Rabies (DBCOND0005273)

Identifiers

Synonyms

Rabies, unspecified / Rabies viral infections / Rabies virus infection / Rabies (disorder)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Rabies immune globulin, equine	Horse derived antibodies against rabies virus used in combination with a rabies vaccine for the treatment of rabies.	No drug targets
Rabies immune globulin, human	A solution of antibodies used to prevent rabies after an exposure.	Rabies Virus Proteinstarget
Rabies virus inactivated antigen, A	Rabies virus inactivated antigen, A is an inactivated virus vacine for the intramuscular injection. It is an active immunization against rabies that can be administered pre- or post-exposure to the...	No drug targets
Rabies virus inactivated antigen, B	Inactivated rabies virus antigen B is indicated for pre- and post-exposure prophylaxis against rabies.	No drug targets

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT02559921	Safety and Immunogenicity Study of Recombinant Human Rabies Immunoglobin (rhRIG) in Combination With Rabies Vaccine for Human Use With Human Rabies Immune Globulin (HRIG) in Combination With Rabies Vaccine for Human Use in Healthy Adult Subjects.	No drug interventions	prevention	2	completed
NCT04644484	A Phase III Clinical Study to Evaluate SYN023's Efficacy and Safety	Rabies immune globulin, human Rabies virus inactivated antigen, A	prevention	3	completed
NCT01466387	A Phase 3b, Randomized, Open-Label Study to Evaluate the Safety and Immunogenicity of Select Travel Vaccines When Administered Concomitantly With MenACWY in Adults	Japanese encephalitis virus strain sa 14-14-2 antigen (formaldehyde inactivated) Rabies virus inactivated antigen, A Typhoid Vi polysaccharide vaccine Yellow fever vaccine	prevention	3	completed
NCT00825305	Safety and Immunogenicity (Non-inferiority) of a Purified Chick Embryo Cell Vaccine Vaccine Administered in Two Different Schedules (Conventional Versus Abbreviated Schedule)	Rabies virus inactivated antigen, A	prevention	3	completed
NCT02657161	Safety and Efficacy of a PIKA Rabies Vaccine Containing the PIKA Adjuvant	PIKA rabies vaccine Rabies immune globulin, human	prevention	1	completed
NCT01286493	Immune Response After Booster Vaccination in HIV - Infected Patients Who Received Rabies Primary Vaccination	No drug interventions	treatment	Not Available	completed
NCT02564471	Effect of Antimalarial Drugs to Rabies Vaccine for Post-exposure Prophylaxis.	Atovaquone Chloroquine Doxycycline Proguanil Rabies immune globulin, human Rabies virus inactivated antigen, A	basic_science	4	completed
NCT02238756	Safety and Tolerability of CV8102 Alone and in Combination With a Rabies Virus Vaccine in Healthy Adults	CV-8102 Rabies immune globulin, human	prevention	1	completed
NCT01388985	Simplifying the Rabies Pre-exposure Vaccination	Rabies virus inactivated antigen, A	prevention	3	completed
NCT01641315	Immunogenicity Study of a Reduced (4-dose) Vaccine Schedule and Rabies Immunoglobulins	Rabies virus inactivated antigen, A	prevention	Not Available	completed
NCT05937113	Safety and Immunogenicity of the Inactivated Rabies Vaccine RABIVAX-S Administered Intramuscularly and Intradermally	Rabies virus inactivated antigen, B	prevention	4	completed
NCT03524417	Effect of ERIG Injection on Day 7 After First Dose of Rabies Vaccination to Rabies Immune Response	No drug interventions	treatment	Not Available	unknown_status
NCT02281396	The Safety Research of Freeze-dried Rabies Vaccine（MRC-5 Cell) in Chinese Humans	Rabies virus inactivated antigen, A	prevention	1	completed
NCT03713086	A Study to Assess the Safety, Reactogenicity and Immune Response of CureVac's Candidate Rabies mRNA Vaccine in Healthy Adults	Rabies immune globulin, human Rabies virus inactivated antigen, A	prevention	1	completed
NCT01930357	Purified Vero Rabies Vaccine-Serum Free Compared to Human Diploid Cell Vaccine in a Pre-exposure Prophylaxis Regimen	Aloe vera leaf Ascorbic acid Glycerin Nicotinamide Rabies virus inactivated antigen, A Vitamin A	prevention	2	completed
NCT02139657	An Open-label, Single-Arm Study to Evaluate the Safety and Rabies Virus Antibody Titers of Intramuscularly Administered Rabies Immune Globulin (Human)	Rabies immune globulin, human	treatment	1	completed
NCT05667974	A Study to Evaluate a PIKA Rabies Vaccine（Vero Cell）for Human Use,Freeze-dried	PIKA rabies vaccine Rabies virus inactivated antigen, A	prevention	3	active_not_recruiting
NCT01784874	Comparison of Purified Vero Rabies Vaccine, Serum Free With Human Diploid Cell Vaccine in Pre-exposure Use	Aloe vera leaf Ascorbic acid Glycerin Nicotinamide Rabies virus inactivated antigen, A Vitamin A	prevention	2	completed
NCT01365494	Immunogenicity and Safety of Rabies Vaccine, Administered With Two Different Simulated Post Exposure Schedules	Rabies virus inactivated antigen, A	prevention	4	completed
NCT01610362	Human Rabies Immunoglobulin (HRIG)- Dosage Determination and Interference With the Active Immune Response	Rabies immune globulin, human	treatment	Not Available	completed
NCT01622062	Immunogenicity and Safety of Verorab® in a "One-week" Intradermal Post-exposure Prophylaxis Regimen	Rabies virus inactivated antigen, B	treatment	3	completed
NCT06132789	A Clinical Trial of Rabies Vaccine（Human Diploid Cell）for Human Use,Freeze-dried in a Population Aged 10-60 Years	Rabies virus inactivated antigen, A	prevention	1	active_not_recruiting
NCT01339312	Study of the Purified Vero Rabies Vaccine - Serum Free in Comparison With the Reference Purified Vero Rabies Vaccine	Aloe vera leaf Ascorbic acid Glycerin Nicotinamide Rabies virus inactivated antigen, A Rabies virus inactivated antigen, B Vitamin A	prevention	3	completed
NCT02040090	Phase II/III Study of the Safety and Effectiveness of HRIG With Active Rabies Vaccine in Healthy Subjects	Rabies immune globulin, human Rabies virus inactivated antigen, A	health_services_research	2 / 3	completed
NCT02956421	Efficacy and Safety of a PIKA Rabies Vaccine Containing the PIKA Adjuvant With an Accelerated Regimen	PIKA rabies vaccine Rabies immune globulin, human	prevention	2	completed
NCT00703521	Rabies Immunization Concomitant With JEV in Children	Rabies virus inactivated antigen, A	prevention	2	completed
NCT03729102	Immunological Tolerance After Frequent Rabies Booster Vaccinations	Rabies virus inactivated antigen, A	treatment	Not Available	unknown_status
NCT01173302	Persistence of Rabies Antibody 1-5 Years After the Post-exposure Prophylaxis With Vero Cell Antirabies Vaccine and Antibody Response to a Single Booster Dose	Rabies virus inactivated antigen, A	health_services_research	4	unknown_status
NCT00708084	Randomized Phase II Trial on Safety and Neutralizing Activity of CL184 and Rabies Vaccine Versus Human Rabies Immune Globulin (HRIG) and Rabies Vaccine in Children and Adolescents	No drug interventions	treatment	2	completed
NCT01067079	Single Center, Open Label, Follow up Study in Subjects Who Previously Received Rabies Vaccine as Simulated Post-Exposure Regimen	No drug interventions	Not Available	Not Available	terminated
NCT05453487	Immunogenicity and Safety of an Inactivated SARS-CoV-2 Vaccine (Sinopharm BBIBP-CorV) Coadministered With Rabies Vaccine	Rabies virus inactivated antigen, A	prevention	4	unknown_status
NCT00260351	Immunogenicity and Safety of Verorab™ in Indian Population	Rabies virus inactivated antigen, A	treatment	4	completed
NCT01137045	Immunogenicity and Safety Study of A New Chromatographically Purified Vero Cell Rabies Vaccine With ID Regimen and ERIG	Rabies virus inactivated antigen, B	treatment	4	completed
NCT03093545	Effect of Rabies Immunoglobulin on Immunogenicity of Post-exposure Rabies Vaccination in Obese Patients	Rabies immune globulin, equine Rabies virus inactivated antigen, A	treatment	Not Available	completed
NCT02912845	Post-marketing Study of KamRAB Administered as a Single Dose With Active Rabies Vaccine in Children Exposed to Rabies	Rabies immune globulin, human	treatment	3	completed
NCT00656097	A Randomized Phase II Trial to Compare the Safety and Neutralizing Activity of CL184 in Combination With Rabies Vaccine vs. HRIG or Placebo in Combination With Rabies Vaccine in Healthy Adult Subjects	No drug interventions	treatment	2	completed
NCT01228383	Rabies Virus Neutralizing Activity and Safety of CL184, a Monoclonal Antibody Cocktail, in Simulated Rabies Post-Exposure Prophylaxis in Healthy Adults	Rabies immune globulin, human Rabies virus inactivated antigen, A	treatment	2	completed
NCT03774628	Immunity Duration of Rabies Vaccine and Booster Dose Effects at 10 Years Post-primary Vaccination	No drug interventions	prevention	Not Available	completed
NCT05547815	Observation on the Immune Persistence of People Aged 10-60 Years Old Immunized With Five Doses of Rabies Vaccine	No drug interventions	prevention	4	completed
NCT04162600	Safety and Immunogenicity of the Candidate Rabies Vaccine ChAdOx2 RabG	Rabies virus inactivated antigen, A	treatment	1	unknown_status
NCT02491541	A Phase 3 Clinical Trial for a Rabies Vaccine (Vero Cell) for Human Use in Healthy Chinese Subjects	No drug interventions	prevention	3	completed
NCT02545517	A Phase 3 Clinical Trial to Evaluate Long-term Immunogenicity and Boostability of Purified Chick-Embryo Cell Rabies Vaccine in Adults Following Primary Series of Pre/Exposure Prophylaxis.	Rabies immune globulin, human Rabies virus inactivated antigen, A	prevention	3	completed
NCT01680016	A Randomized, Open-label Study Comparing Two Different Rabies Vaccine Schedules in Chinese Children and Older Adults	No drug interventions	prevention	3	completed
NCT05350735	Phone Text Message Reminders on Compliance With Human Rabies Post Exposure Prophylaxis Project	No drug interventions	treatment	Not Available	completed
NCT02241135	RNActive® Rabies Vaccine (CV7201) in Healthy Adults	No drug interventions	prevention	1	completed
NCT04829630	Immunity Persistence After Abridged Intradermal Rabies PEP	Rabies virus inactivated antigen, A	other	Not Available	completed
NCT05969626	Clinical Trial of Freeze-dried Human Rabies Vaccine (Without Serum Vero Cells)	No drug interventions	prevention	3	not_yet_recruiting
NCT02547727	Immune Responses After a Four-site Intradermal Rabies Booster Vaccination in HIV-infected Adults	Rabies virus inactivated antigen, A	treatment	Not Available	unknown_status
NCT00694460	Evalution of Immunogenicity, Safety and Booster Response of a Rabies Vaccine Administered Concomitantly With Japanese Encephalitis Vaccine in Toddlers	Rabies virus inactivated antigen, A	prevention	2	completed
NCT04019444	Dosage-Escalation Study of the Safety and Immunogenicity of a Novel Rabies Vaccine ChAd155-RG vs. the Comparator RABAVERT Vaccine in Healthy Adult Subjects	Rabies virus inactivated antigen, A	prevention	1	completed
NCT06433440	Safety and Immunogenicity of Purified Verocell Rabies Vaccine PVRV Administered Intramuscularly and Intradermally	No drug interventions	prevention	4	completed
NCT01662440	Safety and Immunogenicity of 2 Different Vaccination Schedules of Rabies and Japanese Encephalitis Vaccines in Healthy Adult Subjects	No drug interventions	prevention	3	completed
NCT01063140	Rabies Immune Plasma Booster Study	Rabies immune globulin, human Rabies virus inactivated antigen, A	Not Available	Not Available	completed
NCT00948272	Study of Purified Vero Rabies Vaccine Serum Free Compared With Reference Purified Vero Rabies Vaccine in Healthy Adults	Aloe vera leaf Ascorbic acid Glycerin Nicotinamide Rabies virus inactivated antigen, A Vitamin A	prevention	2	completed
NCT02729168	Safety Study of Rabies Vaccine INDIRAB® Five Doses (0.5ml) Post Exposure Administered Intramuscularly	Rabies virus inactivated antigen, A	prevention	Not Available	completed
NCT03228069	Immune Responses and Immunological Tolerance After Rabies Booster Vaccination in HIV-infected Adults	No drug interventions	treatment	Not Available	unknown_status
NCT01877395	Study of Purified Vero Rabies Vaccine and Rabies Human Diploid Cell Vaccine in a Simulated Rabies Post-exposure Regimen	Rabies virus inactivated antigen, A	prevention	2	completed
NCT02374814	Immunogenicity of Rabies Vaccine for Pre Exposure Prophylaxis	Albumin human Rabies immune globulin, human Rabies virus inactivated antigen, A	basic_science	4	completed
NCT03961555	Comparison of SYN023 to Human Rabies Immune Globulin in Post Exposure Prophylaxis of Rabies	Rabies immune globulin, human Rabies virus inactivated antigen, A	prevention	2	completed
NCT05382650	Survey of Human Rabies Immune Globulin Safety in Children	Rabies immune globulin, human	Not Available	Not Available	recruiting
NCT04213950	Improving Adherence to Rabies PEP Guideline Recommendations	No drug interventions	health_services_research	Not Available	completed
NCT05702008	Social Media as an Information, Education and Communication Tool for Rabies Prevention: An Interventional Study	No drug interventions	prevention	Not Available	completed
NCT04270838	A Phase Ib/II Study of the Safety and Immunogenicity of the Candidate Rabies Vaccine ChAdOx2 RabG	Rabies virus inactivated antigen, A	treatment	1 / 2	active_not_recruiting