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Lamivudine
go.drugbank.com/drugs/DB00709ApprovedInvestigationalA reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
Mixtures: Triumeq PD, ABACAVIR E LAMIVUDINA DOC GENERICICategories: P-glycoprotein substratesTimolol
go.drugbank.com/drugs/DB00373ApprovedInvestigationalTimolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. It is also used in tablet form as a drug to treat hypertension. Timolol was first approved by the...
Mixtures: Cosopt PF, Cosopt PFCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesNitroglycerin
go.drugbank.com/drugs/DB00727ApprovedInvestigationalNitroglycerin, also known as glyceryl trinitrate, is an organic nitrate and a vasodilating agent that was first discovered in 1847. Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced ...
Products: NITROGLICERINA PH&T, NITROGLICERINA DOC GENERICICarboxymethylcellulose
go.drugbank.com/drugs/DB11059ApprovedInvestigationalCarboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups. It is added in food products as a viscosity modifier or t...
Mixtures: Refresh Digital PF, Refresh RELIEVA PFProducts: FREEGEN PFMethylphenidate
go.drugbank.com/drugs/DB00422ApprovedInvestigationalA177541] There is a dose-related effect of psychostimulants on receptor stimulation, where higher doses are shown to increase norepinephrine (NE) and dopamine (DA) efflux throughout the brain which can result
Products: Jornay PM, JORNAY PM Extended-ReleaseUrea
go.drugbank.com/drugs/DB03904ApprovedInvestigationalA compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
Products: Umecta PD UreaIpsapirone
go.drugbank.com/drugs/DB20133ExperimentalThe usage of the INN stem '-pirone' in the name indicates that Ipsapirone is a anxiolytic, buspirone derivative. Ipsapirone has a monoisotopic molecular weight of 401.15 Da.
Tislelizumab
go.drugbank.com/drugs/DB14922ApprovedInvestigational[A262909] By blocking PD-L1/PD-L2–mediated cell signaling, tislelizumab restores T-cell function through cytokine production, resulting in immune-mediated antitumor responses. … Tislelizumab is a humanized monoclonal IgG4 antibody against programmed death receptor-1 (PD-1).
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitorsEfanesoctocog alfa
go.drugbank.com/drugs/DB16662ApprovedInvestigationalTo extend the half-life of FVIII, efanesoctocog alfa is fused to dimeric Fc, a D'D3 domain of VWF, and two XTEN polypeptides.
Synonyms: Antihemophilic factor (recombinant), Fc-VWF-XTEN fusion protein-ehtlAtezolizumab
go.drugbank.com/drugs/DB11595ApprovedInvestigationalAtezolizumab is a humanized monoclonal antibody used to prevent the interaction of PD-L1 and PD-1, removing inhibition of immune responses seen in some cancers. … The rest of atezolizumab indications remain unaffected.[L44246]
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors