Progressive Multifocal Leucoencephalopathy (PML) (DBCOND0120281)

Identifiers

Synonyms
Progressive multifocal leucoencephalopathy / Progressive multifocal leukoencephalopathy (PML) / Leukoencephalopathy, Progressive Multifocal / Progressive Multifocal Leukoencephalopathy / Progressive multifocal leukoencephalopathy (disorder)

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT03969550
Do CCR5 Antagonists Improve the Overall Survival of Patients With AIDS-related Progressive Multifocal Leucoencephalopathy?No drug interventionsNot AvailableNot Availablecompleted
NCT00002270
A Pilot Study of the Efficacy of Recombinant Alpha Interferon (IFN-A2b) and Zidovudine (AZT) in the Treatment of Progressive Multifocal Leukoencephalopathy (PML) Complicating HIV-1 InfectiontreatmentNot Availablecompleted
NCT00001048
Comparison of Anti HIV Drugs Used Alone or in Combination With Cytosine Arabinoside to Treat Progressive Multifocal Leukoencephalopathy (PML) in HIV-Infected Patientstreatment2completed
NCT01211665
Corticosteroids for Immune Reconstitution Inflammatory Syndrome (IRIS)treatment4terminated
NCT00002274
A Study of ddI in Patients With AIDS Who Become Sicker While Taking ZidovudinetreatmentNot Availablecompleted
NCT00000945
A Study to Evaluate the Use of Cidofovir (an Experimental Drug) for the Treatment of Progressive Multifocal Leukoencephalopathy (PML) in AIDS PatientstreatmentNot Availablecompleted
NCT00120367
Early Intensification of Antiretroviral Therapy Including Enfuvirtide in HIV-1-Related Progressive Multifocal Leucoencephalopathy (ANRS125)treatment2completed
NCT00002395
Safety and Effectiveness of Topotecan HCl to Treat HIV-Infected Patients With AIDS-Related Progressive Multifocal Leukoencephalopathy (PML)treatment2completed
NCT01132053
Role of Inflammation in Progressive Multifocal Leukoencephalopathy (PML)No drug interventionsNot AvailableNot Availablecompleted
NCT02694783
Adoptive Cellular Immunotherapy for Progressive Multifocal Leukoencephalopathy With Ex Vivo Generated Polyomavirus-Specific T-CellsNo drug interventionstreatment0completed
NCT04781309
NT-I7, a Long-Acting Recombinant IL-7 Molecule, as an Immune Reconstitution Strategy for Lymphopenia in Patients With Progressive Multifocal Leukoencephalopathytreatment0recruiting
NCT04091932
Treatment of PD-1 Inhibitor in AIDS-associated PMLtreatment2unknown_status
NCT05541549
A Phase 2 Study Evaluating JCPyV-specific T Cell Therapy for PMLtreatment2not_yet_recruiting
NCT04453917
Dynamics of T Cell Expression of Immune Checkpoint Molecules in Progressive Multifocal LeukoencephalopathyNo drug interventionsbasic_scienceNot Availablerecruiting
NCT01211639
Genetic Evaluation of Natalizumab-Treated Patients With Progressive Multifocal LeukoencephalopathyNo drug interventionsNot AvailableNot Availableterminated
NCT01730131
Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)No drug interventionsNot AvailableNot Availablerecruiting
NCT05849467
Central Nervous System Uptake of Anti-CD8+ T Cell Minibodies in Multiple Sclerosis and Progressive Multifocal LeukoencephalopathyNo drug interventionstreatment1recruiting
NCT06276504
Pembrolizumab in Progressive Multifocal Leukoencephalopathy (PML) in Immunocompromised Patients Without HIV InfectionNo drug interventionstreatment2 / 3not_yet_recruiting
NCT02895581
Retrospective Study of the Survival of Patients Suffering From Hiv-related Progressive Multifocal LeukoencephalopathyNo drug interventionsNot AvailableNot Availablecompleted
NCT00746941
Study to Explore the Effect of Mefloquine in Participants With Progressive Multifocal Leukoencephalopathy (PML)No drug interventionstreatment1 / 2terminated
NCT02004444
JC Virus Reactivation in Multiple SclerosisNo drug interventionsNot AvailableNot Availablecompleted
NCT03399981
Tysabri Observational Cohort Study - Multiple Sclerosis (MS) RegistriesNo drug interventionsNot AvailableNot Availablecompleted