Critical Limb Ischemia (CLI) (DBCOND0044892)

Identifiers

Synonyms
Critical Ischemia Limb / Limb Ischemia, Critical / Critical Limb Ischaemia / Critical Limb Ischemia / Chronic Limb-Threatening Ischemia / Chronic limb-threatening ischaemia / Chronic limb ischemia / Chronic limb ischaemia / Peripheral obliterative arteriopathy / Peripheral arterial occlusive disease / Peripheral arterial occlusive disease (disorder)

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05643378
Role and Outcome of Endovascular Revascularization of Chronic Limb IschaemiaNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05830721
Continuous Compartment Pressure Monitoring for Compartment Syndrome in VA-ECMO PatientsNo drug interventionsdiagnosticNot Availablerecruiting
NCT06238050
NOrmoBaric Oxygen Therapy Use In Critical Limb ISchemiaNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01942941
Peripheral Vascular Disease and Nerve StimulationNo drug interventionstreatmentNot Availablecompleted
NCT02634138
Neuromuscular Electrical Stimulation in Patients With Critical Limb IschaemiaNo drug interventionstreatmentNot Availableterminated
NCT05208905
LIFE-BTK PK Sub-studyNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT02538978
Critical Limb Ischemia Rapid Delivery by SurgWerks-CLI Kit and VXP SystemNo drug interventionstreatment3unknown_status
NCT03746899
Expanded Access for Treatment Use of PLX-PAD in Critical Limb Ischemia (CLI)Not AvailableNot Availableavailable
NCT03886506
Expanded Access Treatment of Subjects With Critical Limb Ischemia (CLI) With Minor Tissue Loss Who Are Unsuitable for RevascularizationNot AvailableNot Availableavailable
NCT01386216
Safety Study of Bone Marrow Cell Concentrate Prepared Using the Magellan System to Treat Critical Limb Ischemia (CLI)No drug interventionstreatment1completed
NCT03174522
The Efficacy and Safety of REX-001 to Treat Ischemic Ulcers in Subjects With CLI Rutherford Category 5 and DMNo drug interventionstreatment3terminated
NCT03111238
The Efficacy and Safety of REX-001 to Treat Ischemic Rest Pain in Subjects With CLI Rutherford Category 4 and DMNo drug interventionstreatment3terminated
NCT03006770
Efficacy, Tolerability and Safety of Intramuscular Injections of PLX PAD for the Treatment of Subjects With Critical Limb Ischemia (CLI) With Minor Tissue Loss Who Are Unsuitable for Revascularizationtreatment3completed
NCT04227899
LIFE-BTK Randomized Controlled TrialNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00987363
Intraarterial Infusion of Autologous Bone Marrow in Diabetic Patients With Chronic Ischemia of Lower Limbs (CLI) no RevascularizationNo drug interventionstreatment1 / 2completed
NCT04849325
IBS Titan vs. PTA in Patients With Infrapopliteal Arterial Stenosis or Occlusive DiseaseNo drug interventionstreatmentNot Availablerecruiting
NCT02287974
Clinical Trial I/II Opened, Randomized and Controlled for the Study of the Use of Stem Cells Therapy in Insulinized Diabetic Patients Type 2 With Critical Ischemia in Lower Limbs (CLI): Study of the Needs of InsulinNo drug interventionstreatment1 / 2terminated
NCT01257776
Human Adipose Derived Mesenchymal Stem Cells for Critical Limb Ischemia (CLI) in Diabetic PatientsNo drug interventionstreatment1 / 2completed
NCT01408381
Intra-arterial Infusion of Autologous Bone Marrow Mononuclear Cells in Non-diabetic Patients With Critical Limb Ischemia (CLI).No drug interventionstreatment2completed
NCT01644487
Self-Expanding Nitinol Stent Versus Balloon Angioplasty Alone for the Below The Knee Arteries(SENS-BTK)No drug interventionstreatmentNot Availablecompleted
NCT03214887
Autologous BMMNC Combined With HA Therapy for PAODNo drug interventionstreatment1 / 2withdrawn
NCT05455554
The Use of FlowMet-R Technology to Predict Wound Healing in CLI Patients in a Wound Care Center SettingNo drug interventionsNot AvailableNot Availableunknown_status
NCT02829151
Comparison of Cilostazol-based Triple Antiplatelet Therapy Versus Dual Antiplatelet Therapy for Outcomes of below-the Knee Endovascular Intervention in Patients With Critical Limb Ischemia (TAP CLI Study)treatment4unknown_status
NCT03668353
Recombinant SeV-hFGF2/dF Injection for PAODNo drug interventionstreatment1unknown_status
NCT00764777
Efficacy Study of Iliac Stents to Treat TASC A-B-C-D Iliac Artery LesionsNo drug interventionstreatment4completed
NCT02145845
Pilot Safety Study of Injectable SIS for Critical Limb IschemiaNo drug interventionstreatmentNot Availablecompleted
NCT01483898
An Efficacy and Safety Study of Ixmyelocel-T in Patients With Critical Limb Ischemia (CLI)treatment3completed
NCT04209998
New Oxymetry Indices in Critical Limb IschemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT03680105
A Safety and Tolerability Study of RJX Drug Product in Healthy ParticipantsNo drug interventionsbasic_science1completed
NCT02145897
To Evaluate the Safety and Efficacy of IM and IV Administration of Autologous ADMSCs for Treatment of CLINo drug interventionstreatment1 / 2unknown_status
NCT03253328
N-Acetyl-Cysteine (NAC) for Healing of Amputation Stumps in the Setting of Diabetestreatment0completed
NCT04306471
Effect of Evolocumab in Patients With Critical Limb Ischemia (Evol-CLI)treatment4unknown_status
NCT00459888
Cryoplasty CLIMB-registryNo drug interventionstreatment4completed
NCT04054609
FAZA PET/MRI in CLI Patients Pre and Post RevascularizationNo drug interventionsdiagnosticNot Availableunknown_status
NCT01833585
Treatment of Chronic Critical Limb Ischemia With G-CSF-mobilized Autologous Peripheral Blood Mononuclear CellsNo drug interventionstreatment3completed
NCT00651885
Safety Study of UT-15C SR (Oral Treprostinil) in Patients Undergoing a Lower Limb Endovascular Proceduretreatment2completed
NCT01638585
Safety and Efficacy Study of Urokinase for the Treatment of Diabetic Foot Syndrome and Critical Limb Ischemiatreatment3terminated
NCT05854615
Efficacy and Safety of Stempeucel® in Patients With Critical Limb Ischemia (CLI) Due to Buerger's Diseasetreatment4recruiting
NCT06204237
Safety, Tolerability, and Biodistribution of [89Zr]Zr-DFO-APAC in Subjects with PAOD/CLI and Healthy Volunteers (Acronyms: 89Zr = Zirconium-89, DFO = Desferrioxamine, APAC = AntiPlatelet AntiCoagulant, PET/CT = Positron Emission Tomography/Computed Tomography)No drug interventionsother0recruiting
NCT06191237
Effect of Environmental Temperature on Vascular Ultrasound Vein Scan MeasurementsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03423732
Cardiovascular Clinical Project to Evaluate the Regenerative Capacity of CardioCell in Patients With No-option Critical Limb Ischemia (N-O CLI)No drug interventionstreatment2 / 3unknown_status
NCT02802852
Proteomics and Stem Cell Therapy as a New Vascularization StrategytreatmentNot Availablecompleted
NCT01877252
Registry of First-line Treatments in Patients With Critical Limb IschemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT02475200
Phoenix Post-Approval Registry - Using the Phoenix Atherectomy SystemsNo drug interventionsNot AvailableNot Availablecompleted
NCT00913900
Safety Study of Adult Stem Cells to Treat Patients With Severe Leg Artery DiseaseNo drug interventionstreatment1terminated
NCT03171259
SCOPE CLI (Shifting Care and Outcomes for Patients With Endangered Limbs - Critical Limb Ischemia)No drug interventionsNot AvailableNot Availablecompleted
NCT03041259
Revascularization of Stenosed Vessels Using Optimized Treatment of Rejuveinix for Reversing Endothelial DysfunctionNo drug interventionstreatment1 / 2unknown_status
NCT03094559
Correlation Between FlowMet™ and Other Gold Standard Assessments in the Management of Critical Limb Ischemia (CLI)No drug interventionsdiagnosticNot Availablewithdrawn
NCT02235675
Tack Optimized Balloon Angioplasty Below the Knee (TOBA - BTK) StudyNo drug interventionstreatmentNot Availablecompleted
NCT00869375
Use of Clearway™ Balloon vs. Mechanical Thrombectomy as Initial Treatment for Acute Limb IschemiaNo drug interventionstreatmentNot Availableterminated
NCT04365075
Excimer Laser Combined With DCB Compared With Angioplasty Alone in the Treatment of Infrapopliteal Lesions.No drug interventionstreatmentNot Availablerecruiting
NCT02212470
Drug Eluting Balloon Angioplasty Versus Nitinol Stent Implantation in the Superficial Femoral ArteryNo drug interventionstreatment4completed
NCT04746599
Autologous Fat Grafting in the Treatment of Critical Limb IschaemiaNo drug interventionstreatmentNot Availableunknown_status
NCT00721006
Phase II Combination Stem Cell Therapy for the Treatment of Severe Leg IschemiaNo drug interventionstreatment2completed
NCT02963649
IN.PACT BTK Randomized Study to Assess Safety and Efficacy of IN.PACT 014 vs. PTANo drug interventionstreatmentNot Availablecompleted
NCT04162418
A Study of the TEmporary Spur StEnt System for the Treatment of Lesions Located in the InfraPoplitEal ARteries Using a LIMUS-base DCBNo drug interventionstreatmentNot Availablecompleted
NCT02501018
Study to Assess the Efficacy and Safety of CLBS12 in Patients With Critical Limb Ischemia (CLI)treatment2completed
NCT05570019
Evaluation of Tissue Perfusion in Peripheral Arterial Disease (EVTI-PAD)No drug interventionsNot AvailableNot Availablerecruiting
NCT01049919
Safety and Efficacy Study of Autologous Concentrated Bone Marrow Aspirate (cBMA) for Critical Limb Ischemia (CLI)No drug interventionstreatmentNot Availableterminated
NCT05854641
Efficacy and Safety of Stempeucel® in Patients With Critical Limb Ischemia (CLI) Due to Peripheral Arterial DiseaseNo drug interventionstreatment4recruiting
NCT01459341
Near Infrared Spectroscopy and Transcutaneous Oxygen Pressure in Critical Limb Ischemia Before and After TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT00637741
DURABILITY-200: EverFlex 200mm Long Nitinol Stents in TASC C&D Femoropopliteal LesionsNo drug interventionstreatment4completed
NCT00696124
Safety Study of Gene Therapy in Treating Lower Leg Ischemiatreatment1completed
NCT03551496
The DES BTK Vascular Stent System vs PTA in Subjects With Critical Limb IschemiaNo drug interventionstreatment3completed
NCT03669458
Feasibility Clinical Trial Using the SPUR System to Demonstrate Safety and Efficacy.No drug interventionsdevice_feasibilityNot Availablecompleted
NCT00919958
Safety of Intramuscular Injection of Allogeneic PLX-PAD Cells for the Treatment of Critical Limb Ischemiatreatment1completed
NCT03239535
Allogeneic Mesenchymal Stem Cells for the Critical Limb Ischemia TherapyNo drug interventionstreatment1 / 2unknown_status
NCT03455335
Autologous Stem Cells for the Treatment of No Option Critical Limb IschemiaNo drug interventionstreatment1completed
NCT01245335
Bone Marrow Aspirate Concentrate (BMAC) for Treatment of Critical Limb Ischemia (CLI)No drug interventionstreatment3completed
NCT03909022
Assessing Best Medical Treatment Patterns of Patients With Symptomatic Peripheral Arterial Occlusive Disease in GermanyNo drug interventionsNot AvailableNot Availableunknown_status
NCT02260622
Pilot Study to Examine the Use of Rivaroxaban After Angioplasty for Critical Limb Ischemiaprevention2completed
NCT02060630
Best Endovascular vs. Best Surgical Therapy in Patients With Critical Limb IschemiaNo drug interventionstreatmentNot Availablecompleted
NCT02790957
Plerixafor in Diabetic Wound Healingtreatment2terminated
NCT00760357
A Retrospective Analysis of Patients With Full Thickness Wounds in Limbs With Critical IschemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT04058626
TEsting for Arterial Disease in Diabetes (TrEAD) StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT05313165
PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening IschemiaNo drug interventionstreatmentNot Availablerecruiting
NCT01758874
Study to Explore the Effect of Lowering Blood Viscosity in Patients With Treatment-resistant Critical Limb IschemiaNo drug interventionstreatment2completed
NCT03455374
Diamondback in Peripheral Vascular DiseaseNo drug interventionstreatmentNot Availableterminated
NCT04452682
The Impact of COVID-19 Pandemic on Critical Limb Threatening Ischemia and Emergency Vascular PracticeNo drug interventionsNot AvailableNot Availablecompleted
NCT04071782
Investigating the Safety and Efficacy of the Treatment With the Selution Sirolimus Coated Balloon in TASC C and D Tibial Occlusive Disease in Patients With Critical Limb Ischemia From SingaporeNo drug interventionstreatmentNot Availablecompleted
NCT02454231
Monocentric Trial: Stem Cell Emergency Life Threatening Limbs Arteriopathy (SCELTA)treatment2 / 3completed
NCT01410331
Study to Evaluate the Safety and Efficacy of JVS-100 Administered to Adults With Critical Limb IschemiaNo drug interventionstreatment2completed
NCT04110327
An All-Comers Observational Study of the MicroStent™ Peripheral Vascular Stent System in Subjects With Peripheral Arterial DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT01595776
Autologous Endothelial Progenitor Cells (EPCs) From Peripheral Blood in the Treatment of Critical Limb IschemiaNo drug interventionstreatment1 / 2completed
NCT06434194
Serrantor OCT StudyNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00616980
Injection of Autologous CD34-Positive Cells for Critical Limb IschemiaNo drug interventionstreatment1 / 2completed
NCT02106429
Platelet Activity in Vascular Surgery and Cardiovascular EventsNo drug interventionsNot AvailableNot Availablecompleted
NCT04165629
Platelet Reactivity in PAD Undergoing Percutaneous AngioplastyNot AvailableNot Availableunknown_status
NCT00922389
A Clinical Trial on Diabetic Foot Using Peripheral Blood Derived Stem Cells for Treating Critical Limb Ischemiatreatment1 / 2unknown_status
NCT03293589
Open Versus Endovascular Revascularization in Patients With End-stage Renal DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT04661644
Efficacy and Safety of Mesenchymal Stem Cell Clusters in Patients with Critical Limb IschemiaNo drug interventionstreatment1 / 2completed
NCT03175744
Stellarex DCB Versus Standard Balloon Angioplasty for Treatment of Below-The-Knee (BTK) ArteriesNo drug interventionstreatmentNot Availablesuspended
NCT02477540
A Safety and Efficacy Study of Autologous Bone Marrow Derived Mesenchymal Stem Cells in Critical Limb IschemiaNo drug interventionstreatment1withdrawn
NCT01064440
Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemiatreatment2completed
NCT01341340
The ABSORB BTK (Below The Knee) Clinical InvestigationNo drug interventionstreatmentNot Availableterminated
NCT01273740
Swedish External Support StudyNo drug interventionstreatmentNot Availablecompleted
NCT04255004
Autologous Peripheral Blood Mononuclear Cells in Diabetic Foot Patients With No-option Critical Limb IschemiaNo drug interventionstreatmentNot Availablecompleted
NCT04433572
Temsirolimus Adventitial Delivery to Improve ANGioplasty and/or Atherectomy Revascularization Outcomes Below the Kneetreatment3not_yet_recruiting
NCT01938872
Evaluating the Effectiveness of Paclitaxel-eluting Balloons for Below-the-knee Angioplasty in Patients With Critical Limb IschemiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT06066268
miRNAs in Critical Limb Ischemia (miRNACLI)No drug interventionsNot AvailableNot Availablerecruiting
NCT06359912
Safety and Preliminary Efficacy of Allogeneic Endothelial Progenitor Cells (EPCs) in Patients With Critical Limb IschemiaNo drug interventionstreatment1recruiting
NCT01351610
Tolerability and Efficacy of Intravenous Infusion of Autologous MSC_Apceth for the Treatment of Critical Limb IschemiaNo drug interventionstreatment1 / 2completed
NCT00951210
Safety of Intramuscular Injections (IM) of Allogeneic PLX-PAD Cells for the Treatment of Critical Limb Ischemia (CLI)treatment1completed
NCT02144610
Efficacy and Safety of AMG0001 in Subjects With Critical Limb Ischemiatreatment3terminated
NCT04369781
Critical Limb Ischemia and Transcutaneous OximetryNo drug interventionsNot AvailableNot Availableunknown_status
NCT02043795
Drug Impregnated Bioabsorbable Stent in Asian Population Extremity Arterial Revascularization (DISAPEAR Study)No drug interventionsotherNot Availablecompleted
NCT01446055
Safety and Efficacy Study of Autologous BM-MNC Processed by Two Methods for Treating Patients With Chronic Limb IschemiaNo drug interventionstreatment1 / 2unknown_status
NCT02016755
A Phase IIB Pilot Study of a Modified Dosage Regimen of AMG0001 in Subjects With Critical Limb IschemiaNo drug interventionstreatment2completed
NCT02094755
Aspirin and Clopidogrel Reactivity in Patients With Critical Limb Ischemia (CLI)No drug interventionsNot AvailableNot Availablecompleted
NCT02389023
Comparison of Prevena Negative Pressure Incision Management System vs. Standard Dressing After Vascular SurgeryNo drug interventionspreventionNot Availableunknown_status
NCT01579123
Laser Atherectomy Versus Angioplasty for the Treatment of Critical Limb IschemiaNo drug interventionstreatmentNot Availablecompleted
NCT06367803
Cost Analysis of Vascular Surgical TechniquesNo drug interventionsNot AvailableNot Availablecompleted
NCT04229264
Efficacy and Safety of Apixaban in Reducing Restenosis and Limb Loss in PAD Patients.treatment3unknown_status
NCT01609621
Tibiopedal Access for Crossing of Infrainguinal Artery OcclusionsNo drug interventionsNot AvailableNot Availablecompleted
NCT05456802
Effect of Acute Cardiovascular Disease on MicrobiomeNo drug interventionsNot AvailableNot Availablerecruiting
NCT02807779
Intima Versus Adventitia Drug Delivery to Elucidate Mechanisms of Restenosis: Magnetic Resonance Imagingbasic_science4unknown_status
NCT02974179
A Long Term Follow-up Study of AMG0001 in Subjects With Critical Limb IschemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT01297387
Feasibility of Peripheral Angioplasty in Type D TASCII LesionsNo drug interventionsNot AvailableNot Availablecompleted
NCT02864654
Effectiveness and Safety of Adipose-Derived Regenerative Cells for the Treatment of Critical Lower Limb IschemiaNo drug interventionstreatment1 / 2unknown_status
NCT04312451
Prospective Cohort of Patients With Critical Limb Ischemia Undergoing RevascularizationNo drug interventionsNot AvailableNot Availablerecruiting
NCT05358353
A Prospective Single-Arm Multicenter StuDy of the BarE TEmporary SPur StEnt System foR the tREatment of Vascular Lesions Located in the infrapoplitEal Arteries beLow the Knee (DEEPER REVEAL)No drug interventionstreatmentNot Availablerecruiting
NCT03839953
Exercise Rehabilitation for Patients With Critical Limb Ischemia After RevascularizationNo drug interventionstreatmentNot Availableunknown_status
NCT04304105
Natural Progression of High-Risk Chronic Limb-Threatening Ischemia: The CLariTI StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT04974905
Retrograde Recanalization of Infrainguinal Arterial Occlusive Disease.No drug interventionstreatmentNot Availableunknown_status
NCT01558505
Drug Eluting Balloon in peripherAl inTErvention For Below The Knee Angioplasty EvaluationNo drug interventionstreatment4completed
NCT06186505
Heat Therapy for Peripheral Arterial Disease (HEATPAD)No drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04175197
LegDeb2 Global Registry for Use of Legflow in Peripheral ArteriesNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06174597
Umbilical Cord Artery-derived Perivascular Stem Cells for the Critical Limb Ischemia TherapyNo drug interventionstreatment0recruiting
NCT03987061
MOTIV Bioresorbable Scaffold in BTK Artery DiseaseNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT03807661
Percutaneous Deep Vein Arterialization Post-Market StudyNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT03686228
Treatment of No-option CLI by G-CSF-mobilized PB-MNCNo drug interventionstreatmentNot Availableunknown_status
NCT01311011
Study of the Clinical Efficacy of Autologous SCT in Patients With Critical Limb IschemiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT01799811
Cryopreserved Saphenous Vein Allograft in Patients With Critical Limb Ischemia for Peripheral RevascularizationNo drug interventionsNot AvailableNot Availablecompleted
NCT03982693
Trial to Assess Chelation Therapy in Critical Limb Ischemiatreatment3recruiting
NCT00510393
Drug Eluting Stents In The Critically Ischemic Lower LegNo drug interventionstreatment2completed
NCT05145478
CRUSH PAD: Real-world Outcomes Following Use of the Shockwave Intravascular Lithotripsy (IVL) Technology in Calcified Common Femoral LesionsNo drug interventionsNot AvailableNot Availablerecruiting
NCT02234778
Evaluation of the Tissue Genesis® Icellator Cell Isolation System™ to Treat Critical Limb IschemiaNo drug interventionstreatmentNot Availableunknown_status
NCT04043078
Exercise In Critical Limb Ischaemia Patients Having Surgery Proof of ConceptNo drug interventionsotherNot Availablecompleted
NCT05575778
Peri-operative Foot CT Perfusion in CLI PatientsNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02051088
Swedish Drug-elution Trial in Peripheral Arterial DiseaseNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00392509
ALD-301 for Critical Limb Ischemia, Randomized TrialNo drug interventionstreatment1 / 2completed
NCT00304837
VEGF Gene Transfer for Critical Limb IschemiaNo drug interventionsNot Available1completed
NCT00956332
Safety Study of MultiGeneAngio in Patients With Chronic Critical Limb IschemiaNo drug interventionstreatment1 / 2active_not_recruiting
NCT03321552
PROMISE InternationalNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT02099500
Autologous Adipose-Derived Stromal Cell Delivered Via Intramuscular Injections for the Treatment of Critical Limb IschemiaNo drug interventionstreatment1withdrawn
NCT00445159
UT-15C SR in the Treatment of Critical Limb Ischemiasupportive_care2unknown_status
NCT03124875
PROMISE I Early Feasibility Trial of the LimFlow Stent Graft SystemNo drug interventionstreatmentNot Availablecompleted
NCT00883870
Mesenchymal Stem Cells in Critical Limb IschemiaNo drug interventionstreatment1 / 2completed
NCT01599442
Register for Patients With Diabetic Foot Syndrome and Critical Limb IschemiaNo drug interventionsNot AvailableNot Availableterminated
NCT05018949
Evaluation of Post-Angioplasty OutcomesNo drug interventionsNot AvailableNot Availableunknown_status
NCT04583436
Efficacy and Safety Comparison of the Open and Endovascular Surgical Methods for the Treatment of Long Atherosclerotic Lesions of the Femoral-popliteal Segment Below the Knee, TASC D in Patients With Critical Limb IschemiaNo drug interventionstreatmentNot Availablerecruiting
NCT02239419
Evaluation of Carbothera in the Treatment of Foot UlcersNo drug interventionspreventionNot Availableunknown_status
NCT01676519
Impact of Critical Limb Ischemia on Long Term Cardiac Mortality in Diabetic Patients Undergoing Percutaneous Coronary RevascularizationNo drug interventionsNot AvailableNot Availablecompleted
NCT03529019
Nutrition in Patient With Critical Limb IschemiaNo drug interventionssupportive_care0recruiting
NCT02941419
Treatment of PAD by Platelet Lysate for Therapeutic Angiogenesistreatment1 / 2completed
NCT01456819
Intramuscular Mononuclear Cells and Mesenchymal Stem Cells Transplantation to Treat Chronic Critical Limb IschemiaNo drug interventionstreatment2unknown_status
NCT04760119
Drug-Eluting Balloon Angioplasty Versus Bypass Surgery as First-Line Strategies in Infrageniculate Arterial Disease for Critical Limb Ischemia in Type 2 Diabetic Pacients: a Randomised Controlled Clinical TrialNo drug interventionstreatmentNot Availableunknown_status
NCT04427124
The CLI-AMP RegistryNo drug interventionsNot AvailableNot Availableunknown_status
NCT02054416
External Compression Therapy for Secondary Prevention of Lower-Limb Loss and Cardiovascular MortalityNo drug interventionstreatmentNot Availableunknown_status
NCT00060996
Study of Remodulin in Patients With Critical Limb Ischemia With No Planned Revascularization Procedurestreatment3terminated
NCT06544135
Use of Thermal Imaging Camera to Assess Perfusion Before and After Vascular InterventionNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03693963
The PRELUDE BTK StudyNo drug interventionstreatmentNot Availablecompleted
NCT01285986
Scandinavian Miller Collar StudyNo drug interventionstreatmentNot Availablecompleted
NCT01584986
Autologous Angiogenic Cell Precursors (ACPs) for the Treatment of Peripheral Artery DiseaseNo drug interventionstreatment2completed
NCT05161039
Serranator Recoil StudyNo drug interventionstreatmentNot Availableunknown_status
NCT05406622
MOTIV BTK Randomized Controlled TrialNo drug interventionstreatmentNot Availablerecruiting
NCT01211925
Distal Venous Arterialisation of Ischemic Limbtreatment2 / 3unknown_status
NCT02601430
BOLD MRI as a Surrogate of Improved Muscle Oxygenation Following Endovascular Therapy for the Treatment of CLINo drug interventionsotherNot Availablecompleted
NCT01941030
Complete Lesion Assessment With ffR and IVUS TechnologYNo drug interventionstreatmentNot Availablecompleted
NCT02863926
Use of Autologous Concentrated Bone Marrow Aspirate in Preventing Wound Complications in Below Knee Amputation (BKA)No drug interventionstreatment1completed
NCT02046226
Dissolved Oxygen Dressing to Improve Chronic Wound Healing After Revascularization for Critical Limb IschemiaNo drug interventionstreatmentNot Availableterminated
NCT03994666
Cell Therapy in Critical Limb Ischemiatreatment2unknown_status
NCT01216865
Umbilical Cord Mesenchymal Stem Cells Injection for Diabetic FootNo drug interventionstreatment1 / 2unknown_status
NCT04748965
Imaging-Guided Vessel Sizing in the Tibial ArteriesNo drug interventionsNot AvailableNot Availablecompleted
NCT06122974
Drug Eluting Temporary Spur Stent System vs Percutaneous Balloon Angioplasty for the Treatment of Critical Limb IschemiaNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT01484574
A Clinical Trial to Study the Efficacy and Safety of Different Doses of Bone Marrow Derived Mesenchymal Stem Cells in Patients With Critical Limb Ischemia Due to Buergers DiseaseNo drug interventionstreatment2completed
NCT00488020
Stem Cells for Treating Critical IschemiaNo drug interventionstreatment1unknown_status
NCT00523731
ACPs in Severe PAD/CLI by Direct Intramuscular InjectionNo drug interventionstreatment1completed
NCT02786173
Peripheral Registry of Endovascular Clinical Outcomes "The PRIME Registry"No drug interventionsNot AvailableNot Availablecompleted
NCT01232673
Autologous Bone Marrow Stem Cell Transfer in Patients With Chronical Critical Limb Ischemia and Diabetic FootNo drug interventionstreatment2completed
NCT01663376
Safety and Effect of Adipose Tissue Derived Mesenchymal Stem Cells Implantation in Patients With Critical Limb IschemiaNo drug interventionstreatmentNot Availablecompleted
NCT06296576
Acceleration Time Assessment for Prediction of Critical Limb IschemiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT01794494
Prospective Observation Study of Outcome of Interventions for Critical IschemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT03809494
HemaTrate™ in the Treatment of Critical Limb IschemiaNo drug interventionstreatmentNot Availableterminated
NCT05971394
IBS Titan™ Sirolimus-eluting Iron Bioresorbable Peripheral Scaffold System Clinical TrialNo drug interventionstreatmentNot Availablerecruiting
NCT00403780
Randomized Study of Pregabalin for Pain Reduction in Patients With Rest Pain and Lower Limb Ischemiatreatment4terminated
NCT02498080
Drug Eluting Balloons PTA in Infra-popliteal Arteries in Patients With Critical Limb IschemiaNo drug interventionstreatmentNot Availableunknown_status
NCT01269580
Diabetic Foot and Vascular Progenitor CellsNo drug interventionsNot AvailableNot Availableunknown_status
NCT03448029
RECCORD (Recording Courses of Vascular Diseases) RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT01472289
Safety and Efficacy of Autologous Bone Marrow Mononuclear Cells in Patients With Severe Critical Limb IschemiaNo drug interventionstreatment1 / 2completed
NCT04594889
Comparison of Sirolimus vs Paclitaxel Drug Eluting Balloon for Below-the-knee Angioplasty in Critical Limb IschemiaNo drug interventionstreatmentNot Availableunknown_status
NCT06482892
A Single Arm Clinical Study Evaluating the Safety, Tolerability, and Efficacy of Multiple Intravenous Administration of TP03HN106 in Patients With Critical Limb IschemiaNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04534192
Investigating the Safety and Efficacy of the Treatment With the Non-compliant Jade Balloon in TASC C and D Athero-occlusive Infra-inguinal Disease in Patients With Chronic Limb Threatening Limb Ischemia From SingaporENo drug interventionstreatmentNot Availableunknown_status
NCT01745744
Application of Cell Regeneration Therapy With Mesenchymal Stem Cells From Adipose Tissue in Critical Chronic Ischemic Syndrome of Lower Limbs (CLI) in Nondiabetic Patients.No drug interventionstreatment2completed
NCT04027244
Leg Ischaemia Management CollaborationNo drug interventionsNot AvailableNot Availablerecruiting
NCT02395744
The COPPER-B TrialNo drug interventionstreatmentNot Availablecompleted
NCT03594344
Additional Hyperbaric Oxygen After Lower Extremity AmputationNo drug interventionstreatmentNot Availablerecruiting
NCT02539940
Elutax-SV Drug-eluting Balloons for Below-the-knee TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT02517840
Revascularization in Nonagenarian Patients With Critical Lower Limb IschaemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT06075940
Evaluation of the MAGNITUDE® Bioresorbable Drug-Eluting Scaffold in the Treatment of Patients With Below the Knee Disease in AustraliaNo drug interventionstreatmentNot Availablerecruiting
NCT06318767
Predictive Value of Systolic Rise Time of the Plantar Arch on the Risk of Major Adverse Limb Events (MALE) and Major Adverse Cardiovascular Events (MACE) in Peripheral Artery Disease (PAD) at Critical Ischaemia StageNo drug interventionsdiagnosticNot Availablerecruiting
NCT02388867
Matrix Metalloproteinases in Patients With Critical Limb Ischemia Undergoing Surgical RevascularizationNo drug interventionsdiagnosticNot Availablecompleted
NCT03636867
Laboratory, Cellular and Molecular Determinants of Clinical Success in Diabetic Patients With Critical Limb IschemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT00518401
Combination Stem Cell Therapy for the Treatment of Severe Leg IschemiaNo drug interventionstreatment1completed
NCT01870401
Lutonix DCB Versus Standard Balloon Angioplasty for Treatment of Below-The-Knee (BTK) ArteriesNo drug interventionstreatmentNot Availablecompleted
NCT06007469
Pedal Acceleration Time (PAT) as a Measure of Foot PerfusionNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03810469
Foot Perfusion Analysis to Predict Limb SalvageNo drug interventionsNot AvailableNot Availableunknown_status
NCT00883246
Study of SilverHawk®/TurboHawk® in Lower Extremity Vessels (DEFINITIVE™ LE)No drug interventionstreatmentNot Availablecompleted
NCT04191746
BEST vCLI RegistryNo drug interventionsNot AvailableNot Availablecompleted
NCT02336646
Cell Therapy With Mesenchymal Stem Cell in Ischemic Limb DiseaseNo drug interventionstreatment1completed
NCT03424746
Chelation Therapy in Diabetic Patients With Critical Limb IschemiaNo drug interventionsprevention0completed
NCT01019681
Efficacy and Safety of Umbilical Cord Blood Injection for Critical Limb IschemiaNo drug interventionstreatment1terminated
NCT04100681
Intermittent Negative Pressure; Impact on Peripheral Artery Disease and Intermittent ClaudicationNo drug interventionstreatmentNot Availableterminated
NCT04278014
Continuous Sciatic Block Nerve in the Management of Vascular Pain in Critical Ischemia of Lower Limbs PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT04312555
Alprostadil as an Adjuvant Therapy With Indirect Angiosomal Revascularization in Critical Limb Ischemia.treatment4unknown_status
NCT00767923
Validation of OxyVu for Assessing Level of Amputation With Comparison to Other ModalitiesNo drug interventionsNot AvailableNot Availableunknown_status
NCT04792008
YQ23 Study in Patients With Critical Limb IschaemiaNo drug interventionstreatment1 / 2terminated
NCT03970538
PROMISE II: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening IschemiaNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT02044003
Safety & Feasibility Study of Tack-It Device for Vessel Dissection RepairNo drug interventionstreatmentNot Availablecompleted
NCT00300690
Choice of Material for Above-Knee Femoro-Popliteal Bypass Prosthetic Graft (PopUp)No drug interventionstreatment4completed
NCT01867190
Study to Assess Efficacy and Safety of Bone Marrow Derived Stem Cells in Patients With Critical Limb IschemiaNo drug interventionstreatment2completed
NCT04110964
Evaluation of Safety and Tolerability of Libella Gene Therapy for Critical Limb Ischemia: AAV- hTERTNo drug interventionstreatment1unknown_status
NCT04073121
Investigating the Safety and Efficacy of the Treatment With Luminor DCB and Angiolite DES of iVascular in TASC C and D Tibial Occlusive Disease in Patients With Critical Limb IschemiaNo drug interventionstreatmentNot Availablecompleted
NCT02091921
Switch to Ticagrelor in Critical Limb Ischemia Anti-platelet Studyscreening1 / 2completed
NCT02474121
Safety and Efficacy of Autologous Concentrated Bone Marrow Aspirate for Critical Limb Ischemia - Continued AccessNo drug interventionsNot AvailableNot Availableno_longer_available
NCT05009602
Diagnostic Tools to Establish the Presence and Severity of Peripheral Arterial Disease in People With DiabetesNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02551679
ACP-01 in Patients With Critical Limb IschemiaNo drug interventionstreatment2completed
NCT02140931
Assessment of Blood-Borne Autologous Angiogenic Cell Precursors Therapy in Patients With Critical Limb IschemiaNo drug interventionstreatment2suspended