Chronic Cough (CC) (DBCOND0085805)

Identifiers

Synonyms
Chronic Cough / Chronic cough (finding) / Unexplained cough (finding) / Persistent cough / Persistent cough (finding) / Coughing / Cough / Coughing - function (qualifier value) / Cough (finding)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Benproperine
An antitussive indicated in the treatment of acute and dry cough, especially dry cough.
No drug targets
Terbutaline
A beta-2 adrenergic agonist used as a bronchodilator and to prevent premature labor.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02797756
Impact of Gastroesophageal Reflux and Aspiration on Airway Inflammation and Microbiome in Children With Chronic CoughNo drug interventionsNot AvailableNot Availablecompleted
NCT01858584
Prospective, Comparative, Randomized, Controlled Trial on the Efficacy of the Treatment of Gastroesophageal Reflux Infant With Magnesium AlginateNo drug interventionstreatmentNot Availableunknown_status
NCT04758351
Prospective Study on the Evaluation, Patient Reported Outcomes and Effectiveness of Treatment for Chronic CoughNo drug interventionsNot AvailableNot Availablerecruiting
NCT02196493
An Open Label Trial of Azithromycin in Chronic Productive Coughtreatment3unknown_status
NCT06378671
Single-center Clinical Study on the Safety and Effect of Bronchoscopic Cryotherapy in Patients With Chronic CoughNo drug interventionstreatmentNot Availablerecruiting
NCT05642559
Study for the Development and Validation of Chronic Cough Patient Perspective QuestionnaireNo drug interventionsNot AvailableNot Availablecompleted
NCT03482713
Study of Gefapixant (MK-7264) in Adult Japanese Participants With Unexplained or Refractory Chronic Cough (MK-7264-033)treatment2completed
NCT03449134
A Study of Gefapixant (MK-7264) in Adult Participants With Chronic Cough (MK-7264-027)treatment3completed
NCT04866563
A Study of Efficacy and Safety of AX-8 in Chronic CoughNo drug interventionstreatment2recruiting
NCT03638063
ATP and Capsaicin Cough Provocation Test in Chronic Cough and BronchiectasisNo drug interventionsNot AvailableNot Availableunknown_status
NCT04694963
A Multi-center Study to Determine the Prevalence and Influence of Pertussis on Subacute Cough in ShenzhenNo drug interventionsNot AvailableNot Availableunknown_status
NCT06503939
Etiology Analysis of Chronic Cough After COVID-19 Infection and Research on the Efficacy of ICS or ICS/LABANo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT04765722
Mepolizumab for the Treatment of Chronic Cough With Eosinophilic Airways Diseasestreatment4recruiting
NCT01252225
Lidocaine: Effect of Lidocaine in Chronic Coughtreatment4completed
NCT06376448
An Observational Study Using Novel Questionnaire to Characterize Cough Phenotypes in Patients With Chronic CoughNo drug interventionsNot AvailableNot Availablerecruiting
NCT03639727
Cough in Eastern and Central FinlandNo drug interventionsdiagnosticNot Availablecompleted
NCT04193176
Efficacy and Safety of Gefapixant (MK-7264) in Women With Chronic Cough and Stress Urinary Incontinence (MK-7264-042)treatment3completed
NCT01777867
Cough Reflex Sensitivity and Bronchial Hyper-responsivenessNo drug interventionsNot AvailableNot Availablecompleted
NCT04984304
Individualized Diagnosis and Treatment of Extraesophageal Reflux in Patients With Chronic CoughNo drug interventionstreatmentNot Availablerecruiting
NCT04654481
Study of AffloVest in At-Risk Respiratory Patients During COVID-19 PandemicNo drug interventionssupportive_careNot Availableterminated
NCT04861155
Validation and Evaluation of a Novel Cough Detection DeviceNo drug interventionsdiagnosticNot Availablecompleted
NCT01297790
Cough Responses to Tussive Agents in Health and DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT04193202
Efficacy and Safety of Gefapixant (MK-7264) in Adult Participants With Recent Onset Chronic Cough (MK-7264-043)treatment3completed
NCT06542484
The Real-world Treatment Satisfaction by Gefapixiant in RCCtreatmentNot Availablenot_yet_recruiting
NCT04110054
Evaluation of S-600918 in Adults With Refractory Chronic Coughtreatment2completed
NCT03449147
A Study of Gefapixant (MK-7264) in Adult Participants With Chronic Cough (MK-7264-030)treatment3completed
NCT01413698
Cough Count ValidationNo drug interventionsNot AvailableNot Availableunknown_status
NCT05362097
Analysis of the Reliability and Validity of the Chinese Version of CC-QoLNo drug interventionsNot AvailableNot Availablerecruiting
NCT03864328
A Phase 2b Study of Inhaled RVT-1601 for the Treatment of Persistent Cough in IPFNo drug interventionstreatment2terminated
NCT03787511
Chronic Cough and Small Fiber NeuropathyNo drug interventionsotherNot Availablerecruiting
NCT05689307
Validation Study With a Non-CE Marked Medical Device (MD)No drug interventionsdiagnosticNot Availableenrolling_by_invitation
NCT04525885
A Study of Gefapixant (MK-7264) in Adult Participants With Chronic Cough (MK-7264-030)-China Extensiontreatment3completed
NCT01807832
The Use of Capsaicin Challenge for Diagnosis, Monitoring and Follow-up of Chronic Cough.No drug interventionsdiagnosticNot Availableunknown_status
NCT05522699
Cough Suppressive Therapy in Patients With Chronic CoughNo drug interventionstreatmentNot Availablerecruiting
NCT00858624
Neurophysiology and Pharmacology of Cough Reflex Hypersensitivityhealth_services_researchNot Availablecompleted
NCT05274516
A Trial of HRS-2261 in Healthy Subjects After Single and Multiple Oral AdministrationNo drug interventionstreatment1completed
NCT03622216
A Dose Escalation Study of Bradanicline in Refractory Chronic Coughtreatment2completed
NCT06286163
Neuroinflammatory Interactions of ATP and P2X3 Receptor in the Airways of Chronic Cough PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT01865422
French Linguistic and Metric Validations of Parent-proxy QOL Chronic Cough Specific Questionnaire (PC-QOL)No drug interventionsNot AvailableNot Availablecompleted
NCT03172130
Sham CPAP vs. Straight CPAP for Chronic CoughNo drug interventionstreatmentNot Availablecompleted
NCT01432730
A Study to Assess the Efficacy of Gefapixant (MK-7264/AF-219), in Participants With Chronic Cough (MK-7264-006)treatment2completed
NCT05392192
A Clinical Trial to Evaluate the Safety and Efficacy in Subjects With Chronic CoughNo drug interventionstreatment2completed
NCT01566968
Novel Endpoints in Cough Challenge TestingNo drug interventionsNot AvailableNot Availablecompleted
NCT05813223
Effect of Gefapixant on Cough-related Brain Activity in Patients With Chronic Coughbasic_science0recruiting
NCT03696108
A Study of Gefapixant (MK-7264) in Japanese Adult Participants With Refractory or Unexplained Chronic Cough (MK-7264-038)treatment3completed