Monoamine Oxidase Inhibitors

Name
Monoamine Oxidase Inhibitors
Accession Number
DBCAT001004  (DBCAT002868)
Description

A chemically heterogeneous group of drugs that have in common the ability to block oxidative deamination of naturally occurring monoamines. (From Gilman, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p414)

Drugs
DrugDrug Description
7,8-Dichloro-1,2,3,4-tetrahydroisoquinolinePotent reversible inhibitor of phenylethanolamine N-methyltransferase.
AmiflamineAmiflamine is a small molecule drug. Amiflamine has a monoisotopic molecular weight of 192.16 Da.
BenmoxinFor the treatment of depression.
BrofaromineNot Annotated
CaroxazoneFor the treatment of depression.
ClorgilineAn antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.
FurazolidoneA drug for the treatment of infectious diarrhea.
HarmalineNot Annotated
HarmineNot Available
HydracarbazineWas used for the treatment of hypertension .
IproniazidFor the treatment of depression (originally intended to treat tuberculosis).
IsocarboxazidA monoamine oxidase inhibitor used to treat enduring and debilitating symptoms of depression following inadequate clinical response to other antidepressant drugs.
LazabemideLazabemide is a small molecule drug. Lazabemide has a monoisotopic molecular weight of 199.05 Da.
LinezolidAn oxazolidinone antibiotic used to treat infections by susceptible strains of aerobic Gram-positive bacteria.
MebanazineFor the treatment of depression.
Methylene blueAn oxidation-reduction agent used for the treatment of pediatric and adult patients with acquired methemoglobinemia.
MilacemideMilacemide is a small molecule drug. Milacemide has a monoisotopic molecular weight of 144.13 Da.
MinaprineFor the treatment of depression
MoclobemideA monoamine oxidase inhibitor used in the treatment of major depressive disorder and bipolar disorder.
MofegilineMofegiline is a small molecule drug. The usage of the INN stem '-giline' in the name indicates that Mofegiline is a monoamine oxydase (MAO)-inhibitor type B. Mofegiline has a monoisotopic...
NialamideWithdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
OctamoxinFor the treatment of depression.
PargylineFor the treatment of moderate to severe hypertension.
PhenelzineA monoamine oxidase inhibitor used to treat atypical, nonendogenous, or neurotic depression.
PheniprazineFor the treatment of depression, schizophrenia, and angina pectoris.
PhenoxypropazineFor the treatment of depression.
PirlindoleFor the treatment of major depression. It is being studied in the treatment of fibromyalgia pain syndrome. One study determined that the effect of pirlindole on sensorimotor performance while driving...
PivhydrazineFor the treatment of depression.
ProcaineA local anesthetic used for anesthesia, peripheral nerve block, and spinal nerve block.
ProcarbazineAn antineoplastic agent indicated for the treatment of stage III and stage IV Hodgkin's disease in combination with other chemotherapeutic agents.
RasagilineAn irreversible inhibitor of monoamine oxidase used for the symptomatic management of idiopathic Parkinson's disease as initial monotherapy and as adjunct therapy to levodopa.
SafinamideA MAO-B inhibitor used as an add-on treatment to levodopa/carbidopa for Parkinson's disease during "off" episodes.
SafrazineFor the treatment of depression.
SelegilineA monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's.
ToloxatoneFor the treatment of major depressive disorder.
TranylcypromineA monoamine oxidase inhibitor used to treat major depressive disorder.
ViloxazineA selective norepinephrine reuptake inhibitor indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in adults in children.