Glanzmann's Thrombasthenia (DBCOND0103516)

Identifiers

Synonyms

Glanzmann Thrombasthenia / Glanzmann’s thrombasthenia / Thrombasthenia / Glanzmann's Disease / Glanzmann's thromboasthenia / Glanzmann's thrombasthenia / Glanzmann thromboasthenia / Qualitative platelet defects / Thromboasthenia / Hereditary thrombasthenia / Glanzmann's thrombasthenia (disorder)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Coagulation factor VIIa Recombinant Human	A form of recombinant human coagulation Factor VII used to treat hemophilia A and B.	Coagulation factor Xtarget Tissue factortarget Tissue factor pathway inhibitortarget Vitamin K-dependent gamma-carboxylasetarget Coagulation factor VIItarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT01319851	Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation	Alefacept	treatment	Not Available	terminated
NCT02179359	Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies	No drug interventions	treatment	Not Available	recruiting
NCT06204042	Multinational Glanzmann Study	No drug interventions	Not Available	Not Available	not_yet_recruiting
NCT04595617	Anti-αIIbβ3 Immunization in Glanzmann Thrombasthenia: Prevalence and Associated Risk Factors: Thrombasthenia Anti-αIIbβ3 Antibodies Study (TAAS)	No drug interventions	diagnostic	Not Available	completed
NCT06211634	A Phase 1/2 Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of HMB-001 in Glanzmann Thrombasthenia	No drug interventions	prevention	1 / 2	recruiting
NCT03333486	Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer	Cyclophosphamide Fludarabine	treatment	2	active_not_recruiting
NCT00230165	The Genetics and Functional Basis of Inherited Platelet, White Blood Cell, Red Blood Cell, and Blood Clotting Disorders.	No drug interventions	Not Available	Not Available	recruiting
NCT04548791	Study of Coagulation Factor VIIa Marzeptacog Alfa (Activated) in Subjects With Inherited Bleeding Disorders	Coagulation factor VIIa Recombinant Human	treatment	1 / 2	terminated
NCT05315232	The Experiences of People Who Live With Glanzmanns Thrombasthenia.	No drug interventions	Not Available	Not Available	completed
NCT06234813	Targeting TFPI With Concizumab to Improve Haemostasis in Glanzmann Thrombasthenia Patients: an in Vitro Study	No drug interventions	treatment	Not Available	completed
NCT04119908	Videomicroscopy for the Prediction of Bleeding in Constitutional Haemorrhagic Diseases	No drug interventions	diagnostic	Not Available	recruiting
NCT01917708	Bone Marrow Transplant With Abatacept for Non-Malignant Diseases	Abatacept	supportive_care	1	completed
NCT03372993	Prospective, Non-interventional Study to Evaluate Immunogenicity of AryoSeven	No drug interventions	Not Available	Not Available	completed
NCT00697320	Observational Study on the Efficacy and Safety of NovoSeven® During "Real-life" Usage in Germany	Coagulation factor VII human Coagulation factor VIIa Recombinant Human	Not Available	Not Available	completed
NCT01476423	Observational Registry of the Treatment of Glanzmann's Thrombasthenia	Coagulation factor VII human	Not Available	Not Available	completed
NCT01876745	A Study to Evaluate Safety and Efficacy of NovoSeven® in Patients With Glanzmann's Thrombasthenia in Japan	Coagulation factor VII human Coagulation factor VIIa Recombinant Human	Not Available	Not Available	completed
NCT01561417	Bioequivalence of NovoSeven® and a NovoSeven® Formulation Stable at Room Temperature in Healthy Male Subjects	Coagulation factor VII human	treatment	1	completed