Refractory Leukemia (DBCOND0043073)

Identifiers

Synonyms
Not Available

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Amsacrine
A cytotoxic agent used to induce remission in acute adult leukemia that is not adequately responsive to other agents.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT04874480
Tegavivint for the Treatment of Relapsed or Refractory Leukemiatreatment1active_not_recruiting
NCT06644183
A Phase 1/2, Open Label, Study of Roginolisib (IOA-244), an Orally Bioavailable, Selective PI3Kδ Inhibitor in Patients With Refractory/Relapsed Chronic Lymphocytic Leukemia (CLL) in Combination With Venetoclax and RituximabNo drug interventionstreatment1 / 2not_yet_recruiting
NCT05305859
Venetoclax Combining Chidamide and Azacitidine (VCA) in the Treatment of R/R AMLtreatment2recruiting
NCT06006403
Safety and Efficacy of CD123-targeted CAR-NK for Relapsed/Refractory Acute Myeloid Leukemia or Blastic Plasmacytoid Dendritic Cell Neoplasmtreatment1 / 2recruiting
NCT05043571
CARTALL: Chimeric-Antigen Receptor (CAR) T-Cell Therapy for Relapsed/ Refractory T-Lineage Acute Lymphoblastic LeukaemiaNo drug interventionstreatment1recruiting
NCT05576532
Venetoclax Plus IM2 Regimen for Relapsed and Refractory T Lymphoblastic Lymphoma/LeukemiaNo drug interventionstreatment2recruiting
NCT05164042
Allogeneic CD19 CAR-T Cells for the Treatment of Relapsed/Refractory B-cell Acute Lymphoblastic LeukemiaNo drug interventionstreatment1 / 2unknown_status
NCT03799224
Decitabine Plus mBU/CY Preconditioning for Relapse/Refractory Acute Leukemiatreatment2 / 3unknown_status
NCT05046444
Solving Riddles Through SequencingNo drug interventionsNot AvailableNot Availablerecruiting
NCT05321940
Safety Trial of STING-dependent Activators and Stimulated Dendritic Cells for Aggressive Relapsed/Refractory LeukemiasNo drug interventionstreatment1withdrawn
NCT00880269
Efficacy and Safety of Panobinostat (LBH589) in Patients With Refractory de Novo or Secondary Acute Myelogenous Leukemia (AML)treatment2completed
NCT05519384
Safety and Preliminary Efficacy of JK500 Cell Injection in Relapsed/Refractory Pediatric Acute Myeloid Leukemiatreatment0recruiting
NCT04470947
Comprehensive Genomic Profiling and Next Generation Functional Drug Screening for Patients With Aggressive Haematological MalignanciesNo drug interventionsNot AvailableNot Availablerecruiting
NCT04282811
Observational Study Relapsed or Refractory Chronic Lymphocytic Leukemia Venetoclax-based Regimens Outside Clinical Trials in ItalyNot AvailableNot Availablerecruiting
NCT04722952
PD-1 Inhibitor Combined With Azacytidine and Homoharringtonine,Cytarabine, G-CSF for Refractory or Relapsed AMLtreatment3unknown_status
NCT05495035
Study for Safety and Efficacy of Olverembatinib Combined With APG-2575 in Children With Relapsed/Refractory Ph + ALLtreatment1recruiting
NCT04597086
Bright White Light Therapy for the Improvement of Sleep, Fatigue, Distress, Depression, and Anxiety in Hospitalized Leukemia PatientsNo drug interventionssupportive_careNot Availablecompleted
NCT02512926
Carfilzomib in Combination With Cyclophosphamide and Etoposide for Childrentreatment1completed
NCT04684472
Modified CD19 CAR-T in Patients With Relapsed or Refractory CD19+ B-cell MalignanciesNo drug interventionstreatment1unknown_status
NCT05870995
Chemotherapy CLAGE-Ven Sequential With Reduced Intensity Conditioning for Refractory Acute Myelodi LeukemiaNo drug interventionstreatment2recruiting