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Metabotropic glutamate receptor 7
go.drugbank.com/bio_entities/BE0000834TargetHumansG protein-coupled receptor activated by glutamate that regulates axon outgrowth through the MAPK-cAMP-PKA signaling pathway during neuronal development (PubMed:33500274).
Polypeptides: Metabotropic glutamate receptor 7Hydroxycarboxylic acid receptor 3
go.drugbank.com/bio_entities/BE0000836TargetHumansG protein-coupled receptor for 3-hydroxyoctanoate, a fatty acid beta-oxidation intermediate. … Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet (PubMed:12522134)
Polypeptides: Hydroxycarboxylic acid receptor 3Synonyms: Niacin receptor 2, Nicotinic acid receptor 2Proteinase-activated receptor 1
go.drugbank.com/bio_entities/BE0000928TargetHumansHigh affinity receptor that binds the activated thrombin, leading to calcium release from intracellular stores (PubMed:1672265, PubMed:8136362). … The thrombin-activated receptor signaling pathway is mediated through PTX-insensitive G proteins, activation of phospholipase C resulting in the production of 1D-myo-inositol 1,4,5-trisphosphate (InsP3
Polypeptides: Proteinase-activated receptor 1Synonyms: Thrombin receptor, Coagulation factor II receptor5-hydroxytryptamine receptor 6
go.drugbank.com/bio_entities/BE0000945TargetHumansG protein-coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (PubMed:35714614, PubMed:36989299, PubMed:37327704, PubMed
Polypeptides: 5-hydroxytryptamine receptor 6Synonyms: Serotonin receptor 6Beta-3 adrenergic receptor
go.drugbank.com/bio_entities/BE0001012TargetHumansG protein-coupled receptor for catecholamines that couples to both G(s) and G(i) proteins, leading to either activation or inhibition of adenylate cyclase and cAMP-dependent pathway, respectively (PubMed
Polypeptides: Beta-3 adrenergic receptorFunction: beta-adrenergic receptor activityOxysterols receptor LXR-beta
go.drugbank.com/bio_entities/BE0001598TargetHumansNuclear receptor that exhibits a ligand-dependent transcriptional activation activity (PubMed:25661920).
Polypeptides: Oxysterols receptor LXR-betaSynonyms: Liver X receptor beta, Nuclear receptor NEREstrogen-related receptor gamma
go.drugbank.com/bio_entities/BE0002088TargetHumansOrphan receptor that acts as a transcription activator in the absence of bound ligand.
Polypeptides: Estrogen-related receptor gammaSynonyms: Estrogen receptor-related protein 3, Nuclear receptor subfamily 3 group B member 3Metabotropic glutamate receptor 3
go.drugbank.com/bio_entities/BE0002342TargetHumansG protein-coupled receptor for glutamate.
Polypeptides: Metabotropic glutamate receptor 3Melanocyte-stimulating hormone receptor
go.drugbank.com/bio_entities/BE0002447TargetHumansG protein-coupled receptor that binds melanocyte-stimulating hormones (alpha, beta, and gamma-MSH) and adrenocorticotropic hormone/ACTH, which are peptide products of the POMC precursor protein (PubMed … MC1R interacts with G protein-coupled receptor opsin 3/OPN3, which couples to G(i) proteins and inhibits the alpha-MSH-induced cAMP response, thereby reducing melanin synthesis (PubMed:31097585).
Polypeptides: Melanocyte-stimulating hormone receptorSynonyms: Melanocortin receptor 1Anthrax toxin receptor 2
go.drugbank.com/bio_entities/BE0003223TargetHumansNecessary for cellular interactions with laminin and the extracellular matrix
Polypeptides: Anthrax toxin receptor 2Function: transmembrane signaling receptor activity