Variola Major (Smallpox)

Also known as: Smallpox / (Viral exanthemata [& variants]) or (orf) or (milkers node) / Smallpox (disorder) / Variola major (disorder) / Smallpox NOS (disorder) / Smallpox, unspecified

DrugDrug NameDrug Description
DB12151BrincidofovirAn oral lipid prodrug of cidofovir used in the treatment of human smallpox disease.
DB00369CidofovirAn antiviral agent used to treat Cytomegalovirus (CMV) retinitis in patients with AIDS.
DB15483Modified vaccinia ankaraA live, non-replicating orthopoxvirus vaccine used to prevent smallpox, monkeypox, and other diseases caused by vaccinia virus.
DB14711Smallpox (Vaccinia) Vaccine, LiveThe live antigen of the New York City Board of Health strain of Vaccinia is indicated (within the ACAM2000 formulation) for active immunization against smallpox disease in patients determined to...
DB12020TecovirimatAn antiviral medication used to treat smallpox, monkeypox, and cowpox.
DrugDrug NameTargetType
DB12151BrincidofovirLeukotriene-B(4) omega-hydroxylase 1enzyme
DB12151BrincidofovirSphingomyelin phosphodiesteraseenzyme
DB12151BrincidofovirDNA polymerasetarget
DB12151BrincidofovirCytochrome P450 1A2enzyme
DB12151BrincidofovirCytochrome P450 2B6enzyme
DB12151BrincidofovirCytochrome P450 2C8enzyme
DB12151BrincidofovirCytochrome P450 2C9enzyme
DB12151BrincidofovirCytochrome P450 2C19enzyme
DB12151BrincidofovirCytochrome P450 2D6enzyme
DB12151BrincidofovirATP-binding cassette sub-family G member 2transporter
DB12151BrincidofovirCanalicular multispecific organic anion transporter 1transporter
DB12151BrincidofovirBile salt export pumptransporter
DB12151BrincidofovirSolute carrier organic anion transporter family member 1B1transporter
DB12151BrincidofovirSolute carrier family 22 member 6transporter
DB12151BrincidofovirSolute carrier family 22 member 8transporter
DB12151BrincidofovirSolute carrier organic anion transporter family member 1B3transporter
DB12151BrincidofovirVariola virus DNAtarget
DB00369CidofovirDNA polymerase catalytic subunittarget
DB00369CidofovirSolute carrier family 22 member 6transporter
DB00369CidofovirThymidine phosphorylaseenzyme
DB12020TecovirimatEnvelope protein F13target
DB12020TecovirimatUDP-glucuronosyltransferase 1-1enzyme
DB12020TecovirimatUDP-glucuronosyltransferase 1-4enzyme
DB12020TecovirimatCytochrome P450 3A4enzyme
DB12020TecovirimatCytochrome P450 2C8enzyme
DB12020TecovirimatCytochrome P450 2C19enzyme
DB12020TecovirimatUDP-glucuronosyltransferase 1-3enzyme
DB12020TecovirimatATP-binding cassette sub-family G member 2transporter
DB12020TecovirimatCytochrome P450 2B6enzyme