Anti-Acne Preparations

Anti-Acne Preparations
Accession Number

Not Available

ATC Classification
DrugDrug Description
MeclocyclineA tetracycline antibiotic indicated in the treatment of susceptible skin infections, bacterial vaginitis, vulvovaginitis, and cervicitis.
AdapaleneA third-generation topical retinoid with anti-comedogenic, comedolytic, and anti-inflammatory properties used to treat acne vulgaris in adolescents and adults.
Azelaic acidA saturated dicarboxylic acid used to treat mild to moderate acne vulgaris.
SulfacetamideA sulfonamide used to treat inflammatory ocular conditions and acne vulgaris.
TretinoinA vitamin A derivative used to treat acne vulgaris and certain types of promyelocytic leukemia, as well as various skin conditions in over-the-counter medications.
IsotretinoinA retinoid used to treat severe recalcitrant acne.
ClindamycinA lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria.
Benzoyl peroxideAn antibacterial and anti-inflammatory agent used for the symptomatic treatment of mild to moderate acne vulgaris and rosacea.
Aluminum chlorideIndicated for the control of minor hemorrhage during dental restorative procedures. Indicated to reduce underarm perspiration.
ResorcinolContemporary therapeutic uses for resorcinol primarily revolve around the use of the phenol derivative as an active ingredient in topical antiseptics [L2745, L2744, L40069, F61] or as topical antibacterial skin...
Aluminum oxideAluminum oxide has a chemical formula Al2O3. It is amphoteric in nature, and is used in various chemical, industrial and commercial applications. It is considered an indirect additive used in...
NadifloxacinA topical fluoroquinolone used in the treatment of acne and topical bacterial skin infections.
TioxoloneNot Annotated
MotretinideNot Annotated
Vitamin AA vitamin important for retinal function that is used clinically to correct vitamin A deficiency.
ErythromycinA macrolide antibiotic used to treat and prevent a variety of bacterial infections.
DapsoneA sulfone drug used to treat acne vulgaris, Hansen's disease, and dermatitis herpetiformis.
FluorometholoneAn ophthalmic corticosteroid used for the relief of inflammation located in both the palpebral and bulbar conjunctiva, the cornea, and the anterior segment of the globe of the eye.
ChloramphenicolA broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity.
MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
BithionolBithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the...
MesulfenNot Annotated
SarecyclineA tetracycline antibiotic used to treat inflammatory lesions of non-nodular moderate to severe acne vulgaris.
TrifaroteneA topical retinoid indicated for the treatment of acne vulgaris.
ClascoteroneAn androgen receptor antagonist used for the topical treatment of acne vulgaris in patients 12 years of age and older.
MinocyclineA tetracycline analog used to treat a wide variety of infections in the body.
Drugs & Drug Targets
MeclocyclineOuter membrane protein Ftransporter
MeclocyclineOuter membrane porin Ctransporter
Meclocycline30S ribosomal protein S7target
MeclocyclineTetX family tetracycline inactivation enzymeenzyme
AdapaleneRetinoic acid receptor betatarget
AdapaleneRetinoic acid receptor gammatarget
AdapaleneRetinoic acid receptor RXR-alphatarget
AdapaleneRetinoic acid receptor RXR-betatarget
AdapaleneRetinoic acid receptor RXR-gammatarget
AdapaleneTranscription factor AP-1target
AdapaleneRetinoic acid receptor alphatarget
AdapaleneAspartate aminotransferase, cytoplasmictarget
AdapaleneToll-like receptor 2target
Azelaic acid3-oxo-5-alpha-steroid 4-dehydrogenase 2target
Azelaic acidDNA polymerase Itarget
Azelaic acidThioredoxin reductasetarget
Azelaic acidTyrosinasetarget
Azelaic acid3-oxo-5-beta-steroid 4-dehydrogenasetarget
SulfacetamideDihydropteroate synthasetarget
SulfacetamideDihydropteroate synthase type-1target
SulfacetamideFolic acid synthesis protein FOL1target
TretinoinRetinoic acid receptor gammatarget
TretinoinRetinoic acid receptor RXR-betatarget
TretinoinRetinal dehydrogenase 1target
TretinoinRetinoic acid-induced protein 3target
TretinoinRetinoic acid receptor RXR-gammatarget
TretinoinRetinal dehydrogenase 2target
TretinoinRetinoic acid receptor responder protein 1target
TretinoinCytochrome P450 2C8enzyme
TretinoinCellular retinoic acid-binding protein 1transporter
TretinoinCellular retinoic acid-binding protein 2transporter
TretinoinCytochrome P450 2B6enzyme
TretinoinCytochrome P450 3A4enzyme
TretinoinCytochrome P450 3A5enzyme
TretinoinCytochrome P450 2A6enzyme
TretinoinCytochrome P450 3A7enzyme
TretinoinCytochrome P450 2C18enzyme
TretinoinCytochrome P450 2C9enzyme
TretinoinCytochrome P450 4A11enzyme
TretinoinCytochrome P450 1A1enzyme
TretinoinRetinoic acid receptor alphatarget
TretinoinRetinoic acid receptor betatarget
TretinoinOdorant-binding protein 2atarget
TretinoinRetinol-binding protein 4target
TretinoinSerum albumincarrier
Tretinoin[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrialtarget
TretinoinRetinoic acid receptor RXR-alphatarget
TretinoinCarcinoembryonic antigentarget
TretinoinUDP-glucuronosyltransferase 2B7enzyme
TretinoinCytochrome P450 2E1enzyme
TretinoinCytochrome P450 26A1enzyme
TretinoinCellular retinoic acid-binding protein 1target
IsotretinoinRetinoic acid receptor alphatarget
IsotretinoinSerum albumincarrier
IsotretinoinRetinoic acid receptor gammatarget
IsotretinoinCytochrome P450 3A4enzyme
ClindamycinCytochrome P450 3A4enzyme
ClindamycinCytochrome P450 3A5enzyme
ClindamycinAlpha-1-acid glycoprotein 1carrier
ClindamycinP-glycoprotein 1transporter
Clindamycin50S ribosomal protein L1target
Benzoyl peroxideCatalaseenzyme
Benzoyl peroxideCatalasetarget
Benzoyl peroxideArginine decarboxylasetarget
Benzoyl peroxideProtein kinase Ctarget
Benzoyl peroxideGlutathione peroxidasetarget
Benzoyl peroxideSuperoxide Dismutasestarget
Aluminum chlorideGlutamate dehydrogenase 1, mitochondrialtarget
ResorcinolThyroid peroxidasetarget
Vitamin ARetinol dehydrogenase 12target
Vitamin A11-cis retinol dehydrogenasetarget
Vitamin ARetinol dehydrogenase 13target
Vitamin ARetinol-binding protein 5carrier
Vitamin ARetinoid-binding protein 7carrier
Vitamin ARetinol-binding protein 4carrier
Vitamin ARetinol-binding protein 2carrier
Vitamin ARetinal dehydrogenase 2target
Vitamin ARetinal dehydrogenase 1target
Vitamin ALecithin retinol acyltransferasetarget
Vitamin AShort-chain dehydrogenase/reductase 3target
Vitamin AAldehyde dehydrogenase family 1 member A3target
Vitamin AAll-trans-retinol 13,14-reductasetarget
Vitamin ARetinol dehydrogenase 11target
Vitamin ADehydrogenase/reductase SDR family member 4target
Vitamin ARetinol dehydrogenase 14target
Vitamin ARetinol dehydrogenase 8target
Vitamin ACytochrome P450 26A1enzyme
Vitamin AApolipoprotein Dtarget
Vitamin AProstaglandin-H2 D-isomerasetarget
Vitamin ASerum albumincarrier
Vitamin ARetinaldehyde-binding protein 1carrier
Vitamin ARetinol-binding protein 3carrier
Vitamin ARetinol-binding protein 1carrier
Vitamin AReceptor for retinol uptake STRA6transporter
Erythromycin23S ribosomal RNAtarget
ErythromycinCytochrome P450 3A4enzyme
ErythromycinCytochrome P450 3A7enzyme
ErythromycinP-glycoprotein 1transporter
ErythromycinSolute carrier organic anion transporter family member 1B1transporter
ErythromycinMotilin receptortarget
ErythromycinPotassium voltage-gated channel subfamily H member 2target
ErythromycinCytochrome P450 3A5enzyme
ErythromycinSolute carrier organic anion transporter family member 1B3transporter
ErythromycinBile salt export pumptransporter
ErythromycinCanalicular multispecific organic anion transporter 1transporter
ErythromycinSolute carrier organic anion transporter family member 1A2transporter
DapsoneInactive dihydropteroate synthase 2target
DapsoneDihydropteroate synthase 1target
DapsoneCytochrome P450 2C9enzyme
DapsoneCytochrome P450 2E1enzyme
DapsoneCytochrome P450 3A4enzyme
DapsoneDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DapsoneProstaglandin G/H synthase 1enzyme
DapsoneProstaglandin G/H synthase 2enzyme
DapsoneCytochrome P450 2C8enzyme
DapsoneCytochrome P450 2C19enzyme
DapsoneArylamine N-acetyltransferase 2enzyme
DapsoneCytochrome P450 3A5enzyme
DapsoneCytochrome P450 3A7enzyme
DapsoneCytochrome P450 2C18enzyme
FluorometholoneCorticosteroid-binding globulincarrier
FluorometholoneCytochrome P450 3A4enzyme
FluorometholoneGlucocorticoid receptortarget
FluorometholoneCytochrome P450 3A5enzyme
ChloramphenicolComplement decay-accelerating factortarget
ChloramphenicolDr hemagglutinin structural subunittarget
ChloramphenicolCytochrome P450 2C19enzyme
ChloramphenicolCytochrome P450 3A4enzyme
ChloramphenicolCytochrome P450 3A5enzyme
ChloramphenicolCytochrome P450 3A7enzyme
ChloramphenicolSolute carrier family 22 member 6transporter
Chloramphenicol50S ribosomal protein L16target
ChloramphenicolChloramphenicol acetyltransferase 3enzyme
ChloramphenicolChloramphenicol acetyltransferaseenzyme
ChloramphenicolChloramphenicol 3-O phosphotransferaseenzyme
MethylprednisoloneGlucocorticoid receptortarget
MethylprednisoloneCytochrome P450 3A4enzyme
MethylprednisoloneP-glycoprotein 1transporter
MethylprednisoloneCytochrome P450 3A Subfamilyenzyme
MethylprednisoloneCytochrome P450 2A6enzyme
MethylprednisoloneCytochrome P450 1B1enzyme
MethylprednisoloneCytochrome P450 2B6enzyme
MethylprednisoloneCytochrome P450 2C8enzyme
MethylprednisoloneCytochrome P450 2C9enzyme
MethylprednisoloneCytochrome P450 2C19enzyme
MethylprednisoloneAnnexin A1target
Methylprednisolone20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)enzyme
Methylprednisolone11beta-hydroxysteroid dehydrogenaseenzyme
MethylprednisoloneSerum albumincarrier
DexamethasoneGlucocorticoid receptortarget
DexamethasoneAnnexin A1target
DexamethasoneNitric oxide synthase, inducibletarget
DexamethasoneNuclear receptor subfamily 0 group B member 1target
DexamethasoneCytochrome P450 3A4enzyme
DexamethasoneCytochrome P450 3A5enzyme
DexamethasoneCytochrome P450 3A7enzyme
DexamethasoneBile salt export pumptransporter
DexamethasoneP-glycoprotein 1transporter
DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DexamethasoneATP-binding cassette sub-family G member 2transporter
DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DexamethasoneCytochrome P450 1A1enzyme
DexamethasoneCytochrome P450 2A6enzyme
DexamethasoneCytochrome P450 2B6enzyme
DexamethasoneCytochrome P450 2C19enzyme
DexamethasoneCytochrome P450 2C8enzyme
DexamethasoneCytochrome P450 2E1enzyme
DexamethasoneCytochrome P450 3A43enzyme
DexamethasoneCytochrome P450 4A11enzyme
DexamethasoneNuclear receptor subfamily 1 group I member 2target
DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DexamethasoneSerum albumincarrier
DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DexamethasoneSolute carrier family 22 member 8transporter
SarecyclineP-glycoprotein 1transporter
TrifaroteneCytochrome P450 2C9enzyme
TrifaroteneCytochrome P450 3A4enzyme
TrifaroteneCytochrome P450 2C8enzyme
TrifaroteneCytochrome P450 2B6enzyme
TrifaroteneRetinoic acid receptor gammatarget
TrifaroteneRetinoic acid receptor alphatarget
TrifaroteneRetinoic acid receptor betatarget
ClascoteroneAndrogen receptortarget
ClascoteroneCytochrome P450 1A2enzyme
ClascoteroneCytochrome P450 2B6enzyme
ClascoteroneCytochrome P450 2C8enzyme
ClascoteroneCytochrome P450 2C9enzyme
ClascoteroneCytochrome P450 2C19enzyme
ClascoteroneCytochrome P450 2D6enzyme
ClascoteroneCytochrome P450 2E1enzyme
ClascoteroneCytochrome P450 3A4enzyme
Minocycline30S ribosomal protein S4target
Minocycline30S ribosomal protein S9target
Minocycline16S ribosomal RNAtarget
MinocyclineInterleukin-1 betatarget
MinocyclineArachidonate 5-lipoxygenasetarget
MinocyclineMatrix metalloproteinase-9target
MinocyclineVascular endothelial growth factor Atarget
MinocyclineCytochrome ctarget
MinocyclineSolute carrier family 22 member 6transporter
MinocyclineSolute carrier family 22 member 7transporter
MinocyclineOuter membrane protein Ftransporter
MinocyclineOuter membrane porin Ctransporter
MinocyclineMitogen-activated Protein Kinasestarget
MinocyclineNitric oxide synthase, inducibletarget