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Alprazolam Action Pathway
smpdb.ca/view/SMP0125056Drug actionAlprazolam is a triazolobenzodiazepine with intermediate onset commonly used to treat panic disorders and generalized anxiety in addition to anxiety associated with depression. Alprazolam is also indicated, either as a standard or extend...
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Ethanol GABA Agonist Action Pathway
smpdb.ca/view/SMP0125151Drug actionEthanol, commonly seen in the form of various alcohols as well as hand sanitizer, is a drug that is injected intrathecally. Ethanol's effects are mainly seen in the brain where it binds to many receptors. The main effects are seen by the...
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Butabarbital Action Pathway
smpdb.ca/view/SMP0126119Drug actionButabarbital is a barbiturate drug used as a sedative and hypnotic. Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates. This makes butabarbital a useful drug for treating se...
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Butabarbital · Calcium · Magnesium cation +3 moreEnzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Etomidate Action Pathway
smpdb.ca/view/SMP0126127Drug actionEtomidate is a short-acting intravenous anesthetic indicated for the induction of anesthesia and supplementation of subpotent anesthesia during short operative procedures. Imidazole derivative anesthetic and hypnotic with little effect o...
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Eszopiclone Action Pathway
smpdb.ca/view/SMP0126150Drug actionEszopiclone is a sedative-hypnotic used in the treatment of insomnia, improving both the latency phase and the maintenance phase of sleep. Eszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine hypnotic dr...
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Methylphenobarbital Action Pathway
smpdb.ca/view/SMP0126819Drug actionMephobarbital, a barbiturate, undergoes metabolism into phenobarbital and has been employed for similar purposes, particularly in managing epilepsy; however, there exists no evidence supporting its superiority over phenobarbital. It serv...
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Methylphenobarbital · Calcium · Magnesium cation +3 moreEnzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Quinidine barbiturate Action Pathway
smpdb.ca/view/SMP0126833Drug actionThe administration of quinidine derivatives is utilized to monitor various skin and mucosal reactions. In certain cases, a papulopurpuric eruption can arise in patients (without thrombocytopenia) who are intermittently taking quinidine p...
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Quinidine barbiturate · Calcium · Magnesium cation +3 moreEnzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Butobarbital Action Pathway
smpdb.ca/view/SMP0126835Drug actionButobarbital, also known as butethal or butobarbitone, functions as both a sedative and a hypnotic drug, primarily intended for treating insomnia. Belonging to the barbiturate group of medicines, it is presumed to act on GABA receptors i...
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Butobarbital · Calcium · Magnesium cation +3 moreEnzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Methylenetetrahydrofolate Reductase Deficiency (MTHFRD)
smpdb.ca/view/SMP0000543DiseaseMethylenetetrahydrofolate reductase deficiency (MTHFRD; Homocystinuria due to defect of n(5,10)-methylene THF deficiency) is caused by a defect in the MTHFR gene which codes for methylenetetrahydrofolate reductase. Methylenetetrahydrofol...
Argininosuccinic Aciduria
smpdb.ca/view/SMP0125766DiseaseIt results in accumulation of citrulline, arginosuccinic acid, L-arginine, and L-glutamic acid in plasma as well as ammonia in blood. Infants are lethargic and unwilling to eat. … Argininosuccinic Aciduria, (Argininosuccinase Deficiency, Argininosuccinate Lyase Deficiency, ASL Deficiency) is an autosomal recessive disorder caused by a mutation in the ASL gene which codes for argininosuccinate
Drugs: Pyridoxal phosphate · Pyruvic acid · Arginine · Aspartic acid · Ornithine · L-Glutamine +11 moreEnzymes: Y+L amino acid transporter 1, Neutral amino acid transporter A