Penicillin-binding protein 1B

BE0000488ProteinEscherichia coli (strain K12)mrcB

Cell wall formation. It is acted on by 21 drugs in DrugBank.

Gene name
mrcB
UniProtKB entry
P02919Swiss-Prot
Cellular location
Cell inner membrane
Residues / weight
844 residues · 94,292 Da
Also known as
Murein polymerase · PBP-1b · pbpF · ponB

Resolves to

Protein
UniProtP02919UniProt namePBPB_ECOLI
Gene
NCBI Gene944843GenBank42468
Pharmacology
KEGGecj:JW0145
Structure
PDB3FWLPDB3VMA
Drugs

What you can answer from here — as of September 07, 2019

21DrugsApproved to experimental, with action, bond type and pharmacological action
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13GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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46+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Penicillin-binding protein 1B, how selective are they, and which programs against it are still in active trials?

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