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Sodium- and chloride-dependent betaine transporter
go.drugbank.com/bio_entities/BE0004777TargetTransporterHumansTransporter that mediates cellular uptake of betaine and GABA in a sodium- and chloride-dependent process (PubMed:7589472). … Probably also involved in renal and hepatic osmotic regulation (By similarity)
Polypeptides: Sodium- and chloride-dependent betaine transporterHyaluronan and proteoglycan link protein 1
go.drugbank.com/bio_entities/BE0004933TargetHumansStabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix
Polypeptides: Hyaluronan and proteoglycan link protein 1Hyaluronan and proteoglycan link protein 3
go.drugbank.com/bio_entities/BE0004935TargetHumansMay function in hyaluronic acid binding
Polypeptides: Hyaluronan and proteoglycan link protein 3Multidrug and toxin extrusion protein 2
go.drugbank.com/bio_entities/BE0004752TransporterHumansMediates the efflux of endogenous compounds such as, creatinine, thiamine and estrone-3-sulfate. … Plays a physiological role in the excretion of drugs, toxins and endogenous metabolites through the kidney
Polypeptides: Multidrug and toxin extrusion protein 2Nucleolar and coiled-body phosphoprotein 1
go.drugbank.com/bio_entities/BE0005819TargetHumansIt has intrinsic GTPase and ATPase activities (PubMed:9016786) … processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification (PubMed:26399832).
Polypeptides: Nucleolar and coiled-body phosphoprotein 1Cysteine and glycine-rich protein 1
go.drugbank.com/bio_entities/BE0009098TargetHumansCould play a role in neuronal development
Polypeptides: Cysteine and glycine-rich protein 1Sodium- and chloride-dependent taurine transporter
go.drugbank.com/bio_entities/BE0009148TransporterHumansTaurine acts as an anti-aging agent by reducing cellular senescence and combating oxidative stress: levels decline with age and supplementation has been shown to extend lifespan (By similarity). … Can also mediate transport of beta-alanine, hypotaurine and gamma-aminobutyric acid (GABA) (PubMed:39837997, PubMed:40108165, PubMed:40789850, PubMed:41269860, PubMed:8010975)
Polypeptides: Sodium- and chloride-dependent taurine transporterTRAF2 and NCK-interacting protein kinase
go.drugbank.com/bio_entities/BE0009399TargetHumansMAP4Ks act in parallel to and are partially redundant with STK3/MST2 and STK4/MST2 in the phosphorylation and activation of LATS1/2, and establish MAP4Ks as components of the expanded Hippo pathway (PubMed … Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development.
Polypeptides: TRAF2 and NCK-interacting protein kinaseSodium- and chloride-dependent GABA transporter 1
go.drugbank.com/bio_entities/BE0000249TargetHumans+), Cl(-) and GABA (By similarity). … The direction and magnitude of GABA transport is a consequence of the prevailing thermodynamic conditions, determined by membrane potential and the intracellular and extracellular concentrations of Na(
Polypeptides: Sodium- and chloride-dependent GABA transporter 1Sodium- and chloride-dependent creatine transporter 1
go.drugbank.com/bio_entities/BE0000375TargetTransporterHumansPlays an important role in supplying creatine to the brain via the blood-brain barrier (By similarity)
Polypeptides: Sodium- and chloride-dependent creatine transporter 1