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Displaying results 1001 - 1010 of 10000 in total
  1. Pathway

    Oxprenolol B2-Adrenergic Vasoconstriction Action Pathway

    smpdb.ca/view/SMP0126584
    Drug action

    Oxprenolol is a non-selective beta-adrenergic antagonist used to treat hypertension, angina pectoris, arrhythmias, and anxiety. Oxprenolol is a non-selective beta blocker with some intrinsic sympathomimetic activity. Oxprenolol is a lipo...

    Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Oxprenolol · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  2. Pathway

    Pindolol B2-Adrenergic Vasodilation Action Pathway

    smpdb.ca/view/SMP0126653
    Drug action

    Pindolol is a beta adrenoceptor antagonist and partial agonist used to treat hypertension, edema, ventricular tachycardias, and atrial fibrillation. It can be found under the bran names Viskazide and Visken and is administered as an oral...

    Drugs: ATP · Pindolol · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  3. Pathway

    Acetaminophen Metabolism Pathway

    smpdb.ca/view/SMP0000640
    Drug metabolism

    Acetaminophen (APAP) is metabolized primarily in the liver. Glucuronidation is the main route, accounting for 45-55% of APAP metabolism, and is mediatied by UGT1A1, UGT1A6, UGT1A9, UGT2B15 in the liver and UGT1A10 in the gut. APAP can al...

    Drugs: Glutathione · NADH · ATP · Acetaminophen · Mesoheme · Uridine-5'-Diphosphate
    Enzymes: Glutathione S-transferase P, Glutathione S-transferase theta-1
  4. Pathway

    Ranitidine H2 Anti-Histamine Action Pathway

    smpdb.ca/view/SMP0122729
    Drug action

    Ranitidine is an histamine H2 receptor antagonist used to treat stomach ulcers and Gastroesophageal Reflux Disease (GERD). After being taken orally, it is absorbed in the GI tract and travels through the blood to get to the stomach epith...

    Drugs: ATP · Ranitidine · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
  5. Pathway

    Cimetidine H2 Anti-Histamine Action Pathway

    smpdb.ca/view/SMP0123152
    Drug action

    Cimetidine is an H2 receptor antagonist drug that is mainly used to treat peptic ulcers and heartburns. It works by acting as a competitive inhibitor and blocks the action of histamine on Histamine H2 receptors. This ultimately reduces g...

    Drugs: ATP · Cimetidine · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
  6. Drug

    Guanidine

    go.drugbank.com/drugs/DB00536
    Approved

    (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC. … It is also used in laboratory research as a protein denaturant.

    Categories: MATE 1 Substrates, MATE 2 Substrates
  7. Drug

    Fluorescein

    go.drugbank.com/drugs/DB00693
    ApprovedInvestigational

    (From Merck Index, 12th ed; American Medical Association Drug Evaluations; 1995, p2275) … A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal

    Categories: Heterocyclic Compounds, 3-Ring, Compounds used in a research, industrial, or household settingSynonyms: D&C Yellow No. 7, 9-(o-carboxyphenyl)-6-hydroxy-3-isoxanthenone
  8. Drug

    Ethchlorvynol

    go.drugbank.com/drugs/DB00189
    ApprovedIllicitWithdrawn

    Ethchlorvynol is a sedative and hypnotic drug. It has been used to treat insomnia, but has been largely superseded and is only offered where an intolerance or allergy to other drugs exists.

    Synonyms: 1-chloro-3-ethyl-1-penten-4-yn-3-ol, 1-Chloro-3-ethyl-pent-1-en-4-yn-3-ol
  9. Pathway

    Metiamide H2 Anti-Histamine Action Pathway

    smpdb.ca/view/SMP0123167
    Drug action

    Metiamide is an histamine H2 receptor antagonist used to treat stomach ulcers and Gastroesophageal Reflux Disease (GERD). After being taken orally, it is absorbed in the GI tract and travels through the blood to get to the stomach epithe...

    Drugs: ATP · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate · Metiamide
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
  10. Pathway

    Roxatidine Acetate H2 Anti-Histamine Action Pathway

    smpdb.ca/view/SMP0123168
    Drug action

    Roxatidine Acetate is an histamine H2 receptor antagonist used to treat stomach ulcers and Gastroesophageal Reflux Disease (GERD). After being taken orally, it is absorbed in the GI tract and travels through the blood to get to the stoma...

    Drugs: ATP · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate · Roxatidine acetate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short