manic syndromes (DBCOND0023146)

Identifiers

Synonyms

Manic State / Manic episode, unspecified / Mania / Mania (disorder)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Benperidol	A neuroleptic butyrophenone derivative indicated in the treatment of psychoses, manic episodes, and psychomotor agitation.	No drug targets
Thioproperazine	An antipsychotic indicated for the management of acute and chronic schizophrenia, including cases that are refractory to more common neuroleptics. May also be used to treat manic syndromes.	D(2) dopamine receptortarget D(1A) dopamine receptortarget Alpha-1A adrenergic receptortarget Alpha-1B adrenergic receptortarget Albumincarrier

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT00431184	Effects of Pentazocine Versus Lorazepam on Manic Symptoms	Lorazepam Naloxone Pentazocine	treatment	2	completed
NCT00521365	Effectiveness of Quetiapine XR on the Control of Symptoms of Manic Phase of Bipolar Disorder.	Quetiapine	treatment	4	completed
NCT00422123	Phase 3 /Seroquel SR Acute Mania Monotherapy - US	Quetiapine	treatment	3	completed