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Sulfanitran

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

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Identification

Generic Name
Sulfanitran
DrugBank Accession Number
DB11463
Background

Not Available

Type
Small Molecule
Groups
Vet approved
Structure
3D
Similar Structures
Weight
Average: 335.33
Monoisotopic: 335.057591705
Chemical Formula
C14H13N3O5S
Synonyms
  • Sulfanitran
External IDs
  • NSC-77120
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available
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Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
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interactions in your software
AcarboseThe therapeutic efficacy of Acarbose can be increased when used in combination with Sulfanitran.
AcetohexamideThe therapeutic efficacy of Acetohexamide can be increased when used in combination with Sulfanitran.
AlbiglutideThe therapeutic efficacy of Albiglutide can be increased when used in combination with Sulfanitran.
AlogliptinThe therapeutic efficacy of Alogliptin can be increased when used in combination with Sulfanitran.
BenzylpenicillinSulfanitran may decrease the excretion rate of Benzylpenicillin which could result in a higher serum level.
Food Interactions
Not Available

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as sulfanilides. These are organic aromatic compounds containing a sulfanilide moiety, with the general structure RS(=O)(=O)NC1=CC=CC=C1.
Kingdom
Organic compounds
Super Class
Benzenoids
Class
Benzene and substituted derivatives
Sub Class
Sulfanilides
Direct Parent
Sulfanilides
Alternative Parents
Benzenesulfonamides / Nitrobenzenes / Benzenesulfonyl compounds / Nitroaromatic compounds / Organosulfonamides / Aminosulfonyl compounds / Propargyl-type 1,3-dipolar organic compounds / Organic oxoazanium compounds / Carboximidic acids / Organopnictogen compounds
show 5 more
Substituents
Allyl-type 1,3-dipolar organic compound / Aminosulfonyl compound / Aromatic homomonocyclic compound / Benzenesulfonamide / Benzenesulfonyl group / C-nitro compound / Carboximidic acid / Carboximidic acid derivative / Hydrocarbon derivative / Nitroaromatic compound
show 18 more
Molecular Framework
Aromatic homomonocyclic compounds
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
QT35T5T35Q
CAS number
122-16-7
InChI Key
GWBPFRGXNGPPMF-UHFFFAOYSA-N
InChI
InChI=1S/C14H13N3O5S/c1-10(18)15-11-4-8-14(9-5-11)23(21,22)16-12-2-6-13(7-3-12)17(19)20/h2-9,16H,1H3,(H,15,18)
IUPAC Name
N-{4-[(4-nitrophenyl)sulfamoyl]phenyl}acetamide
SMILES
CC(=O)NC1=CC=C(C=C1)S(=O)(=O)NC1=CC=C(C=C1)[N+]([O-])=O

References

General References
  1. Authors unspecified: Determination of sulfanitran in animal feeds and pre-mixes. Analyst. 1977 Nov;102(1220):869-72. [Article]
  2. Zheng H, Wang P, Li J: [Determination of 12 sulfonamides in cosmetics by ultra performance liquid chromatography]. Se Pu. 2007 Mar;25(2):238-40. [Article]
  3. Zelcer N, Huisman MT, Reid G, Wielinga P, Breedveld P, Kuil A, Knipscheer P, Schellens JH, Schinkel AH, Borst P: Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2). J Biol Chem. 2003 Jun 27;278(26):23538-44. Epub 2003 Apr 17. [Article]
  4. Parks OW: Liquid chromatographic-electrochemical detection screening procedure for six nitro-containing drugs in chicken tissues at low ppb level. J Assoc Off Anal Chem. 1989 Jul-Aug;72(4):567-9. [Article]
  5. Ursic D, Berginc K, Zakelj S, Kristl A: Influence of luminal monosaccharides on secretion of glutathione conjugates from rat small intestine in vitro. Int J Pharm. 2009 Nov 3;381(2):199-204. doi: 10.1016/j.ijpharm.2009.03.011. Epub 2009 Mar 19. [Article]
  6. Cai Z, Zhang Y, Pan H, Tie X, Ren Y: Simultaneous determination of 24 sulfonamide residues in meat by ultra-performance liquid chromatography tandem mass spectrometry. J Chromatogr A. 2008 Jul 25;1200(2):144-55. doi: 10.1016/j.chroma.2008.05.095. Epub 2008 Jun 8. [Article]
  7. Zimmermann C, van de Wetering K, van de Steeg E, Wagenaar E, Vens C, Schinkel AH: Species-dependent transport and modulation properties of human and mouse multidrug resistance protein 2 (MRP2/Mrp2, ABCC2/Abcc2). Drug Metab Dispos. 2008 Apr;36(4):631-40. doi: 10.1124/dmd.107.019620. Epub 2008 Jan 7. [Article]
  8. Eaves KL, Colvin BM, Hanks AR, Bushway RJ: High pressure liquid chromatographic determination of sulfanitran and dinsed in medicated feeds and premixes. J Assoc Off Anal Chem. 1977 Sep;60(5):1064-6. [Article]
KEGG Drug
D05951
ChemSpider
5143
ChEBI
114204
ChEMBL
CHEMBL493636
ZINC
ZINC000003873374
Wikipedia
Sulfanitran

Clinical Trials

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Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.0343 mg/mLALOGPS
logP1.9ALOGPS
logP1.64Chemaxon
logS-4ALOGPS
pKa (Strongest Acidic)7.44Chemaxon
pKa (Strongest Basic)-4.4Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count5Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area118.41 Å2Chemaxon
Rotatable Bond Count4Chemaxon
Refractivity84.07 m3·mol-1Chemaxon
Polarizability31.2 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-198.2723491
predicted
DarkChem Lite v0.1.0
[M-H]-170.41176
predicted
DeepCCS 1.0 (2019)
[M+H]+198.1549491
predicted
DarkChem Lite v0.1.0
[M+H]+172.76976
predicted
DeepCCS 1.0 (2019)
[M+Na]+197.9582491
predicted
DarkChem Lite v0.1.0
[M+Na]+179.07909
predicted
DeepCCS 1.0 (2019)

Drug created at February 25, 2016 18:57 / Updated at February 21, 2021 18:53