Reaction: Amitriptyline to 1 product
N-demethylationMetabolism of Amitriptyline
Amitriptyline is converted to Nortriptyline by Cytochrome P450 2C9, Cytochrome P450 2C19, Cytochrome P450 1A2 and 4 other enzymes.
- Reaction
- Direction
- Not Available
- Activity
- active
What you can answer from here — as of February 20, 2019
7EnzymesEach linked to its target cardListed above
Which other drugs are metabolised by Cytochrome P450 2C9, Cytochrome P450 2C19, and Cytochrome P450 1A2, and which of those pairings are clinically significant?
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