Solute carrier family 22 member 2

BE0003647ProteinHumansSLC22A2

Electrogenic voltage-dependent uniporter that mediates the transport of a variety of organic cations such as endogenous bioactive amines, cationic drugs and xenobiotics (PubMed:9260930, PubMed:9687576). It is acted on by 153 drugs in DrugBank.

Gene name
SLC22A2
UniProtKB entry
O15244Swiss-Prot
Cellular location
Basolateral cell membrane
Residues / weight
555 residues · 62,580 Da
Also known as
hOCT2 · OCT2 · Organic cation transporter 2

Resolves to

Protein
UniProtO15244UniProt nameS22A2_HUMAN
Gene
HGNCHGNC:10966NCBI Gene6582GenBank2281942GeneCardsSLC22A2
Pharmacology
IUPHAR/GtoPdb1020KEGGhsa:6582
Structure
PDB8ET9
Drugs

What you can answer from here — as of September 07, 2019

153DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
4Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
40GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
298+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Solute carrier family 22 member 2, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In