Alpha-1B adrenergic receptor

BE0000575ProteinHumansADRA1B

Alpha-1 adrenergic receptors are G protein-coupled receptors for catecholamines that signal through the G(q) family of G proteins, including G(q) and G(11). It is acted on by 71 drugs in DrugBank.

Gene name
ADRA1B
UniProtKB entry
P35368Swiss-Prot
Cellular location
Nucleus membrane
Residues / weight
520 residues · 56,835 Da
Also known as
Alpha-1B adrenoceptor · Alpha-1B adrenoreceptor

Resolves to

Protein
UniProtP35368UniProt nameADA1B_HUMAN
Gene
HGNCHGNC:278NCBI Gene147GeneCardsADRA1B
Pharmacology
IUPHAR/GtoPdb23KEGGhsa:147
Drugs

What you can answer from here — as of September 07, 2019

71DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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166+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Alpha-1B adrenergic receptor, how selective are they, and which programs against it are still in active trials?

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