute carrier family 22 member 2transporter
FamotidineSolute carrier family 22 member 8transporter
FamotidineMultidrug and toxin extrusion protein 1transporter
FamotidineCytochrome P450 1A2enzyme
FamotidineSolute carrier family 22 member 6transporter
MaprotilineHistamine H1 receptortarget
MaprotilineSodium-dependent noradrenaline transportertarget
MaprotilineAlpha-1 adrenergic receptorstarget
MaprotilineCytochrome P450 2D6enzyme
MaprotilineAlpha-1-acid glycoprotein 1carrier
MaprotilineMuscarinic acetylcholine receptor M1target
MaprotilineMuscarinic acetylcholine receptor M2target
MaprotilineMuscarinic acetylcholine receptor M3target
MaprotilineMuscarinic acetylcholine receptor M4target
MaprotilineMuscarinic acetylcholine receptor M5target
MaprotilineCytochrome P450 1A2enzyme
Maprotiline5-hydroxytryptamine receptor 2Atarget
Maprotiline5-hydroxytryptamine receptor 2Ctarget
Maprotiline5-hydroxytryptamine receptor 7target
MaprotilineDopamine D2 receptortarget
MaprotilineAlpha-2 adrenergic receptorstarget
SalmeterolBeta-2 adrenergic receptortarget
SalmeterolCytochrome P450 3A4enzyme
SalmeterolCytochrome P450 2C8enzyme
SalmeterolCytochrome P450 3A5enzyme
SalmeterolCytochrome P450 3A7enzyme
SalmeterolBeta-1 adrenergic receptortarget
SalmeterolBeta-3 adrenergic receptortarget
SalmeterolSerum albumincarrier
Salmeterolalpha1-acid glycoproteincarrier
SalmeterolSolute carrier family 22 member 1transporter
SalmeterolSolute carrier family 22 member 2transporter
SalmeterolSolute carrier family 22 member 3transporter
FelbamateGlutamate receptor ionotropic, NMDA 2Btarget
FelbamateGlutamate receptor ionotropic, NMDA 2Atarget
FelbamateCytochrome P450 2C19enzyme
FelbamateCytochrome P450 3A4enzyme
FelbamateCytochrome P450 2E1enzyme
FelbamateCytochrome P450 2C9enzyme
FormoterolBeta-2 adrenergic receptortarget
FormoterolBeta-1 adrenergic receptortarget
FormoterolBeta-3 adrenergic receptortarget
FormoterolCytochrome P450 2D6enzyme
FormoterolCytochrome P450 2C19enzyme
FormoterolCytochrome P450 2C9enzyme
FormoterolCytochrome P450 2A6enzyme
FormoterolUDP-glucuronosyltransferase 1A1enzyme
FormoterolUDP-glucuronosyltransferase 1-8enzyme
FormoterolUDP-glucuronosyltransferase 1-9enzyme
FormoterolUDP-glucuronosyltransferase 2B7enzyme
FormoterolUDP-glucuronosyltransferase 2B15enzyme
FormoterolSolute carrier family 22 member 1transporter
FormoterolSolute carrier family 22 member 4transporter
FormoterolSolute carrier family 22 member 5transporter
FormoterolSolute carrier family 22 member 3transporter
FormoterolSerum albumincarrier
SalbutamolBeta-2 adrenergic receptortarget
SalbutamolBeta-1 adrenergic receptortarget
SalbutamolCytochrome P450 3A4enzyme
SalbutamolBeta-3 adrenergic receptortarget
SulfamethoxazoleCytochrome P450 2C9enzyme
SulfamethoxazoleSerum albumincarrier
SulfamethoxazoleArylamine N-acetyltransferase 1enzyme
SulfamethoxazoleArylamine N-acetyltransferase 2enzyme
SulfamethoxazoleDihydropteroate synthasetarget
SulfamethoxazoleCytochrome P450 3A4enzyme
SulfamethoxazoleBile salt export pumptransporter
KetoconazoleCytochrome P450 3A4enzyme
KetoconazoleCytochrome P450 2C9enzyme
KetoconazoleCytochrome P450 2C19enzyme
KetoconazoleCytochrome P450 3A5enzyme
KetoconazoleCytochrome P450 1A2enzyme
KetoconazoleCytochrome P450 2C8enzyme
KetoconazoleCytochrome P450 1A1enzyme
KetoconazoleCytochrome P450 2D6enzyme
KetoconazoleBile salt export pumptransporter
KetoconazoleP-glycoprotein 1transporter
KetoconazoleCytochrome P450 11B1, mitochondrialenzyme
KetoconazoleCytochrome P450 1B1enzyme
KetoconazoleCytochrome P450 2A6enzyme
KetoconazoleCytochrome P450 2B6enzyme
KetoconazoleLanosterol 14-alpha demethylasetarget
KetoconazoleAndrogen receptortarget
KetoconazoleSteroid 17-alpha-hydroxylase/17,20 lyasetarget
KetoconazoleSteroid 21-hydroxylasetarget
KetoconazolePotassium voltage-gated channel subfamily H member 2target
KetoconazoleNuclear receptor subfamily 1 group I member 2target
KetoconazoleNuclear receptor subfamily 1 group I member 3target
KetoconazoleUDP-glucuronosyltransferase 1-1enzyme
KetoconazoleUDP-glucuronosyltransferase 2B7enzyme
KetoconazoleSolute carrier organic anion transporter family member 1B1transporter
KetoconazoleCytochrome P450 4F12enzyme
KetoconazoleLeukotriene-B(4) omega-hydroxylase 1enzyme
KetoconazoleSerum albumincarrier
KetoconazoleSex hormone-binding globulincarrier
KetoconazoleCytochrome P450 19A1enzyme
KetoconazoleUDP-glucuronosyltransferase 1-7enzyme
TolterodineMuscarinic acetylcholine receptor M1target
TolterodineMuscarinic acetylcholine receptor M2target
TolterodineMuscarinic acetylcholine receptor M3target
TolterodineCytochrome P450 2D6enzyme
TolterodineCytochrome P450 3A4enzyme
TolterodineCytochrome P450 2C9enzyme
TolterodineCytochrome P450 2C19enzyme
TolterodineMuscarinic acetylcholine receptor M4target
TolterodineMuscarinic acetylcholine receptor M5target
NorfloxacinDNA gyrase subunit Atarget
NorfloxacinDNA topoisomerase 4 subunit Atarget
NorfloxacinDNA topoisomerase 2-alphatarget
NorfloxacinCytochrome P450 1A2enzyme
NorfloxacinCytochrome P450 3A4enzyme
NorfloxacinSolute carrier family 22 member 5transporter
NorfloxacinSolute carrier family 22 member 6transporter
NorfloxacinCytochrome P450 1A1enzyme
PromethazineDopamine D2 receptortarget
PromethazineHistamine H1 receptortarget
PromethazineMuscarinic acetylcholine receptor M4target
PromethazineMuscarinic acetylcholine receptor M1target
PromethazineMuscarinic acetylcholine receptor M5target
PromethazineMuscarinic acetylcholine receptor M2target
PromethazineMuscarinic acetylcholine receptor M3target
PromethazineCalmodulintarget
PromethazineCytochrome P450 2D6enzyme
PromethazineCytochrome P450 2B6enzyme
PromethazineP-glycoprotein 1transporter
PromethazineCytochrome P450 2C9enzyme
PromethazineHistamine H2 receptortarget
PromethazineAlpha adrenergic receptortarget
PromethazineP2 Purinoceptorstarget
PromethazineVoltage-gated sodium channel alpha subunittarget
PromethazineVoltage-gated Potassium Channelstarget
PromethazineCanalicular multispecific organic anion transporter 2transporter
PromethazineMultidrug resistance-associated protein 4transporter
PromethazineSerum albumincarrier
AtazanavirHuman immunodeficiency virus type 1 proteasetarget
AtazanavirCytochrome P450 3A4enzyme
AtazanavirCytochrome P450 2C9enzyme
AtazanavirP-glycoprotein 1transporter
AtazanavirMultidrug resistance-associated protein 1transporter
AtazanavirSerum albumincarrier
AtazanavirUDP-glucuronosyltransferase 1-1enzyme
AtazanavirSolute carrier organic anion transporter family member 1B1transporter
AtazanavirSolute carrier organic anion transporter family member 1B3transporter
AtazanavirCytochrome P450 2C8enzyme
AtazanavirBile salt export pumptransporter
Atazanaviralpha1-acid glycoproteincarrier
AtazanavirCytochrome P450 1A2enzyme
AtazanavirSolute carrier organic anion transporter family member 2B1transporter
DiphenhydramineHistamine H1 receptortarget
DiphenhydramineCytochrome P450 2D6enzyme
DiphenhydramineCytochrome P450 2C9enzyme
DiphenhydramineCytochrome P450 2C19enzyme
DiphenhydramineSolute carrier family 22 member 2transporter
DiphenhydramineSolute carrier family 22 member 5transporter
DiphenhydramineProstaglandin G/H synthase 1enzyme
DiphenhydramineMuscarinic acetylcholine receptor M2target
DoxepinSodium-dependent serotonin transportertarget
DoxepinSodium-dependent noradrenaline transportertarget
DoxepinHistamine H1 receptortarget
DoxepinHistamine H2 receptortarget
DoxepinCytochrome P450 2D6enzyme
DoxepinMuscarinic acetylcholine receptor M1target
DoxepinMuscarinic acetylcholine receptor M2target
DoxepinMuscarinic acetylcholine receptor M3target
DoxepinMuscarinic acetylcholine receptor M4target
DoxepinMuscarinic acetylcholine receptor M5target
DoxepinAlpha-1A adrenergic receptortarget
Doxepin5-hydroxytryptamine receptor 1Atarget
Doxepin5-hydroxytryptamine receptor 2Atarget
DoxepinCytochrome P450 2C19enzyme
DoxepinCytochrome P450 2C9enzyme
DoxepinCytochrome P450 1A2enzyme
DoxepinP-glycoprotein 1transporter
Doxepin5-hydroxytryptamine receptor 2Btarget
Doxepin5-hydroxytryptamine receptor 2Ctarget
DoxepinAlpha-1B adrenergic receptortarget
DoxepinAlpha-1D adrenergic receptortarget
DoxepinCytochrome P450 3A4enzyme
Doxepin5-hydroxytryptamine receptor 6target
DoxepinHistamine H4 receptortarget
DoxepinPotassium voltage-gated channel subfamily H member 2target
DoxepinSerum albumincarrier
DoxepinAlpha-1-acid glycoprotein 1carrier
DesipramineMuscarinic acetylcholine receptor M1target
DesipramineSodium-dependent noradrenaline transportertarget
DesipramineBeta-2 adrenergic receptortarget
DesipramineMuscarinic acetylcholine receptor M2target
DesipramineSodium-dependent serotonin transportertarget
DesipramineHistamine H1 receptortarget
DesipramineBeta-1 adrenergic receptortarget
DesipramineCytochrome P450 2D6enzyme
DesipramineMuscarinic acetylcholine receptor M3target
DesipramineMuscarinic acetylcholine receptor M4target
DesipramineMuscarinic acetylcholine receptor M5target
DesipramineAlpha-1 adrenergic receptorstarget
Desipramine5-hydroxytryptamine receptor 2Atarget
DesipramineAlpha-1-acid glycoprotein 1carrier
DesipramineCytochrome P450 2B6enzyme
DesipramineCytochrome P450 3A4enzyme
DesipramineSolute carrier family 22 member 2transporter
DesipramineSolute carrier family 22 member 1transporter
DesipramineSolute carrier family 22 member 3transporter
DesipramineSolute carrier family 22 member 5transporter
DesipramineP-glycoprotein 1transporter
DesipramineSolute carrier family 22 member 4transporter
DesipramineCytochrome P450 1A2enzyme
DesipramineCytochrome P450 2E1enzyme
DesipramineSphingomyelin phosphodiesterasetarget
Desipramine5-hydroxytryptamine receptor 1Atarget
Desipramine5-hydroxytryptamine receptor 2Ctarget
DesipramineDopamine D2 receptortarget
DesipramineAlpha-2 adrenergic receptorstarget
ItraconazoleLanosterol 14-alpha demethylasetarget
ItraconazoleLanosterol 14-alpha demethylasetarget
ItraconazoleCytochrome P450 3A4enzyme
ItraconazoleCytochrome P450 3A5enzyme
ItraconazoleCytochrome P450 3A7enzyme
ItraconazoleCytochrome P450 2B6enzyme
ItraconazoleP-glycoprotein 1transporter
ItraconazoleCytochrome P450 1A1enzyme
ItraconazoleCytochrome P450 2E1enzyme
ItraconazoleSolute carrier organic anion transporter family member 2B1transporter
DesfluraneNADH-ubiquinone oxidoreductase chain 1target
DesfluraneGlycine receptor subunit alpha-1target
DesfluraneGlutamate receptor 1target
DesfluraneGABA(A) Receptortarget
DesfluranePotassium voltage-gated channel subfamily A member 1target
DesfluraneATP synthase subunit delta, mitochondrialtarget
DesfluraneSerum albumincarrier
DesfluraneCalcium transporting ATPasestarget
MetoclopramideMuscarinic acetylcholine receptor M1target
MetoclopramideDopamine D2 receptortarget
MetoclopramideCytochrome P450 2D6enzyme
Metoclopramide5-hydroxytryptamine receptor 4target
Metoclopramide5-hydroxytryptamine receptor 3Atarget
MetoclopramideCytochrome P450 3A4enzyme
MetoclopramideCytochrome P450 1A2enzyme
MetoclopramideP-glycoprotein 1transporter
MetoclopramideAlpha-1-acid glycoprotein 1carrier
SevofluraneCalcium-transporting ATPase type 2C member 1target
SevofluraneNADH-ubiquinone oxidoreductase chain 1target
SevofluraneGlycine receptor subunit alpha-1target
SevofluraneGlutamate receptor 1target
SevofluraneGamma-aminobutyric acid receptor subunit alpha-1target
SevofluraneCytochrome P450 2E1enzyme
SevofluraneSerum albumincarrier
SevofluraneCytochrome P450 2A6enzyme
SevofluraneCytochrome P450 2B6enzyme
SevofluraneCytochrome P450 3A4enzyme
SevofluraneGABA(A) Receptortarget
SevofluraneMitochondrial potassium channeltarget
AripiprazoleDopamine D2 receptortarget
Aripiprazole5-hydroxytryptamine receptor 1Atarget
Aripiprazole5-hydroxytryptamine receptor 2Atarget
AripiprazoleCytochrome P450 3A4enzyme
AripiprazoleCytochrome P450 2D6enzyme
Aripiprazole5-hydroxytryptamine receptor 1Btarget
Aripiprazole5-hydroxytryptamine receptor 1Dtarget
Aripiprazole5-hydroxytryptamine receptor 1Etarget
AripiprazoleDopamine D1 receptortarget
AripiprazoleDopamine D5 receptortarget
AripiprazoleDopamine D3 receptortarget
AripiprazoleDopamine D4 receptortarget
Aripiprazole5-hydroxytryptamine receptor 2Ctarget
Aripiprazole5-hydroxytryptamine receptor 3Atarget
Aripiprazole5-hydroxytryptamine receptor 6target
Aripiprazole5-hydroxytryptamine receptor 7target
AripiprazoleHistamine H1 receptortarget
AripiprazoleAlpha-1A adrenergic receptortarget
AripiprazoleAlpha-1B adrenergic receptortarget
AripiprazoleAlpha-2A adrenergic receptortarget
AripiprazoleAlpha-2B adrenergic receptortarget
AripiprazoleAlpha-2C adrenergic receptortarget
AripiprazoleCytochrome P450 3A5enzyme
AripiprazoleCytochrome P450 3A7enzyme
AripiprazoleSerum albumincarrier
Aripiprazole5-hydroxytryptamine receptor 2Btarget
Aripiprazole5-hydroxytryptamine receptor 5Atarget
AripiprazoleBeta-1 adrenergic receptortarget
AripiprazoleBeta-2 adrenergic receptortarget
AripiprazoleHistamine H2 receptortarget
AripiprazoleHistamine H3 receptortarget
AripiprazoleHistamine H4 receptortarget
AripiprazoleMuscarinic acetylcholine receptor M1target
AripiprazoleMuscarinic acetylcholine receptor M2target
AripiprazoleMuscarinic acetylcholine receptor M3target
AripiprazoleMuscarinic acetylcholine receptor M4target
AripiprazoleMuscarinic acetylcholine receptor M5target
AripiprazoleKappa-type opioid receptortarget
AripiprazoleMu-type opioid receptortarget
AripiprazoleDelta-type opioid receptortarget
AripiprazoleGlutamate (NMDA) receptortarget
AripiprazoleSodium-dependent dopamine transportertarget
AripiprazoleSodium-dependent serotonin transportertarget
DasatinibTyrosine-protein kinase ABL1target
DasatinibAbelson tyrosine-protein kinase 2target
DasatinibProto-oncogene tyrosine-protein kinase Srctarget
DasatinibTyrosine-protein kinase Fyntarget
DasatinibTyrosine-protein kinase Lcktarget
DasatinibTyrosine-protein kinase Yestarget
DasatinibMast/stem cell growth factor receptor Kittarget
DasatinibPlatelet-derived growth factor receptor betatarget
DasatinibEphrin type-A receptor 2target
DasatinibSignal transducer and activator of transcription 5Btarget
DasatinibCytochrome P450 3A4enzyme
DasatinibP-glycoprotein 1transporter
DasatinibATP-binding cassette sub-family G member 2transporter
DasatinibCytochrome P450 1A1enzyme
DasatinibCytochrome P450 1A2enzyme
DasatinibCytochrome P450 1B1enzyme
DasatinibCytochrome P450 3A5enzyme
DasatinibDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DasatinibTyrosine-protein kinase BTKtarget
DasatinibNuclear receptor subfamily 4 group A member 3target
DasatinibBreakpoint cluster region proteintarget
DasatinibTyrosine-protein kinase CSKtarget
DasatinibEphrin type-A receptor 5target
DasatinibEphrin type-B receptor 4target
DasatinibTyrosine-protein kinase Fgrtarget
DasatinibTyrosine-protein kinase FRKtarget
DasatinibHeat shock cognate 71 kDa proteintarget
DasatinibTyrosine-protein kinase Lyntarget
DasatinibMitogen-activated protein kinase kinase kinase MLTtarget
DasatinibMitogen-activated protein kinase 14target
DasatinibAmidophosphoribosyltransferasetarget
LapatinibEpidermal growth factor receptortarget
LapatinibReceptor tyrosine-protein kinase erbB-2target
LapatinibCytochrome P450 3A4enzyme
LapatinibCytochrome P450 2C8enzyme
LapatinibP-glycoprotein 1transporter
LapatinibAntigen peptide transporter 1transporter
LapatinibCytochrome P450 3A5enzyme
LapatinibCytochrome P450 2C19enzyme
PosaconazoleCytochrome P450 3A4enzyme
PosaconazoleP-glycoprotein 1transporter
PosaconazoleCytochrome P450 51target
SunitinibPlatelet-derived growth factor receptor betatarget
SunitinibVascular endothelial growth factor receptor 1target
SunitinibVascular endothelial growth factor receptor 2target
SunitinibVascular endothelial growth factor receptor 3target
SunitinibMast/stem cell growth factor receptor Kittarget
SunitinibReceptor-type tyrosine-protein kinase FLT3target
SunitinibMacrophage colony-stimulating factor 1 receptortarget
SunitinibPlatelet-derived growth factor receptor alphatarget
SunitinibCytochrome P450 3A4enzyme
SunitinibCytochrome P450 3A5enzyme
SunitinibCytochrome P450 3A7enzyme
SunitinibMultidrug resistance-associated protein 4transporter
SunitinibP-glycoprotein 1transporter
SunitinibCanalicular multispecific organic anion transporter 1transporter
SunitinibATP-binding cassette sub-family G member 2transporter
ArformoterolBeta-2 adrenergic receptortarget
ArformoterolCytochrome P450 2D6enzyme
ArformoterolCytochrome P450 2C19enzyme
ArformoterolCytochrome P450 2A6enzyme
ArformoterolCytochrome P450 2C9enzyme
MethotrimeprazineDopamine D3 receptortarget
MethotrimeprazineHistamine H1 receptortarget
MethotrimeprazineMuscarinic acetylcholine receptor M1target
MethotrimeprazineMuscarinic acetylcholine receptor M2target
MethotrimeprazineMuscarinic acetylcholine receptor M3target
MethotrimeprazineMuscarinic acetylcholine receptor M4target
MethotrimeprazineMuscarinic acetylcholine receptor M5target
MethotrimeprazineAlpha-1A adrenergic receptortarget
MethotrimeprazineAlpha-1B adrenergic receptortarget
MethotrimeprazineAlpha-1D adrenergic receptortarget
MethotrimeprazineCytochrome P450 2D6enzyme
MethotrimeprazineDopamine D2 receptortarget
MethotrimeprazineDopamine D1 receptortarget
MethotrimeprazineDopamine D5 receptortarget
MethotrimeprazineDopamine D4 receptortarget
MethotrimeprazineAlpha-2A adrenergic receptortarget
MethotrimeprazineAlpha-2B adrenergic receptortarget
MethotrimeprazineAlpha-2C adrenergic receptortarget
Methotrimeprazine5-hydroxytryptamine receptor 2Atarget
Methotrimeprazine5-hydroxytryptamine receptor 2Ctarget
MethotrimeprazineCytochrome P450 2E1enzyme
SolifenacinMuscarinic acetylcholine receptor M3target
SolifenacinMuscarinic acetylcholine receptor M1target
SolifenacinCytochrome P450 3A4enzyme
SolifenacinMuscarinic acetylcholine receptor M2target
SolifenacinMuscarinic acetylcholine receptor M4target
SolifenacinMuscarinic acetylcholine receptor M5target
Solifenacinalpha1-acid glycoproteincarrier
SolifenacinCytochrome P450 1A1enzyme
SolifenacinCytochrome P450 2D6enzyme
ThiothixeneCytochrome P450 1A2enzyme
ThiothixeneCytochrome P450 2D6enzyme
ThiothixeneDopamine D2 receptortarget
ThiothixeneDopamine D1 receptortarget
Thiothixene5-hydroxytryptamine receptor 2Atarget
ThiothixeneSolute carrier family 22 member 1transporter
ThiothixeneSerum albumincarrier
VorinostatHistone deacetylase 1target
VorinostatHistone deacetylase 2target
VorinostatHistone deacetylase 3target
VorinostatHistone deacetylase 6target
VorinostatHistone deacetylase 8target
VorinostatAcetoin utilization proteintarget
EzogabinePotassium voltage-gated channel subfamily KQT member 2target
EzogabinePotassium voltage-gated channel subfamily KQT member 3target
EzogabinePotassium voltage-gated channel subfamily KQT member 4target
EzogabinePotassium voltage-gated channel subfamily KQT member 5target
EzogabineUDP-glucuronosyltransferase 1-1enzyme
EzogabineUDP-glucuronosyltransferase 1-3enzyme
EzogabineUDP-glucuronosyltransferase 1-4enzyme
EzogabineUDP-glucuronosyltransferase 1-9enzyme
EzogabineArylamine N-acetyltransferase 2enzyme
IndacaterolBeta-2 adrenergic receptortarget
IndacaterolCytochrome P450 3A4enzyme
IndacaterolUDP-glucuronosyltransferase 1-1enzyme
IndacaterolP-glycoprotein 1transporter
PasireotideSomatostatin receptor type 1target
PasireotideSomatostatin receptor type 2target
PasireotideSomatostatin receptor type 3target
PasireotideSomatostatin receptor type 5target
PasireotideCytochrome P450 3A4enzyme
DegarelixGonadotropin-releasing hormone receptortarget
BuserelinLutropin-choriogonadotropic hormone receptortarget
BuserelinGonadotropin-releasing hormone receptortarget
BuserelinCytochrome P450 19A1enzyme
HistrelinGonadotropin-releasing hormone receptortarget
TriptorelinGonadotropin-releasing hormone receptortarget
RilpivirineCytochrome P450 3A4enzyme
RilpivirineReverse transcriptase/RNaseHtarget
RilpivirineNuclear receptor subfamily 1 group I member 2target
RilpivirineCytochrome P450 2C19enzyme
RilpivirineCytochrome P450 2B6enzyme
RilpivirineP-glycoprotein 1transporter
RilpivirineATP-binding cassette sub-family G member 2transporter
RilpivirineSolute carrier organic anion transporter family member 1B1transporter
RilpivirineSolute carrier organic anion transporter family member 1B3transporter
RilpivirineSerum albumincarrier
RilpivirineCytochrome P450 2D6enzyme
EribulinApoptosis regulator Bcl-2target
EribulinTubulin beta-1 chaintarget
MirabegronCytochrome P450 3A4enzyme
MirabegronCytochrome P450 2D6enzyme
MirabegronP-glycoprotein 1transporter
MirabegronSolute carrier organic anion transporter family member 1A2transporter
MirabegronSerum albumincarrier
MirabegronAlpha-1-acid glycoprotein 1carrier
MirabegronCholinesteraseenzyme
MirabegronBeta-3 adrenergic receptortarget
DabrafenibCytochrome P450 3A4enzyme
DabrafenibCytochrome P450 2C8enzyme
DabrafenibP-glycoprotein 1transporter
DabrafenibATP-binding cassette sub-family G member 2transporter
DabrafenibSolute carrier organic anion transporter family member 1B1transporter
DabrafenibSolute carrier organic anion transporter family member 1B3transporter
DabrafenibSolute carrier family 22 member 6transporter
DabrafenibSolute carrier family 22 member 8transporter
DabrafenibSerine/threonine-protein kinase B-raftarget
DabrafenibRAF proto-oncogene serine/threonine-protein kinasetarget
DabrafenibSerine/threonine-protein kinase SIK1target
DabrafenibSerine/threonine-protein kinase Nek11target
DabrafenibLIM domain kinase 1target
DabrafenibCytochrome P450 2B6enzyme
DabrafenibCytochrome P450 2C9enzyme
OlodaterolBeta-2 adrenergic receptortarget
OlodaterolCytochrome P450 2C9enzyme
OlodaterolCytochrome P450 2C8enzyme
VilanterolCytochrome P450 3A4enzyme
VilanterolBeta-2 adrenergic receptortarget
MequitazineHistamine H1 receptortarget
MequitazineCytochrome P450 2D6enzyme
MequitazineCytochrome P450 3A4enzyme
AmodiaquineHistamine N-methyltransferasetarget
AmodiaquineCytochrome P450 2C8enzyme
AmodiaquineCytochrome P450 2D6enzyme
AmodiaquineFe(II)-protoporphyrin IXtarget
AmodiaquineCytochrome P450 1A1enzyme
AmodiaquineCytochrome P450 1B1enzyme
AmodiaquineCytochrome P450 2C9enzyme
AmodiaquineP-glycoprotein 1transporter
TandutinibReceptor-type tyrosine-protein kinase FLT3target
TandutinibPlatelet-derived growth factor Dtarget
DifloxacinCytochrome P450 1A2enzyme
DifloxacinCytochrome P450 1A1enzyme
EnoxacinDNA gyrase subunit Atarget
EnoxacinDNA topoisomerase 4 subunit Atarget
EnoxacinDNA topoisomerase 2-alphatarget
EnoxacinCytochrome P450 1A2enzyme
FleroxacinDNA topoisomerase 2-alphatarget
FleroxacinDNA gyrase subunit Atarget
FleroxacinDNA topoisomerase 4 subunit Atarget
FlumequineCytochrome P450 1A2enzyme
OrbifloxacinCytochrome P450 1A2enzyme
Oxolinic acidCytochrome P450 1A2enzyme
PazufloxacinCytochrome P450 1A2enzyme
PefloxacinDNA gyrase subunit Atarget
PefloxacinDNA topoisomerase 4 subunit Atarget
PefloxacinDNA topoisomerase 2-alphatarget
PefloxacinCytochrome P450 1A2enzyme
PefloxacinDNA topoisomerase 1target
Pipemidic acidCytochrome P450 1A2enzyme
PrulifloxacinCytochrome P450 1A2enzyme
RosoxacinDNA topoisomerase 4 subunit Atarget
RosoxacinDNA gyrase subunit Btarget
RosoxacinCytochrome P450 1A2enzyme
RufloxacinCytochrome P450 1A2enzyme
SarafloxacinCytochrome P450 1A2enzyme
CilostazolcGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
CilostazolCytochrome P450 2C19enzyme
CilostazolCytochrome P450 3A4enzyme
CilostazolCytochrome P450 3A5enzyme
CilostazolCytochrome P450 3A7enzyme
CilostazolCytochrome P450 1A2enzyme
CilostazolCytochrome P450 2D6enzyme
GatifloxacinSerum albumincarrier
GatifloxacinDNA gyrase subunit Atarget
GatifloxacinDNA gyrase subunit Btarget
GatifloxacinDNA topoisomerase 4 subunit Atarget
GatifloxacinDNA topoisomerase 4 subunit Btarget
GatifloxacinCytochrome P450 1A2enzyme
HydroxychloroquineDNAtarget
HydroxychloroquineToll-like receptor 7target
HydroxychloroquineToll-like receptor 9target
HydroxychloroquineCytochrome P450 2D6enzyme
HydroxychloroquineP-glycoprotein 1transporter
HydroxychloroquineSerum albumincarrier
Hydroxychloroquinealpha1-acid glycoproteincarrier
HydroxychloroquineCytochrome P450 3A4enzyme
HydroxychloroquineSolute carrier organic anion transporter family member 1A2transporter
HydroxychloroquineAngiotensin-converting enzyme 2target
HydroxychloroquineCytochrome P450 2C8enzyme
AcrivastineHistamine H1 receptortarget
AlcaftadineHistamine H1 receptortarget
AlimemazineHistamine H1 receptortarget
Aripiprazole lauroxilDopamine D2 receptortarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 1Atarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 2Atarget
Aripiprazole lauroxilCytochrome P450 3A4enzyme
Aripiprazole lauroxilCytochrome P450 2D6enzyme
Aripiprazole lauroxil5-hydroxytryptamine receptor 1Btarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 1Dtarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 1Etarget
Aripiprazole lauroxilDopamine D1 receptortarget
Aripiprazole lauroxilDopamine D5 receptortarget
Aripiprazole lauroxilDopamine D3 receptortarget
Aripiprazole lauroxilDopamine D4 receptortarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 2Ctarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 3Atarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 6target
Aripiprazole lauroxil5-hydroxytryptamine receptor 7target
Aripiprazole lauroxilHistamine H1 receptortarget
Aripiprazole lauroxilAlpha-1A adrenergic receptortarget
Aripiprazole lauroxilAlpha-1B adrenergic receptortarget
Aripiprazole lauroxilAlpha-2A adrenergic receptortarget
Aripiprazole lauroxilAlpha-2B adrenergic receptortarget
Aripiprazole lauroxilAlpha-2C adrenergic receptortarget
Aripiprazole lauroxilMuscarinic acetylcholine receptor M1target
Aripiprazole lauroxilMuscarinic acetylcholine receptor M2target
Aripiprazole lauroxilMuscarinic acetylcholine receptor M3target
Aripiprazole lauroxilMuscarinic acetylcholine receptor M4target
Aripiprazole lauroxilMuscarinic acetylcholine receptor M5target
Aripiprazole lauroxilCytochrome P450 3A5enzyme
Aripiprazole lauroxilCytochrome P450 3A7enzyme
Aripiprazole lauroxilSerum albumincarrier
AzatadineHistamine H1 receptortarget
AzatadineCytochrome P450 3A4enzyme
BenzatropineMuscarinic acetylcholine receptor M1target
BenzatropineSodium-dependent dopamine transportertarget
BenzatropineHistamine H1 receptortarget
BenzatropineSerum albumincarrier
BenzatropineSodium-dependent serotonin transportertarget
BenzatropineSodium-dependent noradrenaline transportertarget
BilastineHistamine H1 receptortarget
BilastineATP-binding cassette sub-family B member 5transporter
BilastineSolute carrier organic anion transporter family member 1A2transporter
BilastineSolute carrier organic anion transporter family member 2B1transporter
BuclizineHistamine H1 receptortarget
BuclizineMuscarinic acetylcholine receptor M1target
CetirizineHistamine H1 receptortarget
CetirizineP-glycoprotein 1transporter
ChlorcyclizineHistamine H1 receptortarget
ChlorprothixeneDopamine D1 receptortarget
ChlorprothixeneDopamine D2 receptortarget
ChlorprothixeneDopamine D3 receptortarget
Chlorprothixene5-hydroxytryptamine receptor 2Atarget
ChlorprothixeneHistamine H1 receptortarget
ChlorprothixeneMuscarinic acetylcholine receptor M1target
ChlorprothixeneMuscarinic acetylcholine receptor M2target
ChlorprothixeneMuscarinic acetylcholine receptor M3target
ChlorprothixeneMuscarinic acetylcholine receptor M4target
ChlorprothixeneMuscarinic acetylcholine receptor M5target
ChlorprothixeneP-glycoprotein 1transporter
ChlorprothixeneSerotonin Receptorstarget
CyclizineHistamine H1 receptortarget
CyclizineEstrogen sulfotransferasetarget
CyclizineCytochrome P450 2C9enzyme
Cyproheptadine5-hydroxytryptamine receptor 2Atarget
CyproheptadineHistamine H1 receptortarget
CyproheptadineMuscarinic acetylcholine receptor M1target
CyproheptadineMuscarinic acetylcholine receptor M2target
CyproheptadineMuscarinic acetylcholine receptor M3target
Cyproheptadine5-hydroxytryptamine receptor 2Ctarget
CyproheptadineUDP-glucuronosyltransferase 1-3enzyme
Cyproheptadine5-hydroxytryptamine receptor 7target
DexbrompheniramineHistamine H1 receptortarget
Dosulepin5-hydroxytryptamine receptor 1Atarget
Dosulepin5-hydroxytryptamine receptor 2Atarget
DosulepinCytochrome P450 2D6enzyme
DosulepinCytochrome P450 1A2enzyme
DosulepinCytochrome P450 2C19enzyme
DosulepinCytochrome P450 2C9enzyme
DosulepinHistamine H1 receptortarget
DosulepinMuscarinic acetylcholine receptor M1target
DosulepinMuscarinic acetylcholine receptor M2target
DosulepinMuscarinic acetylcholine receptor M3target
DosulepinMuscarinic acetylcholine receptor M4target
DosulepinMuscarinic acetylcholine receptor M5target
DosulepinSodium-dependent noradrenaline transportertarget
DosulepinSodium-dependent serotonin transportertarget
DosulepinAlpha-1 adrenergic receptorstarget
DosulepinAlpha-2 adrenergic receptorstarget
DoxylamineHistamine H1 receptortarget
DoxylamineMuscarinic acetylcholine receptortarget
DoxylamineCYP2B proteinenzyme
DoxylamineNuclear receptor subfamily 1 group I member 3target
EbastineCytochrome P450 3A4enzyme
EpinastineHistamine H1 receptortarget
EpinastineHistamine H2 receptortarget
EpinastineAlpha-1A adrenergic receptortarget
EpinastineAlpha-2A adrenergic receptortarget
Epinastine5-hydroxytryptamine receptor 2Atarget
Epinastine5-hydroxytryptamine receptor 7target
EpinastineP-glycoprotein 1transporter
EpinastineCytochrome P450 2B6enzyme
EpinastineCytochrome P450 2D6enzyme
EpinastineCytochrome P450 3A4enzyme
KetotifenHistamine H1 receptortarget
Ketotifen6-phosphogluconate dehydrogenase, decarboxylatingtarget
LevocabastineNeurotensin receptor type 2target
LevocabastineHistamine H1 receptortarget
LevocetirizineHistamine H1 receptortarget
LevocetirizineSolute carrier family 22 member 11transporter
LevocetirizineCytochrome P450 3A4enzyme
LevocetirizineSerum albumincarrier
MepyramineCytochrome P450 2D6enzyme
MepyramineHistamine H1 receptortarget
MepyramineSolute carrier family 22 member 4transporter
MepyramineSolute carrier family 22 member 5transporter
OrphenadrineGlutamate receptor ionotropic, NMDA 1target
OrphenadrineGlutamate receptor ionotropic, NMDA 2Dtarget
OrphenadrineGlutamate receptor ionotropic, NMDA 3Btarget
OrphenadrineGlutamate receptor ionotropic, NMDA 3Atarget
OrphenadrineHistamine H1 receptortarget
OrphenadrineCytochrome P450 2B6enzyme
OrphenadrineCytochrome P450 2E1enzyme
OrphenadrineCytochrome P450 3A4enzyme
OrphenadrineSodium-dependent noradrenaline transportertarget
OrphenadrineSodium channel protein type 10 subunit alphatarget
OrphenadrineCytochrome P450 1A2enzyme
OrphenadrineCytochrome P450 2D6enzyme
PheniramineHistamine H1 receptortarget
PheniramineNuclear receptor subfamily 1 group I member 3target
PheniramineHistamine H4 receptortarget
RupatadineCytochrome P450 3A4enzyme
RupatadineCytochrome P450 2C9enzyme
RupatadineCytochrome P450 2C19enzyme
RupatadineCytochrome P450 2D6enzyme
RupatadinePlatelet-activating factor receptortarget
RupatadineHistamine H1 receptortarget
TriprolidineHistamine H1 receptortarget
BrompheniramineHistamine H1 receptortarget
BrompheniramineMuscarinic acetylcholine receptor M1target
BrompheniramineMuscarinic acetylcholine receptor M2target
BrompheniramineMuscarinic acetylcholine receptor M3target
BrompheniramineMuscarinic acetylcholine receptor M4target
BrompheniramineMuscarinic acetylcholine receptor M5target
AjmalineAlpha-1-acid glycoprotein 1carrier
AjmalineSodium channel protein type 5 subunit alphatarget
AnisodamineCytochrome P450 2D6enzyme
AranidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
AranidipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
AranidipineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
AranidipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
AranidipineAlpha adrenergic receptortarget
AranidipineSerum albumincarrier
AranidipineAlpha-1-acid glycoprotein 1carrier
AranidipineCytochrome P450 3A4enzyme
BencyclaneCytochrome P450 3A4enzyme
BretyliumSodium/potassium-transporting ATPase subunit alpha-1target
BupranololBeta-1 adrenergic receptortarget
BupranololBeta-2 adrenergic receptortarget
BupranololBeta-3 adrenergic receptortarget
BupranololCytochrome P450 2D6enzyme
CariporideSodium/hydrogen exchanger 1target
CariporideMyeloperoxidaseenzyme
CarteololBeta-2 adrenergic receptortarget
CarteololBeta-1 adrenergic receptortarget
CarteololCytochrome P450 2D6enzyme
CeliprololBeta-1 adrenergic receptortarget
CeliprololBeta-2 adrenergic receptortarget
CeliprololBeta-3 adrenergic receptortarget
CeliprololAlpha-2A adrenergic receptortarget
CeliprololAlpha-2B adrenergic receptortarget
CeliprololAlpha-2C adrenergic receptortarget
CeliprololCytochrome P450 2D6enzyme
DigoxinSodium/potassium-transporting ATPase subunit alpha-1target
DigoxinCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DigoxinP-glycoprotein 1transporter
DigoxinSolute carrier organic anion transporter family member 4C1transporter
DigoxinBile salt export pumptransporter
DigoxinSolute carrier organic anion transporter family member 1A2transporter
DigoxinOrganic solute transporter subunit alphatransporter
DigoxinOrganic solute transporter subunit betatransporter
DigoxinSolute carrier organic anion transporter family member 1B1transporter
DigitoxinSodium/potassium-transporting ATPase subunit alpha-1target
DigitoxinSerum albumincarrier
DigitoxinCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DigitoxinCytochrome P450 3A4enzyme
DigitoxinSolute carrier organic anion transporter family member 1A2transporter
DigitoxinSolute carrier organic anion transporter family member 4C1transporter
DigitoxinP-glycoprotein 1transporter
EfonidipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
EfonidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
EfonidipineCytochrome P450 3A4enzyme
EncainideSodium channel protein type 5 subunit alphatarget
EncainideCytochrome P450 2D6enzyme
EsmololBeta-1 adrenergic receptortarget
EsmololCytochrome P450 2D6enzyme
EthosuximideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
EthosuximideCytochrome P450 3A4enzyme
EthosuximideCytochrome P450 2E1enzyme
EthosuximideCytochrome P450 3A Subfamilyenzyme
FelodipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
FelodipineCalmodulintarget
FelodipineCytochrome P450 3A4enzyme
FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
FelodipineVoltage-dependent L-type calcium channel subunit beta-2target
FelodipineCytochrome P450 2C8enzyme
FelodipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
FelodipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
FelodipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
FelodipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
FelodipineTroponin C, skeletal muscletarget
FelodipineTroponin C, slow skeletal and cardiac musclestarget
FelodipineMineralocorticoid receptortarget
FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
FelodipineCytochrome P450 3A5enzyme
FelodipineCytochrome P450 3A7enzyme
FelodipineP-glycoprotein 1transporter
FelodipineCytochrome P450 2C9enzyme
FelodipineCytochrome P450 2D6enzyme
FelodipineBile salt export pumptransporter
GallopamilCytochrome P450 3A4enzyme
GallopamilP-glycoprotein 1transporter
HyoscyamineMuscarinic acetylcholine receptor M1target
HyoscyamineMuscarinic acetylcholine receptor M2target
HyoscyamineMuscarinic acetylcholine receptor M3target
HyoscyamineMuscarinic acetylcholine receptor M4target
IndenololCytochrome P450 2D6enzyme
LacidipineCytochrome P450 3A4enzyme
LacidipineSerum albumincarrier
LacidipineAlpha-1-acid glycoprotein 1carrier
LacidipineVoltage-dependent L-type calcium channeltarget
LamotrigineVoltage-gated sodium channel alpha subunittarget
LamotrigineUDP-glucuronosyltransferases (UGTs)enzyme
LamotrigineP-glycoprotein 1transporter
LamotrigineDihydrofolate reductaseenzyme
Lamotrigine5-hydroxytryptamine receptor 3Atarget
LamotrigineVoltage-dependent R-type calcium channel subunit alpha-1E (CACNA1E)target
LamotrigineAdenosine receptor A1target
LamotrigineAdenosine receptor A2atarget
LamotrigineAlpha-1A adrenergic receptortarget
LamotrigineAlpha-2A adrenergic receptortarget
LamotrigineBeta-1 adrenergic receptortarget
LamotrigineD(1) dopamine receptortarget
LamotrigineDopamine D2 receptortarget
LamotrigineGABA(A) Receptortarget
LamotrigineGABA(A) Receptor Benzodiazepine Binding Sitetarget
LamotrigineHistamine H1 receptortarget
LamotrigineKappa-type opioid receptortarget
LamotrigineAcetylcholine receptor subunit alphatarget
Lamotrigine5-hydroxytryptamine receptor 2Atarget
LamotrigineSolute carrier family 22 member 2transporter
LamotrigineSerum albumincarrier
LamotrigineSolute carrier family 22 member 1transporter
LamotrigineGlutamate receptor 1target
LidoflazineCytochrome P450 3A4enzyme
LosartanType-1 angiotensin II receptortarget
LosartanCytochrome P450 3A4enzyme
LosartanCytochrome P450 2C9enzyme
LosartanP-glycoprotein 1transporter
LosartanSolute carrier family 22 member 6transporter
LosartanUDP-glucuronosyltransferase 1-1enzyme
LosartanUDP-glucuronosyltransferase 1-3enzyme
LosartanUDP-glucuronosyltransferase 1-10enzyme
LosartanUDP-glucuronosyltransferase 2B7enzyme
LosartanUDP-glucuronosyltransferase 2B17enzyme
LosartanCytochrome P450 2C19enzyme
LosartanSerum albumincarrier
LosartanSolute carrier family 22 member 12transporter
LosartanSolute carrier family 2, facilitated glucose transporter member 9transporter
LosartanBile salt export pumptransporter
LosartanCytochrome P450 2C8enzyme
LevomentholTransient receptor potential cation channel subfamily A member 1target
LevomentholTransient receptor potential cation channel subfamily M member 8target
LevomentholTransient receptor potential cation channel subfamily V member 3target
LevomentholKappa-type opioid receptortarget
LevomentholVoltage-dependent L-type calcium channeltarget
LevomentholCytochrome P450 3A4enzyme
MethsuximideCytochrome P450 2C19enzyme
MethsuximideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
MoricizineSodium channel protein type 5 subunit alphatarget
NiguldipineAlpha-1A adrenergic receptortarget
NiguldipineCytochrome P450 3A4enzyme
NiguldipineP-glycoprotein 1transporter
NitrendipineCytochrome P450 3A4enzyme
NitrendipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
NitrendipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NitrendipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
NitrendipineVoltage-dependent L-type calcium channel subunit beta-2target
NitrendipineCytochrome P450 3A5enzyme
NitrendipineCytochrome P450 3A7enzyme
NitrendipineP-glycoprotein 1transporter
NitrendipineBile salt export pumptransporter
PerhexilineCarnitine O-palmitoyltransferase 1, liver isoformtarget
PerhexilineCarnitine O-palmitoyltransferase 2, mitochondrialtarget
PerhexilineCytochrome P450 2D6enzyme
PerhexilineCytochrome P450 2B6enzyme
PerhexilineCytochrome P450 3A4enzyme
PerhexilinePotassium voltage-gated channel subfamily H member 2target
PilsicainideBile salt export pumptransporter
PinaveriumVoltage-dependent L-type calcium channel subunit alpha-1Starget
PinaveriumCytochrome P450 3A4enzyme
PregabalinExcitatory amino acid transporter 3transporter
PregabalinVoltage-dependent calcium channel subunit alpha-2/delta-1target
PregabalinLarge neutral amino acids transporter small subunit 1transporter
TalinololCytochrome P450 2D6enzyme
TalinololP-glycoprotein 1transporter
TalinololCanalicular multispecific organic anion transporter 1transporter
TetrahydropalmatineDopamine D1 receptortarget
TetrahydropalmatineDopamine D2 receptortarget
TetrahydropalmatineCytochrome P450 3A4enzyme
TimololBeta-1 adrenergic receptortarget
TimololBeta-2 adrenergic receptortarget
TimololCytochrome P450 2D6enzyme
TimololP-glycoprotein 1transporter
TimololCytochrome P450 2C19enzyme
TimololLysozymetarget
TrimebutineMu-type opioid receptortarget
TrimebutineVoltage-dependent L-type calcium channeltarget
TrimebutineCalcium-activated potassium channeltarget
TrimebutineVoltage-dependent T-type calcium channeltarget
TrimebutineMuscarinic acetylcholine receptor M1target
TrimebutineMuscarinic acetylcholine receptor M2target
TrimebutineMuscarinic acetylcholine receptor M3target
TrimebutineMuscarinic acetylcholine receptor M4target
TrimebutineCytochrome P450 3A4enzyme
TrimethadioneVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
TrimethadioneCytochrome P450 2C19enzyme
TrimethadioneCytochrome P450 2C8enzyme
TrimethadioneCytochrome P450 2C9enzyme
TrimethadioneCytochrome P450 2E1enzyme
TrimethadioneCytochrome P450 3A4enzyme
VernakalantCytochrome P450 2D6enzyme
VernakalantSodium channel protein type 5 subunit alphatarget
VernakalantPotassium voltage-gated channel subfamily A member 5target
VernakalantPotassium voltage-gated channel subfamily D member 3target
VernakalantPotassium voltage-gated channel subfamily H member 2target
ZonisamideSodium channel protein type 1 subunit alphatarget
ZonisamideCarbonic anhydrase 1target
ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
ZonisamideCytochrome P450 3A4enzyme
ZonisamideAldehyde oxidaseenzyme
ZonisamideAmine oxidase [flavin-containing] Btarget
ZonisamideCarbonic anhydrase 2target
ZonisamideCarbonic anhydrase 3target
ZonisamideCarbonic anhydrase 4target
ZonisamideCarbonic anhydrase 5A, mitochondrialtarget
ZonisamideCarbonic anhydrase 5B, mitochondrialtarget
ZonisamideCarbonic anhydrase 6target
ZonisamideCarbonic anhydrase 7target
ZonisamideCarbonic anhydrase-related proteintarget
ZonisamideCarbonic anhydrase 9target
ZonisamideCarbonic anhydrase-related protein 10target
ZonisamideCarbonic anhydrase-related protein 11target
ZonisamideCarbonic anhydrase 12target
ZonisamideCarbonic anhydrase 13target
ZonisamideCarbonic anhydrase 14target
ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Htarget
ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Itarget
ZonisamideSodium channel protein type 2 subunit alphatarget
ZonisamideSodium channel protein type 3 subunit alphatarget
ZonisamideSodium channel protein type 4 subunit alphatarget
ZonisamideSodium channel protein type 5 subunit alphatarget
ZonisamideSodium channel protein type 9 subunit alphatarget
ZonisamideSodium channel protein type 11 subunit alphatarget
ZonisamideSodium channel subunit beta-1target
ZonisamideSodium channel subunit beta-2target
ZonisamideSodium channel subunit beta-3target
ZonisamideSodium channel subunit beta-4target
ZonisamideAmine oxidase [flavin-containing] Atarget
ZonisamideCytochrome P450 2C19enzyme
ZonisamideUDP-glucuronosyltransferase 1-1enzyme
ZonisamideCytochrome P450 3A5enzyme
ZonisamideP-glycoprotein 1transporter
LurasidoneCytochrome P450 3A4enzyme
LurasidoneDopamine D2 receptortarget
Lurasidone5-hydroxytryptamine receptor 2Atarget
Lurasidone5-hydroxytryptamine receptor 7target
Lurasidone5-hydroxytryptamine receptor 1Atarget
LurasidoneAlpha-2C adrenergic receptortarget
LurasidoneAlpha-2A adrenergic receptortarget
InotersenTransthyretin mRNAtarget
AmisulprideDopamine D2 receptortarget
AmisulprideDopamine D3 receptortarget
Amisulpride5-hydroxytryptamine receptor 7target
Amisulpride5-hydroxytryptamine receptor 2Atarget
DisulfiramAldehyde dehydrogenase, mitochondrialtarget
DisulfiramCytochrome P450 2E1enzyme
DisulfiramDopamine beta-hydroxylasetarget
DisulfiramCytochrome P450 3A4enzyme
DisulfiramCytochrome P450 3A5enzyme
DisulfiramBile salt export pumptransporter
HydrochlorothiazideSolute carrier family 12 member 3target
HydrochlorothiazideSolute carrier family 22 member 6transporter
HydrochlorothiazideCalcium-activated potassium channel subunit alpha-1target
HydrochlorothiazideSerum albumincarrier
HydrochlorothiazideSolute carrier family 22 member 11transporter
HydrochlorothiazideMultidrug resistance-associated protein 4transporter
HydrochlorothiazideSolute carrier family 22 member 8transporter
DelafloxacinUDP-glucuronosyltransferase 1-1enzyme
DelafloxacinUDP-glucuronosyltransferase 1-3enzyme
DelafloxacinUDP-glucuronosyltransferase 2B15enzyme
DelafloxacinDNA topoisomerase 4 subunit Atarget
DelafloxacinDNA gyrase subunit Atarget
DelafloxacinCytochrome P450 2E1enzyme
DelafloxacinCytochrome P450 2C9enzyme
DelafloxacinCytochrome P450 3A4enzyme
DelafloxacinATP-binding cassette sub-family B member 5transporter
DelafloxacinATP-binding cassette sub-family G member 2transporter
DelafloxacinSerum albumincarrier
Farnesyl thiopyrophosphateDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)target
Farnesyl thiopyrophosphateGeranylgeranyl pyrophosphate synthasetarget
Farnesyl thiopyrophosphateMevalonate kinasetarget
Farnesyl thiopyrophosphateDehydrosqualene synthasetarget
EchothiophateCholinesterasetarget
EchothiophateSerum albumincarrier
MalathionCholinesterasetarget
MalathionCytochrome P450 1A2enzyme
MalathionCytochrome P450 2B6enzyme
Farnesyl diphosphateProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphatarget
Farnesyl diphosphateProtein farnesyltransferase subunit betatarget
Farnesyl diphosphateGTPase KRastarget
Farnesyl diphosphate2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthasetarget
Farnesyl diphosphateFarnesyl pyrophosphate synthasetarget
Farnesyl diphosphateDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)target
Farnesyl diphosphateLantibiotic nisin-Ztarget
Farnesyl diphosphateGeranylgeranyl pyrophosphate synthasetarget
Farnesyl diphosphate(2Z,6E)-farnesyl diphosphate synthasetarget
Farnesyl diphosphateGeranylgeranyl transferase type-2 subunit alphatarget
Farnesyl diphosphateGeranylgeranyl transferase type-2 subunit betatarget
Geranylgeranyl diphosphateProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphatarget
Geranylgeranyl diphosphateGeranylgeranyl transferase type-1 subunit betatarget
Geranylgeranyl diphosphateProtein farnesyltransferase subunit betatarget
Geranylgeranyl diphosphateGeranylgeranyl pyrophosphate synthasetarget
Geranylgeranyl diphosphateFarnesyl pyrophosphate synthasetarget
Geranylgeranyl diphosphateGeranylgeranyl transferase type-2 subunit alphatarget
Geranylgeranyl diphosphateGeranylgeranyl transferase type-2 subunit betatarget
DichlorvosSerum albumincarrier
DichlorvosSerotransferrintarget
DichlorvosCholinesterasetarget
TacrolimusPeptidyl-prolyl cis-trans isomerase FKBP1Atarget
TacrolimusCytochrome P450 3A4enzyme
TacrolimusCytochrome P450 3A5enzyme
TacrolimusP-glycoprotein 1transporter
TacrolimusATP-binding cassette sub-family A member 5transporter
TacrolimusSerum albumincarrier
TacrolimusAlpha-1-acid glycoprotein 1carrier
TacrolimusSolute carrier organic anion transporter family member 1B1transporter
TriclabendazoleCytochrome P450 1A2enzyme
TriclabendazoleCytochrome P450 2C9enzyme
TriclabendazoleExcretory Secretory (ES) proteinstarget
TriclabendazoleCytochrome P450 3A4enzyme
TriclabendazoleCytochrome P450 1A1enzyme
TriclabendazoleCytochrome P450 1B1enzyme
TriclabendazoleCytochrome P450 2C19enzyme
TriclabendazoleCytochrome P450 2D6enzyme
TriclabendazoleCytochrome P450 2A6enzyme
TriclabendazoleCytochrome P450 2C8enzyme
TriclabendazoleCytochrome P450 2B6enzyme
LopinavirHuman immunodeficiency virus type 1 proteasetarget
LopinavirCytochrome P450 3A4enzyme
LopinavirCytochrome P450 2D6enzyme
LopinavirCytochrome P450 2C19enzyme
LopinavirP-glycoprotein 1transporter
LopinavirCytochrome P450 2B6enzyme
LopinavirCytochrome P450 2C9enzyme
LopinavirCytochrome P450 3A Subfamilyenzyme
LopinavirSolute carrier organic anion transporter family member 1B1transporter
LopinavirSolute carrier organic anion transporter family member 1B3transporter
LopinavirBile salt export pumptransporter
LopinavirCytochrome P450 1A2enzyme
LopinavirAlpha-1-acid glycoprotein 1carrier
LopinavirSerum albumincarrier
ClofazimineCytochrome P450 3A4enzyme
ClofaziminePeroxisome proliferator-activated receptor gammatarget
ClofazimineCytochrome P450 2C8enzyme
ClofazimineCytochrome P450 2D6enzyme
ClofazimineCytochrome P450 3A5enzyme
ClofaziminePotassium voltage-gated channel subfamily A member 3target
ClofazimineSerum albumincarrier
ClofazimineP-glycoprotein 1transporter
ClofazimineATP-binding cassette sub-family G member 2transporter
ClofazimineMultidrug resistance-associated protein 1transporter
FostemsavirCytochrome P450 3A4enzyme
FostemsavirUDP-glucuronosyltransferases (UGTs)enzyme
FostemsavirP-glycoprotein 1transporter
FostemsavirATP-binding cassette sub-family G member 2transporter
FostemsavirSolute carrier organic anion transporter family member 1B1transporter
FostemsavirSolute carrier organic anion transporter family member 1B3transporter
FostemsavirSerum albumincarrier
FostemsavirEnvelope glycoprotein gp160target