Haemorrhoids

Also known as: Piles / Hemorrhoid / Hemorrhoids / Hemorrhoids (disorder) / Haemorrhoid / Hemorrhoids and perianal venous thrombosis / Hemorrhoids NOS (disorder) / Haemorrhoids NOS

DrugDrug NameDrug Description
DB15679Aluminum subacetateA medication used to prevent infection and treat irritation around the rectum.
DB11482Balsam of PeruBalsam of Peru is found in diverse cosmetics and perfumes as well as a flavoring agent in cough syrups, lozenges, chewing gum, and candies. As a medical agent, balsam of...
DB11105BenzalkoniumAn antiseptic agent used as a preservative in medications or as a disinfectant in cleaning products.
DB01086BenzocaineA topical local anesthetic used for the temporary relief of pain and itching associated with minor burns, sunburn, scrapes and insect bites or minor skin irritations.
DB15929Bismuth oxideNot Annotated
DB13909Bismuth subgallateA medication used to deodorize flatulence and stools as well as hemostasis in soft tissue surgery.
DB13346BufexamacAn NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses.
DB06724Calcium carbonateAn ionic compound used as a calcium supplement or antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach.
DB00527CinchocaineAn anesthetic used for local or regional anesthesia.
DB08995DiosminA citrus flavonoid medication used to support vascular health.
DB13529Dobesilic acidA medication indicated in the treatment of hemorrhoids, venous insufficiency, and other microangiopathies.
DB11594DomiphenAnti-infective (topical), it is used for the treatment of Acute Infectious Dental Diseases and other conditions.
DB13155EsculinAs medication, esculin is sometimes used as a vasoprotective agent. Esculin is also used in a microbiology laboratory to aid in the identification of bacterial species (especially Enterococci and Listeria),...
DB15821Fluocortolone caproateA corticosteroid indicated in the treatment of hemorrhoids, anal fissures, and corticosteroid-responsive dermatoses.
DB15777Fluocortolone pivalateA corticosteroid used to treat corticosteroid-responsive dermatoses and hemorrhoids.
DB11578Hard fatNot Annotated
DB01109HeparinAn anticoagulant indicated for thromboprophylaxis and to treat thrombosis associated with a variety of conditions such as pulmonary embolism and atrial fibrillation.
DB13195Horse chestnutA plant extract indicated in the treatment of venous insufficiency and other disorders caused by poor circulation.
DB00741HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
DB14539Hydrocortisone acetateA corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses and ulcerative colitis.
DB00825LevomentholAn organic compound used to treat mild to moderate muscle and joint pain.
DB00281LidocaineA local anesthetic used in a wide variety of superficial and invasive procedures.
DB13680NaftazoneA naphthoquinone derivative indicated in the treatment of varicose veins, hemorrhoids, and superficial thrombophlebitis.
DB12532OxetacaineAn antacid used to treat gastritis, peptic ulcer disease, heartburn, esophagitis, hiatus hernia, and anorexia.
DB00388PhenylephrineAn alpha-1 adrenergic agonist used in the management of hypotension, generally in the surgical setting associated with the use of anesthetics.
DB09268Picosulfuric acidA stimulant laxative used for cleansing of the colon as a preparation for colonoscopy in adults.
DB09345PramocaineA local anesthetic and antipruritic agent found in various topical preparations.
DB15999Prednisolone caproateA corticosteroid indicated to treat hemorrhoids, anal fissures, and proctitis.
DB15830RuscogeninAn anti-inflammatory steroid used in combination with local anesthetics for the treatment of hemorrhoids and for local anesthesia.
DB11365SennosidesA laxative used to treat constipation.
DB16556SpermacetiA lubricant used in medications to treat constipation associated with hemorrhoids.
DB09085TetracaineA local anaesthetic agent used to induce local analgesia in the eyes and skin during medical procedures.
DB00620TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
DB13227TribenosideAn anti-inflammatory agent that reduces vascular permeability and causes vasoconstriction to treat internal and external hemorrhoids.
DB13124TroxerutinTroxerutin has been used in trials studying the treatment of Chronic Venous Insufficiency.
DB11017YeastAn extract from Yeast used in allergy testing.
DrugDrug NameTargetType
DB01086BenzocaineSodium channel protein type 10 subunit alphatarget
DB01086BenzocaineP-glycoprotein 1transporter
DB01086BenzocaineLiver carboxylesterase 1enzyme
DB01086BenzocaineCytochrome P450 1A2enzyme
DB01086BenzocaineCytochrome P450 2B6enzyme
DB01086BenzocaineCytochrome P450 2C19enzyme
DB01086BenzocaineCytochrome P450 2D6enzyme
DB01086BenzocaineCytochrome P450 2E1enzyme
DB01086BenzocaineSerum albumincarrier
DB01086Benzocainealpha1-acid glycoproteincarrier
DB13909Bismuth subgallateSerum albumincarrier
DB13346BufexamacProstaglandin G/H synthase 1target
DB13346BufexamacProstaglandin G/H synthase 2target
DB13346BufexamacHistone deacetylase 6target
DB13346BufexamacHistone deacetylase 10target
DB00527CinchocaineSodium channel protein type 5 subunit alphatarget
DB00527CinchocaineSodium channel protein type 10 subunit alphatarget
DB00527CinchocaineCalmodulintarget
DB00527CinchocaineCholinesteraseenzyme
DB08995DiosminAryl hydrocarbon receptortarget
DB08995DiosminSerum albumincarrier
DB08995DiosminP-glycoprotein 1transporter
DB08995DiosminSolute carrier organic anion transporter family member 1B1transporter
DB08995DiosminSolute carrier organic anion transporter family member 1B3transporter
DB08995DiosminSolute carrier organic anion transporter family member 2B1transporter
DB08995DiosminCytochrome P450 1A1enzyme
DB08995DiosminCytochrome P450 2C9enzyme
DB08995DiosminCytochrome P450 2E1enzyme
DB08995DiosminCytochrome P450 3A4enzyme
DB13155EsculinGlutaminase kidney isoform, mitochondrialenzyme
DB13155EsculinAndrogen receptortarget
DB01109HeparinAntithrombin-IIItarget
DB01109HeparinCoagulation factor Xtarget
DB01109HeparinP-selectintarget
DB01109HeparinHeparanaseenzyme
DB01109HeparinFibroblast growth factor receptor 4target
DB01109HeparinFibroblast growth factor 4target
DB01109HeparinFibroblast growth factor 19target
DB01109HeparinFibroblast growth factor receptor 1target
DB01109HeparinFibroblast growth factor 1target
DB01109HeparinFibroblast growth factor receptor 2target
DB01109HeparinFibroblast growth factor 2target
DB01109HeparinPlatelet factor 4target
DB01109HeparinHepatocyte growth factortarget
DB01109HeparinThyroxine-binding globulincarrier
DB00741HydrocortisoneAnnexin A1target
DB00741HydrocortisoneGlucocorticoid receptortarget
DB00741HydrocortisoneSex hormone-binding globulincarrier
DB00741HydrocortisoneCytochrome P450 3A4enzyme
DB00741HydrocortisoneCytochrome P450 3A5enzyme
DB00741HydrocortisoneCytochrome P450 3A7enzyme
DB00741HydrocortisoneP-glycoprotein 1transporter
DB00741HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
DB00741HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 2C8enzyme
DB00741HydrocortisoneCorticosteroid-binding globulincarrier
DB00741HydrocortisoneSolute carrier family 22 member 8transporter
DB00741Hydrocortisone3-oxo-5-beta-steroid 4-dehydrogenaseenzyme
DB00741Hydrocortisone3-oxo-5-alpha-steroid 4-dehydrogenase 2enzyme
DB00741HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DB00741HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB00741HydrocortisoneCytochrome P450 2A6enzyme
DB00741HydrocortisoneCytochrome P450 1B1enzyme
DB00741HydrocortisoneCytochrome P450 2B6enzyme
DB00741HydrocortisoneCytochrome P450 2C9enzyme
DB00741HydrocortisoneCytochrome P450 2C19enzyme
DB14539Hydrocortisone acetateAnnexin A1target
DB14539Hydrocortisone acetateGlucocorticoid receptortarget
DB14539Hydrocortisone acetateSex hormone-binding globulincarrier
DB14539Hydrocortisone acetateCytochrome P450 3A4enzyme
DB14539Hydrocortisone acetateCytochrome P450 3A5enzyme
DB14539Hydrocortisone acetateCytochrome P450 3A7enzyme
DB14539Hydrocortisone acetateP-glycoprotein 1transporter
DB14539Hydrocortisone acetateSolute carrier organic anion transporter family member 1A2transporter
DB14539Hydrocortisone acetateATP-binding cassette sub-family G member 2transporter
DB14539Hydrocortisone acetateCytochrome P450 11B1, mitochondrialenzyme
DB14539Hydrocortisone acetateCytochrome P450 11B2, mitochondrialenzyme
DB14539Hydrocortisone acetateCytochrome P450 2C8enzyme
DB14539Hydrocortisone acetateCorticosteroid-binding globulincarrier
DB14539Hydrocortisone acetateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14539Hydrocortisone acetate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14539Hydrocortisone acetateSolute carrier family 22 member 8transporter
DB00825LevomentholTransient receptor potential cation channel subfamily A member 1target
DB00825LevomentholTransient receptor potential cation channel subfamily M member 8target
DB00825LevomentholTransient receptor potential cation channel subfamily V member 3target
DB00825LevomentholKappa-type opioid receptortarget
DB00825LevomentholVoltage-dependent L-type calcium channeltarget
DB00825LevomentholCytochrome P450 3A4enzyme
DB00281LidocaineSodium channel protein type 5 subunit alphatarget
DB00281LidocaineSodium channel protein type 10 subunit alphatarget
DB00281LidocaineEpidermal growth factor receptortarget
DB00281LidocaineSodium channel protein type 9 subunit alphatarget
DB00281LidocaineCytochrome P450 1A2enzyme
DB00281LidocaineCytochrome P450 2D6enzyme
DB00281LidocaineCytochrome P450 3A4enzyme
DB00281LidocaineCytochrome P450 3A5enzyme
DB00281LidocaineCytochrome P450 3A7enzyme
DB00281LidocaineSolute carrier family 22 member 5transporter
DB00281LidocaineP-glycoprotein 1transporter
DB00281LidocaineCytochrome P450 2A6enzyme
DB00281LidocaineCytochrome P450 2B6enzyme
DB00281LidocaineCytochrome P450 2C8enzyme
DB00281LidocaineCytochrome P450 2C9enzyme
DB00281LidocaineSodium channel protein type 4 subunit alphatarget
DB00281LidocaineAlpha-1-acid glycoprotein 1target
DB00281LidocaineAlpha-1-acid glycoprotein 2target
DB12532OxetacaineCytochrome P450 3A4enzyme
DB12532OxetacaineGastrintarget
DB00388PhenylephrineAlpha-1A adrenergic receptortarget
DB00388PhenylephrineAlpha-1B adrenergic receptortarget
DB00388PhenylephrineAmine oxidase [flavin-containing] Aenzyme
DB00388PhenylephrineAlpha-1D adrenergic receptortarget
DB00388PhenylephrineCytochrome P450 1A2enzyme
DB00388PhenylephrineSulfotransferase 1A3/1A4enzyme
DB00388PhenylephrineAmine oxidase [flavin-containing] Benzyme
DB09268Picosulfuric acidArylsulfate sulfotransferaseenzyme
DB09345PramocaineVoltage-gated sodium channel alpha subunittarget
DB11365SennosidesReverse transcriptase/RNaseHtarget
DB11365SennosidesAquaporin-3target
DB09085TetracaineRyanodine receptor 1target
DB09085TetracaineRyanodine receptor 2target
DB09085TetracaineVoltage-gated sodium channel alpha subunittarget
DB00620TriamcinoloneCorticosteroid-binding globulincarrier
DB00620TriamcinoloneGlucocorticoid receptortarget
DB00620TriamcinoloneCytochrome P450 3A4enzyme
DB00620TriamcinoloneProstaglandin G/H synthase 2enzyme
DB00620TriamcinoloneCholinesteraseenzyme
DB00620TriamcinoloneCytochrome P450 3A5enzyme
DB00620TriamcinoloneCytochrome P450 3A7enzyme
DB00620TriamcinoloneSerum albumincarrier
DrugDrug NamePhaseStatusCount
DB00297Bupivacaine0Unknown Status1
DB01221Ketamine0Unknown Status1
DB00281Lidocaine1Completed1
DB00878Chlorhexidine2Completed1
DB14539Hydrocortisone acetate2Completed1
DB11686Iferanserin2Completed1
DB00281Lidocaine2Completed2
DB11105Benzalkonium2 / 3Unknown Status1
DB00343Diltiazem2 / 3Recruiting1
DB00281Lidocaine2 / 3Recruiting1
DB00281Lidocaine2 / 3Unknown Status1
DB00916Metronidazole2 / 3Recruiting1
DB06811Polidocanol2 / 3Completed1
DB00297Bupivacaine3Completed2
DB08995Diosmin3Unknown Status1
DB00668Epinephrine3Completed1
DB00281Lidocaine3Completed1
DB00916Metronidazole3Completed1
DB00750Prilocaine3Completed1
DB00297Bupivacaine4Completed1
DB00297Bupivacaine4Terminated1
DB00586Diclofenac4Completed1
DB00668Epinephrine4Terminated1
DB00813Fentanyl4Completed1
DB01221Ketamine4Completed1
DB01221Ketamine4Recruiting1
DB00581Lactulose4Terminated1
DB00281Lidocaine4Completed1
DB00916Metronidazole4Completed1
DB00750Prilocaine4Completed1
DB00316AcetaminophenNot AvailableCompleted1
DB00572AtropineNot AvailableUnknown Status1
DB00297BupivacaineNot AvailableCompleted1
DB01114ChlorpheniramineNot AvailableCompleted1
DB01234DexamethasoneNot AvailableCompleted1
DB08995DiosminNot AvailableCompleted1
DB00996GabapentinNot AvailableCompleted1
DB00741HydrocortisoneNot AvailableCompleted1
DB14539Hydrocortisone acetateNot AvailableCompleted1
DB01221KetamineNot AvailableCompleted1
DB00916MetronidazoleNot AvailableCompleted1
DB00388PhenylephrineNot AvailableCompleted1
DB09345PramocaineNot AvailableCompleted1
DB09089TrimebutineNot AvailableSuspended1