| Clemastine | An antihistamine with sedative and anticholinergic effects used to treat the symptoms of allergic rhinitis. |
| Cetirizine | A selective Histamine-1 antagonist drug used in allergic rhinitis and chronic urticaria. |
| Terfenadine | For the treatment of allergic rhinitis, hay fever, and allergic skin disorders. |
| Buclizine | For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems). |
| Doxylamine | An antihistamine used to treat insomnia and allergy symptoms and is used with pyridoxine in the treatment of nausea and vomiting in pregnancy. |
| Thiethylperazine | For the treatment or relief of nausea and vomiting. |
| Dexbrompheniramine | An antihistamine used to treat allergy symptoms including upper respiratory tract symptoms. |
| Triprolidine | A sedating antihistamine combined with pseudoephedrine and guaifenesin in various types of cold and allergy medications to relieve allergy symptoms, hay fever and common cold symptoms, and to aid in sleep. |
| Cyproheptadine | A combined serotonin and histamine antagonist used in the treatment of allergic symptoms, for appetite stimulation, and off-label in the treatment of serotonin syndrome. |
| Loratadine | A second generation antihistamine used to manage the symptoms of allergic rhinitis. |
| Astemizole | A second generation antihistamine used to treat allergy symptoms. |
| Trimethobenzamide | An antiemetic used to treat postoperative nausea and vomiting and nausea associated with gastroenteritis. |
| Azatadine | An H1 receptor antagonist used to treat perennial and allergic rhinitis as well as eustachian tube congestion. |
| Meclizine | A histamine H1 antagonist used to treat nausea, vomiting, and dizziness associated with motion sickness. |
| Carbinoxamine | A first generation antihistamine used to treat allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, allergic reactions, and mild allergic reactions. |
| Brompheniramine | A histamine H1 antagonist used to treat coughs, upper respiratory symptoms, and nasal congestion associated with allergies and the common cold. |
| Methdilazine | Used for the symptomatic relief of hypersensitivity reactions and particularly for the control of pruritic skin disorders |
| Ketotifen | A histamine H1 receptor blocker and mast cell stabilizer used to treat mild atopic asthma and allergic conjunctivitis. |
| Fexofenadine | A selective H1-antagonist for the symptomatic treatment of seasonal allergic rhinitis and chronic idiopathic urticaria. |
| Desloratadine | A second generation tricyclic antihistamine used to treat seasonal and non seasonal allergic rhinitis, pruritus, and urticaria. |
| Azelastine | A histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis. |
| Promethazine | A first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness. |
| Mequitazine | For the treatment of Hay fever, urticaria (hives) and allergic rhinitis |
| Diphenhydramine | A H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes. |
| Chlorpheniramine | A histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies. |
| Diphenylpyraline | An antihistamine used for the treatment of allergic rhinitis, hay fever, and allergic skin disorders. |
| Cyclizine | An antihistamine and antiemetic drug used for the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo. |
| Bromodiphenhydramine | For management of symptoms related to hay fever and other types of allergy and used to help bring up phlegm, thin secretions, and make a cough productive. |
| Alimemazine | An antihistamine agent used to prevent and relieve allergic conditions which cause pruritus and other allergic skin conditions, including urticaria. |
| Phenindamine | Used to treat sneezing, runny nose, itching, watery eyes, hives, rashes, itching, and other symptoms of allergies and the common cold. |
| Methapyrilene | Methapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979. |
| Thenalidine | Withdrawn from the Canadian, US, and UK markets in 1963 due to concerns involving neutropenia. |
| Levocetirizine | An H1-receptor antagonist used to treat symptoms associated with chronic allergic rhinitis and uncomplicated cases of chronic idiopathic urticaria. |
| Antazoline | An antihistamine agent used for the symptomatic treatment of nasal congestion and allergic conjunctivitis. |
| Chloropyramine | For the treatment of allergic conjunctivitis, allergic rhinitis, bronchial asthma, and other atopic (allergic) conditions. |
| Isothipendyl | For the topical treatment of itching associated with allergic reactions. |
| Chlorcyclizine | Chlorcyclizine is a first generation phenylpiperazine class antihistamine used to treat urticaria, rhinitis, pruritus, and other allergy symptoms. Chlorcyclizine also has some local anesthetic, anticholinergic, and antiserotonergic properties, and can... |
| Acrivastine | An antihistamine agent used for the symptomatic relief of seasonal allergic rhinitis such as sneezing, rhinorrhea, pruritus, lacrimation, and nasal congestion. |
| Thonzylamine | Thozylamine is indicated for use in the symptomatic control of allergic rhinitis or other upper respiratory allergic symptoms [FDA Label]. It is typically a part of combination over the counter... |
| Bilastine | A peripheral histamine H1-antagonist used to treat seasonal allergic rhinitis and chronic spontaneous urticaria. |
| Rupatadine | A selective histamine H1 receptor antagonist and platelet activating factor (PAF) antagonist used to treat allergic rhinitis. |
| Ebastine | Ebastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria. |
| Mizolastine | Mizolastine is under investigation in clinical trial NCT01928316 (A Bioequivalence Study of Domestic (Made in China) and Imported Mizolastine Tablets in Healthy Volunteers). |
| Oxatomide | Oxatomide has been used in trials studying the treatment of Muscular Dystrophy, Duchenne. |
| Pimethixene | Pimethixene is approved for use in Brazil and is marketed under the trade name Muricalm. It is an anticholinergic used in the treatment of bronchitis. |
| Talastine | Not Annotated |
| Thiazinam | Not Annotated |
| Deptropine | Not Annotated |
| Histapyrrodine | Not Annotated |
| Bamipine | Not Annotated |
| Sequifenadine | Not Annotated |
| Dexchlorpheniramine | Dexchlorpheniramine is a potent S-enantiomer of chlorpheniramine. The salt form dexchlorpheniramine maleate as the active ingredient is available as a prescription drug indicated for adjunctive therapy for allergic and anaphylactic... |
| Tritoqualine | Not Annotated |
| Quifenadine | Not Annotated |
| Mebhydrolin | Not Annotated |
| Oxomemazine | Not Annotated |
| Hydroxyethylpromethazine | Not Annotated |
| Pyrrobutamine | Not Annotated |
| Tripelennamine | A histamine H1 antagonist used to treat hypersensitivity reactions, coughs, and the common cold. |
| Pheniramine | An antihistamine used to treat allergic rhinitis and pruritus. |
| Mepyramine | An antihistamine agent used for the symptomatic treatment of allergy, hypersensitivity reactions, and pruritic skin disorders. |
| Dimetindene | Indicated as symptomatic treatment of allergic reactions: urticaria, allergies of the upper respiratory tract such as hey fever and perennial rhinitis, food and drug allergies; pruritus of various origins, except... |
| Chlorphenoxamine | Chlorphenoxamine is marketed under the name Phenoxene. It is an antihistamine and anticholinergic used to treat itching as well as for its antiparkinsonian effect. |