NCT04943302
Isatuximab and Bendamustine in Systemic Light Chain Amyloidosis treatment 2 withdrawn NCT03201965
A Study to Evaluate the Efficacy and Safety of Daratumumab in Combination With Cyclophosphamide, Bortezomib and Dexamethasone (CyBorD) Compared to CyBorD Alone in Newly Diagnosed Systemic Amyloid Light-chain (AL) Amyloidosis treatment 3 active_not_recruiting NCT05250973
A Study of Daratumumab-Based Therapies in Participants With Amyloid Light Chain (AL) Amyloidosis treatment 2 recruiting NCT02909036
Study of Captisol Enabled Melphalan and Pharmacokinetics for Patients With Multiple Myeloma or Light Chain Amyloidosis That Are Receiving an Autologous Transplant. treatment 1 active_not_recruiting NCT04769479
A Single Dose Study to Evaluate the Pharmacokinetics of Acoramidis Modified Release Formulations in Healthy Subjects treatment 1 completed NCT05199337
Phase 1/2 Study of ZN-d5 for the Treatment of Relapsed or Refractory Light Chain (AL) Amyloidosis No drug interventions treatment 1 / 2 completed NCT06414746
Hereditary Transthyretin Amyloidosis Polyneuropathy in Patients With Carpal Tunnel Syndrome in Russia No drug interventions Not Available Not Available recruiting NCT06573723
Institutional Registry of Rare Diseases No drug interventions Not Available Not Available recruiting NCT02716103
Assessment of Minimal Residual Disease (MRD) After Antineoplastic Treatment in Patients With AL Amyloidosis No drug interventions Not Available Not Available completed NCT05260203
MargheRITA (Remote Intelligence for Therapeutic Adherence) No drug interventions supportive_care Not Available completed NCT02792790
Carpal Tunnel Syndrome and Amyloid Cardiomyopathy No drug interventions Not Available Not Available completed NCT06527521
Prevalence of Amyloidosis in Trauma Patients No drug interventions Not Available Not Available not_yet_recruiting NCT05375279
A PILOT Study on LSGB vs EMB in the Diagnosis of Cardiac Transthyretin Amyloidosis No drug interventions Not Available Not Available unknown_status NCT04913454
CLearing Alzheimer's Disease Molecular Pathology Without Medications No drug interventions treatment Not Available unknown_status NCT03044353
Multiple Treatment Session Study to Assess GSK2398852 Administered Following and Along With GSK2315698 treatment 2 terminated NCT04068077
Application of High Resolution Optical Coherence Tomography in Skin Disease: Amyloidosis and Differential Diagnosis No drug interventions Not Available Not Available completed NCT01215747
Efficacy and Safety Study of KIACTA in Preventing Renal Function Decline in AA Amyloidosis prevention 3 completed NCT05738005
Dietary Reporting In The Amyloidoses No drug interventions health_services_research Not Available recruiting NCT02510261
The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Participants Who Have Already Been Treated With ALN-TTR02 (Patisiran) treatment 3 completed NCT05556928
Cancer and Aging Resilience Evaluation in Older Adults With Hematologic Malignancies: The CARE-Heme Registry No drug interventions Not Available Not Available recruiting NCT00186407
Autologous Stem Cell Rescue for Primary Amyloidosis No drug interventions treatment 2 completed NCT01527032
Risk-adapted Therapy for Primary Systemic (AL) Amyloidosis treatment 2 completed NCT00890552
A Pilot Study of Lenalidomide, Melphalan and Dexamethasone in AL Amyloidosis treatment Not Available completed NCT00621400
Lenalidomide in Combination With Melphalan and Dexamethasone in Newly-diagnosed Light-chain (AL)-Amyloidosis treatment 1 / 2 completed NCT01383759
Bortezomib/Dexamethasone (BD), Followed By Autologous Stem Cell Transplantation and Maintenance Bortezomib/Dexamethasone For the Initial Treatment of Monoclonal Immunoglobulin Deposition Disease (MIDD) Associated With Multiple Myeloma and AL Amyloidosis treatment Not Available completed NCT03567499
Pro-arrhythmic Potential of GSK3039294 in Healthy Subjects No drug interventions treatment 1 withdrawn NCT03168906
Renal AL Amyloid Involvement and NEOD001 treatment 2 terminated NCT03825406
Prevalence of Wildtype Amyloid After TAVR No drug interventions Not Available Not Available withdrawn NCT01864018
Ixazomib With Cyclophosphamide and Dexamethasone in Patients With Previously Untreated Symptomatic Multiple Myeloma or Light Chain Amyloidosis treatment 1 / 2 active_not_recruiting NCT03825224
Evaluation of MyoStrain™ in Clinical Practice No drug interventions Not Available Not Available completed NCT03431896
Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis No drug interventions Not Available Not Available active_not_recruiting NCT03610035
A Study of NPT189 in Healthy Subjects No drug interventions treatment 1 completed NCT01677286
Safety and Effect of Doxycycline in Patients With Amyloidosis treatment 2 completed NCT00919139
S0309, Repository: Blood/Bone Marrow From Pts. With Myeloma, WM, Amyloidosis, or MGUS. No drug interventions Not Available Not Available completed NCT03584022
Clinical Trial to Assess the Safety of a Novel Scaffold Biomaterial No drug interventions other Not Available active_not_recruiting NCT04984330
Selinexor for Treatment of Light Chain Amyloidosis With Relapsed/Refractory Disease treatment 0 withdrawn NCT00298766
Open-Label Phase 1/2 Study of VELCADE for Injection in Patients With Light-chain (AL)-Amyloidosis treatment 1 / 2 completed NCT05635266
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives No drug interventions Not Available Not Available recruiting NCT02260466
Prevalence and Post-surgical Outcomes of CARdiac Wild-type TransthyrEtin amyloidoSIs in Elderly Patients With Aortic steNosis Referred for Valvular Replacement. No drug interventions screening Not Available active_not_recruiting NCT05793320
Carpal Tunnel Release With Risk Factors for Amyloidosis No drug interventions diagnostic Not Available recruiting NCT02627820
The Effect of an Antisense Oligonucleotide to Lower Transthyretin (TTR) Levels on the Progression of -Wild-type TTR Involving the Heart treatment 2 withdrawn NCT03923920
Screening for Systemic Amyloidosis Via the Ligamentum Flavum No drug interventions Not Available Not Available completed NCT04456582
Noninvasive Assessment of Myocardial Stiffness by 2D-SWE Ultrasound Technique (Bidimensional Shear Wave Elastography) in Patients With Transthyretin Amyloidosis No drug interventions diagnostic Not Available unknown_status NCT02574676
Quality of Life (QOL) Registry for Patients With AL Amyloidosis No drug interventions Not Available Not Available completed NCT02816476
Daratumumab Therapy for Patients With Refractory or Relapsed AL Amyloidosis treatment 2 completed NCT02589860
Analysis of Oral Mucositis in Patient's Undergoing Melphalan Conditioning and Autologous Stem Cell Transplant No drug interventions Not Available Not Available withdrawn NCT05010980
Early Detection of Cardiac Amyloidosis No drug interventions Not Available Not Available recruiting NCT03702829
24 Month Open Label Study of the Tolerability and Efficacy of Inotersen in TTR Amyloid Cardiomyopathy Patients treatment 2 unknown_status NCT03019029
Diagnostic Utility of F-18 Florbetapir PET/MR in Peripheral Nerve Amyloidosis No drug interventions diagnostic 1 / 2 completed NCT04893889
Substudy (NCT04456582): Noninvasive Assessment of Myocardial Stiffness by 2D-SWE Ultrasound Technique (Two-dimensional Shear Wave Elastography) in Patients With Amyloidosis and Fabry Disease. No drug interventions diagnostic Not Available unknown_status NCT03717844
Registry for Adults With Plasma Cell Disorders (PCD's) No drug interventions Not Available Not Available recruiting NCT01273844
Study of Bortezomib +HSCT in Primary Systemic Amyloidosis (AL) treatment Not Available completed NCT05950867
Prevalence of Wild-type TTR Cardiac Amyloidosis in Patients With Polyneuropathy of Unknown Cause. No drug interventions screening Not Available recruiting NCT02603172
A Safety Study of GSK3039294 in Healthy Volunteers and Patients With Systemic Amyloidosis No drug interventions treatment 1 terminated NCT02924272
Ixazomib Rollover Study treatment 2 completed NCT06539169
FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases No drug interventions Not Available Not Available recruiting NCT05235269
A Study to Evaluate Organ Level Uptake Repeatability of 124I AT-01 in Subjects With Systemic Amyloidosis diagnostic 2 completed NCT06563895
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant prevention 3 not_yet_recruiting NCT00186095
Mixed Chimeric Transplantation for Primary Amyloidosis No drug interventions treatment Not Available withdrawn NCT01406314
SAP Depleter Dose Assessment Study in Patients No drug interventions other 1 completed NCT02953808
Phase 1 Study of GSK2315698 in Healthy Japanese Subjects No drug interventions treatment 1 completed NCT00981708
Lenalidomide, Dexamethasone and Cyclophosphamide in Amyloidosis (AL) treatment 1 / 2 completed NCT02111538
Body Composition in Systemic Amyloidosis No drug interventions Not Available Not Available completed NCT01998503
Bortezomib and Dexamethasone Followed by ASCT Compared With ASCT Alone in Treating Patients With AL Amyloidosis treatment 3 completed NCT06571864
AL Amyloidosis and Anti-CD38-Daratunumab No drug interventions treatment Not Available completed NCT03984721
Amyloidosis Typing Using Mass Spectrometry-based Proteomics: a New Accurate Tool for Difficult Typing No drug interventions diagnostic Not Available completed NCT04636684
Prevalence and Significance of ATTR Aortic Valve Amyloidosis in Degenerative Aortic Stenosis No drug interventions prevention Not Available recruiting NCT03774784
A Study of the Natural History of Leukocyte Chemotactic Factor 2 Amyloidosis (ALECT2) Disease No drug interventions Not Available Not Available terminated NCT01432587
The Effect of Diflunisal on Familial Transthyretin Amyloidosis Not Available Not Available completed NCT04983433
Increasing Amyloidosis Awareness and Diagnosis Through Programmatic Imaging, Blood/Urine Testing and Pathology No drug interventions Not Available Not Available unknown_status NCT01347047
HIBA-Institutional Registry of Amyloidosis No drug interventions Not Available Not Available recruiting NCT04245098
Carpal Tunnel Syndrome and Amyloidosis No drug interventions diagnostic Not Available unknown_status NCT01737398
Efficacy and Safety of Inotersen in Familial Amyloid Polyneuropathy treatment 2 / 3 completed NCT05862961
Better Classification of Respiratory Amyloidosis No drug interventions Not Available Not Available not_yet_recruiting NCT02587728
Carpal Tunnel/Amyloidosis Blood Sample Study No drug interventions Not Available Not Available completed NCT05758493
Characterizing Iodine-124 Evuzumitide (AT-01) in Systemic Amyloidosis No drug interventions diagnostic 2 recruiting NCT05283993
A Cohort Study of Plasma Cell Disorders (PCDs) in PKUFH No drug interventions Not Available Not Available recruiting NCT03879278
Multiple Ascending Dose Study in Healthy Subjects No drug interventions treatment 1 terminated NCT06251778
NatiOnal Referral cenTEr Study of Transthyretin Amyloid Cardiomyopathy(ATTR) Patients on Tafamidis No drug interventions Not Available Not Available recruiting NCT02590588
Idelalisib for Immunoglobulin M (IgM)-Associated Primary (AL) Amyloidosis treatment 2 terminated NCT02545907
A Dose Escalation Study of Carfilzomib Taken With Thalidomide and Dexamethasone in Relapsed AL Amyloidosis treatment 1 / 2 completed NCT01323985
SAP Depleter Dose Escalation Study in Healthy Volunteers No drug interventions treatment 1 completed NCT02158052
Combined Bone Marrow and Renal Transplantation for Hematologic Disorders With End Stage Renal Disease treatment Not Available completed NCT04661800
Study of Olfactory Disorders in Patients With Cardiac Amyloidosis No drug interventions screening Not Available unknown_status NCT01789242
A Safety Study of Carfilzomib in Patients With Previously-Treated Systemic Light Chain Amyloidosis treatment 1 completed NCT05754099
Identification of Clinically Significant Markers of ATTRv in Pre-symptomatic Mutation Carriers. No drug interventions Not Available Not Available recruiting NCT01135849
B-Receptor Signaling in Cardiomyopathy No drug interventions Not Available Not Available completed NCT02485613
Bortezomib for Immunoglobulin Light Chain(AL) Amyloidosis Not Available Not Available completed NCT00166413
Efficacy of CC-5013 (Revlimid or Lenalidomide) in Patients With Primary Systemic Amyloidosis treatment 2 completed NCT02462213
Prospective Identification of Cardiac Amyloidosis by Cardiac Magnetic Resonance Imaging No drug interventions Not Available Not Available withdrawn NCT05577819
Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF No drug interventions diagnostic Not Available recruiting NCT05263817
A Clinical Study of CD19/BCMA CAR-T Cells in the Treatment of Refractory POEMS Syndrome, Amyloidosis, Autoimmune Hemolytic Anemia, and Vasculitis No drug interventions treatment 0 recruiting NCT02055534
Nutritional Counseling in Systemic Immunoglobulin Light-chain Amyloidosis No drug interventions treatment Not Available completed NCT04985734
Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM) in Patients With Idiopathic Peripheral Neuropathy No drug interventions diagnostic Not Available not_yet_recruiting NCT01083316
Bortezomib and Dexamethasone Followed by High-Dose Melphalan and Stem Cell Transplantation for Primary (AL) Amyloidosis treatment 2 completed NCT05145816
Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis treatment 1 / 2 recruiting NCT03959358
A Study to Desensitize Allergic Reactions to Treatments for Blood Disorders treatment 2 completed NCT03860935
Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy treatment 3 completed NCT02187263
German Centre for Cardiovascular Research Cardiomyopathy Register No drug interventions Not Available Not Available unknown_status NCT03417830
Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging diagnostic 1 terminated NCT03130348
Ibrutinib With or Without Bortezomib and Dexamethasone in Treating Patients With Relapsed or Refractory Immunoglobulin Light Chain Amyloidosis treatment 2 withdrawn NCT00004374
Study of Systemic Amyloidosis Presentation and Prognosis No drug interventions Not Available Not Available unknown_status NCT04869631
Screening for Amyloidosis Before Aortic Valve Elective Replacement No drug interventions Not Available Not Available active_not_recruiting NCT02791373
Vinorelbine and Gemcitabine in Myeloma treatment 2 completed NCT02338427
Capacity of Amylose Characterisation Compare by Immunohistochemistry and Proteomic Analysis No drug interventions diagnostic Not Available completed NCT01606280
Long-term Outcomes of Patients With Primary Amyloidosis After Stem Cell Transplantation No drug interventions Not Available Not Available completed NCT00017680
Study of High-Dose Melphalan and Autologous Stem Cell Transplantation in Patients With Primary Light Chain Amyloidosis treatment 2 completed NCT03123029
Expanded Access to Venetoclax Not Available Not Available available NCT04265040
DZHK TORCH-Plus is a Registry for Patients With Cardiomyopathies and Serves as Source for Cardiovascular Research Studies No drug interventions Not Available Not Available recruiting NCT02245867
Study of Chimeric Fibril-Reactive Monoclonal Antibody 11-1F4 in Patients With AL Amyloidosis treatment 1 completed NCT04942067
APG-2575 in Combination With Novel Therapeutic Regimens in Subjects With Relapsed or Refractory Multiple Myeloma treatment 1 / 2 recruiting NCT02175004
Extension Study Assessing Long Term Safety and Efficacy of IONIS-TTR Rx in Familial Amyloid Polyneuropathy (FAP) treatment 3 completed NCT05259072
carDIo-ttranSSfOrm nucLEar Imaging Study No drug interventions other 3 recruiting NCT02555969
Minimal Residual Disease as a Possible Predictive Factor for Relapse in Patients With AL Amyloidosis No drug interventions Not Available Not Available completed NCT00607581
Cyclophosphamide, Lenalidomide and Dexamethasone (CLD) for Previously Treated Patients With AL Amyloidosis treatment 2 completed NCT03886155
Cardiac Amyloidosis Screening at Trigger Finger Release No drug interventions Not Available Not Available completed NCT01777243
A Study to Evaluate the Safety of GSK2398852 When Co-administered With GSK2315698 in Patients With Systemic Amyloidosis treatment 1 completed