Pruritus (DBCOND0019903)

Identifiers

Synonyms
Itchiness / Itching sensation / Itch / Itching / Pruritis/itching / Pruritis / Pruritus, unspecified / Itching of skin (finding) / Itching (finding) / Pruritus NOS / Itch of skin (observable entity) / Pruritus cutaneous / Itchy skin / Itchy

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Alimemazine
An antihistamine agent used to prevent and relieve allergic conditions which cause pruritus and other allergic skin conditions, including urticaria.
Amcinonide
A topical corticosteroid used in the treatment of inflammation and pruritus due to a variety of dermatoses.
Bamipine
An H1 antihistamine used topically to relieve mild to moderate symptoms associated with insect bites.
No drug targets
Bepotastine
An ophthalmic H1 antagonist used to treat itchiness associated with allergic conjunctivitis.
Betamethasone
A systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
Budesonide
A corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis.
Centella asiatica
Centella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
No drug targets
Cetrimonium
A compound that can be used as a topical antiseptic.
Chlorpheniramine
A histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies.
Cholestyramine
A bile acid sequestrant used as an adjunct in the reduction of elevated serum cholesterol in patients with primary hypercholesterolemia, and for the relief of pruritus associated with partial biliary obstruction.
Cyproheptadine
A combined serotonin and histamine antagonist used in the treatment of allergic symptoms, for appetite stimulation, and off-label in the treatment of serotonin syndrome.
Dexchlorpheniramine
A chlorpheniramine enantiomer antihistamine indicated in the treatment of sunburns, insect bites, and allergic reactions of the skin.
Dexpanthenol
An alcoholic analogue of D-pantothenic acid that is used as a supplement or application to support a healthy epithelium and is also used to prevent vitamin deficiency in patients receiving total parenteral nutrition (TPN).
No drug targets
Diphenhydramine
A H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.
Doxepin
A psychotropic agent used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia.
Fluconazole
A triazole antifungal used to treat various fungal infections including candidiasis.
Fluocinolone acetonide
A corticosteroid used to treat skin conditions, eczematous otitis externa, diabetic macular edema, and non-infectious uveitis of the posterior segment of the eye.
Fluocinonide
A high potency corticosteroid commonly used topically for a number of inflammatory skin conditions.
Hyaluronic acid
A glycosaminoglycan used for the relief of joint pain, wound healing, ophthalmologic treatment, cosmetic treatment, and various other applications.
Hydrocortisone acetate
A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses and ulcerative colitis.
Hydroxyzine
An antihistamine used to treat anxiety and tension associated with psychoneuroses, as well as allergic conditions such as pruritus and chronic urticaria.
Loratadine
A second generation antihistamine used to manage the symptoms of allergic rhinitis.
Mometasone
A corticosteroid with no indications.
Mometasone furoate
A corticosteroid used to treat asthma, allergic rhinitis, nasal congestion, nasal polyps, dermatitis, and pruritus.
Naloxone
An opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection.
Odevixibat
An ileal sodium/bile acid cotransporter inhibitor indicated in the treatment of pruritus in patients with progressive familial intrahepatic cholestasis.
Oxatomide
An antihistamine indicated in the treatment and prevention of allergic symptoms.
Pine tar
A medication indicated in itchy, inflamed, and flaky skin conditions.
No drug targets
Prednisolone
A glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
Rupatadine
A selective histamine H1 receptor antagonist and platelet activating factor (PAF) antagonist used to treat allergic rhinitis.
Salicylic acid
An acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
Synthetic camphor
Not Annotated
No drug targets
Zinc acetate
A medication used to treat zinc deficiency.
Zinc oxide
A mineral ingredient of various pharmacological preparations to treat diaper dermatitis and other skin conditions, to protect the epidermis, and to prevent sunburn.
No drug targets
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02168634
The Use of Botulinum Toxin in the Treatment of Itching From Hypertrophic Scar -- A Randomised Controlled TrialNo drug interventionstreatmentNot Availableunknown_status
NCT06245564
Effect of Ketamine, Amitriptyline and Their Combination on Histaminergic and Non-histaminergic Itchbasic_scienceNot Availablenot_yet_recruiting
NCT05249387
Characterization of Bovine Adrenal Medulla as a New Surrogate Model of Non-histaminergic ItchNo drug interventionsbasic_scienceNot Availablecompleted
NCT04635254
The Effect of Halophyte-based Cream on Pain and ItchNo drug interventionsbasic_scienceNot Availablecompleted
NCT04387851
Learning Mechanisms for Placebo and Nocebo Studies on Somatosensory Sensations: a Systematic Review and Meta-analysis.No drug interventionsNot AvailableNot Availablecompleted
NCT05024851
Psychogenic and Neurogenic Components in Patients With Psychogenic or Neuropathic PruritusNo drug interventionsNot AvailableNot Availableterminated
NCT03576053
A Mechanistic Evaluation of the Interactions Between Thermoceptive and Pruriceptive Sensory Processingbasic_scienceNot Availablecompleted
NCT04554888
Characterization of New Human Models of Non-histaminergic Itch and Their Interaction With the TRPM8 Receptorbasic_scienceNot Availablecompleted
NCT04700007
Evaluation of Peripheral Itch Mechanisms Following Injection of Morphine (Second Sub-Project)basic_scienceNot Availablecompleted
NCT04515056
Characterization of New Human Models of Non-histaminergic Itchbasic_scienceNot Availablecompleted
NCT06201715
Efficacy and Safety of Tofacitinib in Patients With Prurigo NodularistreatmentNot Availablenot_yet_recruiting
NCT04588532
Characterization of BAM8-22 as a New Surrogate Model of Non-histaminergic Itchbasic_scienceNot Availablecompleted
NCT02075632
Study to Evaluate Product Duration of Use Experience With Alclometasone Dipropionate Creamtreatment2completed
NCT01683552
Aprepitant in the Management of Biological Therapies-related Severe Pruritussupportive_care2completed
NCT04858360
Inhibition of Non-histaminergic Pruritus Applied Using 3 Different Pruritogensbasic_scienceNot Availablecompleted
NCT06503510
Role of Interleukin-13 Pathways on Pain and Itch SensitivityNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT06503523
The Effects of Performing a Motor Imagery Task on Cortical Excitability During Acute Experimental Muscle Pain and Acute ItchNo drug interventionsbasic_scienceNot Availablenot_yet_recruiting
NCT03928223
The Color of Itch; Itch Modification by Color ViewingNo drug interventionsNot AvailableNot Availablecompleted
NCT04613102
The Efficacy and Safety of 3% Cannabidiol (CBD) Cream in Patients With Epidermolysis Bullosa: A Phase II/III Trialtreatment2 / 3withdrawn
NCT02828787
Central Mechanisms of Chronic Pruritus: Functional and Structural Brain Imaging.No drug interventionsdiagnosticNot Availableterminated
NCT05195177
Testing Protocol to Efficiently Induce Itchbasic_scienceNot Availableenrolling_by_invitation
NCT05460598
The Effect of Cooling With a Bed Topper and Linen on Itch in Clinical RoutineNo drug interventionsotherNot Availablecompleted
NCT03928093
Pregabalin Treatment for RDEB Pain and Itchtreatment3completed
NCT03943407
Characterization of the Toll-like Receptor 7-agonist Imiquimod 3.75% as a New Surrogate Model of Itchbasic_scienceNot Availablewithdrawn
NCT05678309
Establishment of a Patient Library in Patients With Pruritus Sine MateriaNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06470737
Investigation of Corticospinal Excitability Aspects of Itch and PainNo drug interventionsbasic_scienceNot Availablenot_yet_recruiting
NCT03239106
A Study Examining the Medication Apremilast as Treatment for Chronic Itchtreatment2completed
NCT04076865
Evaluation of the Effect Induced by Repeated Administration of Topical Local Anaesthetic (EMLA) on Itchbasic_scienceNot Availablecompleted
NCT04115462
A Relation of Morphine-induced Itch and Pain Processingbasic_scienceNot Availablecompleted
NCT06036589
Characterization of Bovine Adrenal Medulla as a Model of Non-histaminergic ItchNo drug interventionsbasic_scienceNot Availablecompleted
NCT04711044
Investigation of a New Human Model for ItchNo drug interventionsbasic_scienceNot Availablecompleted
NCT04197440
Characterization of Bovine Adrenal Medulla (BAM8-22) as a New Surrogate Model of Non-histaminergic ItchNo drug interventionsbasic_scienceNot Availableunknown_status
NCT04289038
The Efficacy of VR and AR on PruritusNo drug interventionssupportive_careNot Availablecompleted
NCT03901443
Survey on Itch in Outpatients of a University ClinicNo drug interventionsNot AvailableNot Availablecompleted
NCT00330343
Optimal Dose of Prophylactic Naloxone in Reducing Opioid-Induced Side Effects in Children/Adolescentstreatment2completed
NCT05356403
CR845-310302: A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritustreatment3terminated
NCT04510090
Evaluate the Safety, Tolerability, and PK of EP547 in Healthy Subjects and Subjects With Cholestatic or Uremic PruritusNo drug interventionstreatment1completed
NCT00261079
Fexofenadine in Pruritic Skin Diseasetreatment4completed
NCT04999787
A Clinical Trial Evaluating the Efficacy, Safety, and Pharmacokinetics of HSK21542 Injection in Liver Disease Subjects With PruritusNo drug interventionstreatment2completed
NCT00323154
Nalbuphine for the Treatment of Opioid Induced Pruritus in Childrentreatment3completed
NCT00693654
Comparative Study of the Efficacy of SARNA Sensitive Lotion for Treatment of Uremic Itch in Adult Hemodialysis Patientstreatment4completed
NCT03997851
Topical Acetaminophen for Itch Relief: a Proof of Concept Study in Healthy Subjectstreatment1 / 2completed
NCT03490877
Scratch and Sleep Quantification in Atopic DermatitisNo drug interventionsNot AvailableNot Availablecompleted
NCT04396977
Inter-arm and Inter-period Reproducability of the Dermal Blood Flow Response After a Histamine Skin Prick.No drug interventionsbasic_scienceNot Availablecompleted
NCT02475447
Safety, Pharmacokinetics and Preliminary Efficacy of Asimadoline in Pruritus Associated With Atopic Dermatitistreatment2completed
NCT02654483
Neurokinin-1 Receptor Antagonist for the Treatment of Itch in EB Patientstreatment2completed
NCT00762983
Observation of Use of Claritin (Loratadine) Tablet, RediTabs, and Dry Syrup in Children (Study P05834)(COMPLETED)Not AvailableNot Availablecompleted
NCT03798561
Study to Evaluate ASN008 Topical Gel (TG)No drug interventionstreatment1completed
NCT03701971
Study Evaluating the Benefit of Music Therapy on Pruritus in Patients With Pruritic DermatitisNo drug interventionsotherNot Availablecompleted
NCT02975271
Study of the Efficacy, Safety & Tolerability of Serlopitant for Pruritus (Itch) After Burn Injurytreatment2terminated
NCT02277678
Comparison of Epidural Oxycodone and Epidural Morphinetreatment3completed
NCT03673878
Prevalence of a Localized or Diffuse Pruritus in a Population With One or Several, Primitive or Secondary, Brain Tumor(s)No drug interventionsNot AvailableNot Availablecompleted
NCT06446609
Drug-induced Liver Injury: Itching StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT05461456
Bioavailability and Tolerability of Fexofenadine Hydrochloride Topical Lotion 1%treatment1completed
NCT01232985
Efficacy and Tolerability Study of Device, RD047-26 for the Treatment of Mild to Moderate Atopic Dermatitis in AdultsNo drug interventionstreatment2completed
NCT02639052
Itch Relieving Effect of Botox: a Study in Healthy Subjectstreatment1 / 2completed
NCT01236859
Gabapentin for Prophylaxis Intrathecal Morphine-Induced PrurituspreventionNot Availablecompleted
NCT04256759
Dupilumab for the Treatment of Moderate to Severe Chronic Hepatic Pruritustreatment2recruiting
NCT01801670
Impact of Vorinostat on Pruritus Signaling Pathways - Merck StudyNo drug interventionsNot AvailableNot Availablewithdrawn
NCT03483870
Effect of Granisetron on Morphine Induced Pruritus in Cesarean Sectionprevention2completed
NCT05435170
Food Effect Study of Linerixibat Tablets in Healthy Adult Participantstreatment1completed
NCT03132142
Desensitization of Nociceptive Afferents by Application of Topical Capsaicin, Trans-cinnamaldehyde and L-mentholbasic_scienceNot Availableunknown_status
NCT06488742
The Efficacy of 3% Kanuka Oil Versus 1% Hydrocortisone Cream in Patients With Atopic DermatitisNo drug interventionstreatmentNot Availablerecruiting
NCT06435299
Efficacy and Tolerance of Cannabidiol in Patients With Severe Pruritus: a Multicenter, Double-blind, Randomized, Placebo-controlled Studysupportive_care3not_yet_recruiting
NCT00745199
Evaluating the Effect of Cromolyn Sodium in Uremic Pruritustreatment2completed
NCT05263206
Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)treatment3recruiting
NCT03617536
A Study to Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Severe Pruritustreatment2completed
NCT04399213
Dermal Blood Flow Response to Escalating Doses of Histamine, Administered by a Skin PrickNo drug interventionsbasic_scienceNot Availablecompleted
NCT03546816
Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Prurigo Nodularistreatment3completed
NCT05978063
Study to Evaluate the Efficacy and Safety of Oral Difelikefalin for Moderate to Severe Pruritus in Subjects With Notalgia Parestheticatreatment2 / 3terminated
NCT03343639
Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Plaque Psoriasistreatment2completed
NCT00884325
Management of Pruritus With Xyzal in Atopic Dermatitistreatment4completed
NCT04399525
Influence of H1-antihistamines on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin.basic_scienceNot Availablecompleted
NCT05133830
Linerixibat and Obeticholic Acid Drug Interaction Study in Healthy Adult Participantstreatment1completed
NCT02001948
Intrathecal Morphine for Inguinal Hernia Repair.treatment4completed
NCT04399148
Influence of Antipruritics on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin.basic_scienceNot Availablecompleted
NCT01092520
Gabapentin for the Treatment of Pruritus Caused by Burn Injuries in Childrentreatment1withdrawn
NCT05038982
Efficacy of Abrocitinib for Reducing Pruritus in Adults With Prurigo Nodularis and Chronic Pruritus of Unknown Origintreatment2completed
NCT01265082
Explore the Mechanisms of Pruritus in Bullous Pemphigoid Patients During RemissionNo drug interventionsNot AvailableNot Availableunknown_status
NCT02143973
Open Label Extension Study of Nalbuphine HCl ER in Hemodialysis Patients With Uremic Pruritustreatment2 / 3completed
NCT04337073
The Effect of Propofol on Dexamethasone-induced Perineal Pruritusprevention0completed
NCT04950127
Global Linerixibat Itch Study of Efficacy and Safety in Primary Biliary Cholangitis (PBC) (GLISTEN)treatment3active_not_recruiting
NCT04018027
Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Atopic Dermatitistreatment2completed
NCT04099927
A Study of SHR4010 in Patients With HemodialysisNo drug interventionstreatment1completed
NCT00715260
An Observational Study of Pruritus Amongst Hemodialysis PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT03540160
Study of the Long Term Safety of Serlopitant for the Treatment of Pruritus (Itch)treatment3terminated
NCT05500794
Meditation in Inflammatory DermatosisNo drug interventionsotherNot Availablerecruiting
NCT03816891
Study to Assess the Efficacy, Safety, and Tolerability of Vixarelimab in Reducing Pruritus in Prurigo Nodularistreatment2completed
NCT01586091
Safety Study of Levocetirizine and Fexofenadinetreatment4completed
NCT02671162
Evaluating the Effect of Fumaria Parviflora L. in Uremic PruritusNo drug interventionstreatment2completed
NCT00215280
Epidemiology and Control of Mansonella Perstans Infection in UgandatreatmentNot Availablecompleted
NCT04745429
Non-pharmacological Mitigation of PsoriasisNo drug interventionstreatmentNot Availablecompleted
NCT03290989
Itch and Pain Characteristics in Skin CarcinomasNo drug interventionsNot AvailableNot Availablecompleted
NCT04365244
Pruritus and Melanoma and Cutaneous Carcinomas Treated With ImmunotherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT01769144
Acticoat Absorbent and BCT Antimicrobial for STSG Donor Site on ThighNo drug interventionstreatmentNot Availableunknown_status
NCT03832140
Frequency and Characteristics of Pruritus in Patients With Monoclonal GammopathyNo drug interventionsNot AvailableNot Availablecompleted
NCT00568204
Study of Effectiveness of Mexyn-ANo drug interventionstreatmentNot Availablecompleted
NCT03458572
Acupuncture for Prevention of Itch in Caesarean SectionNo drug interventionspreventionNot Availablecompleted
NCT05180968
DIalysis Symptom COntrol-Pruritus Outcome Trialtreatment3completed
NCT05604469
The Role of Skin Microbiota in Hepatic or Renal PruritusNo drug interventionsNot AvailableNot Availablerecruiting
NCT04618146
Enhanced Recovery After Cesarean Section With Low Dose Intrathecal Morphine.preventionNot Availableunknown_status
NCT06226610
Dupixent in Adults With Refractory Post-Burn Pruritus in an Ambulatory Clinictreatment2not_yet_recruiting
NCT03448081
Safety, Tolerability and Efficacy of SNA-120 for Treatment of Pruritus and Psoriasis in Subjects Treated With Calcipotrienetreatment2completed
NCT06225323
Effect of Lidocaine Infusion on Neuraxial Opioid-induced Pruritus After Cesarean SectionpreventionNot Availablecompleted
NCT05342623
A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritustreatment3terminated
NCT02558738
Non Interventional Clinical Investigation of Ectoin Ear Spray in Skin Treatment of Outer Ear Canal IrritationsNo drug interventionsNot AvailableNot Availablecompleted
NCT02653703
L-menthol as a Topical Counter-irritant to TRPA1-induced Neurogenic Inflammation and PainNo drug interventionsbasic_scienceNot Availablecompleted
NCT00058903
Treatment of Cholestatic Pruritus With Sertralinetreatment2completed
NCT05135390
A Clinical Trial Evaluating the Efficacy and Safety of HSK21542 in Patients With Chronic Kidney Disease-Associated PruritusNo drug interventionstreatment3unknown_status
NCT00058890
Gabapentin to Treat Itch in Patients With Liver Diseasetreatment3completed
NCT02008864
Evaluating the Effect of Senna in Uremic PruritustreatmentNot Availablecompleted
NCT04325802
Treatment of Chronic Itch in Atopic Dermatitis With Opioid Antagonist Naltrexonetreatment2withdrawn
NCT06334679
The Effect of Cold Gel Pack Application on Itching in Burn Patients in the Maturation StageNo drug interventionssupportive_careNot Availablerecruiting
NCT01795079
Effects of Transcranial Direct Current Stimulation (tDCS) on Neuropathic Symptoms Following Burn InjuryNo drug interventionstreatmentNot Availablecompleted
NCT04154033
Treatment of Chronic Itch in Atopic Dermatitis With Topical Naltrexonetreatment2withdrawn
NCT00782054
Evaluation of Post Burn Rehabilitation Population for Itch ControlNo drug interventionstreatment4completed
NCT05634083
Does Indoxyl Sulfate Have a Role in Uremic Pruritus?No drug interventionstreatmentNot Availablecompleted
NCT06516783
Blue Light in the Treatment of Inflammatory Skin DiseasesNo drug interventionstreatmentNot Availablecompleted
NCT01897428
PK Comparisons of Bepotastine Besilate 10 mg and Bepotastine Salicylate 9.64 mgNot Available1completed
NCT01963793
Topical Aprepitant in Prurigo Patientstreatment2completed
NCT06120907
Swiss Itch RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT05387707
Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitistreatment3terminated
NCT04317209
A Study of SHR0410 in Hemodialysis Patients With PruritusNo drug interventionstreatment1unknown_status
NCT03322137
Safety, Efficacy, and Tolerability of SNA-120 in Subjects With Pruritus Associated With Psoriasis Vulgaristreatment2completed
NCT03796052
Study Determining Safety and Efficacy of Avena Sativa (Oat) Skincare Products for Treating Skin Dryness and Itching in Cancer PatientsNo drug interventionstreatmentNot Availablecompleted
NCT06290375
A Study of HSK21542 in a Peritoneal Dialysis Pruritus Population.No drug interventionstreatment2not_yet_recruiting
NCT05750875
Gabapentin Versus Loratadine in Uremic Pruritustreatment4completed
NCT04706975
Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica (KOMFORT)treatment2completed
NCT05448170
Linerixibat Compassionate Use for Cholestatic Pruritus Adult Patients With Primary Biliary Cholangitis (PBC)Not AvailableNot Availableavailable
NCT03035942
Quality of Recovery After Dexamethasone, Ondansetron or Placebo Intrathecal Morphine Administrationprevention4completed
NCT02975206
Study of the Efficacy, Safety, and Tolerability of Serlopitant for Pruritus (Itch) in Atopic Dermatitistreatment2completed
NCT01055236
Hydroxyzine for the Prevention of Pruritus From Spinal Morphine in Transabdominal Hysterectomy Patientsprevention4completed
NCT04518618
Effect of Intrathecal Naloxone in the Incidence of Pruritis After C.Ssupportive_careNot Availablecompleted
NCT00442819
Uremic Pruritus, Cytokines and Polymethylmethacrylate Artificial KidneyNo drug interventionstreatment4completed
NCT02174419
Study of Nalbuphine HCl ER Tablets in Patients With Prurigo Nodularistreatment2 / 3completed
NCT04415034
Scalp Pruritus Measurement Using Visual Analog Scale and 5-d Itch Scale in Children With Pediculosis CapitisNo drug interventionsNot AvailableNot Availablecompleted
NCT05287724
Defining N-Acetyl Cysteine as a Treatment for Inhibiting Prurogenic Stimulitreatment0completed
NCT03477058
In-Use Test With a Cosmetic Product to Treat PruritusNo drug interventionstreatmentNot Availablecompleted
NCT03824886
Enhancing SKIN Health and Safety in Aged CARENo drug interventionspreventionNot Availablecompleted
NCT02143648
Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritustreatment2 / 3completed
NCT02247648
Efficacy of Extended-release, Once Daily Tramadol for Post Operative Analgesia in Shoulder Arthroscopytreatment2terminated
NCT01071057
Naloxone for the Treatment of Opioid-Induced Pruritusprevention2 / 3completed
NCT03464526
A Study of the Efficacy and Safety of Orvepitant in Subjects With Pruritus Associated With Atopic Dermatitistreatment2withdrawn
NCT05870865
A Study to Evaluate the Anti-pruritic Effectiveness of ASN008 in Adults With Mild to Moderate Atopic DermatitisNo drug interventionstreatment2completed
NCT05525520
Study to Evaluate EP547 in Subjects With Cholestatic Pruritus Due to Primary Biliary Cholangitis or Primary Sclerosing CholangitisNo drug interventionstreatment2active_not_recruiting
NCT00257582
Study Of Cutaneous Disease Accompanied With Pruritus In Pediatricstreatment3completed
NCT03841331
Study of the Efficacy, Safety, and Tolerability of Serlopitant for the Treatment of Chronic Pruritus of Unknown Origintreatment2completed
NCT01905631
Blinded, Randomized Study Evaluating Aurstat Versus Control in the Treatment of Atopic Dermatitis Associated Pruritustreatment2completed
NCT04805073
Treatment of Pruritus With Intramuscular Promethazinetreatment4completed
NCT03209427
Serum Serotonin and Pruritus After Intrathecal Morphine in Cesarean Sectiondiagnostic4completed
NCT05393076
Phase I Study of Linerixibat in Adults With Moderate Hepatic Impairment and Healthy Controlstreatment1completed
NCT02650076
A Study to Investigate the Receptor Occupancy of SK-1405 in Healthy, Caucasian, Male SubjectsNo drug interventionstreatment1completed
NCT01727180
Pruritus in Patients With Chronic Kidney DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT03297580
Itch and Clinacal Caracteristics in Systemic SclerosisNo drug interventionsNot AvailableNot Availablecompleted
NCT04589429
Adding Nalbuphine for Control of Intrathecal Morphine Pruritusprevention2unknown_status
NCT02229929
Safety and Pharmacokinetics of IV CR845 in Hemodialysis Patients, and Its Efficacy in Patients With Uremic Pruritustreatment2completed
NCT03096444
Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocainetreatment2terminated
NCT01919944
Study of Itch Control by VLY-686 in Healthy Volunteers After Intradermal Injections of Substance Pprevention1completed
NCT00577967
Gabapentin - A Solution to Uremic Pruritus?treatmentNot Availableunknown_status
NCT05936567
Study Evaluating the Efficacy and Safety of Povorcitinib in Adults With Chronic Spontaneous Urticariatreatment2recruiting
NCT02823067
Pruritus and Pemphigoid in Nursing Home PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT03677401
Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Prurigo Nodularistreatment3completed
NCT03317301
Evaluate the Efficacy and Safety of HL151 Versus Talion Tab. in Pruritus Cutaneustreatment3completed
NCT01114672
A Study of Oral Ergocalciferol to Treat Pruritis in Hemodialysis Patientstreatment4completed
NCT03857568
A Trial of SHR0410 Injection in Hemodialysis Participants.No drug interventionstreatment1completed
NCT02909569
Relieving Chronic Itch: Oral Medicationtreatment2withdrawn
NCT02769910
Effects of High-concentration Topical Capsaicin on Histaminergic and Non-histaminergic Itchtreatment1 / 2completed
NCT02846181
A Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-SK-1405No drug interventionsbasic_science1completed
NCT03340155
Mechanisms of Action of Photo(Chemo)Therapy in Skin DiseasesNo drug interventionsotherNot Availableunknown_status
NCT01825655
Study of Using Long Acting Antihistamine to Treat Opioid Induced Itchingtreatment4terminated
NCT01625455
Effect of Neurokinin-1 Receptor (NK1R) Antagonism on Pruritus in Patients With Sezary Syndrometreatment4terminated
NCT05779150
Efficacy of CeraVe® Moisturizing Cream on Skin Pruritus in Elderly PatientsNo drug interventionstreatmentNot Availablerecruiting
NCT05659823
Postoperative Pain After Caesarian Sectiontreatment4completed
NCT01605708
Study to Assess the Clinical Activity of a Sequential Dose of REGN846 on Refractory Pruritus in Patients With Atopic DermatitisNo drug interventionstreatment1 / 2terminated
NCT02432508
Efficacy of Laser Acupuncture on Pruritus in Patients With Chronic Kidney Disease Undergoing HemodialysisNo drug interventionstreatmentNot Availableunknown_status
NCT03262038
Does IV Ondansetron Prevent Pruritus After Intrathecal Morphine in Pediatric Patients?prevention4terminated
NCT04326738
The Effect of Midazolam on Dexamethasone-induced Perineal Pruritusprevention0completed
NCT02793843
Ondansetron vs Ondansetron Plus Dexamethasone for Relieving Intrathecal Morphine Side Effects After C-sectionpreventionNot Availablecompleted
NCT01702103
Demonstrate the Therapeutic Clinical Equivalence of Two Mometasone Nasal SpraysNot Available3unknown_status
NCT00137202
Post Burn Pruritus Study in Patients Undergoing Wound HealingtreatmentNot Availablecompleted
NCT04962152
Naldebain and Video-assisted Thoracoscopic SurgeryNo drug interventionstreatment4recruiting
NCT06104540
Comparison of the Effects of Liquid Vaseline and Olive Oil on Itching and Scarring in Scald BurnsNo drug interventionspreventionNot Availablerecruiting
NCT06479967
The Effects of Virtual Reality and Music on Pain, Anxiety, Itching, and Vital SignsNo drug interventionsotherNot Availablecompleted
NCT06323304
Efficacy and Safety of Auricular Acupressure in Treating Allergic RhinitisNo drug interventionstreatmentNot Availablerecruiting
NCT01693198
Cyanobacteria Allergy in Lake KineretNo drug interventionsdiagnosticNot Availableunknown_status
NCT02951806
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