Asthma, Allergic (DBCOND0047182)

Identifiers

Synonyms
Asthma Atopic / Atopic Asthma / Allergic Asthma / Allergic asthma (disorder) / Asthma extrinsic / Extrinsic asthma / Asthma / Immunoglobulin E-mediated allergic asthma (disorder) / Other and unspecified asthma / Unspecified asthma / Unspecified asthma, uncomplicated / Bronchial asthma / Asthma, unspecified / Asthma bronchial / Asthma NOS / Asthma (disorder) / Asthmatic / Bronchitic asthma

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Guaifenesin
An expectorant commonly found in OTC products for the symptomatic relief from congested chests and coughs associated with cold, bronchitis, and/or other breathing illnesses.
Ketotifen
A histamine H1 receptor blocker and mast cell stabilizer used to treat mild atopic asthma and allergic conjunctivitis.
Oxatomide
An antihistamine indicated in the treatment and prevention of allergic symptoms.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT03780387
Identification of Allergic Asthmatics Reactive to Felis Catus (Cat Hair) Allergen InhalationNo drug interventionsbasic_science0terminated
NCT01448954
A Study to Evaluate Safety, Tolerability and Pharmacokinetics of ADC3680B in Subjects With Partly Controlled Atopic AsthmaNo drug interventionstreatment2completed
NCT01890161
A Phase IIa Repeat Dose AXP1275 vs Placebo Cross-over Trial With Pulmonary Allergen Challenge in Adults With AsthmaNo drug interventionstreatment2completed
NCT00861211
Safety and Efficacy Study of Oral Senicapoc on Allergen Challenge in Atopic Asthmatic Subjectstreatment2completed
NCT00671593
Differential Gene Expression in Lung and Peripheral Blood After Inhaled Allergen Challengebasic_science1terminated
NCT01049178
Randomized Controlled Trial of Silymarin in Asthmatreatment2 / 3withdrawn
NCT05098600
The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech RepublicNo drug interventionsNot AvailableNot Availablecompleted
NCT00784459
The Effect of Inhibition of B7-mediated Costimulation on Allergic Airway Inflammation in Mild Atopic Asthmaticsbasic_science2completed
NCT03603522
Probiotics and Capsaicin Evoked CoughsNo drug interventionstreatmentNot Availablecompleted
NCT02758548
Determination of Accuracy in Measurement of Total Immunoglobulin E Using a Test Device in Atopic SubjectsNo drug interventionsdiagnostic2completed
NCT03928431
Restoration of Microbiota in NeonatesNo drug interventionstreatmentNot Availablerecruiting
NCT03665701
Characterization of the Inhibitory Effects of Fevipiprant (QAW039) on Activation of Eosinophils and ILC2 Cells by Prostaglandin D2 MetabolitesNo drug interventionsbasic_scienceNot Availablecompleted
NCT00644514
Genetics of Asthma - Bronchoscopy StudiesNo drug interventionsbasic_science1terminated
NCT01545245
Effects of Preventive Treatment for Respiratory Syncytial (RS) Virus Infection During Infancy on Later Atopic Asthma in Preterm InfantsNo drug interventionsNot AvailableNot Availablecompleted
NCT04728711
A Double Masked, Placebo Controlled, Single Center, Randomized Clinical Trial to Assess the Safety and Efficacy of Subjects With Mild Asthma Induced by the Bronchial Allergen Challenge (BAC)No drug interventionstreatment2completed
NCT01179256
Effect of Supplemental Oral Curcumin in Patients With Atopic AsthmaNo drug interventionstreatmentNot Availablecompleted
NCT02327234
Airway Response to Repeat Allergen Challenge and the Effect of Ibuprofen in Mild Atopic Asthmabasic_scienceNot Availablecompleted
NCT04397081
Atopic Diseases & Human Papilloma VirusNo drug interventionsNot AvailableNot Availablecompleted
NCT01420003
Kinetics of IgE Memory B Cells, Plasmablasts and Plasma Cells After Whole Lung Allergen Challenge in Mild AsthmaticsNo drug interventionsbasic_scienceNot Availablecompleted
NCT03112577
Study of REGN3500 and Dupilumab in Patients With Asthmatreatment1completed
NCT03455959
Lung-Resident Memory Th2 Cells in AsthmaNo drug interventionsbasic_scienceNot Availablerecruiting
NCT02953106
Effects of Intranasal Fluticasone Plus Azelastine on Airway Inflammation in Patients With Asthma & Allergic Rhinitistreatment4terminated
NCT02990117
ICS Treatment Compliance of Asthma PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT05478824
IL13 Signaling in Allergic AsthmaNo drug interventionsNot AvailableNot Availablerecruiting
NCT05720325
Dupilumab Effects Against Aeroallergen Challengebasic_science2recruiting
NCT03705325
Evaluating Asthma Exacerbation-induced Changes in Lung Function With a Home-based SpirometerNo drug interventionsotherNot Availablecompleted
NCT01104012
Validation of Proteomic Analyses for Allergic Asthma and RhinitisNo drug interventionsNot AvailableNot Availablecompleted
NCT03983603
Plant Stanol Esters and Preventing Asthma SymptomsNo drug interventionspreventionNot Availablerecruiting
NCT04435990
Efficacy and Safety Evaluation for the Treatment of Allergy Against MitesNo drug interventionstreatment3recruiting
NCT04898283
Efficacy and Safety Evaluation of the Treatment of Allergy Against Cupressaceae and Grasses.No drug interventionstreatment3recruiting
NCT04109807
Effects of Low Dose Ozone on Airway Inflammatory Responses in Adults With Asthma - Sedentary Nasal Ozone (Asthma SNOZ)No drug interventionsbasic_scienceNot Availablesuspended
NCT04035109
Anakinra as a Rescue Treatment for Allergic Inflammationtreatment1 / 2withdrawn
NCT04891237
Efficacy and Safety Evaluation for the Treatment of Allergy Against Grass and Olive PollenNo drug interventionstreatment3recruiting
NCT05740748
Tezepelumab and Methacholine Airway Hyperresponsiveness in Participants With Mild Allergic Asthmatreatment2not_yet_recruiting
NCT05352126
Effects of Puressentiel Purifying Spray on Asthma Control in Patients With Mild to Moderate Allergy-induced Asthma.No drug interventionspreventionNot Availableunknown_status
NCT06027073
Biologics and Sublingual Immunotherapytreatment4not_yet_recruiting
NCT06063044
Food-specific IgG4-guided Elimination Diets Improve Allergy Symptoms in ChildrenNo drug interventionsNot AvailableNot Availablecompleted
NCT03468790
Anti-IgE Monoclonal Antibody Treatment in Patients With Allergic Asthma.treatment3completed
NCT03563521
Identifying Serum Cytokine Profiles of Distinct Inflammatory Phenotypes in Severe AsthmaNo drug interventionsNot AvailableNot Availablecompleted
NCT01365533
A Study to Evaluate the Effect of Roflumilast on Airway Inflammation and Function Following Allergen Challenge in Subjects With Allergic Asthmatreatment2completed
NCT01318954
The Effect of Allergen Immunotherapy on Exhaled Nitric Oxide in Adult Patients With Asthma and Allergic RhinitisNo drug interventionsNot AvailableNot Availablecompleted
NCT02023151
Predicting the Clinical Response to Omalizumab With Anti-Immunoglobulin E (IgE) Ab Response or Syk Expression in Basophilstreatment4completed
NCT04264377
Towards Targeting the ORigin of the Inflammatory Cascade in Allergic AsthmaNo drug interventionsNot AvailableNot Availableunknown_status
NCT01776177
The REALITY Study - a Real-life Long-term Analysis of Xolair TherapyNo drug interventionsNot AvailableNot Availableunknown_status
NCT06267261
Efficacy of Face Mask in Reducing Respiratory Allergic Symptoms in Birch-allergic Subjects in ALYATEC Exposure ChamberNo drug interventionsotherNot Availablecompleted
NCT00535028
A Phase IIa Study of Subcutaneous AER 001 on Antigen Challenge In Atopic Asthmatic Subjects (28 Day Study)No drug interventionstreatment2completed
NCT02504528
Bronchial Allergen Provocation Tests in Asthmatics in GuangzhouNo drug interventionsdiagnosticNot Availablecompleted
NCT05400811
Efficacy and Safety Evaluation for the Treatment of HDM Induced Allergic Asthma and Rhinitis/RhinoconjunctivitisNo drug interventionstreatment3not_yet_recruiting
NCT02911688
Effect of Gamma Tocopherol Enriched Supplementation on Response to Inhaled O3 Exposuretreatment2completed
NCT00980707
Utility of Versican and Hyaluronan Measurement in Induced Sputum as Biomarkers of Asthmadiagnostic4completed
NCT00396409
Efficacy/ Safety of Omalizumab in Patients With Seasonal Allergic Asthma and Seasonal Allergic Rhinoconjunctivitistreatment3completed
NCT01612715
Analysis of Fel d 1-specific T Cells After Airway Allergen Challenge in AsthmaNo drug interventionsNot AvailableNot Availablecompleted
NCT02764437
AsthMatic Inflammation and Neurocircuitry Activation (MINA)No drug interventionsNot AvailableNot Availablecompleted
NCT02096237
Extracorporeal SPecific IgE Removal From the Plasma of Allergic Asthma Patients (ESPIRA-study)No drug interventionstreatmentNot Availablecompleted
NCT04442932
abioSCOPE IgE Assay to Aid in the Diagnosis of AllergiesNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01155700
Pharmacokinetics and Pharmacodynamics, Efficacy and Safety of Omalizumab in Japanese Children (6 - 15 Years)treatment3completed
NCT00421018
Optimization of Asthma Treatment Through Exhaled NO for Increased Asthma-Related Quality of Life (NOAK)treatmentNot Availablecompleted
NCT00214019
The Effect of Salmeterol on Eosinophil (EOS) FunctiontreatmentNot Availablecompleted
NCT04619017
Airway Immune Response to Allergens (Use Lay Language Here)No drug interventionsbasic_science1active_not_recruiting
NCT01821716
Biological Standardization of Dermatophagoides Pteronyssinus Allergen ExtractNo drug interventionsdiagnostic2completed
NCT01328886
Long-term Safety, Tolerability and Efficacy of Omalizumab in Japanese Childrentreatment3completed
NCT01536522
Asthma Inflammation ResearchNo drug interventionsother0enrolling_by_invitation
NCT00490425
Prevention of Asthma and Allergy by Probiotic Lactobacillus GGprevention4completed
NCT00670930
Efficacy of Omalizumab in Adults (18-60 Years of Age) With Moderate-Severe, Persistent Allergic Asthma, Despite Receiving Inhaled Corticosteroids and Long Acting Beta-agoniststreatment4completed
NCT00813748
Pharmacosurveillance Data Repository of Patients With and Without History of Anaphylactic Reactions Subsequent to Xolair DosingNot AvailableNot Availablecompleted
NCT01125748
A Study Evaluating the Persistency of Response With or Without Xolair (Omalizumab) After Long-term Therapytreatment4completed
NCT00581048
Study on the Role of Treatment With Vitamin E on Asthmatic Responses in Allergic Asthmaticsbasic_scienceNot Availablecompleted
NCT06438757
Trial of JYB1904 in Allergic Asthmatreatment2recruiting
NCT03850626
Validation of Combined Symptom Medication Score (cSMS) in Allergic PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT05008965
Evaluate the Efficacy and Safety of FB825 in Adult With Allergic Asthmatreatment2recruiting
NCT02648074
Eosinophil Induced Remodelling in AsthmaNo drug interventionsbasic_scienceNot Availablecompleted
NCT02541331
Efficacy Of Bacterial Lysate In Asthmatic ChildrenNo drug interventionsprevention3completed
NCT00535431
Effects of AER 001 Administered by Nebulization on Antigen Challenge in Atopic Asthmaticstreatment2completed
NCT02767973
To Identify Persons Who Are Susceptible to WSP-induced Inflammation and Examine the Role of GSTM1 and Other Factors in This SusceptibilityNo drug interventionsscreeningNot Availablerecruiting
NCT00492076
Efficacy and Safety Trial of Subcutaneous Immunotherapy in Mite Induced AsthmaNo drug interventionsprevention4completed
NCT00485576
Safety and Efficacy Study of Eculizumab in Patients With Mild Allergic Asthmaprevention2completed
NCT05297760
Intralymphatic Immunotherapy With Polvac Grass & Rye Allergen ExtractNo drug interventionstreatment1 / 2active_not_recruiting
NCT04673591
Effects of Tregalizumab on Allergen-induced Airway Responses and Airway Inflammation in Asthmatic Patientstreatment2completed
NCT00622362
Subcutaneous-Sublingual Immunotherapy With Depigmented and Polymerized Dermatophagoides Pteronyssinus Allergen ExtractNo drug interventionstreatment2terminated
NCT04663880
Validation of Strasbourg Environmental Exposure Chamber ALYATEC in Mite Allergic Subjects With AsthmaNo drug interventionsotherNot Availablecompleted
NCT00283504
A Description of Inflammatory Cell Types In Moderate to Severe Pediatric Asthma: Eosinophilic and Non Eosinophilic Sputum Markers While on Anti-IgE Therapydiagnostic4completed
NCT05641272
Clinical Trial to Evaluate the Efficacy and Safety of Polymerized, Mannan-Conjugated Dermatophagoides Allergen ExtractNo drug interventionsprevention2 / 3not_yet_recruiting
NCT02965612
Specific Immunotherapy for Allergic ChildNo drug interventionstreatmentNot Availableunknown_status
NCT04567212
Gender Differences and SNPs in Asthmatic PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT01703312
A Study Evaluating the Efficacy of QGE031 Compared to Omalizumab in Patients With Allergic Asthmatreatment1 / 2completed
NCT01144910
The Long-term Prognosis of Moderate to Severe Bronchial Hyperresponsiveness (BHR) in Asthmatic Preschool ChildrenNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01669681
Cobra (Severe Asthma)Medical-economicNo drug interventionsNot AvailableNot Availablecompleted
NCT03119714
Pemirolast in Allergen Challenge (PEMAG)treatment2terminated
NCT01976208
Safety and Efficacy Study of Omalizumab to Treat Allergic Asthmatreatment2 / 3completed
NCT06151938
Evaluate Measurement Instruments Relevance in Assessing Effectiveness of ACARIZAX® in House Dust Mite Allergic RhinitisNot AvailableNot Availableenrolling_by_invitation
NCT00781443
A Study to Evaluate MILR1444A in the Prevention of Allergen-Induced Airway Obstruction in Adults With Mild Allergic Asthmatreatment2completed
NCT04259164
Anti-inflammatory Effects Glycopyrroniumtreatment3completed
NCT03213184
Children's Respiratory and Environmental WorkgroupNo drug interventionsNot AvailableNot Availablecompleted
NCT00829179
Role of RhuMab-E25 in Reducing Exhaled Nitric Oxide (NO) in Allergic Asthmabasic_science3completed
NCT04476433
Intervention in Chronic Pediatric Patients and Their Families.No drug interventionspreventionNot Availablecompleted
NCT03820154
Diagnostic Equivalence of the Skin Prick Test Tape vs. Conventional Skin PrickTestNo drug interventionsdiagnosticNot Availableunknown_status
NCT06494345
A Study of Genolair in Two Dosage Forms (Solution and Lyophilisate) and Xolair® in Healthy Volunteersother1completed
NCT01479205
Induction of Allergen Specific Bronchial Immunotolerance After Specific ImmunotherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT00550797
Study to Evaluate the Safety and Efficacy TPI ASM8 in Subjects With Asthmatreatment2completed
NCT03431961
Nasal Allergen Challenge - Reproducibility of Biomarkers and Effect of Topical Steroid Treatmentbasic_scienceNot Availableunknown_status
NCT03307278
House Dust Mite Induced Inflammasome Activation on Corticosteroid ResistanceNo drug interventionsbasic_scienceNot Availablewithdrawn
NCT04352088
Immune Response Features in Allergic Airway DiseasesNo drug interventionsNot AvailableNot Availableunknown_status
NCT05749237
The Impact of Breath Exercises by Telemedicine in Patients Aged 8-18 Years With a Diagnosis of AsthmaNo drug interventionstreatmentNot Availablerecruiting
NCT04878237
Kinetics of Nasal Cytokine Responses to Mechanical StimulationNo drug interventionsbasic_scienceNot Availablecompleted
NCT03388359
Role of Extracellular Matrix in the Development of Airway Remodeling in AsthmaNo drug interventionsbasic_scienceNot Availableunknown_status
NCT01392859
Characterization of the Role of Histamine in Children With Asthmadiagnostic2 / 3completed
NCT00515775
Influence of a Inhaled Corticosteroid Therapy Versus Corticosteroid + LABA Therapy on the FeNO of Asthmatic ChildrenNo drug interventionsNot AvailableNot Availablecompleted
NCT05813470
Efficacy and Safety of Zerafil® (Omalizumab) in Participants With Uncontrolled Moderate to Severe Allergic Asthmatreatment3completed
NCT04648813
Tiotropium Efficacy Against Allergen Induced Early Asthmatic Responsestreatment4completed
NCT04109534
Effect of a Dietary Fatty Acid Supplementation on Symptoms and Bronchial Inflammation in Patients With AsthmaNo drug interventionstreatmentNot Availableunknown_status
NCT00434434
A Study of Omalizumab in the Prevention of Allergen Induced Airway Obstruction in Adults With Mild Allergic Asthmatreatment2completed
NCT04389034
Influence of Specific Immunotherapy With Pollinex Quattro (Tree-/Grass Pollen) on Allergen-specific Immunoglobulin E (IgE) LevelsNo drug interventionsNot AvailableNot Availablecompleted
NCT00208234
Effect of Xolair on Airway Hyperresponsivenesstreatment4unknown_status
NCT04678063
Validation of Strasbourg Environmental Exposure Chamber ALYATEC in Cat Allergic Subjects With AsthmaNo drug interventionsotherNot Availablecompleted
NCT05191186
Documentation of Efficacy of Intralymphatic Allergen ImmunotherapyNo drug interventionstreatment3unknown_status
NCT00507039
Safety and Repeatability of Bronchial Challenge With Grass-pollenNo drug interventionsNot AvailableNot Availablecompleted
NCT05186025
Tyrosine Allergoid Paediatric and Adult StudyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT01544348
A Phase 1, Randomized, Placebo-controlled, Dose-escalation Safety Study of MEDI4212 in Subjects With IgE >= 30 IU/mLtreatment1completed
NCT00380926
Fish Oil and Asthma in House Dust Mite Allergytreatment2 / 3completed
NCT00999466
The Tolerability and Effects of AZD8848 in Allergic Asthma Subjects Challenged With Inhaled Allergentreatment2completed
NCT00406965
A Study to Evaluate the Safety and Efficacy of HAE1 in Subjects With Moderate to Severe Allergic AsthmaNo drug interventionstreatment2completed
NCT05192720
Andosan in Allergic and Asthma PatientsNo drug interventionsotherNot Availablecompleted
NCT04401631
Analytical Validation of the abioSCOPE Device With an IgE Test Panel: Point-of-Care Precision, Sample Type Comparison and Method CorrelationNo drug interventionsNot AvailableNot Availablewithdrawn
NCT03776773
Impact of Pollution on Allergic Rhinitis and Sleep Quality: the POLLAR StudyNo drug interventionsotherNot Availablecompleted
NCT02908360
Study of the Frequency and of the Regulatory Function of Positive T Lymphocytes Dual CD4CD8aa (DP8a) Specific to a Bacteria of the Intestinal Microbiota (Faecalibacterium Prausnitzii) in Atopic Dermatitis, Asthma and Allergic RhinitisNo drug interventionsNot AvailableNot Availablecompleted
NCT01699594
Change in Airway Responsiveness After Allergen Exposurebasic_scienceNot Availablecompleted
NCT01019291
Role of Indoor Pollutants on House Dust Mite Allergic AsthmaNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00565591
Study Mild Intermittent Asthma to Assess the Topical Safety and Tolerability of Albuterol Sulfate Acu-30™ DPItreatment1completed
NCT06486662
A Clinical Study Investigating OM-85-IN Safety and Tolerability in Healthy Volunteers and Mild Allergic Asthma Patientstreatment1recruiting
NCT04902989
Environmental Pollutants and Their Effects on Respiratory AllergyNo drug interventionsNot AvailableNot Availableunknown_status
NCT00736801
Effect of Salmeterol on Brain-Derived Neurotrophic Factor (BDNF) Concentrations in Asthmabasic_scienceNot Availablecompleted
NCT04699604
A Histamine Pharmacodynamic Biomarker to Guide Treatment in Pediatric Asthma (HAS3)treatment3recruiting
NCT03861910
Dietary Choice for the Management of Cow's Milk Allergy Influences Other Allergic ManifestationsNo drug interventionsNot AvailableNot Availablecompleted
NCT01353755
2nd Pivotal Study rPhleum - Adults and Adolescents With Rhinoconjunctivitis +/-Controlled AsthmaNo drug interventionstreatment3completed
NCT00710450
Effect of Montelukast on Basophils, In-vitroNo drug interventionsNot AvailableNot Availableunknown_status
NCT00652223
Effect of an Allergen Vaccine in Patients With Allergic Rhino-Conjunctivitis and Asthma Due to House Dust Mite AllergyNo drug interventionstreatment1 / 2completed
NCT05424523
Effectiveness and Safety of Omalizumab in Children With Allergic Asthma.Not AvailableNot Availablecompleted
NCT02214303
The Role of Th9 Cells and Eosinophils Activity in Allergic Airway DiseasesNo drug interventionsNot AvailableNot Availableunknown_status
NCT00267202
Study to Evaluate the Effect of Omalizumab on Improving the Tolerability of Specific Immunotherapy in Patients With Persistent Allergic Asthmatreatment4completed
NCT04542902
Non-coding RNAs Analysis of Eosinophil Subtypes in AsthmaNo drug interventionsbasic_scienceNot Availableunknown_status