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Displaying results 91 - 100 of 7187 in total
  1. Target

    Protein kinase C beta type

    go.drugbank.com/bio_entities/BE0000872
    TargetHumans

    Phosphorylates and activates LRRK1, which phosphorylates RAB proteins involved in intracellular trafficking (PubMed:36040231). … Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative

    Polypeptides: Protein kinase C beta type
  2. Target

    Protein kinase C alpha type

    go.drugbank.com/bio_entities/BE0001132
    TargetHumans

    synthesis, protein-DNA ratio and cell surface area. … Phosphorylates and activates LRRK1, which phosphorylates RAB proteins involved in intracellular trafficking (PubMed:36040231).

    Polypeptides: Protein kinase C alpha type
  3. Drug

    Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine

    go.drugbank.com/drugs/DB10061
    ApprovedInvestigational

    diphtheriae_ CRM197 protein carrier, resulting in four drug substances contained in each dose of vaccine. … [A253277] Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine contains serogroup A, C, Y, and W-135 oligosaccharides conjugated individually to _Corynebacterium

    Synonyms: Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine
  4. Target

    Myosin-binding protein C, cardiac-type

    go.drugbank.com/bio_entities/BE0014590
    TargetHumans

    Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands.

    Polypeptides: Myosin-binding protein C, cardiac-typeSynonyms: C-protein, cardiac muscle isoform, Cardiac MyBP-C
  5. Target

    Ubiquitin-conjugating enzyme E2 C

    go.drugbank.com/bio_entities/BE0010756
    TargetHumans

    Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. … Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit

    Polypeptides: Ubiquitin-conjugating enzyme E2 CSynonyms: Ubiquitin-protein ligase C, Ubiquitin carrier protein C
  6. Target

    Receptor-type tyrosine-protein phosphatase C

    go.drugbank.com/bio_entities/BE0010406
    TargetHumans

    Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor (PubMed:35767951). Acts as a positive regulator of T-cell coactivation upon binding to DPP4.

    Polypeptides: Receptor-type tyrosine-protein phosphatase C
  7. Target

    Outer membrane porin C

    go.drugbank.com/bio_entities/BE0009852
    TransporterEscherichia coli (strain K12)

    Forms pores that allow passive diffusion of small molecules across the outer membrane.

    Polypeptides: Outer membrane porin CSynonyms: Outer membrane protein C, Outer membrane protein 1B
  8. Drug

    Dazodalibep

    go.drugbank.com/drugs/DB19025
    Investigational

    Dazodalibep is under investigation in clinical trial NCT06104124 (A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic

    Synonyms: PROTEIN VIB4920 (RECOMBINANT HUMAN TENASCIN C CD40 LIGAND-BINDING THIRD FIBRONECTIN TYPE III DOMAIN) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 19-AMINO ACID LINKER) FUSION PROTEIN WITH TENASCIN C CD40 LIGAND-BINDING
  9. Target

    Myristoylated alanine-rich C-kinase substrate

    go.drugbank.com/bio_entities/BE0012891
    TargetHumans

    protein docking to membranes (PubMed:23704996, PubMed:36009319). … Sequesters phosphatidylinositol 4,5-bisphosphate (PIP2) at lipid rafts in the plasma membrane of quiescent cells, an action reversed by protein kinase C, ultimately inhibiting exocytosis (PubMed:23704996

    Polypeptides: Myristoylated alanine-rich C-kinase substrateSynonyms: Protein kinase C substrate, 80 kDa protein, light chain, 80K-L protein
  10. Drug

    Haemophilus influenzae b polysaccharide-tetanus conjugate

    go.drugbank.com/drugs/DB15876
    ApprovedInvestigational

    Synonyms: Haemophilus influenzae type b polysaccharide conjugated to tetanus protein, Haemophilus influenzae type b polysaccharide conjugated to the tetanus proteinProducts: LANTIGEN B