Reaction: Tamoxifen to 1 product

N-dealkylationMajor circulating metaboliteMetabolism of Tamoxifen

Tamoxifen is converted to N-Desmethyltamoxifen by Cytochrome P450 2D6, Cytochrome P450 1A1, Cytochrome P450 1A2 and 5 other enzymes.

Direction

What you can answer from here — as of August 02, 2019

8EnzymesEach linked to its target card
Listed above
6ReferencesThe literature this reaction is curated from
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Which other drugs are metabolised by Cytochrome P450 2D6, Cytochrome P450 1A1, and Cytochrome P450 1A2, and which of those pairings are clinically significant?

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